furosemide / Generic mfg. 
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  • ||||||||||  acetazolamide / Generic mfg., furosemide / Generic mfg., spironolactone / Generic mfg.
    Retrospective data, Review, Journal:  Diuretic combinations in critically ill patients with respiratory failure: A systematic review and meta-analysis. (Pubmed Central) -  Nov 5, 2022   
    Based on limited evidence, the addition of a second diuretic to a loop diuretic may promote diuresis and negative fluid balance in patients with respiratory failure, but only when using a thiazide. Further larger trials to evaluate the safety and efficacy of such interventions in patients with respiratory failure are required.
  • ||||||||||  furosemide / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  Characterization of the Efficacy of Furosemide Depending on Albumin Function (clinicaltrials.gov) -  Nov 3, 2022   
    P=N/A,  N=50, Completed, 
    Conclusion This study identified new signals of DI-AIHA using worldwide pharmacovigilance data, and confirmed the risk at the population level for some antibiotics, ibuprofen, acetaminophen and furosemide. Not yet recruiting --> Completed | Trial completion date: Dec 2023 --> Oct 2022 | Trial primary completion date: Dec 2023 --> Oct 2022
  • ||||||||||  cisplatin / Generic mfg., furosemide / Generic mfg., gentamicin sulfate / Generic mfg.
    Journal:  Intratympanic Administration of Dieckol Prevents Ototoxic Hearing Loss. (Pubmed Central) -  Nov 2, 2022   
    Not yet recruiting --> Completed | Trial completion date: Dec 2023 --> Oct 2022 | Trial primary completion date: Dec 2023 --> Oct 2022 Intratympanic local delivery of dieckol may be a safe and effective method to prevent ototoxic hearing loss.
  • ||||||||||  furosemide / Generic mfg., bumetanide / Generic mfg.
    Journal:  Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. (Pubmed Central) -  Oct 29, 2022   
    They also reveal two drug-binding sites located at the transmembrane and cytosolic carboxyl-terminal domains, respectively. Together, our findings enable us to delineate an inhibition mechanism that involves a coupled movement between the cytosolic and transmembrane domains of hNKCC1.
  • ||||||||||  furosemide / Generic mfg.
    Journal:  Evaluation of Newly Designed and Traditional Punches in Manufacturing of Scored ODTs. (Pubmed Central) -  Oct 28, 2022   
    In this work, the performance of the EBT punch was investigated vs. a ridged one for traditional breakable tablets (TBTs) using a furosemide powder formulation for orally disintegrating tablets (ODTs)...Less difficulty was found in splitting EBTs than TBTs (p < 0.05), and a larger number of tablets were properly broken into four parts. Thus, this study proved the usefulness of the EBT punch in overcoming drawbacks associated with divisible tablets.
  • ||||||||||  furosemide / Generic mfg.
    Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide (clinicaltrials.gov) -  Oct 27, 2022   
    P2,  N=17, Completed, 
    Thus, this study proved the usefulness of the EBT punch in overcoming drawbacks associated with divisible tablets. Recruiting --> Completed | N=100 --> 17 | Trial completion date: Jun 2024 --> Apr 2022 | Trial primary completion date: Nov 2023 --> Apr 2022
  • ||||||||||  Entresto (sacubitril/valsartan) / Novartis, ROVI Pharmaceuticals Laboratories
    A RARE PRESENTATION OF DILATED BIVENTRICULAR HEART FAILURE FROM GRAVES' DISEASE () -  Oct 26, 2022 - Abstract #ATA2022ATA_271;    
    He was initially managed with furosemide drip, propylthiouracil (PTU) and propranolol...Eventually, he was started on goal‐directed medical therapy for heart failure, which included metoprolol succinate, sacubitril‐valsartan, and spironolactone along with a wearable cardiac defibrillator on discharge...Reversible causes of dilated cardiomyopathy should be excluded during work up for cardiomyopathy. Overt congestive heart failure (CHF) due to hyperthyroidism is more likely to occur in individuals where hyperthyroidism is left untreated for a long period of time.
  • ||||||||||  furosemide / Generic mfg., spironolactone / Generic mfg.
    FREQUENT LARGE VOLUME PARACENTESIS IS NOT ASSOCIATED WITH DECLINE IN RENAL FUNCTION IN PATIENTS WITH PERSISTENT ASCITES () -  Oct 23, 2022 - Abstract #AASLD2022AASLD_1853;    
    There was a trend towards increased frequency of paracentesis and decrease in renal function at time of study completion versus baseline, but this did not reach statistical significance. Our findings support that repeated large volume paracentesis is a safe approach when patients are provided with appropriate volume replacement with albumin.