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5 Diseases |  |
0 Trials |
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0 Trials |  |
17 News |  |
- REGPARA / Kyowa Kirin
Influence of the TNF?/ TNF? Receptor Axis on Human Kidney Graft Survival (Poster Hall, Exhibit Hall A, Level 2) - May 6, 2024 - Abstract #ATC2024ATC_534;
TNF-?/CD120a/CD120b/TACE balance is critical in the long-term survival of rejection-free kidney allografts.
- REGPARA / Kyowa Kirin, Amsidine (amsacrine) / Kyowa Kirin
GENETIC BIOMARKERS PREDICTING PROGNOSIS IN PATIENTS WITH CHOLANGIOCARCINOMA; A BIOINFORMATICS APPROACH STUDY (Hall A, Poster Hall - Walter E. Washington Convention Center) - Mar 14, 2024 - Abstract #DDW2024DDW_3805;
Identification of certain genes by bioinformatic approach can optimize prognostication in patients with CC. It also shed light into mechanistic pathways and suggest potential pharmacologic targets for management of CC.
- | REGPARA / Kyowa Hakko Kirin
Journal: Noise-Adaptive Non-Blind Image Deblurring. (Pubmed Central) - Sep 30, 2022
The system is shown to operate well for input noise in a three orders of magnitude range (0.01-10.0) and a wide spectrum of 1D or 2D Gaussian blur kernels, well outside the scope of most previously explored image blur and noise degrees. The proposed method is found to significantly outperform several leading state-of-the-art approaches.
- | REGPARA / Kyowa Hakko Kirin
Biomarker, Journal: MicroRNA related prognosis biomarkers from high throughput sequencing data of kidney renal clear cell carcinoma. (Pubmed Central) - Nov 29, 2021
The proposed method is found to significantly outperform several leading state-of-the-art approaches. The current study provided novel insights into the miRNA related mRNA network in KIRC and those 2 DEGs biomarkers and 3 DEMs biomarkers may be independent prognostic signatures in predicting the survival of KIRC patients.
- | cinacalcet HCl / Generic mfg.
Trial completion, Phase classification: PROCEED: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients (clinicaltrials.gov) - May 19, 2021
P4, N=67, Completed, Sponsor: The University of Hong Kong
The current study provided novel insights into the miRNA related mRNA network in KIRC and those 2 DEGs biomarkers and 3 DEMs biomarkers may be independent prognostic signatures in predicting the survival of KIRC patients. Recruiting --> Completed | Phase classification: PN/A --> P4
- | REGPARA / Kyowa Hakko Kirin
Biomarker, Journal: MicroRNA-Related Prognosis Biomarkers from High-Throughput Sequencing Data of Colorectal Cancer. (Pubmed Central) - Apr 27, 2021
In this study, we found several candidate prognostic biomarkers which have been identified in various cancers and also found several new prognosis biomarkers of COAD and READ. In conclusion, this analysis based on theoretical knowledge and clinical outcomes we have done needs further confirmation by more researches.
- |||| REGPARA / Kyowa Kirin
Trial completion, Trial primary completion date: Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT (clinicaltrials.gov) - Mar 17, 2020
P4, N=750, Completed, Sponsor: Kyowa Hakko Kirin China Pharmaceutical Co., LTD.
In conclusion, this analysis based on theoretical knowledge and clinical outcomes we have done needs further confirmation by more researches. Active, not recruiting --> Completed | Trial primary completion date: Aug 2019 --> Apr 2019
- | REGPARA / Kyowa Kirin
Enrollment closed, Trial primary completion date: Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT (clinicaltrials.gov) - Jun 17, 2019
P4, N=750, Active, not recruiting, Sponsor: Kyowa Hakko Kirin China Pharmaceutical Co., LTD.
Active, not recruiting --> Completed | Trial primary completion date: Aug 2019 --> Apr 2019 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2019 --> Aug 2019
- |||| REGPARA / Kyowa Kirin
Enrollment open: Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT (clinicaltrials.gov) - Sep 14, 2017
P4, N=750, Recruiting, Sponsor: Kyowa Hakko Kirin China Pharmaceutical Co.,LTD.
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2019 --> Aug 2019 Not yet recruiting --> Recruiting
- ||||| REGPARA / Kyowa Kirin
New P4 trial: Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT (clinicaltrials.gov) - Apr 20, 2017
P4, N=750, Not yet recruiting, Sponsor: Kyowa Hakko Kirin China Pharmaceutical Co.,LTD.
- | REGPARA / Kyowa Kirin
Trial primary completion date: The Study of Efficacy and Safety of REGPARA Drug in Dialysis Patients Have High Blood Levels of Parathyroid (clinicaltrials.gov) - Mar 28, 2017
P4, N=60, Completed, Sponsor: Chulalongkorn University
Not yet recruiting --> Recruiting Trial primary completion date: Jun 2014 --> Feb 2015
- cinacalcet HCl / Generic mfg.
Enrollment change, Trial primary completion date: PROCEED: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients (clinicaltrials.gov) - Jan 10, 2017
P=N/A, N=70, Recruiting, Sponsor: The University of Hong Kong
Trial primary completion date: Jun 2014 --> Feb 2015 N=50 --> 70 | Trial primary completion date: Dec 2016 --> Dec 2017
- cinacalcet HCl / Generic mfg.
Trial primary completion date: PROCEED: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=50, Recruiting, Sponsor: The University of Hong Kong
N=50 --> 70 | Trial primary completion date: Dec 2016 --> Dec 2017 Trial primary completion date: Dec 2014 --> Dec 2016
- | REGPARA / Kyowa Kirin
New P4 trial: The Study of Efficacy and Safety of REGPARA Drug in Dialysis Patients Have High Blood Levels of Parathyroid (clinicaltrials.gov) - Feb 4, 2014
P4, N=60, Recruiting, Sponsor: Chulalongkorn University
- cinacalcet HCl / Generic mfg.
Enrollment change: PROCEED: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients (clinicaltrials.gov) - Jun 18, 2013
P=N/A, N=50, Recruiting, Sponsor: The University of Hong Kong
Trial primary completion date: Dec 2014 --> Dec 2016 N=40 --> 50
- cinacalcet HCl / Generic mfg.
Clinical: PROCEED: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients (clinicaltrials.gov) - Oct 4, 2011
P=N/A, N=50, Recruiting, Sponsor: The University of Hong Kong