sevoflurane / Generic mfg. 
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  • ||||||||||  ketamine / Generic mfg., sevoflurane / Generic mfg., dexmedetomidine / Generic mfg.
    "Opioid-Free Anesthesia and Erector Spinae Plane Block as an Anesthetic Technique for Percutaneous Nephrolithotomy." (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4732;    
    This strategy can be an option in patients where reducing opioid adverse effects is desired, and as an alternative in case of drug shortages. These two patients undergoing surgery under this technique open the door to consider that opioids are not essential, as long as multimodal analgesic techniques are utilized.
  • ||||||||||  sevoflurane / Generic mfg.
    Craniotomy and EDAS in a Patient with Moya Moya Disease (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4718;    
    Maintenance anesthesia commenced utilizing sevoflurane...The patient had an uneventful recovery and was discharged on postoperative day four. This paper will discuss the anesthetic management and role of intraoperative neuromonitoring in the EDAS procedure.
  • ||||||||||  Bridion (sugammadex) / Merck (MSD)
    Innovative Approach:  (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4621;    
    The surgery lasted 9 hours, and she was extubated in the OR after the neuromuscular blockade was reversed with sugammadex...However, the use of robotic surgery resulted in less postoperative pain and an early discharge (24 hours). RS are typically utilized for intra-abdominal procedures, but in this instance, the new approach allowed for better outcome and pain management for this patient.
  • ||||||||||  sevoflurane / Generic mfg.
    Recurrent Life-Threatening Oxygen Embolus During Surgical Treatment of Perirectal Abcess (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4425;    
    Each of these events were preceded by injection of 3% hydrogen peroxide solution in the surgical field to identify the internal opening of the fistula tract. This physiologic signature of pulmonary embolism is consistent with venous embolization of oxygen generated by intraoperative injection of hydrogen peroxide.
  • ||||||||||  fentanyl citrate / Generic mfg., sevoflurane / Generic mfg., rocuronium / Generic mfg.
    Mediastinal Impalement of a Metallic Foreign Body in a 5 Year Old Child (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4416;    
    Anesthesia was maintained with sevoflurane...The procedure was converted to VATS. Key considerations as a pediatric anesthesiologist included meticulous airway management, vigilant hemodynamic monitoring, and multiple reassessments, as happened once the object was discovered as intrathoracic.
  • ||||||||||  dobutamine / Generic mfg.
    Cauda Equina Syndrome after Inadvertent Intrathecal Dobutamine Injection (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4039;    
    Electrophysiological examination revealed evidence of dysfunctional continuity in the dorsal column, and MRI finding showed nonspecific myelitis. Two years later, those symptoms gradually improved
  • ||||||||||  Seizalam (midazolam intramuscular) / Pfizer
     (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_4028;    
    The need for offsite anesthesia and MRI compatible equipment presented challenges. We discuss a unique strategy for anesthetic management for a patient with MD requiring anesthesia outside of the operating room setting.
  • ||||||||||  Bridion (sugammadex) / Merck (MSD)
    Bronchospasm After Sugammadex Administration: A Case Report (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_3942;    
    Treatment included albuterol, propofol, dexmedetomidine, and supportive care. This case contributes to the literature by providing evidence for other patient demographics who may be at risk for sugammadex-induced bronchospasm.
  • ||||||||||  remifentanil / Generic mfg., sevoflurane / Generic mfg.
    Anesthetic Management of an Adult Patient with Propionic Acidemia undergoing Parathyroidectomy (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_3722;    
    We performed a volatile-heavy induction, administered nutritional supplementation intraoperatively, and utilized sevoflurane with remifentanil to avoid excessive physiologic stress and production of undesired byproducts. The patient had a metabolically stable perioperative course without clinical or laboratory evidence of ketoacidosis.
  • ||||||||||  sevoflurane / Generic mfg.
    Unexpected episodes of unresponsiveness in the PACU (Exhibit Hall) -  Aug 6, 2024 - Abstract #ASA2024ASA_3540;    
    The patient received propofol, sevoflurane, and required two doses of succinylcholine...Patient remained hemodynamically stable throughout and endorsed awareness during both episodes despite losing ability to communicate or breathe. The IV tubing and the fluid bag were replaced after the onset of the second episode with no further complications, supporting the hypothesis that residual succinylcholine remained in the IV tubing.
  • ||||||||||  dobutamine / Generic mfg.
    Journal:  Perioperative dobutamine infusion in an African lion (Panthera leo). (Pubmed Central) -  Aug 4, 2024   
    The IV tubing and the fluid bag were replaced after the onset of the second episode with no further complications, supporting the hypothesis that residual succinylcholine remained in the IV tubing. The lion was immobilized via intramuscular darts containing midazolam (0.033 mg/kg), medetomidine (50
  • ||||||||||  sevoflurane / Generic mfg., isoflurane / Generic mfg.
    Journal:  Inhalational anaesthetic agent consumption within a multidisciplinary veterinary teaching hospital: an environmental audit. (Pubmed Central) -  Aug 3, 2024   
    Comparison to human anaesthesia settings showed comparable consumption rates to small animals, suggesting shared environmental implications, albeit on a smaller scale. This research highlights the importance of continued evaluation of veterinary anaesthesia practices to balance patient safety with environmental stewardship; potential mitigation strategies are explored and discussed.
  • ||||||||||  sevoflurane / Generic mfg.
    Journal:  ADAR1 prevents ZBP1-dependent PANoptosis via A-to-I RNA editing in developmental sevoflurane neurotoxicity. (Pubmed Central) -  Jul 31, 2024   
    Taken together, these results illustrate that ADAR1-P150 exhibits a prominent role in preventing ZBP1-dependent PANoptosis through A-to-I RNA editing in developmental sevoflurane neurotoxicity. Application of engineered cadRNAs to rectify the compromised ADAR1-dependent A-to-I RNA editing provides an inspiring direction for possible clinical preventions and therapeutics.
  • ||||||||||  sevoflurane / Generic mfg.
    Journal, IO biomarker:  Molecular Mechanism of Sevoflurane Affecting Fetal Nervous System's Development Through the GABAAR/Sirt 1 Pathway. (Pubmed Central) -  Jul 30, 2024   
    Compared with the control group, the 3 h sevoflurane group and the 6 h sevoflurane group neurons were arranged sparsely, the cells appeared to be swollen, the evasion latency, the apoptosis rate of neurons, the expression of Caspase-3, and BAX increased significantly, and the number of crossing the plateau, the level of 5-HT and Ach in the brain tissues, and the expression of GABAAR, Sirt-1, and BCL-2 were decreased significantly, and the differences existed between the groups (P < .5); compared with the 6 h sevoflurane group, neuronal morphological changes in the hippocampal tissue of the 6 h sevoflurane+SRT1720 group were improved, with a significant decrease in the evasion latency, neuronal apoptosis rate, expression of Caspase-3 and BAX, and a significant increase in the number of traversing platforms, brain tissue 5-HT, Ach level, GABAAR, Sirt-1, and BCL-2 expression (P < .5); compared with the SRT1720 group, the neurons in the 6 h sevoflurane + SRT1720 group were sparsely arranged, with a significant increase in evasion latency, neuronal apoptosis rate, caspase-3, BAX expression, and a significant decrease in the number of traversing platforms, brain tissue 5-HT, Ach level, GABAAR, Sirt-1, and BCL-2 expression (P < .5 ). Sevoflurane can affect the neurological development of rat offspring, which may be related to the inhibition of Sirt-1 expression.
  • ||||||||||  sevoflurane / Generic mfg.
    Review, Journal:  Sevoflurane: an opportunity for stroke treatment. (Pubmed Central) -  Jul 29, 2024   
    We believe that the role of sevoflurane in stroke may be a key area for future research. Therefore, this review mainly summarizes the relevant mechanisms of sevoflurane preconditioning and postconditioning in stroke in the past 20 years, revealing the bright prospects of sevoflurane in stroke treatment.
  • ||||||||||  sevoflurane / Generic mfg.
    Review, Journal:  Balancing Patient Needs With Environmental Impacts for Best Practices in General Anesthesia: Narrative Review and Clinical Perspective. (Pubmed Central) -  Jul 28, 2024   
    Other LCA gaps included a lack of comprehensive GHG emission estimates related to the manufacturing of TIVA plastic components, high-temperature incineration of propofol, and gas capture technologies for inhaled anesthetics. Considering that scarce LCA evidence does not allow for a definite conclusion to be drawn regarding the overall environmental impacts of sevoflurane and TIVA, we conclude that current anesthetic practice involving these agents should focus on patient needs and established best practices as more LCA research is accumulated.
  • ||||||||||  sevoflurane / Generic mfg.
    Journal:  System leaks and the loss of sevoflurane. (Pubmed Central) -  Jul 23, 2024   
    When a decrease in the Tce-MEPs amplitude is detected, the cause of the decrease in the MEPs amplitude can be indirectly determined by whether the decrease is bilateral. No abstract available
  • ||||||||||  sevoflurane / Generic mfg.
    SUSTAINABLE SURGERY - QUANTIFYING THE CARBON FOOTPRINT OF A LAPAROSCOPIC CHOLECYSTECTOMY: A LIFE-CYCLE ASSESSMENT STUDY (CO2SURG-STUDY) (Poster Stage 4) -  Jul 18, 2024 - Abstract #UEGW2024UEGW_2492;    
    A substantial reduction in the carbon footprint can be achieved by replacing disposable surgical instruments (trocars and clipper) with reusable alternatives, reducing surgical drapes, switching to total intravenous anaesthesia, and transitioning to 100% green energy. The results of this study extend beyond LC and can be used to accelerate and provide guidance for sustainability initiatives, an essential step towards sustainable surgical care.Moreover, the most impactful approach to reduce the carbon footprint lies in avoiding unnecessary procedures.
  • ||||||||||  sevoflurane / Generic mfg., dexmedetomidine / Generic mfg.
    Enrollment change, Trial termination:  Anesthesia in Patients With Mitochondrial Disease (clinicaltrials.gov) -  Jul 16, 2024   
    P=N/A,  N=19, Terminated, 
    Yet, it had no effect on post-operative pulmonary function. N=60 --> 19 | Unknown status --> Terminated; due to covid-19 we were not on track with enrollment rate
  • ||||||||||  sevoflurane / Generic mfg.
    Preclinical, Journal:  Substantia Innominata Glutamatergic Neurons Modulate Sevoflurane Anesthesia in Male Mice. (Pubmed Central) -  Jul 15, 2024   
    Not yet recruiting --> Recruiting Our study shows that SI glutamatergic neuronal activity facilitates emergence from sevoflurane anesthesia and provides evidence for the involvement of the SI-LH glutamatergic pathway in the regulation of consciousness during GA.
  • ||||||||||  sevoflurane / Generic mfg.
    Journal, Surgery:  Efficiency of CONTRAfluran (Pubmed Central) -  Jul 14, 2024   
    Over half of the sevoflurane administered was not captured by the CONTRAfluran canister when minimal flow techniques were used, likely due to residual accumulation of sevoflurane in the patient after tracheal extubation or, to a lesser extent, due to ventilation system leakage. However, as every prevented emission is commendable, CONTRAfluran may be a potentially valuable tool for reducing the environmental footprint of sevoflurane-based anaesthesia.
  • ||||||||||  Journal:  The Ventilatory Changes of Pediatric Peroral Endoscopic Myotomy Patients. (Pubmed Central) -  Jul 12, 2024   
    Anaesthesia maintenance was provided with 0.8-1.2 minimum alveolar concentration sevoflurane in a 40-60% O2-air mixture, Remifentanil infusion and bolus doses of Rocuronium...Postoperative pain management is provided with paracetamol and tramadol in total 8 patients (50%)...Beside the known anaesthetic management strategies, a tailored approach should be adopted for each patient. Further investigations should be conducted to develop standardized management.