- |||||||||| pegylated liposomal doxorubicin / Generic mfg., cyclophosphamide / Generic mfg., epirubicin / Generic mfg.
Enrollment closed, Trial completion date, Trial primary completion date: A Study of Pegylated Liposomal Doxorubicin and Cyclophosphamide in Her2-negative Stage I and II Breast Cancer Patients (clinicaltrials.gov) - Aug 22, 2019 P2, N=254, Active, not recruiting, Recruiting --> Active, not recruiting | Trial completion date: Aug 2018 --> May 2023 | Trial primary completion date: Jul 2018 --> Oct 2019
- |||||||||| Imfinzi (durvalumab) / AstraZeneca
Enrollment open, Trial initiation date, Combination therapy, Tumor mutational burden, IO biomarker, Metastases: Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, (DURVA+ Study) (clinicaltrials.gov) - Aug 19, 2019 P2, N=115, Recruiting, Recruiting --> Active, not recruiting | Trial completion date: Aug 2018 --> May 2023 | Trial primary completion date: Jul 2018 --> Oct 2019 Not yet recruiting --> Recruiting | Initiation date: Nov 2019 --> Jun 2019
- |||||||||| Bavencio (avelumab) / EMD Serono, Trodelvy (sacituzumab govitecan-hziy) / Gilead, Mektovi (binimetinib) / Ono Pharma, Pierre Fabre, Pfizer
Enrollment open, Tumor mutational burden, Metastases: InCITe: Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer (clinicaltrials.gov) - Jul 28, 2019 P2, N=150, Recruiting, Active, not recruiting --> Completed | N=25 --> 36 Not yet recruiting --> Recruiting
- |||||||||| Neulasta (pegfilgrastim) / Roche
Trial completion date, Trial primary completion date: PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma (clinicaltrials.gov) - Jul 2, 2019 P=N/A, N=70, Active, not recruiting, Trial completion date: Jun 2021 --> Jun 2022 | Trial primary completion date: Jun 2019 --> Jun 2020 Trial completion date: Jun 2019 --> Jun 2020 | Trial primary completion date: Jun 2019 --> Jun 2020
- |||||||||| Rituxan (rituximab) / Roche, Imbruvica (ibrutinib) / AbbVie, J&J
Enrollment open: 19-C-0103: Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS) (clinicaltrials.gov) - Jun 27, 2019 P2, N=32, Recruiting, Trial completion date: Jun 2019 --> Jun 2020 | Trial primary completion date: Jun 2019 --> Jun 2020 Not yet recruiting --> Recruiting
- |||||||||| Rituxan (rituximab) / Roche, Imbruvica (ibrutinib) / AbbVie, J&J
Trial completion date: 19-C-0103: Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS) (clinicaltrials.gov) - Jun 23, 2019 P2, N=32, Not yet recruiting, Recruiting --> Active, not recruiting | Trial completion date: Feb 2021 --> Nov 2019 | Trial primary completion date: Jan 2021 --> Oct 2019 Trial completion date: Jul 2021 --> Jul 2025
- |||||||||| Focus V (anlotinib) / Advenchen, Sino Biopharm
Trial completion date, Trial primary completion date, Metastases: Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) (clinicaltrials.gov) - Jun 17, 2019 P1/2, N=48, Recruiting, Trial completion date: Jul 2021 --> Jul 2025 Trial completion date: Dec 2018 --> Dec 2020 | Trial primary completion date: Dec 2018 --> Dec 2020
- |||||||||| Bavencio (avelumab) / EMD Serono, Trodelvy (sacituzumab govitecan-hziy) / Gilead, Mektovi (binimetinib) / Ono Pharma, Pierre Fabre, Pfizer
New P2 trial, Tumor mutational burden, Metastases: InCITe: Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer (clinicaltrials.gov) - Jun 2, 2019 P2, N=150, Not yet recruiting,
- |||||||||| Rituxan (rituximab) / Roche, Imbruvica (ibrutinib) / AbbVie, J&J
New P2 trial: 19-C-0103: Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS) (clinicaltrials.gov) - May 28, 2019 P2, N=32, Not yet recruiting,
- |||||||||| pegylated liposomal doxorubicin / Generic mfg.
Enrollment closed, Trial completion date, Trial primary completion date: CAELYX (clinicaltrials.gov) - May 1, 2019 P2, N=63, Active, not recruiting, N=98 --> 214 | Trial completion date: Jul 2021 --> Dec 2021 | Trial primary completion date: Jul 2020 --> Dec 2020 Recruiting --> Active, not recruiting | Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Nov 2018 --> Nov 2019
- |||||||||| Avastin (bevacizumab) / Roche, Torisel (temsirolimus) / Pfizer
Trial completion, Trial completion date, Trial primary completion date: Doxil, Bevacizumab and Temsirolimus Trial (clinicaltrials.gov) - Apr 20, 2019 P1, N=200, Completed, Trial completion date: Oct 2019 --> Oct 2020 | Trial primary completion date: Oct 2018 --> Oct 2019 Active, not recruiting --> Completed | Trial completion date: Aug 2019 --> Mar 2019 | Trial primary completion date: Aug 2019 --> Mar 2019
- |||||||||| Adcetris (brentuximab vedotin) / Seagen, Takeda
Trial completion date, Trial primary completion date: Brentuximab for Newly Diagnosed Hodgkin Disease (clinicaltrials.gov) - Mar 13, 2019 P2, N=40, Recruiting, N=14 --> 0 | Trial completion date: Dec 2020 --> Mar 2019 | Recruiting --> Withdrawn | Trial primary completion date: Dec 2019 --> Mar 2019 Trial completion date: Jun 2019 --> Jun 2020 | Trial primary completion date: Dec 2018 --> Dec 2019
- |||||||||| pegylated liposomal doxorubicin / Generic mfg., paclitaxel / Generic mfg.
Trial completion, Enrollment change, Trial completion date, Real-world evidence, Real-world effectiveness, Real-world: Real-World Effectiveness of PLD in Platinum- Sensitive Recurrent Ovarian Cancer (clinicaltrials.gov) - Feb 28, 2019 P=N/A, N=432, Completed, Trial completion date: May 2019 --> Sep 2021 Recruiting --> Completed | N=900 --> 432 | Trial completion date: Apr 2019 --> Dec 2018
- |||||||||| pegylated liposomal doxorubicin / Generic mfg.
Trial primary completion date, Metastases: Metronomic PLD in Patients With Primary Endocrine Resistant ABC (clinicaltrials.gov) - Feb 16, 2019 P2, N=46, Recruiting, Trial completion date: Feb 2019 --> Jun 2020 | Trial primary completion date: Nov 2018 --> Jun 2019 Trial primary completion date: Dec 2018 --> Dec 2019
- |||||||||| Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche, Imbruvica (ibrutinib) / AbbVie, J&J
Trial completion date: Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma (clinicaltrials.gov) - Jan 22, 2019 P1, N=52, Recruiting, Trial completion date: Oct 2019 --> Oct 2020 Trial completion date: Jun 2022 --> Jun 2023
- |||||||||| Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche, Imbruvica (ibrutinib) / AbbVie, J&J
Trial completion date: Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma (clinicaltrials.gov) - Jan 18, 2019 P1, N=52, Recruiting, Trial completion date: Jun 2022 --> Jun 2023 Trial completion date: Jun 2023 --> Jun 2022
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