Ongoing

4

16

Europe

chloroquine, proguanil, ciprofloxacin, not applicable, Avloclor tablet 250mg, Paludrine tablet 100 mg, Ciproxin tablets 250 mg, Avloclor tablet 250mg, Paludrine tablet 100 mg, Ciproxin tablets 250 mg

Dstl

Chloroquine/proguanil is used for malaria chemoprophylaxis in areas where chloroquine-resistant Plasmodium falciparum malaria is prevalent, except in regions of Africa where chloroquine/proguanil is no longer effective. Ciprofloxacin is a fluoroquinolone antibiotic used to treat a wide variety of infections, such as traveller, s diarrhoea. Only healthy subjects will be treated in this study.