- |||||||||| Rituxan (rituximab) / Roche
Enrollment closed, Trial completion date, Trial primary completion date: LeMLAR: Lenalidomide, MTX, Ara-C and Rituximab in Relapsed Aggressive B-cell Lymphomas (clinicaltrials.gov) - Mar 15, 2019 P1/2, N=37, Active, not recruiting, Recruiting --> Active, not recruiting | Trial completion date: Jun 2019 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Jun 2019
- |||||||||| navicixizumab (OMP-305B83) / Feng Biosci
Enrollment change, Trial termination, Trial primary completion date, Metastases: A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer (clinicaltrials.gov) - Mar 13, 2019 P1b, N=16, Terminated, N=155 --> 235 N=30 --> 16 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2019 --> Sep 2018
- |||||||||| Trial completion date, Metastases: FLOT4: 5-FU, Leucovorin, Oxaliplatin and Docetaxel (FLOT) Versus Epirubicin, Cisplatin and 5-FU (ECF) in Patients With Locally Advanced, Resectable Gastric Cancer (clinicaltrials.gov) - Mar 8, 2019
P2/3, N=716, Active, not recruiting, Not yet recruiting --> Recruiting Trial completion date: Sep 2018 --> May 2019
- |||||||||| Avastin (bevacizumab) / Roche, Vectibix (panitumumab) / Amgen
Enrollment closed, Trial completion date, Trial primary completion date: CCRe-IV: Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases (clinicaltrials.gov) - Mar 1, 2019 P4, N=336, Active, not recruiting, Trial completion date: Aug 2020 --> May 2021 Recruiting --> Active, not recruiting | Trial completion date: Nov 2018 --> Jun 2019 | Trial primary completion date: Nov 2018 --> Jun 2017
- |||||||||| Trial completion, Enrollment change, Trial completion date, Surgery: GCC 1324: Borderline Pancreas Study: FOLFIRINOX +SBRT (clinicaltrials.gov) - Feb 28, 2019
P1, N=8, Completed, Active, not recruiting --> Recruiting | Trial completion date: Jun 2019 --> Sep 2019 | Trial primary completion date: Jun 2019 --> Sep 2019 Recruiting --> Completed | N=20 --> 8 | Trial completion date: Dec 2020 --> Sep 2018
- |||||||||| GVAX Pancreas (allogeneic GM-CSF-secreting tumor cells) / Novartis, Yervoy (ipilimumab) / BMS
Enrollment closed, Trial completion date, Trial primary completion date, Combination therapy, Metastases: FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer (clinicaltrials.gov) - Feb 25, 2019 P2, N=83, Active, not recruiting, Active, not recruiting --> Terminated | Trial primary completion date: Dec 2016 --> Jul 2016; Company decision Suspended --> Active, not recruiting | Trial completion date: Dec 2019 --> Jan 2021 | Trial primary completion date: Jan 2019 --> Jan 2021
- |||||||||| davamotecan pegadexamer (EP0057) / Ellipses Pharma
Enrollment change, Trial completion date, Trial termination, Combination therapy, Metastases: Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors (clinicaltrials.gov) - Feb 25, 2019 P1, N=41, Terminated, Suspended --> Active, not recruiting | Trial completion date: Dec 2019 --> Jan 2021 | Trial primary completion date: Jan 2019 --> Jan 2021 N=61 --> 41 | Trial completion date: Dec 2017 --> May 2018 | Active, not recruiting --> Terminated; Company decision
- |||||||||| Enrollment closed, Adverse events, Combination therapy, Metastases: Side Effects to FOLFOXIRI + Tocotrienol/Placebo as First Line Treatment of Metastatic Colorectal Cancer (clinicaltrials.gov) - Feb 25, 2019
P2, N=70, Active, not recruiting, N=61 --> 41 | Trial completion date: Dec 2017 --> May 2018 | Active, not recruiting --> Terminated; Company decision Recruiting --> Active, not recruiting
- |||||||||| Trial completion date, Trial primary completion date: Colon Neoadjuvant FOLFOXIRI Study (clinicaltrials.gov) - Feb 22, 2019
P2, N=40, Recruiting, Recruiting --> Active, not recruiting Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019
- |||||||||| Zaltrap (ziv-aflibercept IV) / Sanofi
Enrollment closed, Enrollment change, Trial primary completion date, Metastases: MINOAS: Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment (clinicaltrials.gov) - Feb 22, 2019 P2, N=31, Active, not recruiting, Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019 Recruiting --> Active, not recruiting | N=89 --> 31 | Trial primary completion date: Jan 2019 --> Oct 2018
- |||||||||| Teysuno (gimeracil/oteracil/tegafur) / Nordic Group, Otsuka
Trial completion date, Trial primary completion date, Metastases: MATEO: Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer (clinicaltrials.gov) - Feb 20, 2019 P2, N=400, Recruiting, Recruiting --> Active, not recruiting | N=89 --> 31 | Trial primary completion date: Jan 2019 --> Oct 2018 Trial completion date: Sep 2018 --> Jul 2020 | Trial primary completion date: Sep 2018 --> Apr 2020
- |||||||||| Avastin (bevacizumab) / Roche
Enrollment closed, Trial completion date, Trial primary completion date, Combination therapy: Avastin/FOLFIRI in Combination With Curcumin in Colorectal Cancer Patients With Unresectable Metastasis (clinicaltrials.gov) - Feb 19, 2019 P2, N=50, Active, not recruiting, Trial completion date: Jan 2024 --> Jul 2023 | Trial primary completion date: Oct 2018 --> Dec 2019 Enrolling by invitation --> Active, not recruiting | Trial completion date: Mar 2019 --> Dec 2019 | Trial primary completion date: May 2017 --> Jun 2019
- |||||||||| 5-fluorouracil / Generic mfg., leucovorin calcium / Generic mfg., irinotecan / Generic mfg.
Trial completion date, Trial initiation date, Trial primary completion date, Metastases: High-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28 (clinicaltrials.gov) - Feb 15, 2019 P2, N=90, Recruiting, Suspended --> Recruiting Trial completion date: Nov 2021 --> Mar 2022 | Initiation date: Nov 2018 --> Mar 2019 | Trial primary completion date: Nov 2018 --> Mar 2019
- |||||||||| EGFR bi-armed autologous activated T cells / Barbara Ann Karmanos Cancer Institute
Trial completion date, Trial primary completion date, Metastases: Anti-CD3 x Anti-Erbitux (clinicaltrials.gov) - Feb 12, 2019 P1, N=30, Active, not recruiting, Phase classification: P1/2 --> P1 | N=57 --> 39 Trial completion date: Jun 2019 --> Jun 2021 | Trial primary completion date: Jan 2019 --> Jan 2021
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