- |||||||||| Yervoy (ipilimumab) / Ono Pharma, BMS
Enrollment open, Adverse events: Yervoy Pregnancy Surveillance Study (clinicaltrials.gov) - Nov 14, 2016 P=N/A, N=10, Recruiting, Not yet recruiting --> Recruiting
- |||||||||| Xpovio (selinexor) / Karyopharm
Enrollment closed, Enrollment change, PARP Biomarker, PD(L)-1 Biomarker, IO biomarker: NCI-2015-00693: Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination with Multiple Standard Chemotherapy or Immunotherapy Agents in Patients with Advanced Malignancies (clinicaltrials.gov) - Oct 26, 2016 P1, N=88, Active, not recruiting, Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | N=470 --> 88
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Biomarker, Enrollment open, Trial initiation date, PD(L)-1 Biomarker, IO biomarker: Neoadjuvant Combination Biotherapy With Ipilimumab and Nivolumab or Nivolumab Alone (clinicaltrials.gov) - Oct 26, 2016 P1/2, N=66, Recruiting, Recruiting --> Active, not recruiting | N=470 --> 88 Not yet recruiting --> Recruiting | Initiation date: Apr 2016 --> Oct 2016
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Enrollment closed, Trial primary completion date, Monotherapy, PD(L)-1 Biomarker, IO biomarker: MAPS2: Nivolumab Monotherapy or Nivolumab Plus Ipilimumab, for Unresectable Malignant Pleural Mesothelioma (MPM) Patients (clinicaltrials.gov) - Oct 25, 2016 P2, N=125, Active, not recruiting, Not yet recruiting --> Recruiting | Initiation date: Apr 2016 --> Oct 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2017 --> May 2017
- |||||||||| Erbitux (cetuximab) / Eli Lilly, EMD Serono, Yervoy (ipilimumab) / BMS
Enrollment closed, Metastases: Ipilimumab, Cetuximab, and Intensity-Modulated Radiation Therapy in Treating Patients With Previously Untreated Stage III-IVB Head and Neck Cancer (clinicaltrials.gov) - Oct 13, 2016 P1, N=18, Active, not recruiting, Trial primary completion date: Sep 2017 --> Oct 2020 Recruiting --> Active, not recruiting
- |||||||||| Skyclarys (omaveloxolone) / Biogen
Phase classification, Trial primary completion date: RTA 408 Capsules in Patients With Melanoma - REVEAL (clinicaltrials.gov) - Oct 6, 2016 P1b/2, N=84, Recruiting, Phase classification: P1/2 --> P1b/2 Phase classification: P1/2 --> P1b/2 | Trial primary completion date: Mar 2017 --> Jun 2017
- |||||||||| Opdivo (nivolumab) / BMS, Yervoy (ipilimumab) / BMS
Enrollment closed, Tumor mutational burden, PD(L)-1 Biomarker, IO biomarker: OpACIN: Study to Identify the Optimal Adjuvant Combination Scheme of Ipilimumab and Nivolumab in Melanoma Patients (clinicaltrials.gov) - Oct 4, 2016 P1, N=20, Active, not recruiting, Phase classification: P1/2 --> P1b/2 | Trial primary completion date: Mar 2017 --> Jun 2017 Recruiting --> Active, not recruiting
- |||||||||| varlilumab (CDX 1127) / Celldex, rasdegafusp alfa (CDX-1401) / Celldex
Enrollment closed, Enrollment change, Combination therapy, Metastases: A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma (clinicaltrials.gov) - Oct 3, 2016 P2, N=9, Active, not recruiting, Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | N=100 --> 9
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