Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie 
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 19 Diseases   1 Trial   1 Trial   3388 News 


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  • ||||||||||  Humira (adalimumab) / Eisai, AbbVie
    Antibiotic resistances in hidradenitis suppurative patients treated with adalimumab (Room 2) -  Feb 2, 2023 - Abstract #EHSF2023EHSF_181;    
    Otherwise, an empirical choice should be made. Future prospective studies on AB resistance patterns, microbiome characteristics and their relationships with different HS therapies, including AB, immunomodulatory drugs and anti-TNF-a targeted therapies, are required.
  • ||||||||||  Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie
    Journal:  Colonization by ceftazidime/avibactam-resistant KPC-producing Klebsiella pneumoniae following therapy in critically ill patients. (Pubmed Central) -  Jan 31, 2023   
    Future prospective studies on AB resistance patterns, microbiome characteristics and their relationships with different HS therapies, including AB, immunomodulatory drugs and anti-TNF-a targeted therapies, are required. Antimicrobial exposure induce higher incidence of CAZ-AVI -resistance development in blood and respiratory tract than in rectum (6.7% vs 3.3%) of CAZ-AVI-treated patients and genome analysis showed that resistance was associated to mutated bla variants.