furosemide / Generic mfg. 
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  • ||||||||||  Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
    [VIRTUAL] Glomerular Tip Lesion FSGS: A Rare Case of Nephrotic Syndrome in African Americans (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_2128;    
    He trialed hydrochlorothiazide and furosemide without success...Outpatient workup was unrevealing, and was managed with enalapril and torsemide...Cyclosporine caused gastrointestinal upset, and so patient switched to tacrolimus...Resistance to one immunosuppressive treatment is not always associated with resistance to other treatment modalities. PLEX and rituximab should be considered in glomerular tip lesion in African Americans
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] A Delayed Diagnosis of Gordon Syndrome: Better Late Than Never! (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_2025;    
    Upon presentation, he had been on furosemide 40mg and sodium polystyrene sulfonate (SPS) 30mg daily for the last 6 years for K+ values as high as 7 mEq/L with normal renal function...Thiazides are the treatment of choice. When suspected, genetic testing confirms diagnosis, prompting disease-guided therapy and preventing life-threatening consequences.
  • ||||||||||  [VIRTUAL] Hyponatremia: It’s in the Eye of the Beholder (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1919;    
    Hypertension was treated with labetalol, amlodipine, and pain with opioids...She was treated with free water restriction, 3% saline, salt tablets, and furosemide...Discussion Acyclovir was started and corticosteroids stopped...Desalination needs to be considered in the correction of hyponatremia in SIADH, hyponatremia correction in HZO takes an average of 7 days although up to 4 months has been reported in 1 case series1. HZO should be considered in the differential diagnosis of SIADH.
  • ||||||||||  Bystolic (nebivolol) / Menarini, AbbVie
    [VIRTUAL] A Case of Disappearing Hypertension: Difficulties of Managing Hypertension in a Breast Cancer Survivor (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1554;    
    Blood pressure continued to be high at clinic and home, nebivolol was changed to amlodipine 5mg daily...Furosemide 20 mg PO daily was added which resolved the edema but headache persisted...Discussion Often patient after mastectomy with SNB or ALND avoids taking blood pressure on affected limb regardless of lymphedema in order to prevent lymphedema. Despite this, the evidence for this is sparse with most recent studies reporteding blood pressure measurement in ipsilateral affected arm as not being risk factor for lymphedema.
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] Rhabdomyolysis and High Catabolic State in Patients with COVID-19 Who Develop Dialysis-Requiring AKI (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1490;    
    Intravenous furosemide was attempted with poor responses...However the excessive immune response and cytokine storms which often seen in COVID-19 can promote to high catabolic state and rhabdomyolysis and therefore it will contribute to rapid worsening on renal function. Early detection and promptly supportive treatment with RRT may help to improve the vital prognosis of COVID-19.
  • ||||||||||  [VIRTUAL] Renal Artery Thrombosis with Infarction in a Patient with Mild COVID-19 (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1488;    
    Her medications included aspirin, clopidogrel, furosemide, and insulin...On interdisciplinary discussion, the patient was managed conservatively with anticoagulation without acute intervention and was discharged home on apixaban...Although it requires a high index of suspicion, renal infarction should be considered part of the differential when evaluating a patient with COVID-19 infection presenting with abdominal pain or acute kidney injury. Initiation of anticoagulation should be considered with consideration of risks involved.
  • ||||||||||  hydralazine hydrochloride / Generic mfg.
    [VIRTUAL] Diuretic Resistance: When to Consider Hydralazine? (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_842;    
    This is not likely due to better renal diuretic delivery since the patient received constant IV infusions of two diuretics at doses well above their ceiling. Further clinical trials and mechanistic studies of hydralazine-diuretic interaction are warranted.
  • ||||||||||  Eraxis (anidulafungin) / RaQualia
    [VIRTUAL] AKI After Procedures of Orthotopic Liver Transplant: Risk Factors, Renal Outcomes and Survival (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_710;    
    The development of AKI seems to be multifactorial influencing baseline characteristics of patients before transplantation and renal insults during surgery and intensive care stay. AKI was associated with higher mortality at 7 and 30 days, in addition to lower GFR at patient discharge and higher risk of CKD.
  • ||||||||||  furosemide / Generic mfg., spironolactone / Generic mfg.
    [VIRTUAL] The Effect in Renal Function and Vascular Decongestion in Type 1 Cardiorenal Syndrome Treated with Two Strategies of Diuretics: A Randomized Clinical Trial (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_645;    
    The CD group consist in the combination of diuretics trying to block different tubular segments, including 4 consecutive days of oral chlortalidone 50mg, spironolactone 50mg and infusion of furosemide 100mg. In patients with SCR-1 and high risk of resistance to diuretics, the strategy of CD compared to SF, offers the same frequency of renal recovery, diuresis, vascular decongestion and adverse events, so it can be considered as an alternative, especially in cases where it is not considered advisable to increase furosemide.
  • ||||||||||  Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
    [VIRTUAL] DECOMPENSATED LIVER CIRRHOSIS FROM NON-HEMOCHROMATOSIS IRON OVERLOAD () -  Oct 11, 2020 - Abstract #AASLD2020AASLD_1439;    
    Clinicians must be aware of other conditions in addition to hemochromatosis that can lead to excess iron deposition in the liver. This excess can eventually lead to significant liver damage and extensive liver cirrhosis.
  • ||||||||||  Pradaxa (dabigatran etexilate) / Boehringer Ingelheim
    [VIRTUAL] Flecainide Induced Myalgias. A Rare but Important Adverse Reaction (OnDemand) -  Oct 10, 2020 - Abstract #AHA2020AHA_4754;    
    In the appropriate clinical context, healthcare providers should be aware of this rare, reversible adverse effect, to prevent extensive inflammatory or neuromuscular disease workup. As our case illustrates, early discontinuation of flecainide can resolve myalgias and prevent long-term sequelae.
  • ||||||||||  Alverix (amiloride hydrochloride) / Remedica
    Journal:  Effects of extreme potassium stress on blood pressure and renal tubular sodium transport. (Pubmed Central) -  Oct 9, 2020   
    This may be due to the extreme degree of potassium stress, the low Na:K ratio, the duration of treatment, and the development of other coinciding events, such as diabetes insipidus. These factors must be taken into consideration when studying the physiologic effects of dietary potassium loading and depletion.
  • ||||||||||  Triglide (fenofibrate) / Vectura, Shionogi, Frumeron (indapamide) / Remedica
    Clinical, Review, Journal:  Drug treatments in patients with cardiac diseases and epilepsy. (Pubmed Central) -  Oct 8, 2020   
    Intercalated cell number and function along with renal tubular flow are determinants of pyelonephritis risk. Available data show that the treatment of patients with epilepsy and vascular comorbidities is challenging and requires the appropriate knowledge of pharmacological properties of drugs and drug interactions.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Furosemide-Associated Drug Reaction With Eosinophilia and Systemic Symptoms. (Pubmed Central) -  Oct 8, 2020   
    Available data show that the treatment of patients with epilepsy and vascular comorbidities is challenging and requires the appropriate knowledge of pharmacological properties of drugs and drug interactions. No abstract available
  • ||||||||||  Doburan (dobutamine) / VHB Life Sciences, furosemide / Generic mfg.
    Clinical, Journal:  Postoperative pulmonary edema following vitrectomy in patients with ischemic heart disease and diastolic dysfunction in the post-anesthetic care unit: Two case reports. (Pubmed Central) -  Oct 2, 2020   
    Physicians should be alert to the potential development of PE as a postoperative complication in patients with left ventricular (LV) diastolic dysfunction and ischemic heart disease, even if the patient has undergone a procedure with mild hemodynamic change and minimal surgical stimulation such as vitrectomy. We propose that physicians treating elderly patients with LV diastolic dysfunction and ischemic heart disease undergoing vitrectomy should consider the use of intraoperative transthoracic echocardiogram or transesophageal echocardiogram with continuous monitoring of blood pressure, using devices such as arterial catheter devices.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Brain osmo-sodium sensitive channels and the onset of sodium appetite. (Pubmed Central) -  Sep 30, 2020   
    For this purpose, we used TRPV1-knockout mice to investigate sodium depletion-induced drinking at different times (2/24 h) after furosemide administration combined with a low sodium diet (FURO-LSD)...In addition, there was an increase in the OVLT-Na expression of SD-WT 24 h after FURO-LSD, suggesting the participation of OVLT-Na channels in the appearance of sodium appetite, possibly as an anticipatory response in order to limit sodium intake and to induce thirst. Our work demonstrates changes in the expression of different osmo‑sodium-sensitive channels at specific nuclei, related to the body sodium status in order to stimulate an adequate drinking.
  • ||||||||||  furosemide / Generic mfg.
    Preclinical, Journal:  Na-K-2Cl symporter contributes to γ-aminobutyric acid-evoked excitation in rat enteric neurons. (Pubmed Central) -  Sep 26, 2020   
    Blockade of NKCC by bumetanide (50 μmol/L) or furosemide (300 μmol/L) suppressed the depolarizing responses to GABA...The results suggest that ENS neurons continuously express NKCC2 since P1 and NKCC1 since P14, which contribute to the accumulation of Cl in ENS neurons and GABA-evoked depolarization in neonate and adult ENS neurons. These results provide the first direct evidence for the contribution of both NKCC2 and NKCC1 to the GABA-mediated depolarization.
  • ||||||||||  furosemide / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  Diuretic Vascular Filling in the Initial Management of Acute PE With Right Ventricular Dysfunction Normotensive (clinicaltrials.gov) -  Sep 25, 2020   
    P4,  N=60, Completed, 
    • The choice between single-bolus and split-bolus protocols depends on the context, but split-bolus protocols should be favoured whenever possible to decrease patient irradiation. Recruiting --> Completed | Trial completion date: Apr 2019 --> Apr 2020 | Trial primary completion date: Dec 2018 --> Apr 2020
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3. (Pubmed Central) -  Sep 24, 2020   
    Compounds 10 and 16 were inhibitors for OAT1, and compounds 1-3, 10, and 16 were inhibitors for OAT3 with IC values less than 5.0 μM. Dihydrophenanthrene 1 markedly altered the pharmacokinetic parameters of the diuretic drug furosemide, a known substrate of both OAT1 and OAT3, in vivo.
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] Nebulized Furosemide for Chronic Obstructive Pulmonary Disease (COPD) () -  Sep 23, 2020 - Abstract #ASHP2020ASHP_174;    
    Dihydrophenanthrene 1 markedly altered the pharmacokinetic parameters of the diuretic drug furosemide, a known substrate of both OAT1 and OAT3, in vivo. Learning Objectives: Describe the efficacy and safety of nebulized furosemide for the treatment of COPD.
  • ||||||||||  Doburan (dobutamine) / VHB Life Sciences, furosemide / Generic mfg.
    Clinical, Review, Journal:  The Role of Pharmacists in Home Medical Care of Patients with Heart Failure (Pubmed Central) -  Sep 23, 2020   
    Furthermore, dobutamine and furosemide injections are not dispensed extramurally, and therefore might become an impediment to the cooperation of the team. In this symposium, I consider and discuss the role of pharmacists in a home medical care team for patients with terminal CHF.