tobramycin topical / Generic mfg. 
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 0 Diseases   2 Trials   2 Trials   33 News 
  • ||||||||||  Gatiflox (gatifloxacin) / Orient Europharma
    Journal:  Corneal Deposits Following Combined Gatifloxacin and Prednisolone Therapy Post-Keratoplasty: A Report of a Rare Case. (Pubmed Central) -  Aug 12, 2024   
    Management included corneal scrapping and transition to topical tobramycin and propylene glycol eye drops, resulting in the resolution of deposits and improvement in vision. This case underscores the importance of vigilant monitoring and judicious use of topical medications to mitigate adverse effects in high-risk ophthalmic patients undergoing corneal procedures.
  • ||||||||||  vancomycin / Generic mfg., tobramycin topical / Generic mfg.
    Trial primary completion date:  Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: TOBRA (clinicaltrials.gov) -  Aug 3, 2023   
    P3,  N=1900, Recruiting, 
    There is a lack of consensus in the selection of perioperative antibiotic prophylaxis, thus a prospective study of the rates of infection with each strategy would be useful to inform guidelines. Trial primary completion date: May 2023 --> Sep 2023
  • ||||||||||  vancomycin / Generic mfg., gentamicin sulfate / Generic mfg.
    Enrollment open:  Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial (clinicaltrials.gov) -  Jul 5, 2023   
    P4,  N=484, Recruiting, 
    Trial primary completion date: May 2023 --> Sep 2023 Not yet recruiting --> Recruiting
  • ||||||||||  vancomycin / Generic mfg., gentamicin sulfate / Generic mfg.
    Trial initiation date:  Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial (clinicaltrials.gov) -  Apr 4, 2023   
    P4,  N=484, Not yet recruiting, 
    Not yet recruiting --> Recruiting Initiation date: Mar 2023 --> Jun 2023
  • ||||||||||  vancomycin / Generic mfg., gentamicin sulfate / Generic mfg.
    Trial initiation date:  Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial (clinicaltrials.gov) -  Dec 28, 2022   
    P4,  N=484, Not yet recruiting, 
    Initiation date: Mar 2023 --> Jun 2023 Initiation date: Dec 2022 --> Mar 2023
  • ||||||||||  Trial completion, Enrollment change:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Apr 20, 2022   
    P1/2,  N=19, Completed, 
    There is no significant benefit of adding an oral antibiotic with the topical antibiotic steroid in the treatment of uncomplicated AOE limited to the ear canal in immunocompetent patients. Recruiting --> Completed | N=40 --> 19
  • ||||||||||  tobramycin topical / Generic mfg.
    Clinical, Observational data, Journal:  Off-label drug use in neonates and infants in Spain: a five-year observational study. (Pubmed Central) -  Mar 26, 2022   
    Off-label use of drugs remains as an important public health concern, especially for neonates and infants up to 1 year, who receive the greatest proportion of off-label prescriptions. The evidence-based off-label prescription is a widespread practice that has shown a stable trend during the 5-year study period providing also a certain extent of flexibility to paediatricians in some therapeutic decisions.
  • ||||||||||  vancomycin / Generic mfg., tobramycin topical / Generic mfg.
    Journal:  Tobramycin Blood Levels after Local Antibiotic Treatment of Bone and Soft Tissue Infection. (Pubmed Central) -  Mar 26, 2022   
    All systemic tobramycin levels were <2 mcg/mL at 72 h, and the resulting rate of AKI was 12% (7/58). In conclusion, local tobramycin antibiotic delivery using PMMA, CS, or both remains a safe and effective modality in the treatment of osteomyelitis as long as the surgeon is aware of its possible nephrotoxic effect.
  • ||||||||||  tobramycin topical / Generic mfg.
    CHALLENGES IN THE MANAGEMENT OF FUNGAL KERATITIS – CASE REPORT (Track 1) -  Feb 8, 2022 - Abstract #ESCRSWM2022ESCRS_WM_276;    
    Microbial specimens were collected, and the patient started on topical ciprofloxacin ointment and tobramycin and ceftazidime eye drops...Fungus identification using microbiological techniques is essential for an early diagnosis, which allows the timely treatment and avoids irreversible complications. We report a case that documents the effectiveness of topical iodine povidone as an adjunctive treatment for refractory Fusarium keratitis, resistant to other triazoles and conventional antifungals.
  • ||||||||||  Zylet (loteprednol etabonate/tobramycin ophthalmic suspension) / Bausch Health
    Review, Journal:  Review of Loteprednol Etabonate 0.5%/Tobramycin 0.3% in the Treatment of Blepharokeratoconjunctivitis. (Pubmed Central) -  Oct 30, 2021   
    Results of published studies indicate that LE/T is effective in the treatment of blepharokeratoconjunctivitis in adults, with similar efficacy as dexamethasone 0.1%/tobramycin 0.3%, but is associated with a lower risk of clinically significant increases in intraocular pressure as demonstrated in both efficacy and safety studies and studies with healthy volunteers...Separately, tobramycin demonstrated potent in vitro activity against most bacterial species associated with blepharitis. In conclusion, published data demonstrate the utility of LE/T for the treatment of the various clinical manifestations of blepharokeratoconjunctivitis in adults.
  • ||||||||||  vancomycin / Generic mfg., tobramycin topical / Generic mfg.
    Enrollment open, Trial completion date, Trial primary completion date:  Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: TOBRA (clinicaltrials.gov) -  Jul 1, 2021   
    P3,  N=1900, Recruiting, 
    In conclusion, published data demonstrate the utility of LE/T for the treatment of the various clinical manifestations of blepharokeratoconjunctivitis in adults. Not yet recruiting --> Recruiting | Trial completion date: Dec 2022 --> May 2024 | Trial primary completion date: Dec 2022 --> May 2023
  • ||||||||||  Trial completion date, Trial primary completion date:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Jan 8, 2021   
    P1/2,  N=40, Recruiting, 
    Initiation date: Mar 2021 --> Jun 2021 Trial completion date: Jul 2021 --> Jul 2022 | Trial primary completion date: Dec 2020 --> Dec 2021
  • ||||||||||  Trial completion date, Trial primary completion date:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Jan 3, 2020   
    P1/2,  N=40, Recruiting, 
    Initiation date: Oct 2020 --> Jan 2021 Trial completion date: Jul 2020 --> Jul 2021 | Trial primary completion date: Dec 2019 --> Dec 2020
  • ||||||||||  Trial completion date, Trial primary completion date:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Aug 14, 2019   
    P1/2,  N=40, Recruiting, 
    Trial completion date: Jul 2020 --> Jul 2021 | Trial primary completion date: Dec 2019 --> Dec 2020 Trial completion date: Jul 2019 --> Jul 2020 | Trial primary completion date: Jul 2019 --> Dec 2019
  • ||||||||||  Enrollment open:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Sep 26, 2018   
    P1/2,  N=40, Recruiting, 
    Trial completion date: Jul 2019 --> Jul 2020 | Trial primary completion date: Jul 2019 --> Dec 2019 Not yet recruiting --> Recruiting