memantine ER / Generic mfg. 
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  • ||||||||||  memantine ER / Generic mfg.
    Phase classification:  NTS-WBRT in Brain Metastases (clinicaltrials.gov) -  Mar 21, 2024   
    P2,  N=41, Recruiting, 
    Phase classification: P=N/A --> P2
  • ||||||||||  memantine ER / Generic mfg.
    Phase classification, Enrollment change:  NTS-WBRT in Brain Metastases (clinicaltrials.gov) -  Mar 18, 2024   
    P=N/A,  N=41, Recruiting, 
    Phase classification: P=N/A --> P2 Phase classification: P2 --> P=N/A | N=100 --> 41
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Feb 2, 2023   
    P1,  N=20, Active, not recruiting, 
    Phase classification: P2 --> P=N/A | N=100 --> 41 Trial completion date: Dec 2022 --> Dec 2023 | Trial primary completion date: Dec 2022 --> Dec 2023
  • ||||||||||  memantine ER / Generic mfg.
    Enrollment open:  NTS-WBRT in Brain Metastases (clinicaltrials.gov) -  Apr 8, 2022   
    P2,  N=100, Recruiting, 
    Trial completion date: Dec 2022 --> Dec 2023 | Trial primary completion date: Dec 2022 --> Dec 2023 Not yet recruiting --> Recruiting
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date, Combination therapy:  Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy (clinicaltrials.gov) -  Apr 6, 2022   
    P=N/A,  N=20, Completed, 
    Not yet recruiting --> Recruiting Trial completion date: Aug 2019 --> Apr 2021 | Trial primary completion date: Aug 2017 --> Apr 2021
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion, Combination therapy:  Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy (clinicaltrials.gov) -  Mar 10, 2022   
    P=N/A,  N=20, Completed, 
    Trial completion date: Aug 2019 --> Apr 2021 | Trial primary completion date: Aug 2017 --> Apr 2021 Recruiting --> Completed
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Feb 7, 2022   
    P1,  N=20, Active, not recruiting, 
    Recruiting --> Completed Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2021 --> Dec 2022
  • ||||||||||  memantine ER / Generic mfg.
    New P2 trial:  NTS-WBRT in Brain Metastases (clinicaltrials.gov) -  Aug 18, 2021   
    P2,  N=100, Not yet recruiting, 
  • ||||||||||  memantine ER / Generic mfg.
    Enrollment closed:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Aug 6, 2021   
    P1,  N=20, Active, not recruiting, 
    Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2021 --> Dec 2022 Recruiting --> Active, not recruiting
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Feb 3, 2021   
    P1,  N=20, Recruiting, 
    Recruiting --> Active, not recruiting Trial completion date: Dec 2020 --> Dec 2021 | Trial primary completion date: Jul 2020 --> Dec 2021
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date, Combination therapy:  Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy (clinicaltrials.gov) -  Nov 13, 2020   
    P=N/A,  N=20, Recruiting, 
    Trial completion date: Dec 2020 --> Dec 2021 | Trial primary completion date: Jul 2020 --> Dec 2021 Trial completion date: Dec 2019 --> Dec 2022 | Trial primary completion date: Dec 2019 --> Dec 2022
  • ||||||||||  memantine ER / Generic mfg., memantine / Generic mfg.
    Journal:  The use of Akatinol Memantine in the treatment of gait disturbances in Parkinson's disease (Pubmed Central) -  Sep 18, 2020   
    That is to say, the test formulation of memantine 10-mg tablet is bioequivalent to the reference formulation (Ebixa 10-mg tablet). The improvement in gait achieved during the study confirms that the treatment of cortical gait disturbances in patients with PD using memantine hydrochloride is a promising area of therapy.
  • ||||||||||  memantine ER / Generic mfg.
    Clinical, P2 data, Journal:  Efficacy and safety of memantine in children with autism spectrum disorder: Results from three phase 2 multicenter studies. (Pubmed Central) -  Sep 2, 2020   
    Three phase 2 trials were conducted to assess the efficacy and long-term safety of weight-based memantine extended release (ER) treatment in children with autism spectrum disorder...No new safety concerns were evident. While the a priori-defined efficacy results of the double-blind trial were not achieved, the considerable improvements in mean Social Responsiveness Scale scores from baseline in the open-label trials were presumed to be clinically important.
  • ||||||||||  memantine ER / Generic mfg., memantine / Generic mfg.
    [VIRTUAL] Experience with the drug Akatinol Memantine in the treatment of early stage dementia of the Alzheimer type. () -  Aug 2, 2020 - Abstract #AAIC2020AAIC_3371;    
    During treatment with small doses of haloperidol, we also used at a dose of memantine Akatinol 10-30mg/d, 1-2 times a day for 6 months following the BA, which was subject to fluctuations. This little experience with the drug memantine Akatinol we extend the purpose of identifying significant degree of positive impact of dementia, including Alzheimer's type.
  • ||||||||||  memantine ER / Generic mfg.
    Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Jun 11, 2020   
    P1,  N=20, Recruiting, 
    This little experience with the drug memantine Akatinol we extend the purpose of identifying significant degree of positive impact of dementia, including Alzheimer's type. Trial primary completion date: Jan 2020 --> Jul 2020
  • ||||||||||  memantine / Generic mfg.
    Clinical, Journal:  Different types of cognitive rehabilitation in patients with type 2 diabetes (Pubmed Central) -  Feb 14, 2020   
    Treatment with akatinol memantine was most effective compared to computerized training and exercise therapy. With the exception of the control group, all groups, in particular the exercise therapy group, showed the improvement in carbohydrate metabolism.
  • ||||||||||  memantine ER / Generic mfg.
    Trial completion date, Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Jan 27, 2020   
    P1,  N=20, Recruiting, 
    With the exception of the control group, all groups, in particular the exercise therapy group, showed the improvement in carbohydrate metabolism. Trial completion date: Dec 2018 --> Dec 2020 | Trial primary completion date: Nov 2018 --> Jan 2020
  • ||||||||||  masupirdine (SUVN-502) / Suven Life Sciences, Namzaric (memantine ER/donepezil) / Allergan, Adamas, donepezil / Generic mfg.
    [VIRTUAL] MASUPIRDINE (SUVN-502) IN COMBINATION WITH DONEPEZIL AND MEMANTINE - PATIENTS WITH MODERATE AD - MEMANTINE REGIMEN, CONCENTRATIONS AND TREATMENT DURATION (EXHIBITION HALL) -  Jan 6, 2020 - Abstract #AATADPD2020AAT_ADPD_790;    
    Results In the mITT population, 65.7% of subjects were on donepezil 10 mg+memantine 10 mg BID; 17.9% were on donepezil 10 mg daily+Namenda XR 28 mg daily; and 16.4% were on Namzaric – there is no significant differences in assignment across the three treatment arms. Conclusions The results of these exploratory subgroup analyses to assess potential differential effects of memantine regimen, memantine plasma concentrations and memantine treatment duration on outcome measures in this masupridine triple therapy trial will be presented.
  • ||||||||||  donepezil / generics, memantine / generics
    Journal:  Rural Disparities in Alzheimer's Disease-Related Community Pharmacy Care in the United States. (Pubmed Central) -  Nov 19, 2019   
    We found disparities in AD-related services in community pharmacies located in more rural counties, wherein individuals with AD and their caregivers may face barriers to obtaining quality pharmaceutical care. There is a need to strengthen pharmacists' knowledge and improve pharmacy services to reduce disparities.
  • ||||||||||  memantine / generics
    Journal:  Modern views on gait impairment in Parkinson`s disease and its correction (Pubmed Central) -  May 18, 2019   
    Attention is drawn to the fact that the use of memantine hydrochloride (akatinol memantine) is a promising direction for gait impairment correction in the advanced and late stages of PD due to the improvement of glutamatergic transfer from the striatum to the specific areas of the cerebral cortex involved in gait control. The results of the latest clinical trials are analyzed.
  • ||||||||||  donepezil / Generic mfg.
    Quintuple Hypotheses Targeted in Schizophrenia: Fight Fire With Fire (Regency S-V) -  Apr 3, 2019 - Abstract #SIRS2019SIRS_215;    
    The galantamine-memantine combination was significantly better for cognition than the 1 donepezil-memantine combination in patients with Alzheimer’s disease...Participants received galantamine ER 24 mg and memantine XR 21 mg for four weeks...This combination targets the quintuple hypotheses (dopamine, nicotinic-cholinergic, glutamatergic/NMDA, GABA, and KYNA) concurrently and has the potential to treat positive, cognitive, and primary negative symptoms. The galantamine-memantine combination has the potential to become the first antischizophrenia treatment.
  • ||||||||||  memantine ER / Generic mfg.
    Trial primary completion date, Combination therapy:  Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy (clinicaltrials.gov) -  Mar 20, 2019   
    P=N/A,  N=20, Recruiting, 
    The galantamine-memantine combination has the potential to become the first antischizophrenia treatment. Trial primary completion date: Dec 2018 --> Dec 2019
  • ||||||||||  memantine ER / Generic mfg.
    Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Aug 8, 2017   
    P,  N=20, Recruiting, 
    Trial primary completion date: Sep 2017 --> Sep 2018 Trial primary completion date: Nov 2017 --> Nov 2018
  • ||||||||||  memantine ER / Generic mfg.
    Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Mar 3, 2017   
    P,  N=20, Recruiting, 
    Trial primary completion date: Mar 2017 --> Jun 2017 Trial primary completion date: Nov 2016 --> Nov 2017
  • ||||||||||  memantine ER / Generic mfg., galantamine extended release / Generic mfg.
    Enrollment change, Trial termination, Trial primary completion date:  Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia (clinicaltrials.gov) -  Oct 12, 2016   
    P2,  N=3, Terminated, 
    Trial primary completion date: Nov 2016 --> Nov 2017 N=10 --> 3 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Jul 2016; Funding no longer available and PI no longer working at the institution
  • ||||||||||  memantine ER / Generic mfg.
    Trial primary completion date:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  Nov 5, 2015   
    P0,  N=20, Recruiting, 
    Phase classification: P2 --> P2a Trial primary completion date: Jan 2015 --> Nov 2016
  • ||||||||||  memantine ER / Generic mfg.
    Enrollment change, Trial initiation date, Trial withdrawal:  Cortical Metrics Assessment Outcome Measure Development in Autism With Memantine Treatment (clinicaltrials.gov) -  Oct 27, 2015   
    P=N/A,  N=0, Withdrawn, 
    Trial primary completion date: Jan 2015 --> Nov 2016 N=15 --> 0 | Initiation date: Apr 2015 --> Jul 2015 | Not yet recruiting --> Withdrawn
  • ||||||||||  memantine ER / Generic mfg., galantamine extended release / Generic mfg.
    Trial primary completion date:  Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia (clinicaltrials.gov) -  Sep 28, 2015   
    P2,  N=10, Recruiting, 
    N=15 --> 0 | Initiation date: Apr 2015 --> Jul 2015 | Not yet recruiting --> Withdrawn Trial primary completion date: Sep 2015 --> Sep 2017
  • ||||||||||  memantine ER / Generic mfg.
    Clinical:  Memantine for Enhanced Stroke Recovery (clinicaltrials.gov) -  May 20, 2014   
    P0,  N=20, Recruiting,