- |||||||||| levodropropizine / Generic mfg.
Journal: PREVALENCE AND ASSOCIATED RISK FACTORS OF HEPATITIS B VIRUS INFECTION IN LAFIA METROPOLIS, NASARAWA STATE, NIGERIA. (Pubmed Central) - Dec 2, 2024 A cross-sectional study was conducted from September to November 2023, utilizing a validated questionnaire to assess 461 randomly selected participants from four communities (Azuba, Bukan Sidi, Danka Sarki, and Doka), representing diverse sociodemographic profiles and varying degrees of exposure to risk factors associated with HBV infection...These findings highlight the need for targeted public health interventions and policies aimed at reducing HBV transmission among high-risk sociodemographic groups in Lafia Metropolis. This approach could potentially reduce the burden of HBV and improve health outcomes in affected communities.
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Journal: Levodropropizine for children and adolescents with acute post-viral cough: an evidence-based choice. (Pubmed Central) - Jul 30, 2024 Non-pharmacological remedies tend to be safe, but few substances have a documented degree of efficacy. Therefore, when managing children and adolescents with a post-viral cough, the practical approach may be based on levodropropizine use, which is preferable when the cough is particularly persistent and disturbs sleep.
- |||||||||| levodropropizine / Generic mfg., furosemide / Generic mfg.
Enrollment open, Trial completion date, Trial primary completion date: INFURO: The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases (clinicaltrials.gov) - Apr 16, 2024 P2/3, N=102, Recruiting, Therefore, when managing children and adolescents with a post-viral cough, the practical approach may be based on levodropropizine use, which is preferable when the cough is particularly persistent and disturbs sleep. Not yet recruiting --> Recruiting | Trial completion date: Dec 2024 --> Dec 2025 | Trial primary completion date: Jun 2024 --> Dec 2024
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PK/PD data, Journal: Pharmacokinetic Analysis of Levodropropizine and Its Potential Therapeutic Advantages Considering Eosinophil Levels and Clinical Indications. (Pubmed Central) - Feb 24, 2024 Interestingly, changes in an individual's plasma exposure to levodropropizine depending on eosinophil levels could be interpreted as a therapeutic advantage based on pharmacokinetic benefits linked to the clinical indications for levodropropizine. This study presents effective candidate covariates that can explain the inter-individual pharmacokinetic variability of levodropropizine and provides a useful perspective on the first-line choice of levodropropizine in the treatment of inflammatory respiratory diseases.
- |||||||||| levodropropizine / Generic mfg.
Clinical, Review, Journal: Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. (Pubmed Central) - Oct 22, 2021 An acute cough may significantly affect the quality of life of patients and their family.Several algorithms for the management of acute cough have been adopted and validated in clinical practice; however, unlike the latter, we developed an algorithm focused on pediatric age, and, also, in accordance to the Italian National Health System, which regularly follows the child from birth to all lifelong. Based on our findings, infants from 6 months, children, and adolescents with acute cough without cough pointers can be safely managed using well-known medications, preferably non-sedative agents, such as levodropropizine and/or natural compounds, including honey, glycerol, and herb-derived components.
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Clinical, Journal: Levodropropizine in children: over thirty years of clinical experience. (Pubmed Central) - Sep 26, 2021 Based on our findings, infants from 6 months, children, and adolescents with acute cough without cough pointers can be safely managed using well-known medications, preferably non-sedative agents, such as levodropropizine and/or natural compounds, including honey, glycerol, and herb-derived components. No abstract available
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Review, Journal: Characteristics, Properties and Analytical Methods for Determination of Dropropizine and Levodropropizine: A Review. (Pubmed Central) - Jul 9, 2021 In addition, the methodologies addressed the determination of dropropizine or levodropropizine in different types of matrices such as raw material, pharmaceutical formulations, plasma and urine. Despite the extensive clinical use of dropropizine, data from this review evidenced a still limited number of studies dealing with analytical methods for its determination in different matrices, which may be of concern since the applicability of these methods is important for quality assurance, efficacy and safety of the medicine.
- |||||||||| Baize’an (tislelizumab) / BeiGene
Review, Journal: Tislelizumab: First Approval. (Pubmed Central) - Jan 1, 2021 Tislelizumab has been investigated in haematological cancers and advanced solid tumours, leading to its approval in December 2019 in China for patients with relapsed or refractory classical Hodgkin's lymphoma after at least second-line chemotherapy. This article summarises the major milestones in the development of tislelizumab for this first approval for classical Hodgkin's lymphoma, and its potential upcoming approvals in other indications.
- |||||||||| levodropropizine / Generic mfg.
Review, Journal: Antitussive therapy: A role for levodropropizine. (Pubmed Central) - Mar 2, 2020 An international group of experts specialized in cough met to discuss the need to identify an effective antitussive treatment with a good tolerability profile. The aim of this expert review is to increase the knowledge about the cough mechanism and the activity of levodropropizine, a peripherally acting antitussive drug.
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