- |||||||||| Can Lactated Ringer Alone Cause Severe Hyperkalemia? (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_4003;
General anesthesia involved fentanyl, propofol and rocuronium with sevoflurane maintenance...Hyperkalemia was treated with calcium, insulin, dextrose, Albuterol, hyperventilation. We explore multiple potential causes for the hyperkalemia, including 5 MEq K in 1.3 liters LR, the Tacrolimus, Bactrim, and status as a diabetic renal transplant patient with concomitant renal injury.
- |||||||||| Aorto-enteric Fistula Repair In Unstable Pediatric Patient (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_4000;
He lost over 4 liters of blood and underwent MTP with 12 pRBC, 12 FFP, 2 units of platelets, 1 unit of pooled cryoprecipitate, and 1500 cc crystalloid. He was brought to PICU intubated, extubated POD 2, and discharged home POD 15.
- |||||||||| sevoflurane / Generic mfg.
Protecting The Powerhouse Of The Cell: Anesthesia Considerations For Twnk-associated Mitochondrial Disease (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_3942;
The TWNK gene encodes a DNA helicase responsible for the production and maintenance of mitochondrial DNA. In order to optimize anesthetic care for this patient, we avoided metabolic disturbances, considered possible underlying myopathy, and utilized anesthetics with minimal impact on mitochondrial function based on collaborative pre-operative discussion with genetics and ophthalmology.
- |||||||||| sevoflurane / Generic mfg.
Managing A Jehovah's Witness Patient During Trauma With Major Blood Loss (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_3936;
The patient was managed with a pre-induction arterial line, general anesthesia with sevoflurane and nitric oxide and transesophageal echocardiography...She required high dose vasopressors, but blood loss was contained early. She was admitted to the intensive case unit and weaned off vasopressors and extubated.
- |||||||||| sevoflurane / Generic mfg.
Sevoflurane Tec 7 Vaporizer Output As A Function Of Fresh Gas Flow Rate (Virtual - Mobile App) - Aug 15, 2022 - Abstract #ASA2022ASA_3575;
As FGF increases >5 L/min, the vaporizer progressively delivers less sevoflurane compared to the dial setting. FGF >5 L/min during anesthetic induction leads to diminished anesthetic concentration delivered and unnecessary anesthetic waste.
- |||||||||| sevoflurane / Generic mfg.
Management Of Severe Pediatrics OSA (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_3459;
After preoxygenation , she underwent inhalational induction with sevoflurane...Attempts to perform nasal endoscopy was aborted and patient was immediately intubated for tonsilloadenoidectomy. Post procedure, she was extubated to BiPAP.
- |||||||||| The Performance Of Opioid Free Anesthesia In Beriatric Surgery (Virtual - Mobile App) - Aug 15, 2022 - Abstract #ASA2022ASA_3121;
In the 48 hours following surgery, the patients in the OFA cohort exhibited significantly less postoperative pain compared to the patients in the OBA cohort. The mean VAS after 48 hours was 2,5 in the OFA group and 3,7 in the OBA group, respectively.
- |||||||||| sevoflurane / Generic mfg.
Sevoflurane-induced Cognitive Impairment In Young Mice Is Dependent On The Generation Of Tau-ps262 (Virtual - Mobile App) - Aug 15, 2022 - Abstract #ASA2022ASA_3108;
The first exposure of sevoflurane in young mice induced Tau phosphorylation at serine 262 (Tau-PS262), leading to Tau release from the microtubule. The second and third exposure of sevoflurane in young mice then acted on the released Tau to induce Tau phosphorylation at serine 202 and threonine at 205 (Tau-PS262/PT205), leading to cognitive impairment in the mice.
- |||||||||| sevoflurane / Generic mfg.
Intergenerational Effects of Surgery and Sevoflurane Anesthesia in Young Adult Rats with Traumatic Brain Injury (Room 243) - Aug 15, 2022 - Abstract #ASA2022ASA_3014;
The second and third exposure of sevoflurane in young mice then acted on the released Tau to induce Tau phosphorylation at serine 202 and threonine at 205 (Tau-PS262/PT205), leading to cognitive impairment in the mice. These findings provide experimental early evidence of intergenerational PND in a rodent model of TBI + SEVO and surgery + SEVO in young adult males.
- |||||||||| sevoflurane / Generic mfg.
Volatile Anesthetic Loading of the Sonoparticles; A Preparation for Future Clinical Applications (Room 243) - Aug 15, 2022 - Abstract #ASA2022ASA_3013;
Our objective is to load sevoflurane in a lipid microsphere perflutren sonoparticles as a vehicle and demonstrate its release in response to externally delivered sound shock waves...Conclusion : Ultrasonic contrast media offer a reliable vehicle that may be used to deliver volatile anesthetics to biological systems for their immunomodulating or preconditioning properties. Direct visualization of these materials in any internal organ allows us to locally release volatile anesthetic agents on demand by applying ultrasonic waves with a higher mechanical impact.
- |||||||||| sevoflurane / Generic mfg.
Irreversible Ischemic Brain Injury From Prolonged Moderate Hypotension (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2959;
This case report describes a healthy 22-year-old female who received general anesthesia with sevoflurane maintenance for nasal septal reconstruction followed by bilateral breast augmentation...The patient was terminally extubated on POD7. The importance of blood pressure management, recognition of the inadequacy of cerebral autoregulation, and awareness of individual variability are of critical importance to prevent cerebral ischemia.
- |||||||||| sevoflurane / Generic mfg., midazolam hydrochloride / Generic mfg., labetalol / Generic mfg.
Is This Really A Seizure Under General Anesthesia? (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2901;
Seizure was stopped with midazolam. No other precipitating factors, intraoperative seizure in the patient was deemed ecclamptic in nature.
- |||||||||| sevoflurane / Generic mfg.
Anesthetic Complications In A Patient With Diagnosed Costello Syndrome (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2846;
The patient was induced with Sevoflurane and noted to have secretions with decreasing oxygen saturations...Patients with Costello Syndrome can have difficult airways with potential for difficult ventilation. There is limited published data on these patients having reactive airways with risk for laryngospasm.
- |||||||||| sevoflurane / Generic mfg.
Complex Extraction Of Tracheal Stent In A Patient With Severe Tracheal Stenosis. (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2845;
Mask ventilation was confirmed followed by direct laryngoscopy with serial balloon dilations for ETT placement and upsizing. Multiple cycles of extubation, direct laryngoscopy under apnea, and re-intubation were needed to remove the stent, which was identified as a non-retrievable palliative stent intended for patients with a life expectancy of less than 6 months.
- |||||||||| sevoflurane / Generic mfg.
Effect Of Sevoflurane On The Proliferation Of A549 Lung Cancer Cells (Virtual - Mobile App) - Aug 15, 2022 - Abstract #ASA2022ASA_2684;
However, the in vivo data showed no correlation between sevoflurane exposure and A549 cell proliferation. Thus, further research is required to understand fully the effects of sevoflurane on cancer progression and to reconcile differences between the in vitro and in vivo experimental results.
- |||||||||| Adrenalectomy In A Patient With Pheochromocytoma And Parkinson’S Disease (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2518;
General anesthesia was maintained with sevoflurane, dexmedetomidine and remifentanil, and required boluses of esmolol, nitroglycerine, and phentolamine (6 doses)...Post-operatively she remained off vasopressors and remained hemodynamically stable. Levodopa/carbidopa were resumed immediately postoperatively.
- |||||||||| sevoflurane / Generic mfg., esmolol / Generic mfg., rocuronium / Generic mfg.
Anesthesia For A Pediatric Patient With Aicardi-goutieres Syndrome (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2473;
This may have been secondary to autonomic dysfunction. It was an otherwise uneventful anesthetic and post-operative course and she was discharged on POD2.
- |||||||||| sevoflurane / Generic mfg.
Emergent Airway Management Through Self-inflicted Neck Wound (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2415;
A bougie was passed through the neck wound into the larynx and through the vocal cords followed by endotracheal intubation. Surgery completed with tracheostomy.
- |||||||||| sevoflurane / Generic mfg.
Anesthetic Management Of Non-cardiac Surgery In A Patient With Fontan Physiology (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2337;
Operative management began with mask induction with sevoflurane, oxygen, and room air to maintain oxygen saturations in the high 80's...The omentum was cauterized and chest tube site was sutured closed. This case will discuss management of anesthesia for noncardiac surgery in patients with congenital heart disease.
- |||||||||| fentanyl citrate / Generic mfg., sevoflurane / Generic mfg., midazolam hydrochloride / Generic mfg.
Anesthetic Management Of A Patient With Acute Porphyria And A Propofol Allergy: A Case Report. (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_1920;
The anesthetic plan included carefully verifying drugs using a Drug Database and general anesthesia induction with midazolam, fentanyl, and sevoflurane. Adequate management of patients with porphyria depends on awareness of the diagnosis and knowledge of triggering factors.
- |||||||||| sevoflurane / Generic mfg., dantrolene / Generic mfg.
Freaky Friday: A Case Of Self Resolving Malignant Hyperthermia (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_1843;
After extubation, the patient developed tachycardia, fever, profound increase in total creatine phosphokinase, and dark brown urine. The patient was admitted for close monitoring.
- |||||||||| fentanyl citrate / Generic mfg., sevoflurane / Generic mfg.
Challenging Airway: A Case Of Severe Keloids (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_1818;
An inhalation induction was done with sevoflurane combined with 20mg of propofol and 25mcg of fentanyl. Awake flexible fiberoptic intubation was successfully performed with a 7.5mm endotracheal nasal RAE tube to the right naris.
- |||||||||| sevoflurane / Generic mfg.
Robotic Hysterectomy In A Patient Who Had Prior Pneumectomy! (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_1815;
Fluid was limited to one liter and the patient was ventilated with 0.5 FiO2 as a measure of lung-protective strategy. Anesthesia was maintained with sevoflurane and the perioperative course was uneventful.
- |||||||||| fentanyl citrate / Generic mfg., sevoflurane / Generic mfg., epinephrine / Generic mfg.
Life-threatening Anaphylaxis In The NORA Setting (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_970;
General anesthesia was induced with fentanyl, propofol, followed by maintenance with sevoflurane with LMA...Patient was intubated, and anaphylaxis treatment was initiated with epinephrine boluses, steroids, antihistamines, IV fluids, and epinephrine infusion...Anaphylaxis is a known complication of echinococcal cysts. Discussion will focus on recognition and management of anaphylaxis per the Stanford Emergency Manual.
- |||||||||| Diabetes Insipidus Related To Sedation In The Intensive Care Unit: A Review Of The Literature (Virtual - Mobile App) - Aug 15, 2022 - Abstract #ASA2022ASA_212;
In particular, sevoflurane and dexmedetomidine appear to be implicated more frequently. While our study implicated sevoflurane as the causative agent in the highest percentage of ICU cases, a recent study of DI cases from anesthetics used intraoperatively found sevoflurane was responsible for the second highest percentage of cases after dexmedetomidine, despite the ubiquitous use of sevoflurane in anesthesia.
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