furosemide / Generic mfg. 
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  • ||||||||||  furosemide / Generic mfg.
    Journal:  Nocturia: A Marker of Furosemide Treatment Response? An exploratory study. (Pubmed Central) -  Oct 30, 2020   
    Although epidemiological studies have found nocturia to be associated with diuretic use [1], randomized trials have shown that well-timed diuretics improve nocturia severity [2,3], suggesting that the well-described link between nocturia and mortality may be mediated by its status as a marker of volume overload states [4]. Despite their inclusion in current nocturia guidelines [5], diuretics remain underutilized in the treatment of nocturia [6], and their effect on nocturia in patients with volume overload has not been well studied.
  • ||||||||||  Jardiance (empagliflozin) / Eli Lilly, Boehringer Ingelheim
    Journal:  Empagliflozin prevents doxorubicin-induced myocardial dysfunction. (Pubmed Central) -  Oct 28, 2020   
    Empagliflozin attenuates the cardiotoxic effects exerted by doxorubicin on LV function and remodelling in nondiabetic mice, independently of glycaemic control. These findings support the design of clinical studies to assess their relevance in a clinical setting.
  • ||||||||||  [VIRTUAL] Taking the Next Step in the Management of ADPKD: Insights from a Multidisciplinary Panel () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_4050;    
    Inhibitors of CYP3A: Concomitant use of JYNARQUE with drugs that are moderate or strong CYP3A inhibitors (e. g. , ketoconazole, itraconazole, lopinavir/ritonavir, indinavir/ritonavir, ritonavir, and conivaptan) increases tolvaptan exposure...Avoid concomitant use of JYNARQUE with strong CYP3A inducers• OATP1B1/3 and OAT3 Transporter Substrates: Patients who take JYNARQUE should avoid concomitant use with OATP1B1/B3 and OAT3 substrates (e. g. , statins, bosentan, glyburide, nateglinide, repaglinide, methotrexate, furosemide), as the plasma concentrations of these substrates may be increased...Patients who take JYNARQUE, should avoid concomitant use with BCRP substrates (e. g. , rosuvastatin)• V2-Receptor Agonist: Tolvaptan interferes with the V2-agonist activity of desmopressin (dDAVP)...In general, JYNARQUE should be discontinued during pregnancy. Advise women not to breastfeed during treatment with JYNARQU
  • ||||||||||  risperidone / Generic mfg., Egis, thyroxine / Generic mfg., lithium / Generic mfg.
    [VIRTUAL] An A-Tip-ical Side Effect of Lithium () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3937;    
    Medications included levothyroxine, Risperdal, and lithium...Lithium was discontinued, and the patient underwent diuresis with Lasix/albumin infusions...Variable visceral cell hyperplasia. (Hematoxylin and eosin, 400X)
  • ||||||||||  CoAprovel (irbesartan hydrochlorothiazide) / Sanofi
    [VIRTUAL] IgA Nephropathy in a Patient with Beta-Thalassemia Minor: A Case Report () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3933;    
    He was treated initially, by another provider, with hydrochlorothiazide/irbesartan and carvedilol for hypertensive nephropathy...We managed successfully with irbesartan, amlodipine, NaHCO3 then furosemide...Significantly, at the time of biopsy, all cases had fibrosis in various degrees ranging from partial to global sclerosis with fibrous crescents. Notably, prior cases occurred in Asian ethnicities, were IgAN is prevalent; our case is the first Hispanic affected patient.
  • ||||||||||  Veltassa (patiromer) / Vifor
    [VIRTUAL] Laxative Use in Acute Hyperkalemia () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3884;    
    In this case lactulose was successfully implemented in treating severe hyperkalemia when all other measures failed. Controlled use of laxatives can be considered as a means to control hyperkalemia in patients who are not candidates for renal replacement therapy.
  • ||||||||||  Actemra IV (tocilizumab) / Roche, JW Pharma
    [VIRTUAL] A Case of Masked AKI () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3777;    
    Her management included tocilizumab, mechanical ventilation, vasopressors, ECMO, and antibiotics...Also, periodic furosemide was given to mitigate her positive fluid balance...In his case, we believe a baseline small muscle mass, critical illness sarcopenia, and marked volume expansion conspired to mask significant AKI in our patient. Documentation of AKI by measuring CysC led to adjustments in drug dosing.
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] Transient Anuric AKI Secondary to Parkinson Disease () -  Oct 27, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3763;    
    Renal Scintigraphy using MAG3 technique along with furosemide was performed twice, seven days apart, the first away from an anuric episode and the second during...The patient had her Parkinson's treatment optimized and the frequency and severity of the episodes decreased. Discussion Our findings allow us to speculate that Parkinson's disease could cause neurogenic dysfunction of the upper collecting system that manifests by episodes of intermittent anuria leading to acute kidney injury.
  • ||||||||||  furosemide / Generic mfg.
    Clinical, Journal:  Case report: severe myoclonus associated with oral midodrine treatment for hypotension. (Pubmed Central) -  Oct 23, 2020   
    Oral midodrine is widely used in the treatment of orthostatic hypotension, recurrent reflex syncope and dialysis-associated hypotension and the adverse effects are mostly mild. However, clinicians should be alert for midodrine-induced myoclonus, especially in patients with CKD.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Adherence to heart failure management medications following cardiac resynchronization therapy. (Pubmed Central) -  Oct 22, 2020   
    Adherence to HF medications significantly improved among HF patients post-CRT implantation. Further research is needed to better understand the underlying determinants of this effect, including whether the effect is attributable to factors such as enhanced patient monitoring and improved access to high-quality specialized HF care among patients receiving CRT.
  • ||||||||||  Actemra IV (tocilizumab) / Roche, JW Pharma, Valcyte (valganciclovir) / Roche, Mitsubishi Tanabe, Kineret (anakinra) / SOBI
    Enrollment change, Trial completion date, Trial primary completion date:  Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants (clinicaltrials.gov) -  Oct 19, 2020   
    P=N/A,  N=1600, Recruiting, 
    Diuretic dose and NYHA functional class are independent predictors of mortality in ATTR-CM patients and provide incremental value to existing ATTR-CM risk scores. N=500 --> 1600 | Trial completion date: Sep 2020 --> Sep 2021 | Trial primary completion date: Sep 2020 --> Sep 2021
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] Hypermagnesemia Causing Respiratory Airway Compromise In Fetus Of Eclamptic Patient () -  Oct 17, 2020 - Abstract #ASA2020ASA_1372;    
    Newborn was managed with intravenous calcium, volume expansion and furosemide while preparing for exchange blood transfusion with resolution of hypermagnesemia and extubation in 24 hours. Fetal neuromuscular recovery could occur if action of magnesium is quickly blocked in neonate with good renal function.
  • ||||||||||  furosemide / Generic mfg.
    [VIRTUAL] Pulmonary Edema During Cesarean Hysterectomy () -  Oct 17, 2020 - Abstract #ASA2020ASA_1277;    
    Ventilation difficulty resolved after furosemide administration with robust urine output. The patient was transferred to the ICU still intubated in stable condition for post-operative monitoring and was extubated later that evening.
  • ||||||||||  Remodulin (treprostinil diethanolamine oral) / United Therapeutics, Tyvaso (treprostinil) / United Therapeutics
    [VIRTUAL] Regional Anesthesia For C-section In Woman With Eisenmenger's Syndrome () -  Oct 17, 2020 - Abstract #ASA2020ASA_1127;    
    Viable preterm female neonate with APGARS 9/9 was delivered uneventfully. Received oxytocin for hemostasis, Morphine via epidural post-op pain control.