Leunase (L-asparaginase) / Kyowa Kirin 
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 0 Diseases   4 Trials   4 Trials   74 News 


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  • ||||||||||  Blincyto (blinatumomab) / Astellas, Amgen
    Trial completion date:  AALL1331: Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia (clinicaltrials.gov) -  Jan 25, 2023   
    P3,  N=669, Active, not recruiting, 
    Inhibition of the ISR pathway through the potent and selective small molecule modulator of GCN2, DP-9024, synergized with ASNase and re-sensitized leukemic cells to amino acid withdrawal in vitro as well as in leukemic xenograft models in vivo. Trial completion date: Dec 2030 --> Jun 2023
  • ||||||||||  Rituxan (rituximab) / Roche
    Trial completion date, Trial primary completion date:  Rituximab+mVPDL for CD20(+) Adult Acute Lymphoblastic Leukemia (clinicaltrials.gov) -  Jul 24, 2018   
    P2,  N=78, Active, not recruiting, 
    Trial primary completion date: Sep 2018 --> Dec 2018 Trial completion date: Oct 2017 --> Jan 2019 | Trial primary completion date: Oct 2017 --> Jan 2018
  • ||||||||||  Rituxan (rituximab) / Roche
    Enrollment closed, Trial primary completion date:  Rituximab+mVPDL for CD20(+) Adult Acute Lymphoblastic Leukemia (clinicaltrials.gov) -  Jul 21, 2017   
    P2,  N=78, Active, not recruiting, 
    Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2015 --> Oct 2017