| sevoflurane / Generic mfg. |
ACTRN12621001099819p: The Topical trial: Application of an anaesthetic medication to painful ulcers to evaluate the pain relief benefit and wound healing potential |
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| Not yet recruiting | 4 | 6 | | | Anaesthetic Research Department, Waikato Hospital, Anaesthetic research department- Waikato hospital, | Chronic painful non-healing Ulcers | | | | |
ACTRN12614000226606: Investigation of the effects of anaesthetic choice on ventilation-perfusion scatter and lung gas exchange. |
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| Not yet recruiting | 4 | 24 | | | Austin Health, Australian and New Zealand College of Anaesthetists | Impaired lung function under anaesthesia | | | | |
ACTRN12621001093875p: The Topical Trial: topical sevoflurane applied to chronic non-healing ulcer wounds for up to 30 days |
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| Not yet recruiting | 4 | 30 | | | Anaesthetic Research Department, Waikato Hospital, Anaesthetic research department- Waikato hospital, | Chronic painful non-healing ulcers | | | | |
ACTRN12605000677606: Cardioprotection for type II diabetic patients undergoing cardiopulmonary bypass: a comparison of 2 different anaesthetic agents. |
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| Not yet recruiting | 4 | 40 | | | Dept of Anaesthesia, St Vincent's Hospital | Postoperative myocardial damage | | | | |
| Not yet recruiting | 4 | 60 | | | Jie Ae Kim, Samsung Medical Center Clinical Research Development Program grant, CRS110-07-1 | breast cancer, partial mastectomy with sentinel lymph node dissection | | | | |
ACTRN12610000025033: The effect of propofol on emergence delirium in children after sevoflurane anaesthesia |
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| Recruiting | 4 | 250 | | | Women's and Children's Hospital, Women's and Children's Hospital, | Post anaesthetic emergence delirium in children | | | | |
ACTRN12621001093875: The Topical Trial: topical sevoflurane applied to chronic non-healing ulcer wounds for up to 30 days |
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| Recruiting | 4 | 30 | | | Anaesthetic Research Department, Waikato Hospital, Anaesthetic research department- Waikato hospital, | Chronic painful non-healing ulcers | | | | |
| Recruiting | 4 | 100 | | | HARRAN UNIVERSITY , HARRAN UNIVERSITY - SCIENTIFIC RESEARCH PROJECTS UNIT | middle ear surgery | | | | |
ChiCTR-TRC-12002788: Postoperative outcomes of dexmedetomidine, propofol or Sevoflurane anesthesia in children with cyanotic complex congenital heart defect undergoing cardiac surgery |
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| Completed | 4 | 90 | | dexmedetomidine ;propofol ;Sevoflurane | First Affiliated Hospital of Anhui Medical University, Department of Anesthesiology; Level of the institution：, 2010 Anhui Provincial Health Department medical research focused Project (Number: 2010A011) | cyanotic congenital heart disease | | | | |
ChiCTR-TRC-14004815: Sevoflurane-sparing degree of dexmedetomidine in patients with gynecological laparoscopy |
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| Completed | 4 | 40 | | intravenously infuse the same amount of normal saline ;Intravenous infusion of dexmedetomidine 1.0 ug/kg by 10 min before anesthesia induction, followed by 0.4 ug/kg/h continuous infusion to the end of the surgery | Anhui Provincial Hospital; Level of the institution：, Self-raised | patients with gynecological laparoscopy | | | | |
| Ongoing | 4 | 38 | Europe | Diprivan 1%, Sevoflurane, Emulsion for injection, Inhalation vapour, liquid, Diprivan 1%, Sevoflurane | Sussex NHS Research Consortium, Research Department, Worthing Hospital | Proximal femoral fracture | | | | |
| Ongoing | 4 | 60 | Europe | Inhalation gas, SEVORANE*INAL 250ML QUIK FIL | AZIENDA OSPEDALIERA DI PERUGIA | general anestetic inalathory also during CEC | | | | |
2007-003151-36: Sevoflurane-Remifentanil interaction: Multiple response surfaces, validation of calibration stimuli, validation of the intraoperative isobole concept and investigating remifentanil induced opioid tolerance |
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| Ongoing | 4 | 40 | Europe | sevoflurane, Remifentanil, Inhalation vapour, liquid, Powder for concentrate for solution for infusion, Sevorane, Ultiva | University Hospital Ghent | American Society of Anesthesia class I and II patients scheduled for surgery under general anesthesia | | | | |
2011-000790-31: Propofol-based or Sevoflurane-based Anesthesia Induction in Patients Undergoing Fiberoptic Tracheal Intubation for Cervical Spine Surgery: Effects on Systemic Hemodynamics and Respiratory Drive- the Blade Runner Trial Induzione dell'anestesia basata su sevofluorano o propofol in pazienti sottoposti a intubazione con fibrobroncoscopio nella chirurgia della colonna cervicale: effetti sull'emodinamica e sul pattern ventilatorio.-the Blade Runner trial |
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| Ongoing | 4 | 116 | Europe | NA, Sevoflurane, NA, Emulsion for infusion, Inhalation gas | AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA | surgery for cervical myelopathy Intervento Chirurgico per mielopatia cervicale, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
| Completed | 4 | 300 | | inhalation induction of sevoflurane in children without parents ;inhalation induction of sevoflurane in children with parents | Department of Anaesthesiology, Union Hospital, Wuhan, Hubei, China; Ministry of Health, China., Specific finance department of Ministry of Health, China. | children undergoing general anesthesia | | | | |
ChiCTR-OCC-11001411: A Research of the Effects of Different Anaesthesia Medicine and Method and the Mechanism on Postoperative Cognitive Dysfunction After Non-cardiac Surgery in the Elderly |
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| Completed | 4 | 150 | | Isoflurane ;Propofol ;Sevoflurane | The Second Affiliated Hospital of Harbin Medical University; Research project in Heilongjiang Province, Research project in Heilongjiang Province | postoperative cognitive dysfunction (POCD) | | | | |
ChiCTR-TRC-11001373: The protective effect of administration of sevoflurane during the entire procedure and pulmonary static inflation with hypothermia gas during cardiopulmonay bypass on lung function in patients undergo |
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| Completed | 4 | 80 | | receiving sevoflurane (1 minimal alveolar concentration MAC) during the entire procedure and pulmonary static inflation with hypothermia gas(10 degree C). ;receiving sevoflurane (1 MAC) during entire procedure and pulmonary static inflation with room temperature gas(24 degree C) ;receiving propofol (4-6mg/kg?h) during the entire procedure and pulmonary static inflation with hypothermia gas(10 degree C). ;receiving propofol (4-6mg/kg?h) during entire procedure and pulmonary static inflation with room temperature gas(24 degree C). | The 2nd affliated hospital of Harbin Medical University; The 2nd affliated hospital of Harbin Medical University, self-funding | mitral valve disease and aortic valve disease | | | | |
ChiCTR-TRC-11001530: A comparison of the mechanism and protective effects on liver and distant organs on patients with hepatic carcinoma and cirrhosis after hepatectomy with inflow occlusion among different anesthetics |
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| Completed | 4 | 120 | | propofol+NS, not inflow occlusion ;propofol+dexmedetomidine, inflow occlus ;propofol+dexmedetomidine, not inflow occlus ;sevoflurane, inflow occlus ;propofol+NS, inflow occlusion ;voflurane, not inflow occlus | The First Affiliated Hospital of Sun Yat-sen University; Guangdong Science and Technology Agency, Num171, Lianxin Road, Yuexiu District, Guangzhou, Guangdong Science and Technology Program | hepatic cirrhosis, hepatic carcinoma | | | | |
ChiCTR-TRC-11001509: Effect of flumazenil on recovery from sevoflurane in patients received nerve block |
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| Completed | 4 | 60 | | Patients in group flumazenil receives 0.006mg/Kg flumazenil ，diluted to 5ml by saline ;Patients in group control receives 5ml saline | West China Hospital, Sichuan University; West China Hospital, Sichuan University, self support | patients need to receive anesthetization | | | | |
ChiCTR-TRC-12002692: The effect of sufentanil on emergence agitation in preschool children undergoing sevoflurane anesthesia |
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| Completed | 4 | 80 | | sufentanil 0.15 ug/kg ;fentanyl 0.15 ug/kg | Mianyang Central Hospital, Sichuan, China; Level of the institution：, self-financing | inguinal hernia | | | | |
ChiCTR-OCH-12002169: The clinical significance of NBNA scoring and brainstem auditory evoked potential and neuron-specificenolase and S100beta portein in assessing the neurotoxicity of sevoflurane on neonates during early postoperative stage |
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| Completed | 4 | 80 | | sevoflurane exposure ;sevoflurane exposure ;sevoflurane exposure ;non sevoflurane exposure | Department of Anesthesiology, Maternal and Child Healthcare Hospital, Fujian; Level of the institution：, research fundation | the neurotoxicity of neonates with sevoflurane exposure | | | | |
ChiCTR-TRC-13004035: Circulating miRNA-499 and miRNA-208b indicate cardioprotection by sevoflurane anesthesia in patients undergoing OPCABG. |
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| Completed | 4 | 30 | | sevoflurane VIMA ;propofol TIVA | Xiangya Hospital of Central South University; Xiangya Hospital, Funding of Hunan provincial Science and Technology Agency (2013FJ4101) | Heart Disease | | | | |
ChiCTR-TRC-12002388: The clinical research of Dexmedetomidine-Ketamine Anesthesia on children with obstructive sleep apnea after uvulopalatopharyngoplasty |
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| Completed | 4 | 60 | | Anesthesia was maintained by Dexmedetomidine-Ketam ;Anesthesia was maintained by Sevoflurane-sufentanil | Shanghai Children's Medical Center; Shanghai Children's Medical Center, Key Project of Anhui Provincial Health Department medical research | obstructive sleep apnea | | | | |
| Completed | 4 | 60 | | Sevoflurane ;Isoflurane ;Sevoflurane ;Isoflurane ;Sevoflurane ;Sevoflurane | West China Hospital, Sichuan University; B. Braun Medical (Shanghai) Int'l Trading Co., Ltd., B. Braun anesthetic science committee | different degree of hepatic injury | | | | |
ChiCTR-TRC-12002795: Tracheal intubating conditions and apnea time after different dose of propofol during inhalation induction with sevoflurane in adults |
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| Completed | 4 | 60 | | propofol 1mg/kg was given by intravenous ;propofol 2mg/kg was given by intravenous | Department of Anesthesiology, West China Hospital, Sichuan University; Level of the institution：, Department of Anesthesiology, West China Hospital, Sichuan University | not limited | | | | |
ChiCTR-TRC-12002557: A comparison between total intravenous anaesthesia (TIVA) using propofol and remifentanil and volatile induction and maintenance of anaesthesia (VIMA) using sevoflurane on flexible fiberoptic bronchoscopy in children |
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| Completed | 4 | 50 | | total intravenous anaesthesia ;total intravenous anaesthesia | Hubei Maternal and Child Health Hospital; Hubei Maternal and Child Health Hospital, A study fund provided by the Hubei Maternal and Child Health Hospital | pneumonia | | | | |
ChiCTR-TRC-10000867: Effecet of lower MAC of sevoflurane with remifentanil on intraoperative neurologic monitoring during scoliosis surgery in children |
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| Completed | 4 | 30 | | Propofol 4-6mg/kg/h and remifentanil 0.1-0.6ug/kg/min iv. ;0.4-0.7MAC sevoflurane for inhalation and remifentanil 0.1-0.6ug/kg/min iv. | The First Affiliated Hospital to Sun Yat-sen University; Level of the institution：, National Natural Science Fund of China | Scoliosis | | | | |
2013-000119-25: improving Information Extraction from EEG on cerebral anesthetic drug effects |
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| Ongoing | 4 | 36 | Europe | ultiva, Solution for injection/infusion, , Inhalation vapour, remifentanil, propofol, sevoflurane | masimo, masimo | We will include 36 healthy volunteers (American Society of Anesthesiologists 1) stratified to age groups and randomized to different sequence of anesthesia regimen., We will include 36 healthy volunteers (American Society of Anesthesiologists 1) stratified to age groups and randomized to different sequence of anesthesia regimen., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Equipment and Supplies [E07] | | | | |
2013-001304-11: Assessing the potential benefit of the use of sevoflurane as an anesthetic during bypass surgery and subsequent recovery Evaluación del posible efecto beneficioso del uso de sevoflurano como anestésico durante cirugía de revascularización y en la recuperación posterior |
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| Ongoing | 4 | 100 | Europe | Sevoflurane, Propofol, Inhalation vapour, liquid, Emulsion for injection/infusion, SEVORANE, Propofol Lipomed Fresenius | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud, Asociación Andaluza-Extremeña de Anestesiología, Reanimación y Terapéutica del Dolor | Assessment of the beneficial effects of sevoflurane during the intraoperative and immediate postoperative myocardial revascularization surgery. Assessment will be through biochemical markers of myocardial injury and dysfunction Evaluación de los efectos beneficiosos del sevoflurano, en el intraoperatorio y postoperatorio inmediato de cirugía de revascularización miocárdica. La evaluación se hará a través de marcadores bioquímicos de lesión y disfunción miocárdica, To evaluate the protective effect on the heart function of the use of sevoflurane as a hypnotic in this surgery Evaluar el efecto protector sobre la función del corazón del uso del sevoflurano como hipnótico en esta cirugía, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2013-004582-14: Haemodynamic effects of xenon or sevoflurane anesthesia on microcirculation |
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| Ongoing | 4 | 40 | Europe | Xenon, SEVORANE, Medicinal gas, compressed, Xenon Air Liquide Medical, SEVORANE QUICK FILL 100% | Department of Anesthesiology and Perioperative Medicine, UZ Brussel | Patients with ASA III classification (left ventricular failure) undergoing implantation of a defibrillator., Patients with ASA III classification (left ventricular failure) undergoing implantation of a defibrillator., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2013-002581-39: Impact of deep neuromuscular block versus inhalation and TIVA on laparoscopic surgical workspace |
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| Ongoing | 4 | 22 | Europe | Remifentanyl, Sevoflurane, rocuronium, Remifentanyl, Sevoflurane, rocuronium, Powder for concentrate for solution for injection/infusion, Inhalation solution, Solution for injection, ULTIVA (R), SEVORANE (R), Esmeron (R) | AZ Sint Jan Brugge-Oostende AV, AZ Sint Jan Brugge-Oostende AV | Not applicable, not applicable, Not possible to specify | | | | |
ChiCTR-TRC-14004295: Does sevoflurane cause worse postoperative cognitive dysfunction than propofol after radical rectal resection in elderly patients with mild cognitive impairment? |
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| Completed | 4 | 220 | | receive sevoflurane-based general anesthesia ;receive propofol-based general anesthesia | The Affiliated Hospital of Luzhou Medical College; Level of the institution：, self-financing | postoperative cognitive dysfunction | | | | |
| Completed | 4 | 120 | | Dezocine 0.1mg/kg ;Fentanyl 1ug/kg ;saline | Mianyang Central Hospital, Sichuan, China; Level of the institution：, Self-financing | Tonsil hypertrophy/adenoidal hypertrophy | | | | |
2013-005533-20: We’re planning a large multicentre controlled randomized trial to demonstrate that volatile anesthetics vs TIVA can reduce 1 year mortality from 3% to 2% in patients undergoing CABG (either with or without cardiopulmonary bypass) and 30 days after surgery (co-primary endpoint) in patients undergoing coronary artery bypass grafting Lo studio randomizzato, multicentrico e intende paragonare due regimi anestesiologici (utilizzo di gas alogenati vs utilizzo di anestesia totalmente endovenosa “TIVA”) nell’intervento di bypass aortocoronarico (CABG) condotto con l’ausilio di circolazione extracorporea. Si vuole dimostrare la riduzione di mortalità a 1 anno dal 3% al 2% (endpoint primario) e a 30 giorni dall’intervento (endpoint co-primario) nei pazienti sottoposti a bypass aortocoronarico. |
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| Ongoing | 4 | 5200 | Europe | Inhalation solution, SEVOFLURANE, DESFLURANE, ISOFLURANE | OSPEDALE SAN RAFFAELE IRCCS, Ghent University Hospital, San Raffaele Hospital, GRANT MINISTERO DELLA SALUTE BANDO RICERCA FINALIZZATA 2010, Ghent University Hospital, San Raffaele Hospital | PATIENTS UNDERGOING CORONARY ARTERY BYOASS GRAFT SURGERY PAZIENTI SOTTOPOSTI A BYPASS AORTOCORONARICO, CORONARY ARTERY BYPASS GRAFT SURGERY INERVENTO DI BYPASS AORTOCORONARICO, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2014-004604-29: Sevoflurane versus standard general anesthesia in elective open abdominal aortic aneurism surgery |
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| Ongoing | 4 | 24 | Europe | Sevoflurane, Inhalation vapour, Emulsion for infusion, Sevoflurane, Propofol "B.Braun" | Jens Rolighed Larsen, Viborg Regional Hospital | Abdominal aortic aneurism, Abdominal aortic aneurism, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-IPR-14005470: Propofol Up-regulates MicroRNA-30b to repress Beclin-1 and Inhibits Excessive Autophagy and Apoptosis |
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| Recruiting | 4 | 30 | | Propofol ;sevoflurane | Renminthe affiliated hospital of Guangdong medical college; the affiliated hospital of Guangdong medical college, the National Natural Science Foundation of China | ischemia reperfusion | | | | |
ChiCTR-IPR-14005399: Effects of sevoflurane on ischemia-reperfusion injury in living donor kidney transplantation |
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| Recruiting | 4 | 75 | | none ;sevoflurane preconditioning ;sevoflurane postconditioning | the First Affiliated Hospital, College of Medicine, Zhejiang University; the First Affiliated Hospital, College of Medicine, Zhejiang University, the First Affiliated Hospital, College of Medicine, Zhejiang University | chronic renal failure | | | | |
ChiCTR-IPR-15006841: The effect on the body's immune system of different anesthetic and different methods of anesthesia |
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| Recruiting | 4 | 60 | | propofol/sevoflurane | Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University; Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, the National Natural Science Foundation of China (No.81371511) | liver cancer | | | | |
| Ongoing | 4 | 48 | Europe | Sevoflurane, N01, Inhalation vapour, Sevoflurane | Medical University Vienna, Department of Anesthesia, Intensive Care Medicine and Pain Management, Medical University Vienna | Renal transplantation is the curative treatment in patients with endstage kidney disease. These patients have altered intraoperativeanesthetic requirements compared with patients with maintained renalfunction. Sevoflurane is used for anesthesia in patients with end stagekidney disease. However, it is unknown if whether Sevoflurane has thesame potency as in patients with maintained renal function. Theminimum alveolar concentration is a measure of the potency of volatileanesthetics., Requirements of the inhalative anesthetics sevofluran in patients withend stage kidney disease., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR-TRC-13003631: Pharmacodynamics and accuracy evaluation of sufentanil administered by target-controlled infusion at low concentration |
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| Completed | 4 | 45 | | Anesthesia is maintained with sevoflurane mainly ;Anesthesia is maintained with sufentanil TCI (concentration 1)and sevoflurane ;Anesthesia is maintained with sufentanil TCI (concentration 2)and sevoflurane | Department of Anesthesiology, Peking University Third Hospital; Level of the institution：, Initial fund of returnee of Peking University Third Hospital | Anesthesia of laparoscopic surgery | | | | |
2015-002399-25: INCIDENCE OF POSTOPERATIVE AGITATION AFTER ANESTHESIA WITH SEVOFLURANE OR DESFLURANE IN PEDIATRIC PATIENTS. INCIDENCIA DE AGITACIÓN POSTOPERATORIA TRAS ANESTESIA CON SEVOFLURANO Y DESFLURANO EN PACIENTE PEDIATRICOS |
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| Ongoing | 4 | 120 | Europe | SEVOFLURANO, DESFLURANO, Inhalation vapour, liquid, SEVORANE, SUPRANE | Servicio de Anestesia Infantil. Hospital Universitario La Paz, SERVICIO DE ANESTESIA INFANTIL, HOSPITAL UNIVERSITARIO LA PAZ | AGITATION AFTER POSTOPERATIVE ANESTHESIA IN PEDIATRIC PATIENTS AGITACIÓN POSTOPERATORIA EN PACIENTES PEDIÃTRICOS TRAS ANESTESIA, AGITATION AFTER POSTOPERATIVE ANESTHESIA IN PEDIATRIC PATIENTS AGITACIÓN POSTOPERATORIA EN PACIENTES PEDIÃTRICOS TRAS ANESTESIA, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2004-004723-35: PRECONDITIONING EFFECT OF INALATORY ANESTHETICS EFFETTO DI PRECONDIZIONAMENTO DEGLI ANESTETICI INALATORI |
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| Ongoing | 4 | 160 | Europe | NA, NA, SEVORANE*INAL 250ML QUIK FIL, SEVORANE*INAL 250ML QUIK FIL | OSPEDALE S. RAFFAELE DI MILANO, nessun finanziamento a supporto | SEVOFLURANE USED AS ANESTETIC IN ORDER TO OBTAIN A MYOCARDIAL PROTECTION UTILIZZO DI SEVOFLURANO IN ANESTESIA AL FINE DI OTTENERE UNA PROTEZIONE MIOCARDICA | | | | |
2006-003515-44: Cardioprotective effect of sevoflurane versus propofol used during anesthesia and the postoperative period in patients undergoing coronary bypass surgery. Impact on critical care unit stay. A double-blind, randomized, controlled, prospective clinical study.Efecto cardioprotector del sevoflurano frente al propofol, utilizados durante la anestesia y el periodo postoperatorio en pacientes sometidos a cirugía de bypass coronario. Repercusión sobre la estancia en la unidad de críticos. Estudio clínico, prospectivo, controlado, randomizado y doble ciego. |
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| Ongoing | 4 | 74 | Europe | SEVORANE, DIPRIVAN 1%, JERINGA PRECARGADA, SEVORANE, DIPRIVAN 1%, JERINGA PRECARGADA | FRANCISCO JAVIER BELDA | This study will evaluate the cardioprotective effects of sevoflurane versus propofol during anesthesia and sedation of patients undergoing coronary bypass surgery in terms of maintenance of cardiac function and reduction of stay in these units.Secondary Objectives:1. To compare the possible advantages and disadvantages of both regimens in terms of preservation/improvement or pulmonary, hepatic and renal side effects. | | | | |
2006-005742-37: Randomised clinical trial of the effects of total intravenous anaesthesia (TIVA: propofol) versus volatile anaesthesia (sevoflurane-N20 induction and isoflurane-N20 maintenance) on children’s post-operative cognition, behaviour and physical morbidity. |
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| Ongoing | 4 | 360 | Europe | Propofol, SEVOFLURANE, Medical Nitrous Oxide, Isoflurane, Propofol-Lipuro 1%, Sevoflurane (Abbott Laboratories Ltd), Medical Nitrous Oxide, Isoflurane (Abbott Laboratories Ltd), Propofol-Lipuro 1%, Sevoflurane (Abbott Laboratories Ltd), Medical Nitrous Oxide, Isoflurane (Abbott Laboratories Ltd) | NHS Glasgow and Clyde / University of Glasgow | Dental caries | | | | |
2006-006295-37: A multi-site RCT comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants. |
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| Ongoing | 4 | 150 | Europe | Sevoflurane, Bupivacaine, Marcain Heavy, Levobupivacaine, Sevoflurane, N01BB01, Sevoflurane (Abbott Laboratories Ltd), Marcain Heavy, Chirocaine, Sevoflurane (Abbott Laboratories Ltd), Marcain Heavy, Chirocaine | NHS Greater Glasgow & Clyde, UMC Utrecht | Inguinal hernia in neonates and infants | | | | |
2007-007583-20: Yleisanestesian-sevofluraani-induktion aiheuttamat EEG-muutokset alle 2-vuotiailla lapsilla |
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| Ongoing | 4 | 100 | Europe | sevorane, ilokaasu | Marja-Liisa Korhonen | Tutkittavat ovat terveitä lapsia, joille tehdään kyynelteiden sondeeraus-toimenpide. | | | | |
2007-002925-64: Pharmacocinétique du sévoflurane lors d’une sédation sur 48h en Réanimation avec le système AnaConDa : étude pilote. |
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| Ongoing | 4 | 12 | Europe | SEVORANE, SEVORANE | CHU Clermont-Ferrand | Patient de Réanimation sous ventilation artificielle nécessitant une sédation de 48 h. | | | | |
2008-001052-48: A Comparison of the Post-operative analgesic effects of Propofol anaesthesia with Sevoflurane anaesthesia |
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| Ongoing | 4 | 80 | Europe | Diprivan, Sevorane, Propofol, Sevoflurane, Diprivan, Sevorane, Diprivan, Sevorane | Coombe Women and Infants University Hospital | Acute post-operative pain | | | | |
2008-002878-35: The GAS study. A multi-site RCT comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants |
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| Ongoing | 4 | 50 | Europe | SEVORANE*INAL 250ML SECUR LOCK, SEVORANE*INAL 250ML SECUR LOCK | ISTITUTO GIANNINA GASLINI | Inguinal Hernia | | | | |
2009-013687-39: Effets du système AnaConDa sur les paramètres respiratoires en ventilation mécanique spontanée avec aide inspiratoire: étude physiologique. |
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| Ongoing | 4 | 32 | Europe | SEVORANE, ULTIVA, SEVORANE, ULTIVA | CHU de Clermont-Ferrand | Paramètres respiratoires de patients de Réanimation sédatés intubés en ventilation mécanique spontanée avec aide inspiratoire, sortis du problème médical aigu et sans antécédents pulmonaires particuliers | | | | |
2009-011038-82: Postoperative pain after anesthesia: propofol vs. sevoflurane |
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| Ongoing | 4 | 244 | Europe | Diprivan PFS 1 % (500 mg/50 ml)-Fertigspritze, Sevorane-Inhalationsnarkotikum Konzentration 100ml | Medizinsche Universität Wien, Univ.Klinik f. Anästhesie u. Allgem. Intensivmedizin | postoperativ pain | | | | |
2014-001552-29: Determination of the minimal alveolar concentration of Sevoflurane in patient with end stage liver disease |
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| Ongoing | 4 | 48 | Europe | Sevoflurane, Sevoflurane Baxter, Sevoflurane Baxter | Medizinische Universität Wien, Abteilung für Anästhesie und allgemeine Intensivmedizin, Medizinische Universität Wien, Abteilung für Anästhesie und allgemeine Intensivmedizin | Orthotopic liver transplantation (OLT) is the only therapy for patients with liver failure. These patients have reduced anesthetic requirements compared with healthy patients. Sevoflurane has proven safe use for anesthesia during OLT. It has a known minimum alveolar concentration (MAC) in healthy adults ranging from 1.7 to 2.1%. However, the MAC of sevoflurane is unknown in patients liver failure The aim of this study was to determine the MAC of sevoflurane in patients undergoing OLT. | | | | |
2014-000678-20: Does isocapnic hyperventilation hasten early recovery with sevoflurane and desflurane in O2/air? |
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| Ongoing | 4 | 80 | Europe | SEVORANE Quick Fill 100%, Desfluraan, Sevoflurane, Suprane, Sevoflurane, Suprane | UZ Brussel, UZ Brussel | The absence of hypocapnia on the moment of emergence from general inhalatory anesthesia | | | | |
ChiCTR-IPR-16007818: The clinic research of of inhalational sevoflurane anesthesia induction on endotracheal intubation in pediatric patients with congenital heart disease |
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| Recruiting | 4 | 40 | | sevoflurane | Yantai Moutain Hospital; Yantai Moutain Hospital, selffinance | congenital heart disease | | | | |
| Not yet recruiting | 4 | 72 | | 0.2 ug/kgDexmedetomidine+ET 0.5 v/v% sevoflurane ;0.2 ug/kgDexmedetomidine+ET 1 v/v% sevoflurane ;0.2 ug/kgDexmedetomidine+ET 2 v/v% sevoflurane ;0.2 ug/kgDexmedetomidine+ET 4 v/v% sevoflurane ;0.4 ug/kgDexmedetomidine+ET 0.5 v/v% sevoflurane ;0.4 ug/kgDexmedetomidine+ET 1 v/v% sevoflurane ;0.4 ug/kgDexmedetomidine+ET 2 v/v% sevoflurane ;0.4 ug/kgDexmedetomidine+ET 4 v/v% sevoflurane ;0.8 ug/kgDexmedetomidine+ET 0.5 v/v% sevoflurane ;0.8 ug/kgDexmedetomidine+ET 1 v/v% sevoflurane ;0.8 ug/kgDexmedetomidine+ET 2 v/v% sevoflurane ;0.8 ug/kgDexmedetomidine+ET 4 v/v% sevoflurane | Department of Anesthesiology, Fuzhou General Hospital of Nanjing Military Region; Fuzhou General Hospital of Nanjing Military Region, Anesthesiology Research Foundation of B.Braun 2014 (BBDF-2014-009) | None | | | | |
ChiCTR-IPR-15006810: Effects of target - controlled infusion of sufentanil combined with sevoflurane general anesthesia on perioperative stress response |
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| Not yet recruiting | 4 | 40 | | Anesthesia is maintained with sufentanil TCI (at low concentration) and sevoflurane ;Anesthesia is maintained with sufentanil TCI (at common concentration) and sevoflurane | Department of Anesthesiology, Peking University Third Hospital; Peking University Third Hospital, Self-financing | General anesthesia of laparoscopic surgery | | | | |
ChiCTR-OPC-15007608: the Minium Alveolar Concentration (MAC)-awake of Sevoflurane in Patients with End-Stage Renal Disease |
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| Not yet recruiting | 4 | 60 | | to investigate the MAC-awake of sevoflurane in patients with normal renal function ;to investigate the MAC-awake of sevoflurane in patients with end-stage renal disease | the Second Affiliated Hospital of Anhui Medical University; the Second Affiliated Hospital of Anhui Medical University, the Scientific Funds of the Department of Anesthesiology | end-stage renal disease | | | | |
ChiCTR-IPR-15006583: The relationship between apolipoprotein E-Epsilon 4 polymorphism and postoperative cognitive dysfunction in old adults undergoing total intravenous anesthesia and sevoflurane anesthesia |
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| Not yet recruiting | 4 | 90 | | Anesthesia will be maintained with propofol target-controlled infusion. ;Anesthesia will be maintained with sevoflurane inhalation (end-tidal sevoflurane concentration between 1.5 MAC and 1.7MAC). ;Anesthesia will be maintained with propofol target-controlled infusion and sevoflurane inhalation (end-tidal sevoflurane concentration >=0.6 MAC). | Shenzhen People's Hospital; Shenzhen People's Hospital, Shenzhen science and technology innovation commission | postoperative cognitive dysfunction in old adults | | | | |
2016-003413-10: Assessment of the possible protective effect of anesthetics on the heart in patients undergoing cardiac surgery. Evaluación del posible efecto protector de los anestésicos halogenados sobre el corazón en los pacientes sometidos a cirugÃa cardiaca. |
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| Ongoing | 4 | 128 | Europe | SEVOFLURANE, PROPOFOL, Inhalation vapour, liquid, Emulsion for injection/infusion, SEVORANE, DIPRIVAN, PROPOFOL LIPOMED FRESENIUS | FIMABIS, FIMABIS | Cardiac surgery CirugÃa cardiaca, Cardiac surgery CirugÃa cardiaca, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2016-002197-13: IMPLICATION OF TWO ANESTHETIC TECHNIQUES TO REDUCE BLOOD LOSS IN CORRECTIVE JAW SURGERY. IMPLICACIÓN DE DOS TÉCNICAS ANESTÉSICAS PARA REDUCIR EL SANGRADO EN LA CIRUGÃA CORRECTIVA DE LA MANDÃBULA. |
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| Ongoing | 4 | 100 | Europe | SEVORANE, PROPOFOL, PROPOFOL, Inhalation vapour, liquid, Emulsion for injection/infusion, SEVORANE, PROPOFOL | Servicio de AnestesiologÃa y Reanimación, HOSPITAL UNIVERSITARIO LA PAZ | Assessment of the bleeding in ortognatic surgery. Evaluación del sangrado en cirugÃa ortognática., Assessment of the bleeding in corrective jaw surgery. Evaluación del sangrado en la cirugÃa correctiva de la mandÃbula., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR-IPR-16009318: Effects of butorphanol and fentanyl on emergence agitation after sevoflurane anesthesia in children: a randomized controlled trial |
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| Not yet recruiting | 4 | 120 | | butorphanol ;fentanyl | Mianyang Central Hospital, Sichuan.; Mianyang Central Hospital, self-financing | Strabismus | | | | |
ChiCTR-IIR-16008472: Effects of anesthesia on perioperative blood glucose level and postoperative complications |
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| Not yet recruiting | 4 | 90 | | Sevoflurane ;Isoflurane ;propofol ;Sevoflurane ;Isoflurane ;propofol | Department of anesthesia, the Second Affiliated Hospital, Harbin Medical University; The Second Affiliated Hospital, Harbin Medical University, self | diabetes | | | | |
2017-000098-35: COMPARATIVE STUDY OF NAUTICS AND VOMITING IN THREE ANESTHETICAL REGIMENS ESTUDIO COMPARATIVO DE NÁUSEAS Y VÓMITOS EN TRES REGÍMENES ANESTÉSICOS |
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| Ongoing | 4 | 90 | Europe | PROPOFOL, SEVOFLURANO, Solution for injection/infusion, Inhalation vapour, liquid, Propofol, SEVOFLURANE | SERVICIO DE ANESTESIOLOGÍA Y REANIMACIÓN HOSPITAL UNIVERSITARIO LA PAZ, SERVICIO DE ANESTESIOLOGÍA Y REANIMACIÓN HOSPITAL UNIVERSITARIO LA PAZ | Arthroscopy for Temporomandibular Artroscopia temporomaxilar, Arthroscopy for Temporomandibular Artroscopia temporomaxilar, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR-IPR-16009071: A Comparative study of Sevoflurane or Propofol combined with Sevoflurane induction for the Intubating Laryngeal Mask Airway insertion in Obese Patients |
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| Recruiting | 4 | 56 | | Sevoflurane induction ;Propofol combined with Sevoflurane induction | Beijing Friendship Hospital，Capital Medical University; Beijing Friendship Hospital，Capital Medical University, Self-financing | Intubating Laryngeal Mask Airway insertion among Obese Patients | | | | |
ChiCTR-IIR-17010964: Comparison of cardio-protective effects between sevoflurane and propofol based total intravenous anaesthesia in patients after cardiac surgery |
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| Recruiting | 4 | 120 | | Sevoflurane anesthesia ;propofol anesthesia | Xinqiao Hospital, Third Military Medical University; Xinqiao Hospital, National Natural Science Foundation of China (Grant No. 81070094 and No. 81571870) | Cardiac injury | | | | |
ChiCTR-IPD-17011558: Determination of free hexafluoro-2 propanol (HFIP) in adults' blood after different concentration of sevoflurane anesthesia |
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| Recruiting | 4 | 39 | | using different sevoflurane concentrations: 0.5MAC, 1.0MAC, 1.5MAC, for anesthesia | North Sichuan Medical College; North Sichuan Medical College, North Sichuan Medical College | laparoscopic gastrointestinal disease | | | | |
2017-003225-15: Comparison between sedation obtained with Sevoflurane administered through inhalation and Propofol administered through intravenous infusion Confronto tra sedazione con Sevoflurane somministrato per via inalatoria vs Propofol somministrato per via endovenosa |
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| Not yet recruiting | 4 | 40 | Europe | Sevoflurano, Propofol, N01AB08, N01AX10, Pressurised inhalation, solution, Solution for injection, SEVOFLURANE PIRAMAL - 100% V/V LIQUIDO PER INALAZIONE 1 FLACONE IN VETRO DA 250 ML, PROPOFOL KABI - 20MG/ML EMULSIONE INIETTABILE O PER INFUSIONE 10 FLACONCINI DA 50 ML | AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI, Pall International | Preoperative-scheduled sedation in surgical patients admitted in the Intensive Care Unit (ICU) for postoperative monitoring Sedazione, prevista nel preoperatorio, di pazienti chirurgici ricoverati in Unità di Terapia Intensiva (UTI) per il monitoraggio postoperatorio, Postoperative sedation in patients with indication to ICU admission. Sedazione postoperatoria in pazienti con indicazione al ricovero in UTI., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR-IPR-17010381: Surgical pleth index-guided remifentanil administration during functional endoscopic sinus surgery under sevoflurane anesthesia |
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| Not yet recruiting | 4 | 80 | | Surgical pleth index-guided remifentanil analgesia ;conventional remifentanil analgesia | The Second Affiliated Hospital of Nantong University; The Second Affiliated Hospital of Nantong University, Research Fund | functional endoscopic sinus surgery | | | | |
ChiCTR-IPR-16008113: Effect of Intraoperative Dexmedetomidine Infusion Combined with Sevoflurane during BIS-guided Fast Track Anesthesia for Intracranial Aneurysms Interventional Surgery |
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| Not yet recruiting | 4 | 60 | | receive DEX (40μg/ml) 0.6μg/kg for 10 min, then change into 0.4μg/kg/h | Southern District of Anhui Provincial Hospital; Southern District of Anhui Provincial Hospital, Southern District of Anhui Provincial Hospital | Intracranial aneurysm | | | | |
ChiCTR-IPD-17011615: Effect of buccal dexmedetomidine premedication on minimum alveolar concentration of sevoflurane for successful insertion of laryngeal mask airway in children |
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| Recruiting | 4 | 70 | | buccal dexmedetomidine 2μg/kg ;buccal dexmedetomidine 4μg/kg | Longguang Distict People's Hospital of Shenzhen; Longguang Distict People's Hospital of Shenzhen, Shenzhen Science and Technology Project | laparoscopic inguinal herniorhaphy or Penile plastic Surgery | | | | |
ChiCTR-OIh-17011790: Appropriate does of dexmedetomidine for the prevention of emergence agitation after sevoflurane anaesthesia for tonsillectomy and(or)adenoidectomy sugery in pediatric |
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| Not yet recruiting | 4 | 50 | | dexmedetomidine | The Second Affiliated Hospital of Harbin Medical University; Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University, self | Tonsil and Adenoid hypertrophy | | | | |
| Not yet recruiting | 4 | 32 | | sevoflurane | First Affiliated Hospital of Anhui Medical University; First Affiliated Hospital of Anhui Medical University, the Scientific Funds of the Department of Anesthesiology | sleep disorder | | | | |
ChiCTR1800015526: the effect of sevoflurane or propofol on neoatal Apagar score and BSI in caesarean section undergoing general anesthesia |
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| Not yet recruiting | 4 | 100 | | Obstetric general anesthesia ;Obstetric general anesthesia | Tianjin Central Hospital of Gynecology and Obstetrics; Tianjin Central Hospital of Gynecology and Obstetrics, Department of Anesthesiology, Tianjin Central Hospital of gynecology and obstetrics | Obstetric general anesthesia | | | | |
ChiCTR-OPD-17013632: Comparison of different doses of intravenous dexmedetomidine for premedication in children undergoing tonsillectomy and adenotonsillectomy |
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| Recruiting | 4 | 75 | | 0.5ug /kg intravenous dexmedetomidine for premedication ;1.0 ug /kg intravenous dexmedetomidine for premedication ;2.0 ug/kg intravenous dexmedetomidine for premedication | The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University; The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Public Welfare Science and Technology Project | sevoflurane anesthesia for pediatric tonsillectomy | | | | |
ChiCTR1800018344: Effects of Low-dose Ketamine on MACBAR of Sevoflurane in Laparoscopic Cholecystectomy Surgery |
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| Recruiting | 4 | 100 | | ketamine 5ug·kg/min ;ketamine 10ug·kg/min ;ketamine 20ug·kg/min ;ketamine 0ug·kg/min | Affiliated Hospital of North Sichuan Medical College; Affiliated Hospital of North Sichuan Medical College, reseach funding for postgraduate | Laparoscopic Cholecystectomy Surgery | | | | |
ChiCTR1800019026: Effects of different concentrations of target control remifentanil on sevoflurane MACBAR in patients undergoing b-grade liver function laparoscopic surgery |
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| Not yet recruiting | 4 | 75 | | Normal liver function (remifentanil 0ng/ml) ;Grade B liver function (remifentanil 0ng/ml) ;Grade B liver function (remifentanil 1ng/ml) | Affiliated Hospital of North Sichuan Medical College; None, reseach funding for postgraduate | Patients with grade B liver function | | | | |
ChiCTR1900022050: Effects of propofol and sevoflurane on T cell immune function and Th cell differentiation in children with SMPP undergoing fiberbronchoscopy: a randomized controlled trial |
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| Not yet recruiting | 4 | 60 | | Induced by inhalation of 8% sevoflurane and remifentanil 1 μ g kg-1, 2 ~ 5% sevoflurane (BIS to 40 μ g) was inhaled during operation, and remifentanil (1 μ g kg- 1 ·min-1) was continuously infused to maintain anesthesia ;Induced by remifentanil (1 μ g/ kg-1 and propofol 2 -4 mg /kg-1 , and infusion of propofol (9 /-15 mg/ kg- 1 ·h-1) and remifentanil( 1 μ g/ kg-1) to maintain anesthesia with BIS between 40 and 50 | Maternal and Child Health Hospital of Hubei Province; Maternal and Child Health Hospital of Hubei Province, Unit self-financing | Severe mycoplasma pneumonia | | | | |
2019-000171-16: Comparison of the differences in the outcomes of patients receiving two different types of anaesthetics during heart surgery. |
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| Not yet recruiting | 4 | 50 | Europe | Desflurane, Isoflurane, Sevoflurane, Propofol, Inhalation vapour, liquid, Emulsion for injection/infusion, Desflurane, Isoflurane, Sevoflurane, Diprivan | King's College Hospital NHS Foundation Trust, National Institute for Academic Anaesthesia | Cardiopulmonary bypass (CPB) and revascularisation-induced ischaemic reperfusion injury, Complications following Cardiopulmonary bypass (CPB) surgery, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR1800017009: The combined use of sevoflurane and nalbuphine hydrochloride for for chidren undergoing enteroscopy |
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| Recruiting | 4 | 100 | | injected with naborphine 0.2mg/kg 5 minutes before anesthesia ;injected with normal saline 10ml before anesthesia | Guangzhou Women and Children Medical Center; Guangzhou women and children medical center, National Natural Science Foundation of China | Pediatric enteroscopy | | | | |
ChiCTR1800019106: Effects of different sedation drugs on postoperative lung function of patients undergoing crdiopulmonry bypss heart surgery and its relationship with glycocalyx |
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| Recruiting | 4 | 40 | | sevoflurane ;propofol | The Affiliated Hospital of Guizhou Medical University; The Affiliated Hospital of Guizhou Medical University, self-financing | acute lung injury | | | | |
ChiCTR1800019481: Effects of different sedation drugs on postoperative renal function of patients undergoing crdiopulmonry bypss heart surgery and its relationship with glycocalyx |
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| Recruiting | 4 | 60 | | sevoflurane ;propofol | The Affiliated Hospital of Guizhou Medical University; The Affiliated Hospital of Guizhou Medical University, Self-funding | acute kidney injury | | | | |
ChiCTR1800019773: Effects of different anesthesia methods on oxidative stress response in postoperative brain function in patients undergoing valve replacement |
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| Recruiting | 4 | 60 | | sevoflurane ;propofol | Affiliated Hospital of Guizhou Medical University; Affiliated Hospital of Guizhou Medical University, Self-raising | Heart valve patient | | | | |
ChiCTR-IPR-17011915: The influence of volatile induction and maintenance anesthesia with sevoflurane and desflurane on postoperative agitation, delirium and cognitive disorder in pediatric anesthesia |
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| Not yet recruiting | 4 | 1000 | | volatile induction and maintenance anesthesia(VIMA) with sevoflurane ;desflurane anesthesia after sevoflurane inhaled induction ;propofol intravenous maintenance after sevoflurane inhaled induction ;total intravenous anesthesia?(TIVA) with propofol ;desflurane inhaled maintenance after propofol induction | The First Affiliated Hospital, University of South China; The First Affiliated Hospital, University of South China, Hunan science technology and innovation fundation | paediatric postoperative cognitive disorder | | | | |
ChiCTR1900022281: Effect of different doses of dexmedetomidine on sevoflurane MAC in adult laryngeal mask placement |
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| Not yet recruiting | 4 | 100 | | Sevoflurane induction (dexmedetomidine 0μg/kg) ;Sevoflurane induction (dexmedetomidine 0.5μg/kg) ;Sevoflurane induction (dexmedetomidine 1μg/kg) ;Sevoflurane induction (dexmedetomidine 1.5μg/kg) | affiliated hospital of North Sichuan Medical College; Affiliated Hospital of North Sichuan Medical College, Graduate research funding | Gallstone | | | | |
ChiCTR1900023034: Effects of different anesthetics on the function of plasma exosomes in patients undergoing radical gastrectom |
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| Not yet recruiting | 4 | 60 | | propofol ;sevoflurane | Harbin Medical University Cancer Hospital; Harbin Medical University Cancer Hospital, Funding for postdoctoral projects | gastric cancer | | | | |
ChiCTR1900024115: Effects of sevoflurane combined with dexmedetomidine sedation on postoperative delirium and outcome in elderly patients undergoing hip replacement--A clinical multicenter randomized controlled trial |
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| Not yet recruiting | 4 | 895 | | Dexmedetomidine and Sevoflurane ;Sevoflurane | The second Affiliated Hospital of Anhui Medical University; The Second Affiliated Hospital of Anhui Medical University, self-financing | femoral neck fracture | | | | |
ChiCTR1900026098: Comparison of two anesthesia methods in children undergoing fiberoptic bronchoscopy through laryngeal mask |
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| Not yet recruiting | 4 | 60 | | Remifentanil 0.3-0.5μg/kg.min ;4%-6% sevoflurane | WenZhou Medical University Affiliated Second Clinical Hospital; WenZhou Medical University Affiliated Second Clinical Hospital, Fund from tutor | Pediatric pneumonia | | | | |
ChiCTR1900027234: Effect of propofol on the reaction time of rocuronium compared with desflurane and sevoflurane |
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| Not yet recruiting | 4 | 120 | | Monitoring of muscle relaxation during desflurane inhalation anesthesia ;Monitoring of muscle relaxation during sevoflurane inhalation anesthesia ;Monitoring of muscle relaxation during intravenous anesthesia with propofol | Beijing Chaoyang Hospital, Capital Medical University; Beijing Chaoyang Hospital, Capital Medical University, none | Effects of inhalation anesthesia on muscle relaxation | | | | |
ChiCTR1900026872: The effect of different doses of dexmedetomidine on anesthesia depth monitoring in children |
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| Not yet recruiting | 4 | 120 | | No use of dexmedetomidine ;IV 0.25 μ g / kg dexmedetomidine ;IV 0.5 μ g / kg dexmedetomidine ;IV 0.75 μ g / kg dexmedetomidine | Hunan Children's Hosptal; Hunan Children's Hosptal, Supported by Hunan Youth Natural Science Foundation | Concealed penis and hypospadias | | | | |
ChiCTR1800014571: Effects of expression of inflammatory cytokines and heat shock protein 70 on sevoflurane for preeclampsia maternal |
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| Not yet recruiting | 4 | 80 | | none ;sevoflurance ;none ;sevoflurance | Guangdong Women and Children Hospital; Guangdong Women and Children Hospital, Project funding | preeclampsia | | | | |
ChiCTR1900025320: Effects of total propofol or remifentanil anesthesia during 30 min before end of operation on the extubation parameters of patients undergoing radical mastectomy |
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| Recruiting | 4 | 100 | | total propofol anesthesia ;total sevoflurane anesthesia | The First Affiliated Hospital of Nanjing Medcial University; The First Affiliated Hospital of Nanjing Medcial University, self fund | radical mastectomy | | | | |
ChiCTR2000035959: Effect of ephedrine and phenylephrine on sublingual microcirculation in elderly patients undergoing laparoscopic rectal cancer |
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| Recruiting | 4 | 100 | | Sufentanil 0.5 μg/kg + propofol 1.5-2 mg/kg + cis-atracuramide 0.15 mg/kg was used for anesthesia induction, and sevoflurane (0.7-1.3 MAC) + remifentanil (0.05- 0.2 μg/kg/min) + cis-atracuramide (0.1 mg/kg/h) for maintenance. During the induction and maintenance period, the average arterial pressure was lower than 65mmHg.& ;Sufentanil 0.5 μg/kg + propofol 1.5-2 mg/kg + cis-atracuramide 0.15 mg/kg was used for induction of anesthesia, mean arterial pressure was lower than 65 mmHg during induction and maintenance, and sevoflurane (0.7- 1.3MAC) + remifentanil (0.05-0.2 μg/kg/min) + cis-atracuramide (0.1mg/kg/h) for maintenance. During the induct | First Affiliated Hospital of Soochow University; Fisrt Affliated Hospital of Soochow University, Department Research Fund | Perioperative hypotension | | | | |
ChiCTR2000029843: Effects of sevoflurane inhalation at different concentrations and at different times on intraoperative electrophysiological monitoring in patients with facial spasm |
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| Recruiting | 4 | 80 | | Sevoflurane 0.5MAC ;Sevoflurane0.75MAC ;Sevoflurane1MAC ;TIVA | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital; Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, Sichuan provincial health and family planning commission | facial spasm | | | | |
2020-003903-32: Comparing spinal anesthesia and general anesthesia in patients with ankle fracture Spinaalipuudutuksen ja yleisanestesian vertailu nilkkamurtumapotilailla |
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| Ongoing | 4 | 110 | Europe | Concentrate for solution for injection, Suspension for injection, Solution for injection, Inhalation vapour, Tablet, Capsule, Bicain pond spinal, Fentanyl, Profast, ROCURONIUM FRESENIUS KABI, Sevorane, Para-Tabs, Omeprazol ratiopharm, Targiniq, Oxynorm | University of Oulu, University of Oulu | Ankle fracture needing surgical fixation Kirurgisesti hoidettava nilkkamurtuma, Ankle fracture which needs to be surgically operated Leikkausta vaativa nilkkamurtuma, Diseases [C] - Injuries, poisonings, and occupational diseases [C21] | | | | |
ChiCTR2000031812: Effect of hydroxycodone on half effective concentration of sevoflurane inhibiting laryngeal mask implantation in children |
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| Not yet recruiting | 4 | 40 | | oxycodone 0.1mg/kg | Taizhou Hospital of Zhejiang Province; Taizhou Hospital of Zhejiang Province, Course funding | inguinal hernia | | | | |
| Recruiting | 4 | 60 | Europe | Propofol, Sevoflurane | Algemeen Ziekenhuis Maria Middelares | Sinus Infection Chronic | 03/21 | 03/21 | | |
ChiCTR2000040952: Effect of rocuronium on the median effective time (ET50) of sevoflurane to reduce cardiovascular responses to endotracheal intubation |
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| Recruiting | 4 | 54 | | rocuronium.; normal saline (NS) | The First College of Clinical Medical Science, China Three Gorges University, Yichang, China; The First College of Clinical Medical Science, China Three Gorges University, self-raised | the patients requirement of general anesthesia | | | | |
ChiCTR1900022899: Effects of salbutamol aerosol on sevoflurane pharmarcodynamics and incidence of early postoperative pulmonary complications in patient with chronic pulmonary obstructive disease |
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| Not yet recruiting | 4 | 60 | | salbutamol aerosol ;blank control reagent | Shaoxing People's Hospital; Shaoxing People's Hospital, Sponsored by municipal public welfare funding | chronic obstructive pulmonary disease | | | | |
| Completed | 4 | 50 | | femoral nerve block before anesthesia ;nothing | The Second Affiliated Hospital of North Sichuan Medical College; The Second Affiliated Hospital of North Sichuan Medical College, Nanchong Science and Technology Project(18SXHZ0161) | Patients with knee disease who will undergo unilateral knee arthroscopy | | | | |
2018-001252-35: Changes in the human brain induced by general anaesthesia Forandringer i hjernen efter generel anæstesi |
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| Not yet recruiting | 4 | 30 | Europe | Propofol, Inhalation vapour, liquid, Emulsion for injection/infusion, Sevorane, sevoflurane, Propofol | Kirsten Møller, Rigshospitalet | This trial investigates the effects of general anaesthesia on the helathy human brain. Thus, only healthy, young adults with no medical conditions will participate as volunteers in this study. Dette forsøg involverer kun raske, frivillige, voksne forsøgspersoner., This trial only involves healthy, young adults, that volunteer to participate. Dette forsøg involverer kun raske, frivillige, voksne forsøgspersoner., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
