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35 News |  |
- ||| brivoligide (AYX1) / Merck (MSD)
My colleagues are great; adding their own decorations! https://t.co/7ayxG1Tczm (Twitter) - Jan 10, 2022
- | brivoligide (AYX1) / Merck (MSD)
Journal: MicroRNA-124-3p attenuates the development of nerve injury-induced neuropathic pain by targeting early growth response 1 in the dorsal root ganglia and spinal dorsal horn. (Pubmed Central) - Nov 16, 2021
Prior i.t. injection of Egr1 decoy AYX1 inhibited the expression of Egr1 and attenuated the neuropathic pain-like hypersensitivity following SNL...Together, our results suggest that the miR-124-3p-regulated Egr1 expression in the DRG and dorsal horn contributes to the development of neuropathic pain. Targeting miR-124-3p might be a promising therapeutic strategy in the treatment of chronic pain.
- |||| brivoligide (AYX1) / Merck (MSD)
Clinical: What are universities doing to support women in academia during #COVID19? Is it enough? Featuring @MichelleCardel and others, via @NYTimes #WomenInSTEM #womeninacademia @Momademia #academicparents https://t.co/KEB0AyX1vX (Twitter) - Oct 6, 2020
- | brivoligide (AYX1) / Merck (MSD)
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores (clinicaltrials.gov) - Jul 13, 2020
P2, N=0, Withdrawn, Sponsor: Adynxx, Inc.
Targeting miR-124-3p might be a promising therapeutic strategy in the treatment of chronic pain. N=122 --> 0 | Trial completion date: Jun 2020 --> Feb 2022 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2020 --> Jan 2022
- | brivoligide (AYX1) / Merck (MSD)
Enrollment change, Trial completion date, Trial initiation date, Trial withdrawal, Trial primary completion date: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores (clinicaltrials.gov) - Jul 13, 2020
P2, N=0, Withdrawn, Sponsor: Adynxx, Inc.
N=122 --> 0 | Trial completion date: Jun 2020 --> Feb 2022 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2020 --> Jan 2022 N=126 --> 0 | Trial completion date: Dec 2020 --> Feb 2022 | Initiation date: Dec 2019 --> Jan 2021 | Not yet recruiting --> Withdrawn | Trial primary completion date: Dec 2020 --> Jan 2022
- || brivoligide (AYX1) / Merck (MSD)
Duffy, Alonso Ancira 🤔💺 #كتابات_منيره #tele2019 #29AEC https://t.co/AyX1hIGoFk (Twitter) - Oct 23, 2019
- | brivoligide (AYX1) / Merck (MSD)
New P2 trial: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores (clinicaltrials.gov) - Sep 25, 2019
P2, N=126, Not yet recruiting, Sponsor: Adynxx, Inc.
- || brivoligide (AYX1) / Merck (MSD)
Trial completion date, Trial initiation date, Trial primary completion date: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores (clinicaltrials.gov) - Jul 5, 2019
P2, N=122, Not yet recruiting, Sponsor: Adynxx, Inc.
N=126 --> 0 | Trial completion date: Dec 2020 --> Feb 2022 | Initiation date: Dec 2019 --> Jan 2021 | Not yet recruiting --> Withdrawn | Trial primary completion date: Dec 2020 --> Jan 2022 Trial completion date: Feb 2020 --> Jun 2020 | Initiation date: May 2019 --> Oct 2019 | Trial primary completion date: Feb 2020 --> Jun 2020
- |||| brivoligide (AYX1) / Merck (MSD)
New P2 trial: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores (clinicaltrials.gov) - Jan 9, 2019
P2, N=122, Not yet recruiting, Sponsor: Adynxx, Inc.
- |||| brivoligide (AYX1) / Merck (MSD)
Trial completion, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Jan 9, 2018
P2, N=210, Completed, Sponsor: Adynxx, Inc.
Trial completion date: Feb 2020 --> Jun 2020 | Initiation date: May 2019 --> Oct 2019 | Trial primary completion date: Feb 2020 --> Jun 2020 Active, not recruiting --> Completed
- ||| brivoligide (AYX1) / Merck (MSD)
Enrollment closed, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Oct 6, 2017
P2, N=210, Active, not recruiting, Sponsor: Adynxx, Inc.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- || brivoligide (AYX1) / Merck (MSD)
Trial primary completion date, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Apr 25, 2017
P2, N=200, Recruiting, Sponsor: Adynxx, Inc.
Recruiting --> Active, not recruiting Trial primary completion date: Aug 2017 --> Nov 2017
- |||| brivoligide (AYX1) / Merck (MSD)
Enrollment open, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Feb 13, 2017
P2, N=200, Recruiting, Sponsor: Adynxx, Inc.
Trial primary completion date: Aug 2017 --> Nov 2017 Not yet recruiting --> Recruiting
- ||| brivoligide (AYX1) / Merck (MSD)
Trial initiation date, Trial primary completion date, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Oct 12, 2016
P2, N=200, Not yet recruiting, Sponsor: Adynxx, Inc.
Not yet recruiting --> Recruiting Initiation date: Aug 2016 --> Feb 2017 | Trial primary completion date: Mar 2017 --> Aug 2017
- ||||| brivoligide (AYX1) / Merck (MSD)
New P2 trial, Surgery: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Jun 21, 2016
P2, N=200, Not yet recruiting, Sponsor: Adynxx, Inc.
- |||| brivoligide (AYX1) / Merck (MSD)
Trial completion, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Aug 11, 2015
P2, N=120, Completed, Sponsor: Adynxx, Inc.
Initiation date: Aug 2016 --> Feb 2017 | Trial primary completion date: Mar 2017 --> Aug 2017 Active, not recruiting --> Completed
- ||| brivoligide (AYX1) / Merck (MSD)
Enrollment closed, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - May 27, 2015
P2, N=120, Active, not recruiting, Sponsor: Adynxx, Inc.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- |||| brivoligide (AYX1) / Merck (MSD)
Enrollment open, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - May 20, 2014
P2, N=120, Recruiting, Sponsor: Adynxx, Inc.
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- ||||| brivoligide (AYX1) / Merck (MSD)
New P2 trial, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Mar 5, 2014
P2, N=120, Not yet recruiting, Sponsor: Adynxx, Inc.
- |||| brivoligide (AYX1) / Merck (MSD)
Trial completion, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Nov 18, 2013
P2, N=102, Completed, Sponsor: Adynxx, Inc.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||||| brivoligide (AYX1) / Merck (MSD)
New P2 trial, Surgery: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery (clinicaltrials.gov) - Nov 20, 2012
P2, N=102, Completed, Sponsor: Adynxx, Inc.