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- | Journal: Exploring the Prevalence and Resistance of Campylobacter in Urban Bird Populations. (Pubmed Central) - May 24, 2024
In contrast, resistance to streptomycin was low (5.8%), and all the isolates showed susceptibility to erythromycin and gentamycin. The results underline the importance of urban birds as reservoirs of thermophilic antimicrobial-resistant Campylobacter and contribute to enhancing the knowledge of its distribution in urban and peri-urban ecosystems.
- | nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Detection of Salmonella Pathogenicity Islands and Antimicrobial-Resistant Genes in Salmonella enterica Serovars Enteritidis and Typhimurium Isolated from Broiler Chickens. (Pubmed Central) - May 24, 2024
The findings of this study revealed that S. Typhimurium is the most prevalent serotype detected in chicken feces. To reduce the risk to human health posed by salmonellosis, a stringent public health and food safety policy is required.
- | Journal: Antimicrobial Resistance and Associated Risk Factors for Clostridium difficile in Patients Attending Tertiary Care Settings. (Pubmed Central) - May 24, 2024
The high frequency of C. difficile in Peshawar, Pakistan, indicates that CDI is an important nosocomial infection in different hospitals. The results will be helpful for clinicians to redesign control and therapeutic strategies in hospitals.
- | nalidixic acid / Generic mfg., colistin sulphate / Generic mfg.
Journal: Prevalence and antimicrobial susceptibility of Salmonella enteritidis and Salmonella typhimurium isolated from hen eggs and quail eggs in Karaj, Iran. (Pubmed Central) - May 13, 2024
are associated with human food poisoning, continuous surveillance is required to effectively reduce the risk posed by contaminated poultry eggs. Furthermore, mandatory monitoring of antimicrobial use on Iranian poultry farms is recommended.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., colistin sulphate / Generic mfg.
Journal: Epidemiological and Whole Genome Sequencing Analysis of Restaurant Salmonella Enteritidis Outbreak Associated with an Infected Food Handler in Jiangxi Province, China, 2023. (Pubmed Central) - May 10, 2024
As an overlooked contamination source, infected food handlers can easily cause large-scale outbreaks. This outbreak highlighted that the government should enhance the training and supervision of food hygiene and safety for food handlers to prevent foodborne outbreaks.
- | Retrospective data, Journal: Short reads-based characterization of pathotype diversity and drug resistance among Escherichia coli isolated from patients attending regional referral hospitals in Tanzania. (Pubmed Central) - Apr 27, 2024
This outbreak highlighted that the government should enhance the training and supervision of food hygiene and safety for food handlers to prevent foodborne outbreaks. Whole genome sequencing reveals the presence of hybrid pathotypes with increased drug resistance among E. coli isolated from regional referral hospitals in Tanzania.
- | Journal: Changing Epidemiology and Antimicrobial Resistance of Bacterial Childhood Diarrhea: Insights from a 7-Year Study in an Iranian Referral Hospital. (Pubmed Central) - Apr 24, 2024
Salmonella group D demonstrated elevated resistance to ciprofloxacin (81.3%) and nalidixic acid (88.5%), with notable sensitivity to trimethoprim-sulfamethoxazole and cefotaxime (97.3% and 97.5%, respectively)...The fluctuating prevalence of S. sonnei and Salmonella group D, two predominant bacterial isolates associated with AGE, underscores the dynamic nature of these pathogens. The notable increase in antibiotic resistance observed in S. sonnei raises concerns, underscoring the critical need for judicious and careful antibiotic use.
- | nalidixic acid / Generic mfg.
Journal: High prevalence of plasmid-mediated quinolone resistance in escherichia coli strains producing extended-spectrum beta-lactamases isolated from faeces and urine of pregnant women with acute cystitis. (Pubmed Central) - Apr 24, 2024
The strains represented virulence factors and phylogenetic group B2 are closely associated with abundance in UTI and faeces. However, the predominant clones in faeces were not found in UTIs and it is possible that rep-PCR is not sufficiently discriminating clones.
- | Journal: Prevalence of Antimicrobial Resistance Among the Hydrogen Sulfide Producing Bacteria Isolated on XLD Agar from the Poultry Fecal Samples. (Pubmed Central) - Apr 23, 2024
Also, fourteen Citrobacter strains showed resistance towards azithromycin, and furthermore, eleven of them were also resistant to streptomycin...The results on biofilm formation have also demonstrated three Salmonella strains along with nine Citrobacter strains to have the ability to form moderate biofilm. The study thus describes the occurrence of HS producing multidrug-resistant bacteria in poultry feces, which might contribute towards the dissemination of antibiotic resistance genes to other microorganisms including human pathogens with likely
- | nalidixic acid / Generic mfg.
Journal: Screening of antibiogram, virulence factors, and biofilm production of Staphylococcus aureus and the bio-control role of some probiotics as alternative antibiotics. (Pubmed Central) - Apr 22, 2024
The highest resistance of S. aureus was to Kanamycin (100%) and Nalidixic acid (89.3%), respectively...Production of staphylococcal enterotoxins, as well as biofilm production are responsible for public health risks. Therefore, installing proper hygienic routines and harsh food safety policies at food chain levels is substantial.
- | Journal: Prevalence and antibiogram of shigatoxinproducing E. coli in camel meat and offal. (Pubmed Central) - Apr 22, 2024
However, the isolates were sensitive to Meropenem and cefoxitin...Therefore, strict hygienic measures are highly recommended during the processing of camel meat. The use of coriander oil during camel meat processing is highly recommended to reduce E. coli count.
- | Journal: Transcriptional responses of cytokines, immunoglobulin A, and nitric oxide genes in 1-day-old chicks post Salmonella typhimurium infection: An experimental study. (Pubmed Central) - Apr 22, 2024
The findings indicated a strong mucosal immune response in the chicks after the ST challenge, which reflects humoral and cellular responses. Our insight recommended the occurrence of a natural immune response stimulator at 1 day age to face the infection, and this can prevent the resistance transfer, with efficient control measures.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg.
Journal: Megaplasmid Dissemination in Multidrug-Resistant Salmonella Serotypes from Backyard and Commercial Broiler Production Systems in the Southeastern United States. (Pubmed Central) - Apr 18, 2024
Plasmids that have been associated with MDR were found in Kentucky and Infantis isolates, particularly IncFIB(K)_1_Kpn3 megaplasmid (Infantis). Our study emphasizes the need to understand the selection pressures in disseminating megaplasmids in MDR Salmonella in distinct broiler production systems.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Virulence Genes, Antimicrobial Resistance, and Genotypes of Campylobacter jejuni Isolated from Chicken Slaughterhouses in South Korea. (Pubmed Central) - Apr 12, 2024
The MLST-based genetic relatedness between isolates from humans and chicken slaughterhouses in this study suggests the potential of C. jejuni transmission from chickens to humans through the food chain. This study suggests the need for improved management practices in chicken slaughterhouses to reduce the transmission of chicken slaughterhouse-derived C. jejuni to humans.
- | Journal: Antimicrobial Resistance Patterns in Patients with Vaginal Discharge: A 2019-2022 Analysis at the National Health Laboratory in Eritrea. (Pubmed Central) - Apr 9, 2024
exhibited high resistance (>43%) to antibiotics such as cephalexin, ceftazidime, nalidixic acid, ampicillin, gentamicin, and tetracycline...Gram-positive bacteria have resistance rates of more than 49% with ampicillin, trimethoprim-sulfamethoxazole, tetracycline, oxacillin, vancomycin, and penicillin G. In particular, S. aureus demonstrated no resistance to rifampicin or clindamycin, while Streptococcus spp...This study highlights critical gaps and areas for further exploration. Expanding the spectrum of antibiotics tested and investigating underlying multidrug resistance mechanisms would provide a more comprehensive understanding of resistance patterns.
- | nalidixic acid / Generic mfg.
Journal: Antioxidant and antibacterial activities of 5-mercapto(substitutedthio)-4-substituted-1,2,4-triazol based on nalidixic acid: A comprehensive study on its synthesis, characterization, and In silico evaluation. (Pubmed Central) - Apr 4, 2024
Furthermore, compounds 3b, 4i, and 4m, identified through drug-likeness and toxicity predictions, were highlighted for their favorable profiles, suggesting their suitability for oral antibiotic therapies. This comprehensive study, blending synthetic, in vitro, and in silico approaches, emphasizes the triazole derivatives' potential as future candidates for antibiotic and antioxidant applications, particularly spotlighting compounds 3b, 4i, and 4m due to their promising efficacy and safety profiles.
- | Journal: Prevalence and antimicrobial resistance of Enterobacteriaceae in the north of Kazakhstan. (Pubmed Central) - Apr 2, 2024
The most common genes encoding antimicrobial resistance were as follows: BlaTEM and OXA in 41 and 28 isolates, respectively, encoding resistance to beta-lactams; StrA and StrB in 45 and 48 isolates encoding aminoglycosides; and tetA and tetB in 43 and 28 isolates encoding tetracyclines. Obtained data demonstrate that uncontrolled and frequent use of beta-lactam and tetracycline antibacterials, in cats and dogs, results in the spread of genotypic resistance among micro-organisms of the family Enterobacteriaceae.
- | Journal: Genetic Characteristics of Extended-Spectrum Beta-Lactamase-Producing Salmonella Isolated from Retail Meats in South Korea. (Pubmed Central) - Apr 2, 2024
The major plasmid replicons of the Enteritidis-ST11 strains were IncFIB(S) and IncFII(S), carrying antimicrobial resistance genes (?-lactam, tetracycline, and aminoglycoside) and 166 virulence factor genes. The results of this study provide valuable insights for the surveillance and monitoring of ESBL-Sal in South Korean food chain.
- | nalidixic acid / Generic mfg.
Journal: The spontaneously produced lysogenic prophage phi456 promotes bacterial resistance to adverse environments and enhances the colonization ability of avian pathogenic Escherichia coli strain DE456. (Pubmed Central) - Mar 31, 2024
Additionally, phage particles were no longer observed either during normal growth or induced by nalidixic acid in DE456?phi456...The qRT-PCR results indicated that the expression levels of the subunit of I fimbriae (fimA) and its apical adhesin (fimH) were significantly lower in DE456?phi456. Therefore, it can be concluded that phi456 plays a crucial role in helping bacterial hosts survive in unfavorable conditions and enhancing the colonization ability in DE456.
- | nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Evaluation of in-feed supplementation of formic acid and thymol as non-antibiotic growth promoters and assessing their effect on antimicrobial resistant E.coli isolated in Turkey. (Pubmed Central) - Mar 28, 2024
blaAmpC gene was significantly (p?<?0.001) harbored in T2 isolates whereas least detected in T5 and T8. It was inferred that formic acid (7.5
- | Journal: Evaluation of the probiotic potential of yeast isolated from kombucha in New Zealand. (Pubmed Central) - Mar 25, 2024
Notably, two of the fifteen strains (Pichia kudraivzevii GBY1 and Saccharomyces cerevisiae GBY2) exhibited desirable cell surface hydrophobicity (64.60-83.87%), auto-aggregation (>98%), co-aggregation, resistance to eight tested antibiotics (ampicillin, chloramphenicol, colistin sulphate, kanamycin, nalidixic acid, nitrofurantoin, streptomycin, and tetracycline), and high levels of antioxidant activities (>90%). Together, our data reveal the probiotic activities of two yeast strains GBY1 and GBY2 and their potential application in functional food production.
- | nalidixic acid / Generic mfg., meropenem / Generic mfg., colistin sulphate / Generic mfg.
Journal: Phenotypic and genotypic characterization of Escherichia coli isolated from the chicken liver in relation to slaughterhouse conditions. (Pubmed Central) - Mar 22, 2024
Based on the MIC test findings, colistin resistance was 46.9% (107/228)...In conclusion, these findings highlight the importance of implementing biosecurity measures in slaughterhouses to reduce antibiotic-resistant E. coli spread. Furthermore, this study provides valuable insights into the effects of wet market (Natafat) slaughter conditions on increasing bacterial resistance and virulence.
- | nalidixic acid / Generic mfg., tetracycline / Generic mfg., erythromycin / Generic mfg.
Journal: Macrolide resistance in Mannheimia haemolytica isolates associated with bovine respiratory disease from the German national resistance monitoring program GERM-Vet 2009 to 2020. (Pubmed Central) - Mar 18, 2024
Antimicrobial susceptibility testing (AST) was performed via broth microdilution according to the recommendations of the Clinical and Laboratory Standards Institute for the macrolides erythromycin, tilmicosin, tulathromycin, gamithromycin, tildipirosin, and tylosin as well as 25 other antimicrobial agents...In addition, mutational changes conferring resistance to macrolides, nalidixic acid or streptomycin, respectively, were detected among the M. haemolytica isolates...The detection of the macrolide resistance genes erm(T), mef (C), and mph(G) together with other resistance genes on MDR-mediating ICEs in bovine M. haemolytica may explain the occurrence of therapeutic failure when treating BRD with regularly used antimicrobial agents, such as phenicols, penicillins, tetracyclines, or macrolides. Finally, pathogen identification and subsequent AST is essential to ensure the efficacy of the antimicrobial agents applied to control BRD in cattle.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Journal: Smelly shark, smelly ray: what is infecting you? (Pubmed Central) - Mar 15, 2024
Finally, pathogen identification and subsequent AST is essential to ensure the efficacy of the antimicrobial agents applied to control BRD in cattle. The detection of several pathogenic and antibiotic-resistant bacteria may pose significant Public Health risks in Brazil, due to high elasmobranch consumption rates, indicating the urgent need for further bacteriological assessments in this group.
- | ciprofloxacin oral / Generic mfg.
Journal: Antibiotic susceptibility and genomic analysis of ciprofloxacin-resistant and ESBLs-producing Escherichia coli in vegetables and their irrigation water and growing soil. (Pubmed Central) - Mar 11, 2024
In conclusion, our research highlights the widespread presence of CIPRE. coli in irrigation water and thoroughly examines the genetic characteristics of CIPR-ESBLs-producing E. coli strains, underlining the need for ongoing monitoring and management to reduce multidrug-resistant bacteria in vegetables and their environment.
- | Preclinical, Journal: Unveiling distinct genetic features in multidrug-resistant Escherichia coli isolated from mammary tissue and gut of mastitis induced mice. (Pubmed Central) - Mar 4, 2024
Furthermore, there were 43 and 111 unique genes identified in G2M6U and G6M1F genomes, respectively. These results indicate distinct differences in the genomic characteristics of E. coli strain G2M6U and G6M1F that might have important implications in the pathophysiology of mammalian mastitis, and treatment strategies for mastitis in dairy animals.
- | Cubicin (daptomycin) / Merck (MSD)
Journal: Impact of zinc supplementation on phenotypic antimicrobial resistance of fecal commensal bacteria from pre-weaned dairy calves. (Pubmed Central) - Feb 28, 2024
However, a significant reduction in E. coli MIC values was observed for ciprofloxacin (MR?=?0.17, 95% CI 0.03-0.97) and nalidixic acid (MR?=?0.28, 95% CI 0.15-0.53) for zinc-treated compared to placebo-treated calves. Alongside predictions of MIC values generated from these 17 AFT models, findings from this study corroborate the influence of age and antimicrobial exposure on phenotypic AMR.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., amoxycillin/clavulanate / Generic mfg.
Journal: Typhoidal salmonella disease in Mukuru informal settlement, Nairobi Kenya; carriage, diversity, and antimicrobial resistant genes. (Pubmed Central) - Feb 27, 2024
The sharp increase in nalidixic acid resistance is an indication of reduced susceptibility to fluoroquinolones, which are currently the recommended drugs for the treatment of typhoid fever. This study highlights the need for effective antimicrobial stewardship and routine surveillance of antimicrobial resistance (AMR) to inform policy on the prevention and control of MDR Typhoid disease.
- | Journal: The Antimicrobial Resistance of Enterotoxigenic Escherichia coli from Diarrheal Patients and the Environment in Two Geographically Distinct Rural Areas in Bangladesh over the Years. (Pubmed Central) - Feb 24, 2024
Notably, 80-100% of the ETEC strains were susceptible to tetracycline and quinolones (ciprofloxacin and norfloxacin), both in clinical and aquatic ETEC...The patterns of excessive or limited consumption of drugs to treat diarrhea over time in Bangladesh were reflected in the ETEC AMR from the patients and the environment. The high prevalence of MDR-ETEC strains in humans and the environment is of concern, which calls for vaccines and other preventative measures against ETEC.
- | Journal: Comparison of the Antibiotic Resistance of Escherichia coli Populations from Water and Biofilm in River Environments. (Pubmed Central) - Feb 23, 2024
The different factors in water and the sediment do not appear to influence the stability of resistance. The minimal differences observed upstream and downstream of the cities could indicate that the river population already exhibits generalized resistance.
- | nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Prevalence and changing antimicrobial resistance profiles of Shigella spp. isolated from diarrheal patients in Kolkata during 2011-2019. (Pubmed Central) - Feb 20, 2024
The elucidation of this study's outcome is helpful not only in identifying emerging antimicrobial resistance patterns of Shigella spp. but also in developing treatment guidelines appropriate for this region.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: High levels of multidrug-resistant isolates of genetically similar Salmonella 1,4, [5],12:I:- from Brazil between 1983 and 2020. (Pubmed Central) - Feb 20, 2024
Furthermore, the ERIC-PCR and MLST results suggested that most strains belonged to one main cluster. Thus, a prevalent subtype of Salmonella 1,4, [5],12:i:- strains has probably been circulating among different sources in S
- | Journal: Prevalence and molecular characteristics of Shewanella infection in diarrhea patients in Beijing, China 2017-2019. (Pubmed Central) - Feb 15, 2024
Monitoring for Shewanella spp. should be added to the routine surveillance of infectious diarrhea during the epidemic season.
- | Journal: Molecular characterization of Campylobacter spp. isolates obtained from commercial broilers and native chickens in Southern Thailand using whole genome sequencing. (Pubmed Central) - Feb 10, 2024
This study contributes to a deeper understanding of the molecular epidemiology of Campylobacter spp. in Thai chicken production systems.
- | Journal: Prevalence, antibiotic resistance, and genomic characterisation of Campylobacter spp. in retail chicken in Hanoi, Vietnam. (Pubmed Central) - Jan 31, 2024
The 32 isolates belonged to clonal complexes associated with both poultry and people, such as CC828 for C. coli. These results contribute to the One Health approach for addressing Campylobacter in Vietnam by providing detailed new insights into a main source of human infection and can inform the design of future surveillance approaches.
- || Review, Journal: A Review on the Antibiotic Resistance of Shigella Strains in Iran. (Pubmed Central) - Jan 30, 2024
People should be informed about the threat of antimicrobial-resistant bacteria, so a periodic report of antibiotic susceptibility after analysis is essential for antibiotic treatment guidance. The present study provides a brief overview of the pathogenicity of Shigella spp., and the antibiotic resistance patterns of two common Shigella species during the last seven years in Iran were evaluated.
- | Journal: Prevalence of plasmid-mediated quinolone resistance and 16S rRNA methylase genes among Escherichia coli clinical isolates in a hospital in Saudi Arabia. (Pubmed Central) - Jan 28, 2024
A single isolate was carried three genes (qnrS, aac(6')-Ib and rmtB). As antibiotic resistance continues to become more prevalent, there is a need for extensive research to identify the genetic determinants of resistance and to develop new antibiotic therapies.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Comparison of Antimicrobial Resistance in Escherichia coli Strains Isolated From Swine, Poultry, and Farm Workers in the Respective Livestock Farming Units in Greece. (Pubmed Central) - Jan 25, 2024
Most E. coli isolates displayed significant resistance to tetracycline and ampicillin...In contrast, high resistance rates to nalidixic acid were observed in E. coli strains isolated from poultry and poultry farmers, with percentages of 66.7% and 50%, respectively...These findings highlight the potential role of antibiotic use in animals as a contributing factor to the development of antibiotic resistance in both animals and humans. Additionally, it suggests that individuals working on farms may be at an increased risk of acquiring antibiotic-resistant strains of E. coli due to their proximity to and interaction with animals.
- | Journal: Antimicrobial Susceptibility Patterns and Genetic Diversity of Campylobacter spp. Isolates from Patients with Diarrhea in South Korea. (Pubmed Central) - Jan 23, 2024
This study investigated the antimicrobial resistance (AMR) profiles to tetracycline (32.3%), nalidixic acid (64.9%), and ciprofloxacin (83.3%), confirming high levels of the latter even after its Korean ban in 2010...Alternatively, significantly lower resistance rates to clindamycin (0.8%), azithromycin (0.53%), erythromycin (0.53%), and gentamicin (0.53%) as well as absolute susceptibility to florfenicol (0%) were observed...The high CC21 and CC828 strain prevalence in this study was consistent with their worldwide distribution. This study highlights that quinolone- and tetracycline-resistant Campylobacter circulate in Korea with diverse genotypes, providing important information that could contribute to controlling and preventing increasing antimicrobial resistance in patients.
- | nalidixic acid / Generic mfg.
Journal: Prevalence of Salmonella in Eggs from Conventional and Cage-Free Egg Production Systems and the Role of Consumers in Reducing Household Contamination. (Pubmed Central) - Jan 17, 2024
Isolates showed resistance to nalidixic acid (100%, 2/2), and the aac(6')-Iaa gene and a mutation in the gyrA gene were identified in both isolates. Overall, consumers demonstrated knowledge regarding food safety; however, many still engage in practices that pose a risk of acquiring foodborne illnesses.
- | Journal: Water quality and phenotypic antimicrobial resistance in isolated of E. coli from water for human consumption in Bagua, under One Health approach. (Pubmed Central) - Jan 16, 2024
The presence of fecal contamination poses a significant microbiological risk to consumers. These results underscore the breakdown of the human-environment-animal interface within the One Health approach, thereby endangering public health.
- | nalidixic acid / Generic mfg., rifampicin / Generic mfg.
Journal: Novel Hydroxamic Acids Containing Aryl-Substituted 1,2,4- or 1,3,4-Oxadiazole Backbones and an Investigation of Their Antibiotic Potentiation Activity. (Pubmed Central) - Jan 15, 2024
Some of the hydroxamic acids we obtained (9c, 9d, 23a, 23c, 30b, 36) showed significant potentiation in nalidixic acid, rifampicin, and kanamycin against the growth of laboratory-strain Escherichia coli MG1655. Two lead compounds (9c, 9d) significantly reduced Pseudomonas aeruginosa ATCC 27853 growth in the presence of nalidixic acid and rifampicin.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg.
Journal: Occurrence, Antimicrobial Resistance, and Virulence Profiles of Salmonella Serovars Isolated from Wild Reptiles in South Africa. (Pubmed Central) - Jan 15, 2024
The findings highlight the necessity of educational initiatives aimed at reducing reptile-related infections. Effective antibiotic treatment appears promising for infection, given the minimal drug resistance observed in reptile Salmonella serovars in the current study.
- | Journal: Burden of enteric fever and antibiotic sensitivity in Nepalese Children Prior to Typhoid Vaccine in National Immunization Program. (Pubmed Central) - Jan 14, 2024
Salmonella species culture isolatation are declining every year. Fluoroquinolones have more resistance than first line drugs of typhoid, azithromycin resistance is rising but 3rd generation cephalosporins are sensitive to Salmonella species.
- | Journal: Antimicrobial resistance and genomic characterization of Campylobacter isolates recovered from retailed poultry meat samples in 20 provinces of China in 2020 (Pubmed Central) - Jan 12, 2024
The phenomenon of antimicrobial resistance in Campylobacter from poultry meat sources in China is relatively serious, and resistance and virulence genes are widely distributed in Campylobacter. There is genetic diversity in Campylobacter.
- | nalidixic acid / Generic mfg.
Journal: Evaluation of the Novel mTA10 Selective Broth, MSB, for the Co-Enrichment and Detection of Salmonella spp., Escherichia coli O157 and Listeria monocytogenes in Ready-to-Eat Salad Samples. (Pubmed Central) - Jan 11, 2024
Four selective agents were added, namely nalidixic acid, sodium cholate, lithium chloride and potassium tellurite, to control the growth of interfering microorganisms...Furthermore, all heavily contaminated ready-to-eat salad samples reached concentrations higher than 5 log CFU/g. Finally, after 24 h of enrichment of spiked salad, it was possible to detect concentrations below 10 CFU/25 g.
- | nalidixic acid / Generic mfg.
Journal: Supplementation of dietary areca nut extract modulates the growth performance, cecal microbiota composition, and immune function in Wenchang chickens. (Pubmed Central) - Jan 9, 2024
Proteomic analysis revealed that the differentially expressed proteins (such as interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), MHC-BF1, and death domain-associated protein (Daxx)) in the bone marrow of the chickens were primarily enriched in the immune network for IgA production and B cell receptor signaling pathway. In conclusion, dietary ANE supplementation was found to enhance metabolic activity and energy utilization, improve growth performance, modulate cecal microbiota, and strengthen the immunity of Wenchang chickens.
- | Journal: Adaptive evolution of Salmonella Typhimurium LT2 exposed to carvacrol lacks a uniform pattern. (Pubmed Central) - Jan 8, 2024
Furthermore, the demonstration of cross-resistance against heat and antibiotics exhibited by resistant variants raises concerns regarding food safety. KEY POINTS:
- | tetracycline / Generic mfg.
Journal: Impact of In-Feed versus In-Water Chlortetracycline and Tiamulin Administrations on Fecal Prevalence and Antimicrobial Susceptibilities of Campylobacter in a Population of Nursery Pigs. (Pubmed Central) - Dec 23, 2023
Campylobacter isolates were resistant to tetracycline (98.5%), ciprofloxacin (89.3%), and nalidixic acid (60.3%). Neither the antibiotic nor the route of administration had an effect (p > 0.05) on the prevalence of AMR Campylobacter in the feces of piglets.
- | nalidixic acid / Generic mfg.
Journal: Genomic analysis of Shigella isolates from Lebanon reveals marked genetic diversity and antimicrobial resistance. (Pubmed Central) - Dec 19, 2023
Notably, 27.8?% (15/54) of the isolates were resistant to third-generation cephalosporins (3GCs) and 77.8?% (42/54) were resistant to nalidixic acid...Quinolone resistance was conferred by single point mutations in the gyrA DNA gyrase gene, leading to GyrA S83L, GyrA D87Y or GyrA S83A amino acid substitutions. This is the first study, to our knowledge, to provide genomic insights into the serotypes of Shigella circulating in Lebanon and the various antimicrobial resistance determinants carried by these strains.