- |||||||||| Selectikine (EMD 521873) / EMD Serono
Enrollment closed, Enrollment change, Trial primary completion date, Combination therapy, Metastases: EMR 062235-005: MSB0010445 and Stereotactic Body Radiation Therapy in Advanced Melanoma (clinicaltrials.gov) - Apr 16, 2015 P2, N=12, Active, not recruiting, Recruiting --> Active, not recruiting | N=86 --> 12 | Trial primary completion date: Jan 2016 --> Feb 2015
- |||||||||| Yervoy (ipilimumab) / Ono Pharma, BMS
Trial primary completion date, Combination therapy, Metastases: Ipilimumab and Lenalidomide in Advanced Cancer (clinicaltrials.gov) - Apr 14, 2015 P1, N=101, Recruiting, N=260 --> 440 Trial primary completion date: Mar 2016 --> Mar 2017
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Enrollment change, Trial primary completion date, PD(L)-1 Biomarker, IO biomarker: CheckMate 040: An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer (clinicaltrials.gov) - Apr 9, 2015 P1, N=405, Recruiting, Recruiting --> Active, not recruiting | N=100 --> 150 | Trial primary completion date: Dec 2015 --> Dec 2018 N=250 --> 405 | Trial primary completion date: May 2017 --> Jul 2018
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Biomarker, Enrollment open, Monotherapy, PD(L)-1 Biomarker, IO biomarker: CheckMate 038: PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma (clinicaltrials.gov) - Mar 2, 2015 P1, N=160, Recruiting, Initiation date: Jan 2014 --> Oct 2014 Active, not recruiting --> Recruiting
- |||||||||| Biomarker, Trial primary completion date, PD(L)-1 Biomarker, IO biomarker: Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery (clinicaltrials.gov) - Feb 27, 2015
P1, N=40, Recruiting, Active, not recruiting --> Recruiting Trial primary completion date: Feb 2015 --> Jun 2016
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Biomarker, Enrollment closed, Monotherapy, PD(L)-1 Biomarker, IO biomarker: CheckMate 038: PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma (clinicaltrials.gov) - Feb 27, 2015 P1, N=160, Active, not recruiting, Trial primary completion date: Feb 2015 --> Jun 2016 Not yet recruiting --> Active, not recruiting
- |||||||||| Yervoy (ipilimumab) / Ono Pharma, BMS
Enrollment open, Trial initiation date, Trial primary completion date, Adverse events: Ipilimumab 12-month Intensive Pharmacovigilance Protocol (clinicaltrials.gov) - Feb 23, 2015 P=N/A, N=30, Recruiting, Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Initiation date: Jan 2014 --> Dec 2012 | Trial primary completion date: Jan 2015 --> Oct 2015
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Trial primary completion date, Monotherapy, PD(L)-1 Biomarker: Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012) (clinicaltrials.gov) - Feb 9, 2015 P1, N=412, Recruiting, Suspended --> Recruiting Trial primary completion date: Nov 2016 --> Jul 2017
- |||||||||| Trial initiation date, Trial primary completion date: Adoptive Therapy Using Antigen-Specific CD4 T-Cells (clinicaltrials.gov) - Feb 9, 2015
P1, N=12, Not yet recruiting, Trial primary completion date: Nov 2016 --> Jul 2017 Initiation date: Sep 2014 --> Jul 2015 | Trial primary completion date: Sep 2017 --> Jul 2018
- |||||||||| Proleukin (aldesleukin) / Merck (MSD), Novartis, Iovance Biotherap, Yervoy (ipilimumab) / BMS
Enrollment open, Trial initiation date, Trial primary completion date, Metastases: CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma (clinicaltrials.gov) - Jan 26, 2015 P2, N=20, Recruiting, N=90 --> 245 | Trial primary completion date: May 2016 --> May 2017 Not yet recruiting --> Recruiting | Initiation date: Apr 2015 --> Jan 2015 | Trial primary completion date: Apr 2019 --> Jan 2019
- |||||||||| lirilumab (BMS-986015) / Innate, BMS, Ono Pharma, Yervoy (ipilimumab) / BMS
Enrollment closed, Trial primary completion date, Combination therapy, Metastases: Safety Study of BMS-986015 (Anti-KIR) in Combination With Ipilimumab in Subjects With Selected Advanced Tumor (clinicaltrials.gov) - Jan 26, 2015 P1, N=125, Active, not recruiting, Not yet recruiting --> Recruiting | Initiation date: Apr 2015 --> Jan 2015 | Trial primary completion date: Apr 2019 --> Jan 2019 Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2016 --> Mar 2016
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