- |||||||||| Erbitux (cetuximab) / Eli Lilly
Enrollment closed, Trial primary completion date, Metastases: Nordic 8 - A Phase II Trial (clinicaltrials.gov) - Aug 27, 2018 P2, N=180, Active, not recruiting, Initiation date: Nov 2016 --> Nov 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2019
- |||||||||| Avastin (bevacizumab) / Roche
Trial completion, Enrollment change, Combination therapy: FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer (clinicaltrials.gov) - Aug 22, 2018 P1/2, N=50, Completed, Trial completion date: Feb 2022 --> May 2022 | Initiation date: Jul 2018 --> Oct 2018 | Trial primary completion date: Feb 2022 --> May 2022 Active, not recruiting --> Completed | N=35 --> 50
- |||||||||| Avastin (bevacizumab) / Roche
New P2 trial, Metastases: A Study of Bevacizumab, Infusional Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab, Infusional Fluorouracil, Leucovorin, and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer (clinicaltrials.gov) - Aug 21, 2018 P2, N=120, Not yet recruiting,
- |||||||||| Oncaspar liquid (pegaspargase) / Servier
Trial completion date: Treatment of Acute Lymphoblastic Leukemia in Children (clinicaltrials.gov) - Aug 21, 2018 P3, N=800, Active, not recruiting, N=33 --> 0 | Not yet recruiting --> Withdrawn Trial completion date: Jun 2018 --> Jun 2019
- |||||||||| Avastin (bevacizumab) / Roche
Enrollment change, Trial withdrawal: DCE-MRI PET Bevacizumab Study in Rectal Cancer (clinicaltrials.gov) - Aug 21, 2018 P2, N=0, Withdrawn, Active, not recruiting --> Completed N=30 --> 0 | Active, not recruiting --> Withdrawn
- |||||||||| 5-fluorouracil / Generic mfg., leucovorin calcium / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer (clinicaltrials.gov) - Aug 16, 2018 P2, N=5, Terminated, Trial completion date: Jul 2018 --> Jan 2019 N=35 --> 5 | Recruiting --> Terminated | Trial completion date: Aug 2017 --> Mar 2017 | Trial primary completion date: Aug 2017 --> Mar 2017; Re-eval of patient population
- |||||||||| Enrollment closed, Trial completion date, Trial primary completion date: Second Line Chemotherapy FOLFIRINOX in Irresectable Cholangiocarcinoma (clinicaltrials.gov) - Aug 16, 2018
P2, N=30, Active, not recruiting, N=35 --> 5 | Recruiting --> Terminated | Trial completion date: Aug 2017 --> Mar 2017 | Trial primary completion date: Aug 2017 --> Mar 2017; Re-eval of patient population Recruiting --> Active, not recruiting | Trial completion date: Jan 2018 --> Dec 2018 | Trial primary completion date: Jan 2018 --> Oct 2018
- |||||||||| Avastin (bevacizumab) / Roche
Trial primary completion date, Metastases: Study of Vitamin D in Untreated Metastatic Colorectal Cancer (clinicaltrials.gov) - Aug 14, 2018 P2, N=120, Active, not recruiting, Recruiting --> Active, not recruiting | Trial completion date: Jan 2018 --> Dec 2018 | Trial primary completion date: Jan 2018 --> Oct 2018 Trial primary completion date: Mar 2018 --> Dec 2018
- |||||||||| Enrollment open: QUILT-3.080: NANT Pancreatic Cancer Vaccine (clinicaltrials.gov) - Aug 10, 2018
P1b/2, N=173, Recruiting, Trial completion date: Nov 2018 --> Nov 2019 | Trial primary completion date: Nov 2018 --> Nov 2019 Not yet recruiting --> Recruiting
- |||||||||| 5-fluorouracil / Generic mfg., leucovorin calcium / Generic mfg., sorafenib / Generic mfg.
Trial completion date, Combination therapy, Metastases: Sorafenib + mFOLFOX for Hepatocellular Carcinoma (clinicaltrials.gov) - Aug 9, 2018 P2, N=40, Active, not recruiting, Trial completion date: Sep 2018 --> Sep 2019 | Trial primary completion date: Sep 2018 --> Sep 2019 Trial completion date: Dec 2018 --> Dec 2019
- |||||||||| Rubraca (rucaparib) / Pharma& Schweiz, Onivyde (nanoliposomal irinotecan) / Servier, Ipsen
Trial completion date, Trial initiation date, BRCA Biomarker, PARP Biomarker, Metastases: Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer (clinicaltrials.gov) - Aug 6, 2018 P2, N=110, Not yet recruiting, Not yet recruiting --> Recruiting Trial completion date: Dec 2021 --> Dec 2022 | Initiation date: May 2018 --> Aug 2018
- |||||||||| spartalizumab (PDR001) / Novartis
Enrollment change, Trial completion date, Trial termination, Trial primary completion date, Combination therapy, Metastases: PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer (clinicaltrials.gov) - Aug 3, 2018 P1, N=1, Terminated, Trial completion date: Dec 2021 --> Dec 2022 | Initiation date: May 2018 --> Aug 2018 N=92 --> 1 | Trial completion date: Jun 2019 --> Jan 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2019 --> Jan 2018; The study was terminated early due to company decision.
- |||||||||| Trial completion date, Metastases: FLOT4: 5-FU, Leucovorin, Oxaliplatin and Docetaxel (FLOT) Versus Epirubicin, Cisplatin and 5-FU (ECF) in Patients With Locally Advanced, Resectable Gastric Cancer (clinicaltrials.gov) - Aug 2, 2018
P2/3, N=716, Active, not recruiting, N=92 --> 1 | Trial completion date: Jun 2019 --> Jan 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2019 --> Jan 2018; The study was terminated early due to company decision. Trial completion date: Jun 2017 --> Sep 2018
- |||||||||| Trial completion, Enrollment change, Trial completion date, Trial primary completion date, Combination therapy: Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma (clinicaltrials.gov) - Aug 1, 2018
P2, N=6, Completed, Recruiting --> Active, not recruiting | N=21 --> 10 | Trial completion date: Jun 2018 --> Feb 2019 Recruiting --> Completed | N=26 --> 6 | Trial completion date: Jun 2021 --> Jun 2018 | Trial primary completion date: Jun 2020 --> Jun 2018
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