| Daflon (micronized purified flavonoid fraction) / Servier |
2007-001947-23: A multicenter, randomized, parallel patients’ group, comparative clinical trial for the assessement of efficacy and safety of Pelethrocin®/HELP 500 mg (generic diosmin & hesperidin MPFF) versus Daflon®/Servier 500 mg (original diosmin & hesperidin MPFF) in the treatment of chronic venous insufficiency patients (a therapeutic equivalence trial). |
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| Ongoing | 4 | 136 | Europe | Pelethrocin, Daflon, Pelethrocin, Daflon, Pelethrocin, Daflon | HELP Pharmaceuticals S.A. | Chronic Venous Insufficiency | | | | |
| Not yet recruiting | 4 | 120 | NA | Medtronic® Concerto® detachable coil system, concerto detachable coil system, sclerosis, Foam sclerosis with polidocanol 2%, Diosmin / Hesperidin, daflon, Ibuprofen 400 mg, Nsaid | Hospital de ClÃnicas Dr. Manuel Quintela, University of the Republic, Uruguay, Centro Cardiovascular Universitario, Centro Hospitalario Pereyra Rossell | Pelvic Congestive Syndrome, Pelvic Varices, Venous Disease | 07/22 | 10/22 | | |
NCT06184438: Randomized Control Trial of Micronized Purified Flavonoid Fraction for Post Operative Treatment in Anal Fistula Surgery |
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| Recruiting | 4 | 150 | RoW | Micronized purified flavonoid fraction(Daflon 1000mg), diosmin, hesperidin, Placebo, Control group | Taipei Medical University Shuang Ho Hospital | Anal Fistula | 12/25 | 03/26 | | |
NCT06083935: Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome |
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| Not yet recruiting | 4 | 120 | NA | Daflon, Combined oral contraceptive, Metformin | Ain Shams University | Poly Cystic Ovary Syndrome | 08/24 | 12/24 | | |
NCT06546111: Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection |
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| Recruiting | 1/2 | 46 | RoW | Placebo, Daflon | Sadat City University | Helicobacter Pylori Infection | 10/25 | 10/26 | | |
| Not yet recruiting | N/A | 2000 | NA | Radiofrequency ablation using Closure fast, Laserablation using laser fiber, Aethoxysclerol, polidocanol, Daflon, Venoruton, Antistax, Compression stocking | Universitaire Ziekenhuizen KU Leuven | Chronic Venous Disease | 11/26 | 05/27 | | |
NCT06560294: Glue Embolization vs Conservative Treatment for Pelvic Congestion Syndrome |
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| Recruiting | N/A | 40 | RoW | Micronized purified flavonoid fraction (Daflon ®), Glue embolization | Tanta University | Glue Embolization, Pelvic Congestion Syndrome | 12/24 | 12/24 | | |
NCT05113420: The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations |
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| Recruiting | N/A | 1000 | RoW | Detralex, Troxevasin | Center for Vascular Pathology, Moscow | Drug Effect, Children, Only, Vascular Malformations, Surgery | 11/21 | 09/22 | | |
