nitrofurantoin / Generic mfg. 
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  • ||||||||||  Journal:  The Behavior of Some Bacterial Strains Isolated from Fallow Deer Compared to Antimicrobial Substances in Western Romania. (Pubmed Central) -  Apr 28, 2023   
    The most efficient structures were beta-lactams, amikacin, and imipenem, to which all 47 strains studied (100%) were sensitive, followed by nitrofurantoin, to which 45 strains (95.7%) were sensitive, neomycin, to which 44 strains (93.6%) were sensitive, ceftiofur, to which 43 strains (91.5%) were sensitive, and trimethoprim/sulfamethoxazole and marbofloxacin, to which 42 strains (89.4%) were sensitive. (4) In wild animal populations, where a human presence is frequently reported, including a constant presence of domestic animals, despite the perceived low risk of emerging resistance to antimicrobials, resistance is likely to develop frequently.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Multi-faceted analysis of bacterial transformation of nitrofurantoin. (Pubmed Central) -  Mar 29, 2023   
    They showed increased cytotoxicity toward bacteria as determined by spectroscopy and flow cytometry. Results of this study suggest that nitrofurantoin biodegradation leads to formation of stable transformation products that significantly affect the physiology and structure of bacterial cells.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli. (Pubmed Central) -  Mar 28, 2023   
    Here, we determine the role of interspecies interactions on the dynamics of nitrofurantoin (NIT) resistance selection among Escherichia coli...Our results not only demonstrate the impact of interspecies interactions on the evolution of microbial traits but also show the importance of using synthetic microbial systems in unravelling relevant interactions and mechanisms affecting the evolution of antibiotic resistance. This finding implies that interspecies interactions should be considered to better understand and predict resistance evolution in the clinic as well as in nature.
  • ||||||||||  bleomycin / Generic mfg., amiodarone / Generic mfg., nitrofurantoin / Generic mfg.
    Reporting of Exposures by Patients With Interstitial Lung Disease During an Unstructured Clinician Interview or on a Questionnaire (Walter E. Washington Convention Center, Area E, Hall C (Lower Level)) -  Mar 25, 2023 - Abstract #ATS2023ATS_7682;    
    We found poor agreement on exposure status between clinician interview and a structured questionnaire for most ILD-associated exposures evaluated, with more exposures identified by the questionnaire compared to clinician interview. However, similarly frequent omission of mold or bird exposures highlights potential subjectivity in interpreting the relevance of an exposure by patients and clinicians.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome With Shock in the Setting of Nitrofurantoin (Walter E. Washington Convention Center, Area G, Hall C (Lower Level)) -  Mar 25, 2023 - Abstract #ATS2023ATS_6103;    
    She was started with intravenous corticosteroids and transitioned to oral prednisone once norepinephrine was weaned off...Cyclosporin is an alternative if resistance to corticosteroids or contraindication to corticosteroids is present...Clinicians should be aware of this condition for early diagnosis to prevent a fatal outcome. Also, DRESS survivors should be educated about strict avoidance of offending drugs.
  • ||||||||||  tetracycline / Generic mfg., nitrofurantoin / Generic mfg.
    Biomarker, Journal:  Ratiometric luminescent sensing of a biomarker for sugar consumption in an aqueous medium using a Cu(II) coordination polymer. (Pubmed Central) -  Mar 24, 2023   
    Intriguingly, KA@CP-S3 exhibits outstanding selective quenching of about 90.7% and 90.5% for the 125 mg dl and 150 mg dl strengths of sucrose, respectively, in aqueous solution along with other ranges in between. The photocatalytic degradation efficiency of KA@CP-S3 for the potentially harmful organic dye Bromophenol Blue displays 95.4%, which is the highest among the 13 dyes that were evaluated.
  • ||||||||||  nitrofurantoin / Generic mfg.
    ANTIBIOTIC USE AS A RISK FACTOR FOR INFLAMMATORY BOWEL DISEASE ACROSS THE AGES: A POPULATION-BASED COHORT STUDY (South Hall A, Poster Hall - McCormick Place) -  Mar 23, 2023 - Abstract #DDW2023DDW_896;    
    This risk was highest in the years immediately following antibiotic use, persisted across antibiotic classes impacting the gastrointestinal microbiome, and was associated with the development of both UC and CD. Thus, antibiotic stewardship may be important not only to limit the development of multidrug resistant organisms, but also to reduce the risk of IBD, particularly among older adults.
  • ||||||||||  nalidixic acid / Generic mfg., rifampicin / Generic mfg., nitrofurantoin / Generic mfg.
    Journal:  The post-transcriptional regulator CsrA affects multidrug resistance and biocontrol activity in Lysobacter enzymogenes. (Pubmed Central) -  Mar 16, 2023   
    Relative to common oral comparators, these data demonstrate excellent tebipenem in vitro activity against Enterobacterales isolated from patients receiving care in outpatient settings, including urology clinics and nursing homes. These results suggest that CsrA in LeC3 not only conferred its intrinsic MDR, but also contributed to its biocontrol activity.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Potential negative effect of long-term exposure to nitrofurans on bacteria isolated from wastewater. (Pubmed Central) -  Mar 16, 2023   
    This study reports the long-term impact of two nitrofuran representatives, nitrofurantoin (NFT) and furaltadone (FTD) on the bacterial strains Sphingobacterium siyangense FTD2, Achromobacter pulmonis NFZ2, and Stenotrophomonas maltophilia FZD2, isolated from a full-scale wastewater treatment plant...NFT and FTD elicited similar but not identical responses in all analyzed strains. The results obtained in this study provide new insights into the potential risks of the prolonged presence of antimicrobial compounds in the environment and contribute to a better understanding of the possible impacts of nitrofuran antibiotics on the bacterial cells.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Label free detection of multiple trace antibiotics with SERS substrates and independent components analysis. (Pubmed Central) -  Mar 14, 2023   
    In this work, we reported a combination between SERS and independent component analysis (ICA) to detect several trace antibiotics which are commonly used in aquacultures, including malachite green, furazolidone, furaltadone hydrochloride, nitrofurantoin, and nitrofurazone...With SERS substrates, the optimized ICA can identify trace molecules in a mixture at a concentration of 10 M achieving the correlation values to the reference molecular spectra of 71-98%. Furthermore, measurement results obtained from a real-world sample demonstration could also be recognized as an important basis to suggest this method is promising for monitoring antibiotics in a real aquatic environment.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  A Zn(II) coordination polymer as a dual sensor for ppb level detection of antibiotics and organo-toxins in a green solvent. (Pubmed Central) -  Mar 11, 2023   
    For patient characteristics, older age was associated with appropriate prescribing and Hispanic/Latino race was associated with inappropriate. The framework (CP-1) detected antibiotics (NFT (nitrofurantoin) and NZF (nitrofurazone)) and organo-toxin trinitrophenol in aqueous dispersed medium...The Stern-Volmer quenching constant values of CP-1 for the targeted analytes are admirable and the low detection limit (LOD) values for NFT, NZF and TNP are found to be 34.54, 67.79 and 43.93
  • ||||||||||  Journal:  Use of a product based on wood vinegar of Eucalyptus clone I144 used in the control of bovine mastitis. (Pubmed Central) -  Mar 7, 2023   
    The bacteria of the genus Staphylococcus and Corynebacterium were resistant to penicillin (PEN), rifampicin (RIF), nitrofurantoin (NIT), erythromycin (ERI), and ciprofloxacin (CIP). The extract was used in vivo in the post-dipping of dairy cows, which reduced the microbiological load present in the mammary glands from 4.74 to 2.54 CFU, indicating its future use as an antiseptic.
  • ||||||||||  Journal:  Prescribing patterns for treating common complications of spinal cord injury. (Pubmed Central) -  Mar 6, 2023   
    Thirty five percent of the total sample received a combination of two or more analgesics including fourth-line agents in the opiate class (hydromorphone, hydrocodone and morphine)...Medication management in SCI is complex. Tools are required that enable prescribers to choose evidence-based medical regimens and deprescribe potentially inappropriate medications for their patients with SCI.
  • ||||||||||  tetracycline / Generic mfg., nitrofurantoin / Generic mfg., fosfomycin tromethamine / Generic mfg.
    Clinical, Review, Journal:  Urinary ph and antibiotics, choose carefully. a systematic review. (Pubmed Central) -  Feb 8, 2023   
    We suggest performing urine cultures with antibiogram tests, in both acidic and alkaline media, to define the bacterial susceptibility profile. There is insufficient in vivo evidence to support whether choosing an antibiotic based on a patient's urinary pH or adding urinary pH modifiers will lead to a higher cure rate.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Empiric versus culture-based antibiotic therapy for UTIs in menopausal women. (Pubmed Central) -  Feb 7, 2023   
    There is insufficient in vivo evidence to support whether choosing an antibiotic based on a patient's urinary pH or adding urinary pH modifiers will lead to a higher cure rate. Outcomes for the empiric treatment of uncomplicated UTI with NF at both 7 and 14 days are not significantly different than outcomes with culture-based treatment.
  • ||||||||||  colistin sulphate / Generic mfg., nitrofurantoin / Generic mfg.
    Journal:  Identification of key amino acid residues in OqxB mediated efflux of fluoroquinolones using site-directed mutagenesis. (Pubmed Central) -  Feb 5, 2023   
    Based on our in silico modelling studies, both, hydrophobic residues (F180, L280, L621, F626) and polar residues (R48, E50, E184, R157, R774) were found to be located at this site. The present work reports the importance of these key amino acid residues and the crucial ion-pair interactions at the substrate-binding pocket, thereby establishing their role in OqxB mediated efflux and the resultant resistance development against fluoroquinolones.