| Kinedak (epalrestat) / Ono Pharma |
NCT05184049: Effects of Epalrestat on Peripheral Neuropathy and Central Nervous System in Diabetic Patients |
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| Recruiting | 4 | 72 | RoW | Epalrestat,Mecobalamin, Mecobalamin | Xiangya Hospital of Central South University | Diabetes | 10/23 | 10/23 | | |
NCT04925960: Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG |
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| Active, not recruiting | 3 | 40 | US | Epalrestat, Placebo | Maggie's Pearl, LLC | Pmm2-CDG, Phosphomannomutase 2 Deficiency, Phosphomannomutase 2 Congenital Disorder of Glycosylation, Phosphomannomutase II Congenital Disorder of Glycosylation, Phosphomannomutase II Deficiency | 02/25 | 12/25 | | |
| Recruiting | 2/3 | 120 | RoW | Nebivolol+ Standard care arm, Epalrestat + Alpha Lipoic Acid +Standard care, Standard care alone | St. John's Research Institute | Diabetic Neuropathy Peripheral | 12/25 | 03/26 | | |
| Not yet recruiting | 2 | 30 | NA | Epalrestat, Epalrestat Tablets（YANGTZE River Pharmaceutical Group Nanjing Pharmaceutical. Co., Ltd.） | The Third Xiangya Hospital of Central South University | Charcot-Marie-Tooth Disease (CMT) | 04/26 | 04/26 | | |
ChiCTR2100054477: Clinical and Mechanism Study of Wa Medicine Yiqi Tongluo Recipe Regulating HIF-1/VEGF & EPO Pathway and Relieving Tissue Hypoxia for DPN |
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| Recruiting | N/A | 80 | | Epalrestat Tablets ;Yiqitongluo Decoction | Yunnan Provincial Hospital of Traditional Chinese Medicine; Yunnan Provincial Hospital of Traditional Chinese Medicine, Major Biomedicine Project of Yunnan Provincial Department of Science and Technology: Excavation, sorting and development of medical preparations for the medical experience of the Wa ethnic group | Diabetic peripheral neuropathy (DPN) | | | | |
