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0 Diseases |  |
21 Trials |
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21 Trials |  |
322 News |  |
| «123456» |
- || pethidine / Samaritan
Clinical, Journal: The Effect of Reducing the Fasting Time on Postoperative Pain in Orthopaedic Patients: A Randomized Controlled Trial. (Pubmed Central) - Aug 24, 2021
The pain intensity in the patients with shortened fasting time was lower, but it was not statistically significant. Moreover, reducing fasting time by using carbohydrate significantly reduced the use of analgesics.
- | pethidine / Samaritan
Journal: Sedation with fentanyl and midazolam without oropharyngeal anesthesia compared with sedation with pethidine and midazolam with oropharyngeal anesthesia in ultrathin bronchoscopy for peripheral lung lesions. (Pubmed Central) - Aug 22, 2021
Moreover, reducing fasting time by using carbohydrate significantly reduced the use of analgesics. Our findings indicate the advantages of sedation with fentanyl and midazolam without oropharyngeal anesthesia for ultrathin bronchoscopy through nasal intubation.
- || tamsulosin / Generic mfg., tadalafil / Generic mfg.
Clinical, Journal: Efficacy of tamsulosin versus tadalafil as medical expulsive therapy on stone expulsion in patients with distal ureteral stones: A randomized double-blind clinical trial. (Pubmed Central) - Aug 11, 2021
Our findings indicate the advantages of sedation with fentanyl and midazolam without oropharyngeal anesthesia for ultrathin bronchoscopy through nasal intubation. Tamsulosin as medical expulsive therapy is more effective for distal ureteric stones with less need for analgesics and less stone expulsion time than tadalafil.
- pethidine / Samaritan
[VIRTUAL] Randomized Single - Blind Comparative Study of Midazolam Plus Pethidine Combination and Midazolam During Bronchoscopy (ePoster Hall) - Aug 9, 2021 - Abstract #IASLCWCLC2021IASLC_WCLC_307;
Conclusion Our study has shown the efficacy and safety of the combination of midazolam plus pethidine method in the sedation for bronchoscopy. This combination method can improve tolerance of bronchoscopy.
- | Olinvyk (oliceridine) / Trevena, Jiangsu NHWA Pharma, pethidine / Samaritan
Journal: A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity. (Pubmed Central) - Jul 31, 2021
DS21980956 had potent analgesic activity in the mouse acetic acid writhing test or tail flick test without agonistic activity at the µ opioid receptor (MOR). The mechanism of analgesic action of DS21980956 was considered to differ from a biased ligand, for example, TRV-130 (3, oliceridine).
- || pethidine / Samaritan
Clinical, Journal: The Effects of Acupressure on Post-Cesarean Pain and Analgesic Consumption: A Randomized Single-Blinded Placebo-Controlled Study. (Pubmed Central) - Jul 30, 2021
P=N/A
Acupressure is an effective method for reducing post-cesarean pain and analgesic consumption. Clinical trial registration: ClinicalTrials.gov: NCT04337801.
- pethidine / Samaritan
[VIRTUAL] Non intubated surgery in empyema thoracis () - Jul 29, 2021 - Abstract #ERS2021ERS_2947;
2. The procedure is not only technically feasible and cost-effective, but may be also a safe and less invasive alternative.
- | pethidine / Samaritan
Journal: Preoperative ankle block for postoperative analgesia in foot surgery. (Pubmed Central) - Jul 28, 2021
It reduced the time to mobilization without a delay in hospital discharge. It is concluded that the routine administration of AB before GA may be an effective and simple method for pain relief after foot surgery.
- || Dynastat (parecoxib) / Pfizer
Clinical, Journal: Effects of parecoxib after pancreaticoduodenectomy: A single center randomized controlled trial. (Pubmed Central) - Jul 8, 2021
Parecoxib effectively controls pain after PD. Prophylactic analgesia using parecoxib for up to 5 days after PD is safe, feasible, and can provide the same optimal pain control as opioids without adverse effects.
- || pethidine / Samaritan
Clinical, Journal: Effect of nurse-supported care on pain management in women undergoing caesarean delivery: a comparative study. (Pubmed Central) - Jul 7, 2021
Nurse-supported care provided better analgesia than usual care in women who had undergone caesarean delivery. A multicentre study is needed to explore the types, duration, and repeatability of the effects of nurse supportive care on pain perception and duration of hospital stay after caesarean delivery.
- || pethidine / Samaritan
Clinical, Journal: The Analgesic Efficacy of Erector Spinae Plane Blocks in Patients Undergoing Posterior Lumbar Spinal Surgery for Lumbar Fracture. (Pubmed Central) - Jul 7, 2021
PCA combined with lumbar ESP blocks provided superior postoperative analgesia for patients with lumbar spinal fractures treated with posterior internal fixation. Lumbar ESP blocks decreased postoperative opioid consumption and the incidence of postoperative nausea and vomiting, thereby enhancing postoperative recovery.
- || Innohep (tinzaparin) / LEO Pharma, pethidine / Samaritan
Review, Journal: Commonly used agent for acute pain management of sickle cell anemia in Saudi Emergency Department: A narrative review. (Pubmed Central) - Jul 2, 2021
However, there was no recommendation for a certain agent to be prescribed. We recommend conducting further clinical randomized-controlled trials.
- | pethidine / Samaritan
Journal: The Effect of Pethidine Analgesia on Labor Duration and Maternal-Fetal Outcomes. (Pubmed Central) - Jun 30, 2021
Pethidine significantly reduces active phase of labor duration, has a favorable analgesic effect in treating labor pain and is not associated with serious maternal or neonatal complications. It is therefore considered an acceptable agent for use during active phase of labor.
- | pethidine / Samaritan
Retrospective data, Journal: Oxygen toxicity seizure mimics. (Pubmed Central) - Jun 30, 2021
This creates scope for misdiagnosis, with potential for consequent morbidity and mortality. A pragmatic approach is necessary to any patient exhibiting seizure-like activity during HBOT, with suspicion for other underlying pathologies.
- ketorolac / Generic mfg., lorazepam / Generic mfg.
[VIRTUAL] Much further than a Kidney Stone, a Case Report () - Jun 29, 2021 - Abstract #IASP2021IASP_883;
The physical visceral pain for his kidney condition, which led him to develop an opiate addiction. The opiate addiction includes the withdrawal syndrome and the pain represents a common symptom.
- ketamine / Generic mfg.
[VIRTUAL] Use of Virtual Reality Glasses to Reduce Child Pain and Fear during Painful Medical Procedures in Children with Physical Disabilities in Uganda: A feasibility study () - Jun 29, 2021 - Abstract #IASP2021IASP_444;
Acceptability of VR glasses in children in our study overall was high; positive reactions were gathered from children, parents, and nurses. The use of VR glasses may offer an acceptable and effective pain and fear reduction method in resource-constrained settings and should be further explored in a randomized control trial.
- || ketorolac / Generic mfg.
Clinical, Journal: An Innovative Pain Control Method Using Peripheral Nerve Block and Patient-Controlled Analgesia With Ketorolac After Bone Surgery in the Ankle Area: A Prospective Study. (Pubmed Central) - Jun 26, 2021
An average of 0.75 and 11.40 mg pethidine per patient was used in groups A and B, respectively, for 3 days. We concluded that the combined use of ultrasound-guided PNB and PCA with ketorolac can be an effective postoperative method of pain control that can reduce opioid usage.
- || Dynastat (parecoxib) / Pfizer, pethidine / Samaritan
Clinical, Journal, Monotherapy: Comparison of analgesic efficacy of acetaminophen monotherapy versus acetaminophen combinations with either pethidine or parecoxib in patients undergoing laparoscopic cholecystectomy: a randomized prospective study. (Pubmed Central) - Jun 26, 2021
In contrast, patients in group C (acetaminophen monotherapy) had higher NRS scores, compared to both patients in groups A (p<0.01) and B (p<0.01). Conclusion This study confirms the notion of a significant opioid-sparing effect of parecoxib in postoperative pain management after laparoscopic cholecystectomy.
- || pethidine / Samaritan
Clinical, Retrospective data, Journal: The efficacy of the ON-Q elastomeric pump system in post-thoracotomy acute pain control. (Pubmed Central) - May 28, 2021
The primary outcomes were postoperative acute pain scores on the numeric rating scale and postoperative rescue opioid consumption for 72 hours following surgery reported as pethidine equivalents...In Group LA, postoperative length of hospital stay was significantly shorter (5.8 ± 2.1 days vs. 8.0 ± 3.1 days; p = 0.034), drug costs (95.24 vs. 160.08 Euro; p = 0.023) and total hospital costs were lower (434.26 vs. 685.75 Euro; p = 0.014) than Group IVT. We believe that continuous local anesthetic infusion to the incision site in addition to systemic analgesic treatment for multimodal acute pain management after thoracotomy is an effective and safe method.
- | pethidine / Samaritan
Journal: Palliative Care Quiz for Nurses-Indonesian Version (PCQN-I): A Cross-cultural Adaptation, Validity, and Reliability Study. (Pubmed Central) - May 27, 2021
An expert committee revised the words in Item 4 from "adjuvant therapies" to "adjuvant therapies/additional therapies," in Item 5 from "bowel regimen" to "gastrointestinal therapies," and Item 16 from "Demerol" to "Pethidine" based on the Indonesian context...The PCQN-I is a valid and reliable instrument for assessing palliative care knowledge among PHC providers. Further research is warranted to examine its reliability in different clinical settings.
- | pethidine / Samaritan
Retrospective data, Journal: Impact of obesity in colorectal endoscopic submucosal dissection: single-center retrospective cohort study. (Pubmed Central) - May 15, 2021
This study showed that colorectal ESD could be performed safely and effectively in obese patients. However, ESD in obese patients requires attention, particularly to changes in respiratory conditions.
- | Observational data, Journal: Utilization of Pre-Anesthetic Medications for Major Surgical Procedures at a Tertiary Care Center: A Descriptive Cross-sectional Study. (Pubmed Central) - May 14, 2021
The most commonly administered pre-anesthetic drugs were midazolam, pethidine, glycopyrrolate, and ondansetron. The incidence of postoperative nausea and vomiting the patient within 24 hours after surgery was significantly very low.
- || pethidine / Samaritan
Clinical, Journal: Effect of COVID-19 on delivery plans and postnatal depression scores of pregnant women. (Pubmed Central) - May 7, 2021
This was coupled with a drop in the delivery rate at our public hospital. Suspension of childbirth companionship might have altered the methods of intrapartum pain relief and the overall pregnancy experience.
- | pethidine / Samaritan
Journal: Determination of pethidine of abuse and relevant metabolite norpethidine in urine by ultra-performance liquid chromatography-tandem mass spectrometry. (Pubmed Central) - May 5, 2021
Lower limits of quantitation were 9 ng/mL for both pethidine and norpethidine. The developed method was successfully applied for the determination of both analytes in the real samples.
- || pethidine / Samaritan
Clinical, Journal: Comparison of Pain Score and Complications Following Acetaminophen and Pethidine Injection During Vaginal Delivery: A Double-blind Clinical Trial. (Pubmed Central) - May 4, 2021
The mean one and five minutes Apgar scores were significantly higher in the acetaminophen group. Intravenous acetaminophen led to fewer maternal complications than pethidine, especially during the first 15 minutes after injection and fewer neonatal complications, especially in the Apgar score.
- | ketamine / Generic mfg., gabapentin / Generic mfg.
Retrospective data, Journal: Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study. (Pubmed Central) - Apr 28, 2021
Intravenous acetaminophen led to fewer maternal complications than pethidine, especially during the first 15 minutes after injection and fewer neonatal complications, especially in the Apgar score. We identified modifiable factors associated with postoperative delirium incidence among patients undergoing hip fracture repair surgery.
- || paracetamol / Generic mfg.
Clinical, Journal: Efficacy and safety of intravenous paracetamol in management of labour pains in a low resource setting: a randomized clinical trial. (Pubmed Central) - Apr 28, 2021
P=N/A
Intravenous paracetamol as labour analgesia is effective, safe, inexpensive, available and with no maternal or fetal side effects as compared to Pethidine. Paracetamol needs to have more chance in comparison to other forms as a labour pain analgesia, especially in our communities.
- | pethidine / Samaritan
Journal: Effect of analgesia with pethidine during labour on false positivity of newborn hearing screening test. (Pubmed Central) - Apr 23, 2021
P=N/A
However, it may have neonatal effects after the delivery, causing false positivity in newborn hearing screening tests. The results of this study support the opinion that the OAE test should be performed in postpartum later dates in order to increase OAE passing rates and minimize costs and parents' concerns.
- || pethidine / Samaritan
Clinical, Journal, Head-to-Head: A randomized double-blinded non-inferiority trial comparing fentanyl and midazolam with pethidine and diazepam for pain relief during oocyte retrieval. (Pubmed Central) - Apr 13, 2021
The results of this study support the opinion that the OAE test should be performed in postpartum later dates in order to increase OAE passing rates and minimize costs and parents' concerns. The fentanyl and midazolam group had significantly lower vaginal and abdominal pain levels during oocyte retrieval than the pethidine and diazepam group.
- | morphine/oxycodone (Q8011) / QRxPharma, pethidine / Samaritan
Journal: Ten Years of Strong Opioid Analgesics Consumption in Malaysia and Other Southeast Asian Countries. (Pubmed Central) - Apr 10, 2021
Growing trends of strong opioids consumption in all five Southeast Asian countries demonstrated in this study may indicate improved access to opioid analgesics in these countries. Given the increasing trends, it is important to ensure that the utilization of opioids is according to the guideline to prevent the negative consequences of opioids particularly when used in chronic non-cancer pain.
- | pethidine / Samaritan
Retrospective data, Journal: Continuous wound infiltration of ropivacaine for reducing of postoperative pain after anterior lumbar fusion surgery: a clinical retrospective comparative study. (Pubmed Central) - Apr 1, 2021
Patients who used the On-Q system performed more diverse activity and achieved earlier ambulation than those in the control group. Continuous wound infiltration with ropivacaine using an On-Q system may be effective for controlling postoperative pain after ALIF surgery.
- | pethidine / Samaritan
Journal: Impact of opioid free anaesthesia in bariatric surgery (Pubmed Central) - Mar 27, 2021
The OFA has proved to be secure and achieves optimum pain control. In the reconverted cases, good control of the parameters opens up the possibility of its use in more painful surgeries.
- || midazolam hydrochloride / Generic mfg.
Clinical, Journal: Risk Factors for Prolonged Hospital Stay after Endoscopy. (Pubmed Central) - Mar 17, 2021
Age (odds ratio [OR], 1.025; 95% confidence interval [CI], 1.014-1.036), female sex (OR, 1.657; 95% CI, 1.220-2.249), and midazolam dose (OR, 1.019; 95% CI, 1.013-1.026) were independently associated with prolonged hospital stay after esophagogastroduodenoscopy, with similar results for colonoscopy. Old age, female sex, and midazolam dose were independent risk factors for prolonged hospital stay after endoscopy.
- || pethidine / Samaritan
Stop stocking oral opioids in the ED, much like we did with Pethidine. (Twitter) - Mar 12, 2021
- | pethidine / Samaritan
Journal: Comparison of Thoracic Epidural and Intravenous Analgesia from the Perspective of Recovery of Respiratory Function in the Early Post-Thoracotomy Period in Lung Cancer Surgery. (Pubmed Central) - Mar 2, 2021
Old age, female sex, and midazolam dose were independent risk factors for prolonged hospital stay after endoscopy. We believe that TEA is advantageous over IVA with alteration of respiratory volumes during the early postoperative period.
- | pethidine / Samaritan
Journal: Compliance of private pharmacies in Uganda with controlled prescription drugs regulations: a mixed-methods study. (Pubmed Central) - Feb 27, 2021
Training and regulatory audits increased compliance in stock control but not dispensing. Expansion of training and audits to more pharmacies and/or incentives for compliance are necessary.
- || pethidine / Samaritan
Clinical, Journal: Resistin Gene Polymorphism Is an Influencing Factor of Postoperative Pain for Chinese Patients. (Pubmed Central) - Feb 27, 2021
Expansion of training and audits to more pharmacies and/or incentives for compliance are necessary. RETN rs3745367 was associated with postoperative average pain intensity, OPRM1 rs2075572 and rs9322447 may influence postoperative maximal pain intensity.
- midazolam hydrochloride / Generic mfg.
[VIRTUAL] Implementation of Aldrete's scoring system significantly reduces recovery time after procedural sedation by more than 20%. () - Feb 23, 2021 - Abstract #BWG2021BWG_87;
No complications related to earlier discharge from the recovery area were observed. Conclusions Implementation of Aldrete's scoring system after procedural sedation and analgesia significantly reduces the time spent at the recovery area without increasing complication rate.
- || pethidine / Samaritan
Clinical, Journal: Effectiveness of breathing exercises, foot reflexology and back massage (BRM) on labour pain, anxiety, duration, satisfaction, stress hormones and newborn outcomes among primigravidae during the first stage of labour in Saudi Arabia: a study protocol for a randomised controlled trial. (Pubmed Central) - Feb 16, 2021
Eligible and consenting patients will be randomly allocated to the intervention or the control group stratified by intramuscular pethidine use...Results from this trial will be presented at regional, national and international conferences and published in indexed journals. ISRCTN87414969, registered 3 May 2019.
- | pethidine / Samaritan
Retrospective data, Journal: Anesthesia for Cesarean Section: Retrospective Comparative Study. (Pubmed Central) - Feb 11, 2021
Satisfaction was higher with epidural anesthesia. Retrospective and single centered.
- | pethidine / Samaritan
New trial: Efficacy and Safety of Intravenous Paracetamol in Manament of Labour Pain (clinicaltrials.gov) - Feb 9, 2021
P=N/A, N=96, Completed, Sponsor: Menoufia University
- | ketorolac / Generic mfg.
Journal: Compatibility of acetaminophen with central nervous system medications during simulated Y-site injection. (Pubmed Central) - Feb 9, 2021
Retrospective and single centered. Nine of 15 common CNS medications in critical care tested with acetaminophen were physically incompatible for 24 hours.
- | pethidine / Samaritan Pharma
Trial completion date, Trial primary completion date: CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) (clinicaltrials.gov) - Feb 9, 2021
P2/3, N=1326, Recruiting, Sponsor: KK Women's and Children's Hospital
Nine of 15 common CNS medications in critical care tested with acetaminophen were physically incompatible for 24 hours. Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: May 2021 --> Aug 2021
- | pethidine / Samaritan
New trial: Erector Spinae Block Versus Thoracic Paravertebral Block for Postoperative Pain Control After Open Nephrectomy (clinicaltrials.gov) - Jan 22, 2021
P=N/A, N=45, Not yet recruiting, Sponsor: Cairo University
- || Retrospective data, Review, Journal: Pharmacological strategies to prevent postoperative delirium: a systematic review and network meta-analysis. (Pubmed Central) - Jan 15, 2021
The combination of propofol and acetaminophen and the combination of ketamine and dexmedetomidine seemed to be effective in preventing POD. However, further studies are needed to determine the optimal pharmacological intervention to prevent POD.
- pethidine / Samaritan
[VIRTUAL] Intravenous morphine achieved a more sustained pain response during acute pain crisis in adult sickle cell disease patients compared to intramuscular pethidine () - Jan 5, 2021 - Abstract #BSHI2020BSH-I_71;
Table 7. Comparison of analgesia with duration for sustained response (n = 82) *Mann–Whitney U test.
- | pethidine / Samaritan
New P3 trial: Sedation Techniques for Outpatient Colonoscopy (clinicaltrials.gov) - Dec 28, 2020
P3, N=105, Completed, Sponsor: Universiti Kebangsaan Malaysia Medical Centre
- || pethidine / Samaritan
Clinical, Journal: The Effect of Intravesical Diluted Bupivacaine on Catheter-Related Bladder Discomfort in Young and Middle-Aged Male Patients During Postanaesthetic Recovery. (Pubmed Central) - Dec 17, 2020
It may be concluded that intravesical diluted bupivacaine can significantly decrease the incidence and severity of CRBD in young male patients during recovery from anaesthesia. Therefore, the use of this method is highly recommended.
- || pethidine / Samaritan
Clinical, Journal: Prevalence and Risk Factors for Acute Postoperative Pain After Elective Orthopedic and General Surgery at a Tertiary Referral Hospital in Tanzania. (Pubmed Central) - Nov 28, 2020
It reflects the need for adequate postoperative analgesia, especially in low- and middle-income countries. Further research identifying risk factors in larger cohorts can be performed if adequate analgesia is given.
- | pethidine / Samaritan
Journal: Towards exhaustive electromembrane extraction under stagnant conditions. (Pubmed Central) - Nov 26, 2020
Stagnant EME was evaluated in combination with liquid chromatography-mass spectrometry (LC-MS) as a highly specific instrumental method, and provided evaluation data on methadone from blood samples in accordance with regulatory requirements (LOD: 0.4 ng/mL, LOQ: 1.4 ng/mL, RSD: 6-20%). This work has improved upon the design of stagnant EME, moving it further towards a viable in-field operation device.