furosemide / Generic mfg. 
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  • ||||||||||  furosemide / Generic mfg.
    Observational data, Journal:  Fluid restriction management in the treatment of COVID-19: a single-center observational study. (Pubmed Central) -  Oct 23, 2022   
    Fluid restriction management was performed using furosemide and continuous renal replacement therapy as needed unless hemodynamic instability or hyperlactatemia was present...The lengths of hospital stay were 5 (2-7), 9 (7-15), and 18 (12-26) days [P < 0.001, Jonckheere-Terpstra test]. In our fluid restriction management, patients with severe COVID-19 had significant longer hospital length of stay, weight loss, especially those who were transferred to the hospital.
  • ||||||||||  acetazolamide / Generic mfg., furosemide / Generic mfg.
    Review, Journal:  Changes in Proximal Tubular Reabsorption Modulate Microvascular Regulation via the TGF System. (Pubmed Central) -  Oct 22, 2022   
    Furthermore, combination use of SGLT2 inhibitors and angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs). in diabetes can decrease inflammatory pathways, improve renal oxygenation, and delay the progression of diabetic nephropathy.
  • ||||||||||  furosemide / Generic mfg.
    Journal, HEOR:  Impact of Outpatient Diuretic Infusion Therapy on Healthcare Cost and Readmissions. (Pubmed Central) -  Oct 21, 2022   
    Adult patients who were included in this study received a furosemide dose of 40 mg intravenously (infusion over 3 hours) at the clinic visit...This treatment strategy has no detrimental effects in addition to generating substantial financial savings. It appears to be a useful addition to the existing medical treatment regimens chronic HF patients.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Multisystem inflammatory syndrome-neonates (MIS-N) associated with acute kidney injury: A case report. (Pubmed Central) -  Oct 18, 2022   
    Initially, the baby was managed with mechanical ventilation, inotropic support, antibiotics, fluid restriction and furosemide infusion...On follow up, he was gaining weight satisfactorily, with no sequalae. Atypical presentation of multisystem involvement in the form of AKI should not be missed since it is treatable with definitive and supportive care and has a favorable outcome.
  • ||||||||||  dexamethasone / Generic mfg., furosemide / Generic mfg.
    Journal:  Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report. (Pubmed Central) -  Oct 18, 2022   
    Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.
  • ||||||||||  furosemide / Generic mfg., aminophylline / Generic mfg.
    Review, Journal:  The diuretic effect of adding aminophylline or theophylline to furosemide in pediatric populations: a systematic review. (Pubmed Central) -  Oct 18, 2022   
    Our systematic review demonstrated that the co-administration of furosemide and aminophylline/theophylline could potentially yield better diuretic effects of urine output and negative fluid balance than furosemide alone in pediatric patients with fluid overload. Given the substantial degree of heterogeneity and low level of evidence, future adequately powered trials are warranted to provide evidence regarding the combined use of aminophylline/theophylline and furosemide as diuretic in the pediatric population.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Suspected sequential left atrial ruptures in a dog with myxomatous mitral valve disease. (Pubmed Central) -  Oct 18, 2022   
    Rupture of the LA free wall secondary to MMVD was suspected, and medical therapy with furosemide and pimobendan was initiated...In light of the dog's history, the latter finding was suspected to be secondary to a further rupture of the LA wall due to MMVD, this time affecting the interatrial septum. The images described here allow us to suspect that sequential LA wall ruptures developed over time in the same subject affected by MMVD, a clinical presentation not previously described in veterinary medicine.
  • ||||||||||  Sarscov2 vaccine as a possible cause of herpes zoster reactivations () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_2757;    
    The annual incidence is four cases per 1,000 population, increasing in those over 60years of age and in females.Can SARS-CoV-2mRNA vaccine trigger reactivation of disseminated HZ?Patient 1 is a 95-year-old institutionalized woman with a history of allergy to non-steroidal anti-inflammatory drugs (NSAIDs), type 2 diabetes mellitus, renal failure and chronic respiratory failure, and hyperthyroidism on regular treatment with iron, folic acid, spironolactone, thiamazole, and furosemide...Patient 2 is a 91-year-old woman with a history of arterial hypertension, vascular ulcers in both lower extremities, cardiac arrhythmia due to atrial fibrillation and severe mitral and tricuspid regurgitation with severe pulmonary hypertension: ASA, digoxin, losartan, amlodipine, furosemide, fentanyl, and omeprazole, who attended the emergency department for pain in the left iliac fossa radiating to the back, after which he debuted with vesicular umbilicated lesions with a linear course in the left abdominal region and multiple lesions scattered over the trunk and extremities...Although active SARS-CoV-2 infection was ruled out in the cases presented,there are studies that link the appearance of herpes zoster as a marker of SARS-CoV-2 infection To our knowledge, these cases are the first described in the scientific literature in which the occurrence of disseminated HZ is temporally associated with SARS-CoV-2 vaccination as a possible adverse effect. Further studies are needed to confirm this association, which should be taken into account in elderly patients at risk of immunosuppression.Both patients signed informed consent, including consent for data sharing.
  • ||||||||||  Sarscov2 vaccine as a possible cause of herpes zoster reactivations () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_2756;    
    The annual incidence is four cases per 1,000 population, increasing in those over 60years of age and in females.Can SARS-CoV-2mRNA vaccine trigger reactivation of disseminated HZ?Patient 1 is a 95-year-old institutionalized woman with a history of allergy to non-steroidal anti-inflammatory drugs (NSAIDs), type 2 diabetes mellitus, renal failure and chronic respiratory failure, and hyperthyroidism on regular treatment with iron, folic acid, spironolactone, thiamazole, and furosemide...Patient 2 is a 91-year-old woman with a history of arterial hypertension, vascular ulcers in both lower extremities, cardiac arrhythmia due to atrial fibrillation and severe mitral and tricuspid regurgitation with severe pulmonary hypertension: ASA, digoxin, losartan, amlodipine, furosemide, fentanyl, and omeprazole, who attended the emergency department for pain in the left iliac fossa radiating to the back, after which he debuted with vesicular umbilicated lesions with a linear course in the left abdominal region and multiple lesions scattered over the trunk and extremities...Although active SARS-CoV-2 infection was ruled out in the cases presented,there are studies that link the appearance of herpes zoster as a marker of SARS-CoV-2 infection To our knowledge, these cases are the first described in the scientific literature in which the occurrence of disseminated HZ is temporally associated with SARS-CoV-2 vaccination as a possible adverse effect. Further studies are needed to confirm this association, which should be taken into account in elderly patients at risk of immunosuppression.Both patients signed informed consent, including consent for data sharing.
  • ||||||||||  Sarscov2 vaccine as a possible cause of herpes zoster reactivations () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_2755;    
    The annual incidence is four cases per 1,000 population, increasing in those over 60years of age and in females.Can SARS-CoV-2mRNA vaccine trigger reactivation of disseminated HZ?Patient 1 is a 95-year-old institutionalized woman with a history of allergy to non-steroidal anti-inflammatory drugs (NSAIDs), type 2 diabetes mellitus, renal failure and chronic respiratory failure, and hyperthyroidism on regular treatment with iron, folic acid, spironolactone, thiamazole, and furosemide...Patient 2 is a 91-year-old woman with a history of arterial hypertension, vascular ulcers in both lower extremities, cardiac arrhythmia due to atrial fibrillation and severe mitral and tricuspid regurgitation with severe pulmonary hypertension: ASA, digoxin, losartan, amlodipine, furosemide, fentanyl, and omeprazole, who attended the emergency department for pain in the left iliac fossa radiating to the back, after which he debuted with vesicular umbilicated lesions with a linear course in the left abdominal region and multiple lesions scattered over the trunk and extremities...Although active SARS-CoV-2 infection was ruled out in the cases presented,there are studies that link the appearance of herpes zoster as a marker of SARS-CoV-2 infection To our knowledge, these cases are the first described in the scientific literature in which the occurrence of disseminated HZ is temporally associated with SARS-CoV-2 vaccination as a possible adverse effect. Further studies are needed to confirm this association, which should be taken into account in elderly patients at risk of immunosuppression.Both patients signed informed consent, including consent for data sharing.
  • ||||||||||  Sarscov2 vaccine as a possible cause of herpes zoster reactivations () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_2754;    
    The annual incidence is four cases per 1,000 population, increasing in those over 60years of age and in females.Can SARS-CoV-2mRNA vaccine trigger reactivation of disseminated HZ?Patient 1 is a 95-year-old institutionalized woman with a history of allergy to non-steroidal anti-inflammatory drugs (NSAIDs), type 2 diabetes mellitus, renal failure and chronic respiratory failure, and hyperthyroidism on regular treatment with iron, folic acid, spironolactone, thiamazole, and furosemide...Patient 2 is a 91-year-old woman with a history of arterial hypertension, vascular ulcers in both lower extremities, cardiac arrhythmia due to atrial fibrillation and severe mitral and tricuspid regurgitation with severe pulmonary hypertension: ASA, digoxin, losartan, amlodipine, furosemide, fentanyl, and omeprazole, who attended the emergency department for pain in the left iliac fossa radiating to the back, after which he debuted with vesicular umbilicated lesions with a linear course in the left abdominal region and multiple lesions scattered over the trunk and extremities...Although active SARS-CoV-2 infection was ruled out in the cases presented,there are studies that link the appearance of herpes zoster as a marker of SARS-CoV-2 infection To our knowledge, these cases are the first described in the scientific literature in which the occurrence of disseminated HZ is temporally associated with SARS-CoV-2 vaccination as a possible adverse effect. Further studies are needed to confirm this association, which should be taken into account in elderly patients at risk of immunosuppression.Both patients signed informed consent, including consent for data sharing.
  • ||||||||||  Prandimet (repaglinide/metformin) / Novo Nordisk
    Unexpected side effect in the elderly () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_1337;    
    Currently in treatment with paracetamol due to catarrhal symptoms...It is usually triggered by drugs, including mirtazapine. A highly suspect is mandatory due to its letality.
  • ||||||||||  Prandimet (repaglinide/metformin) / Novo Nordisk
    Unexpected side effect in the elderly () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_1336;    
    Currently in treatment with paracetamol due to catarrhal symptoms...It is usually triggered by drugs, including mirtazapine. A highly suspect is mandatory due to its letality.
  • ||||||||||  Prandimet (repaglinide/metformin) / Novo Nordisk
    Unexpected side effect in the elderly () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_1335;    
    Currently in treatment with paracetamol due to catarrhal symptoms...It is usually triggered by drugs, including mirtazapine. A highly suspect is mandatory due to its letality.
  • ||||||||||  Prandimet (repaglinide/metformin) / Novo Nordisk
    Unexpected side effect in the elderly () -  Oct 17, 2022 - Abstract #EUSEM2022EUSEM_1334;    
    Currently in treatment with paracetamol due to catarrhal symptoms...It is usually triggered by drugs, including mirtazapine. A highly suspect is mandatory due to its letality.
  • ||||||||||  furosemide / Generic mfg.
    Not Your Typical Heart Failure: A Rare Case of Adult-Onset Bartter Syndrome () -  Oct 15, 2022 - Abstract #KIDNEYWEEK2022KIDNEY_WEEK_4326;    
    This gives BS a characteristic mechanism mimicking the loop diuretic, furosemide...While BS is underrepresented in adults, early recognition and understanding of this tubulopathies’ effects on heart failure management could reduce mortality and morbidity in this complicated patient population. KCl Response in Patient with BS
  • ||||||||||  midazolam hydrochloride / Generic mfg., furosemide / Generic mfg.
    Status Epilepticus With an AKI () -  Oct 15, 2022 - Abstract #KIDNEYWEEK2022KIDNEY_WEEK_4236;    
    She required a midazolam drip and was intubated for airway protection...In the absence of any other etiology for the AKI, a diagnosis of acute uric acid nephropathy was made and she was started on a bicarbonate drip along with furosemide to keep urine pH 6.5-7...Varghese et al showed that 20-25% cases which yielded no diagnosis on first urine microscopy, showed casts representing acute tubular injury on a second or third urine microscopy done 2-3 or 4-6 days later.(4) In our case, uric acid crystals were identified on a second urine microscopy while the first one was clear. Serial exams may be helpful in uncovering the cause of AKI which a single inspection may miss.
  • ||||||||||  furosemide / Generic mfg.
    Outpatient Recovery From Acute Kidney Injury Requiring Dialysis (ORKID): A Pilot Trial () -  Oct 15, 2022 - Abstract #KIDNEYWEEK2022KIDNEY_WEEK_4209;    
    P4
    Methods The ORKID trial (NCT05158153) is a single-center, single-arm pilot trial with target recruitment of 20 subjects with a primary aim to test the feasibility of providing a bundle of five interventions: chilled dialysate (35-36°C), high sodium dialysate (145 mmol/L), high dose diuretics (160 mg oral furosemide twice daily), high ultrafiltration hold threshold (SBP > 110 mmHg), and active dialysis weaning to patients with AKI-D being treated with outpatient hemodialysis...Conclusion Given that outpatient dialysis facilities are often located far from the hospitals where AKI-D occurred, dialysis-unit based recruitment rather than hospital-based recruitment may be superior for trials of outpatient AKI-D recovery. Whether this bundled intervention to decrease intradialytic hypotension and support AKI-D recovery is feasible in outpatient dialysis units remains unknown.
  • ||||||||||  furosemide / Generic mfg.
    Inadequate Diuresis due to AKI in Cardiorenal Syndrome Patients () -  Oct 15, 2022 - Abstract #KIDNEYWEEK2022KIDNEY_WEEK_4203;    
    It is a common myth that Lasix is nephrotoxic...Conclusion Though small sample size, study indicates that CRS patients are underdiuresed due to AKI leading to readmissions. Future prospective studies needed.