furosemide / Generic mfg. 
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  • ||||||||||  Henletor (torsemide) / Orchid
    Journal:  Renin-Angiotensin-Aldosterone System Activation and Diuretic Response in Ambulatory Patients With Heart Failure. (Pubmed Central) -  May 29, 2022   
    Euvolemic ambulatory adults with chronic heart failure were administered torsemide in a monitored environment...The median home diuretic dose was 80-mg furosemide equivalents...Among multiple measures of RAAS activation, higher plasma total and active renin levels were consistently associated with lower diuretic response. These findings highlight the potential drivers of diuretic resistance and underscore the need for high-quality trials of decongestive therapy enhanced by RAAS blockade.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Diuretic Renal Scintigraphy Protocol Considerations. (Pubmed Central) -  May 26, 2022   
    The exam accuracy is highly dependent upon and benefits from close attention to the protocol. This article reviews kidney anatomy and physiology, patient preparation, available radiopharmaceuticals, diuretic administration, acquisition, processing, quantification, and interpretation criteria.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Neonatal acute kidney injury risk stratification score: STARZ study. (Pubmed Central) -  May 26, 2022   
    These neonates with a higher risk stratification score need intense monitoring and daily kidney function assessment. With this intensification of research in the field of AKI risk stratification prediction, there is hope that we will be able to decrease morbidity and mortality associated with AKI in this population.
  • ||||||||||  furosemide / Generic mfg.
    Retrospective data, Journal:  Long-Term Outcomes and Risk Stratification of Patients With Heart Failure With Recovered Ejection Fraction. (Pubmed Central) -  May 26, 2022   
    An all-cause mortality Cox proportional hazard risk model incorporating New York Heart Association functional class, BNP and diuretic dose at the time of recovery showed excellent risk discrimination (c-statistic 0.79) and calibration. In conclusion, patients with heart failure with recovered ejection fraction have heterogenous clinical outcomes and are not "cured." A risk model using New York Heart Association functional class, BNP, and diuretic dose can accurately stratify mortality risk.
  • ||||||||||  tolvaptan / Generic mfg.
    Retrospective data, Journal:  Cisterna chyli as an optimal marker of tolvaptan response in severe cirrhotic ascites. (Pubmed Central) -  May 26, 2022   
    Cumulative liver transplantation-free survival rates were significantly higher in patients with cisterna chyli dilatation than in those without (p = 0.028). Our findings suggest a strong association of cisterna chyli with tolvaptan treatment response in patients with cirrhosis and hepatic edema.
  • ||||||||||  Nuzyra (omadacycline) / Paratek
    Compatibility Of Omadacycline With Select Parenteral Products In Simulated Y-site Administration (Exhibit and Poster Hall) -  May 21, 2022 - Abstract #ASMMicrobe2022ASM_Microbe_1572;    
    However, the combination of furosemide and omadacycline was incompatible at standardized concentrations and should not be infused together via Y-site. Overall, the administration of both omadacycline and common inpatient medications are suggested to be safe, but furosemide may require a separate IV line or other appropriate measures to avoid patient harm.
  • ||||||||||  furosemide / Generic mfg., ibuprofen / Generic mfg.
    Journal:  Determining risk factors for triple whammy acute kidney injury. (Pubmed Central) -  May 20, 2022   
    Triple treatment involving an ACE inhibitor, furosemide, and NSAID results in blood pressure levels similar to double treatment with ACEI and furosemide. Additionally, the male and female hypertensive models act similarly in most situations, except for the ACE inhibitor and NSAID double treatment.
  • ||||||||||  prednisone / Generic mfg., heparin sodium injection / Generic mfg., furosemide / Generic mfg.
    A CHILD WITH NEW ONSET NEPHROTIC SYNDROME AS THE MAIN MANIFESTATION OF SARS-COV-2 INFECTION () -  May 19, 2022 - Abstract #ESPID2022ESPID_1238;    
    Due to the risk of thromboembolic events, she received, prophylactic, low dose heparin SC for 12 days...Learning Points/ This is the first paediatric case with new onset nephrotic syndrome as the main manifestation of COVID-19 infection in a febrile child with no respiratory or gastrointestinal symptoms. Although references are rare so far, paediatricians should be aware of SARS-CoV-2 as a cause of nephrotic syndrome either new-onset or relapse
  • ||||||||||  NEONATAL RSV POSTIVE BRONCHIOLITIS WITH FULMINANT VIRAL SEPTIC SHOCK ASYSTOLE DISSEMINATED INTRAVASCULAR COAGULATION AND PULMONARY HAEMORRHAGE () -  May 19, 2022 - Abstract #ESPID2022ESPID_970;    
    CPR started, baby intubated, cannulas inserted, 2 doses of adrenaline and 30ml/kg of NS bolus given, partial septic screening done, started on triple antibiotics amoxicillin, cefotaxime, gentamicin...Started on morphine infusion, IV fluids, Lasix...Acyclovir, vitamin K for 9, 6 days respectively...Case Presentation Summary: Main purpose of presenting this clinical case is that RSV postive bronchiolitis can present with asystole, septic shock, pulmonary haemorrhage, DIC, and lobar pneumonia. Learning Points/ RSV postive bronchiolitis with all complications can mimic bacterial sepsis
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Design and Evaluation of Floating Micro-Carriers for Effective Delivery of a Hydrophobic Drug. (Pubmed Central) -  May 18, 2022   
    More importantly, due to the transferability of deep learning, the smartphone-based MIP-ECL systems can facilitate the real-time monitoring of biochemical analytes in multiple fields. In vivo study will be performed in future to accomplish better results regarding bioavailability of drug loaded microparticles.
  • ||||||||||  furosemide / Generic mfg.
    Retrospective data, Journal:  Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections. (Pubmed Central) -  May 17, 2022   
    The higher risk factors of AKI include males [odds ratio (OR) = 3.237; 95% confidence interval (95%CI) = 1.426-7.350], digestive system diseases [OR = 2.481 (1.127-5.463)], using furosemide (>20 mg/day) [OR = 2.473 (1.102-5.551)], and baseline serum creatinine [OR = 0.994 (0.990-0.999)]...These risk factors should be taken into consideration when initiating PMB-based therapy. The serum creatinine value should be closely monitored when using PMB.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Inhibition of Na /H exchanger-3 (NHE3) results in hyperphosphatemia without major alterations in Ca homeostasis. (Pubmed Central) -  May 14, 2022   
    NHE3 mice were normocalcemic with normal urinary Ca excretion, but had greater furosemide-induced calciuresis, suggesting increased Na -K -Cl cotransporter (NKCC2) activity...Collectively, inhibition of NHE3 results in hyperphosphatemia without major alterations in Ca homeostasis. Data suggest that NHE3 inhibitors may constitute significant health risks due to alterations in renal function and Pi homeostasis.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Loop-Diuretics Increase Pendrin through alpha-ketoglutarate receptor, Oxgr1. (Pubmed Central) -  May 14, 2022   
    OXGR1 is required for post-translational upregulation of pendrin protein post diuretic challenge, consistent with activation of a aKG-OXGR1-pendrin signaling axis. Upregulation of NCC and residual pendrin activity may be sufficient to brake the loop-diuretic response.