Zoenasa (mesalazine & N acetylcysteine) News

|||||||||| Zoenasa (mesalazine & N acetylcysteine) / Altheus
Journal: Optimising the performance of frontline implementers engaged in the NTD programme in Nigeria: lessons for strengthening community health systems for universal health coverage. (Pubmed Central) - Sep 19, 2020
It is critical to strengthen the collaboration between health systems and communities so that together they can jointly provide the necessary support for frontline implementers to deliver health for all. This research presents additional evidence that involving frontline implementers in the planning and implementation of health interventions through regular feedback before, during and after implementation has the potential to strengthen health outcomes.

|||||||||| Zoenasa (mesalazine & N acetylcysteine) / Altheus
[VIRTUAL] Survey of an online pulmonary wellness & rehabilitation program in people with chronic respiratory disease (Pre-congress content) - Jul 15, 2020 - Abstract #ERS2020ERS_3612;
Participants increased QoL without SAEs and the program was rated feasible by participants. A multi-center, sufficiently powered online study of the intervention is planned to test safety and efficacy.

|||||||||| Zoenasa (mesalazine & N acetylcysteine) / Altheus
[VIRTUAL] Safety, Efficacy and Impact on Quality of Life of a 42-Day Online Pulmonary Wellness and Rehabilitation Program in People Living with Chronic Respiratory Disease (ATS 2020 Virtual) - Jul 6, 2020 - Abstract #ATSI2020ATS-I_3564;
This study demonstrates that Pulmonary Wellness Online improves QoL across all age groups and gender. The results obtained from this study should be confirmed with a large, multi-center study with more patients and additional physiological parameters collected including spirometry, heart rate (HR), blood pressure (BP), oxygen saturation (sPO2%), body weight, and sleep patterns.

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Safety, Efficacy and Impact on Quality of Life of a 42-Day Online Pulmonary Wellness and Rehabilitation Program in People Living with Chronic Respiratory Disease (PENNSYLVANIA CONVENTION CENTER, Hall D-E (200 Level), Area A) - Mar 15, 2020 - Abstract #ATS2020ATS_5939;
This study demonstrates that Pulmonary Wellness Online improves QoL across all age groups and gender. The results obtained from this study should be confirmed with a large, multi-center study with more patients and additional physiological parameters collected including spirometry, heart rate (HR), blood pressure (BP), oxygen saturation (sPO2%), body weight, and sleep patterns.

|||||||||| Zoenasa (mesalazine & N acetylcysteine) / Altheus
Clinical, Journal: Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial - a study protocol of a randomised controlled trial. (Pubmed Central) - Dec 6, 2019
If successful, peer support may be proposed, adopted and implemented as a strategy to encourage cancer survivors to maintain exercise beyond the duration of a short-term, supervised intervention. A peer support-exercise model has the long-term potential to reduce comorbidities, improve physical and mental wellbeing, and significantly reduce the burden of disease in cancer survivors.

|||||||||| Zoenasa (mesalazine & N acetylcysteine) / Altheus
Observational data, Journal: The relationship between pain with walking and self-rated health 12 months following total knee arthroplasty: a longitudinal study. (Pubmed Central) - Feb 23, 2018
In patients whose walking ability decreases over time, clinicians need to assess for unreleaved pain and decreases in SRH. Additional research is needed on interventions to improve walking ability and SRH.

||||||||||  Zoenasa (mesalazine & N acetylcysteine) / Altheus
Enrollment closed:  Study of the Safety and Efficacy of Zoenasa® Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis (clinicaltrials.gov) -  Jan 6, 2014
P2, N=120, Active, not recruiting,  Sponsor: Altheus Therapeutics, Inc.
Additional research is needed on interventions to improve walking ability and SRH. Recruiting --> Active, not recruiting

||||||||||  Zoenasa (mesalazine & N acetylcysteine) / Altheus
New P2 trial:  Study of the Safety and Efficacy of Zoenasa® Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis (clinicaltrials.gov) -  Apr 25, 2012
P2, N=120, Active, not recruiting,  Sponsor: Altheus Therapeutics, Inc.



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