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| Not yet recruiting | 4 | 20 | Europe | cetirizine 10mg and Fluticasone Furoate | Maastricht University Medical Center | Seasonal Allergic Rhinitis | 05/11 | 06/11 | | |
2010-023861-23: The effect of P-glycoprotein transport inhibition on brainmechanisms of sedation and cognitive impairment following antihistamines in healthy volunteers |
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| Ongoing | 4 | 16 | Europe | Cetirizine 2HCI Sandoz, Verapamil HCI Sandoz, Cetirizine 2HCI Sandoz, verapamil HCI Sandoz, Cetirizine 2HCI Sandoz, verapamil HCI Sandoz | Maastricht University | To assess the effects of inhibition of the P-glycoproteine transporter (by verapamil 120 mg) on cetirizine 15 mg in healthy volunteers. | | | | |
NCT06288334: Exploration of the Optimal Dosage of Cetirizine in the Treatment of Allergic Diseases in Chinese Children |
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| Recruiting | 4 | 80 | RoW | 1-3 Cetirizine Pharmacokinetic samples | Peking University Third Hospital | Allergic Disease, Children | 03/24 | 05/24 | | |
NCT05095311: The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers |
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| Terminated | 4 | 16 | US | Cetirizine HCl, Zyrtec, Placebo | Indiana University | Exercise-induced Arterial Hypoxemia | 04/22 | 04/22 | | |
ChiCTR2300071435: A randomized, double-blind, positive parallel controlled trial of the efficacy and safety of Vitex mixture in the treatment of urticaria |
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| Recruiting | 4 | 72 | | JingFang Mixture+Cetirizine hydrochloride tablet simulant ;JingFang Mixture simulant+Cetirizine hydrochloride tablet | Beijing Hospital of Traditional Chinese Medicine, Capital Medical University; Lunan Houpu Pharmaceutical Co., Ltd, Jingfang Mixture manufacture | Urticaria | | | | |
ChiCTR2400081563: Epidemiological investigation of allergic diseases and real world study on prevention and treatment of allergic rhinitis in Hohhot, Inner Mongolia |
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| Completed | 4 | 400 | | The spleen aminopeptide oral solution was administered from 4 weeks to 6 weeks (±7d) before the pollen sowing period, and the treatment course was 12 weeks in total. Combination of conventional medications (cetirizine tablets and budesonide nasal spray as needed).; The spleen aminopeptide oral solution simulator was administered from 4 weeks to 6 weeks (±7d) before the pollen sowing period, and the treatment course was 12 weeks in total. Combination of conventional medications (cetirizine tablets and budesonide nasal spray as needed). | Beijing Shijitan Hospital, Capital Medical University; Beijing Ronghe Medical Development Foundation, Beijing Ronghe Medical Development Foundation | seasonal allergic rhinitis | | | | |
ChiCTR2400084502: Prophylactic intervention of spleen ammonia peptide oral solution in patients with allergic rhinitis in Hohhot, Inner Mongolia |
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| Completed | 4 | 300 | | The spleen aminopeptide oral solution was administered from 4 weeks to 6 weeks (±7d) before the pollen sowing period, and the treatment course was 12 weeks in total. Combination of conventional medications (cetirizine tablets and budesonide nasal spray as needed). | Beijing Shijitan Hospital, Capital Medical University; Beijing No.1 Biochemical Pharmaceutical Co., Ltd., Beijing No.1 Biochemical Pharmaceutical Co., Ltd. | allergic rhinitis | | | | |
ChiCTR-TRC-11001485: A comparative study on the efficacy and safety of Olopatadine Hydrochloride versus Cetirizine in the treatment of cutaneous pruritus |
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| Completed | 3 | 174 | | Olopatadine 5mg, oral taken twice daily for 2 week ;Cetirizine 10mg, oral taken once daily for 2 weeks | Peking Union Medical College Hospital; Kyowa Hakko Kogyo Co., Ltd., Kyowa Hakko Kogyo Co., Ltd.(merged with Kirin Kunpeng (China) Bio-Pharmaceutical Co.,Ltd. in Jan. 2011.) | Cutaneous pruritus | | | | |
NCT06754410: Efficacy of Antihistamine Drugs as Medical Expulsive Therapy Alone or in Combination With Alpha Blockers: A Prospective Randomized Controlled Study |
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| Completed | 3 | 480 | RoW | Tamsulosin, Cetirizine, Cetirizine + Tamsulosin, Placebo | South Valley University | Lower Ureteric Stones | 03/24 | 03/24 | | |
PRECEPT, NCT04175834: Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to Ocrelizumab |
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| Completed | 3 | 19 | US | cetrizine, Active comparator, diphenhydramine, Other | Providence Health & Services, Genentech, Inc. | Multiple Sclerosis, Infusion Reaction | 05/22 | 05/22 | | |
NCT05946551: Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial |
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| Terminated | 3 | 5 | US | Cetirizine, Famotidine, HRA, Cetirizine Placebo, Famotidine Placebo | Emory University, CURE Drug Repurposing Collaboratory (CDRC) | COVID-19 | 06/24 | 06/24 | | |
ChiCTR-IIR-17013331: Clinical Efficacy and Safety of Oral Supplement of Allium ascalonicum L. in Patients with Allergic Rhinitis |
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| Recruiting | 2 | 120 | | Cetirizine 10 mg 1 tablet hs+supplement of Allium ascalonicum L. (500 mg) 3 capsules bid ;Cetirizine 10 mg 1 tablet hs+placebo 3 capsules bid | Faculty of Medicine, Chiang Mai University; Pharmacology, Chiang Mai University | Allergic Rhinitis | | | | |
| Terminated | 1/2 | 9 | Europe, US | UX053, Placebo, Antipyretic, paracetamol, acetaminophen, ibuprofen, H2 Blocker, famotidine, H1 Blocker, cetirizine | Ultragenyx Pharmaceutical Inc, Ultragenyx Pharmaceutical Inc. | Glycogen Storage Disease Type III | 03/23 | 03/23 | | |
NCT05476679: Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse Events |
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| Completed | 1/2 | 48 | US | RZL-012, RZL-012+Lidacaine injection prior treatment, RZL-012+Medrol, RZL-012+Celecoxib+Zyrtec, RZL-012+facial and neck wrap | Raziel Therapeutics Ltd. | Submental Fat | 06/23 | 06/23 | | |
NCT06126991: Organ Protective Effect of Cetirizine In Patients With Severe Burns |
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| Recruiting | 1/2 | 32 | RoW | Cetirizine, Midazolam and Fentanyl | Ruijin Hospital | Burns | 12/24 | 12/25 | | |
| Completed | 1 | 300 | | Step 1: cetirizine 10mg qn for 1 week and diprophyllin 200mg tid until cough ceased. Step 2: prednisone 25mg qd for 1 week if failed to stop cough or budesonide inhalation 200μg bid until cough ceased. Step 3: Omeprazole 20mg bid and Domperidone 10mg tid until cough ceased or 8 weeks. ;Step 1: diprophyllin 200mg tid and compound methoxyphenamine 2 capsules tid. Other steps are the same ;- | Tongji Hospital Affiliated to Tongji University; Shanghai Committee of Science and Technology, Shanghai Committee of Science and Technology | Chronic cough | | | | |
NCT04071821: Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg |
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| Not yet recruiting | 1 | 30 | NA | cetirizine HCl Gummy, Ceteric Allergy Gummy, Zyrtec tablet 10mg | Seattle Gummy Company, Frontage Clinical Services, Inc., Frontage Laboratories, Inc. | Allergy | 07/25 | 09/25 | | |
ChiCTR2200064702: Clinical efficacy of Huang lichun auricular medicine in the treatment of allergic rhinitis |
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| Not yet recruiting | 1 | 72 | | auricular medicine therapy ;take Cetirizine hydrochloride | Tangdu Hospital, China Air Force Medical University; Tangdu Hospital, Air Force Medical University | allergic rhinitis | | | | |
ChiCTR2200062632: Clinical Study on Treatment of Allergic Conjunctivitis with Chuanjiao Fang 1 |
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| Not yet recruiting | 1 | 138 | | Chuan Jiaofang 1 Placebo + Cetirizine Tablets + Sodium Hyaluronate Eye Drops ;Chuanjiao Fang 1 + Cetirizine Tablets Placebo + Sodium Hyaluronate Eye Drops | Eye Hospital of China Academy of Chinese Medical Sciences; China Academy of Chinese Medical Sciences, Science and Technology Innovation Project of China Academy of Chinese Medical Sciences | Allergic Conjunctivitis | | | | |
ChiCTR2300068899: Effects Of “Huang’s Fuzheng Quxie“ Acupuncture on IL-23/IL-17 inflammatory axis in chronic spontaneous urticaria |
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| Not yet recruiting | 1 | 70 | | Huang's FuzhengQuxie acupuncture was used ;Cetirizine hydrochloride tablets taken orally | Shanghai Research Institute of Acupuncture and Meridian; Shanghai Research Institute of Acupuncture and Meridian, Shanghai Municipal Health Commission | chronic urticaria | | | | |
| Completed | N/A | 390 | | Cetirizine Single dose, given one hour preoperatively, versus Dexamethasone and placebo | Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong; Level of the institution：, Departmental | Postoperative nausea and vomiting | | | | |
ChiCTR-TRC-11001245: Research for 'Mind regulating acupuncture method' protocol in the treatment of allergic rhinitis |
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| Completed | N/A | 240 | | Cetirizine 10mg P.O. once daily, for 4 consecutive weeks ;Acupuncture: points selection: Yingxiang(LI20), Yintang, Baihui (GV20),Hegu(LI4), Feishu(BL13), Pishu(BL20),Shenshu(BL23),Ganshu(BL18), Dazhui(GV14),Taichong(LR3).Yingxiang(LI20),Yintang and Baihui(GV20) connects with electrostimulator after qi arrival. 20mintues for each treatment, 3 times a week for 4 consecutive weeks. | Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine; Level of the institution：, Beijing Municipal Science & Technology Commission | allergic rhinitis | | | | |
ChiCTR-OOC-17010649: Clinical and pharmacological experimental Observation on Prescription of cetirizine hydrochloride Lotion for Skin Itch Patients |
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| Not yet recruiting | N/A | 144 | | onitment | Shanghai Dermatology Hospital; Shanghai Dermatology Hospital Address, Aplying funding | Itchy skin | | | | |
ChiCTR2000035970: A Randomized Controlled Clinical Study on Chushi Zhiyang Mixture in Treating Atopic Dermatitis |
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| Not yet recruiting | N/A | 200 | | Chushi Zhiyang Mixture + Hydrocortisone butyrate cream ;Cetirizine+Hydrocortisone butyrate cream | Longhua Hospital Shanghai University of Traditional Chinese Medicine; Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai Hospital Development Center | atopic dermatitis | | | | |
H1-Switch, NCT06039137: The Effect of Switching the H1-antagonist Clemastine to Cetirizine in Premedication Regimens During Paclitaxel Treatment |
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| Completed | N/A | 395 | Europe | Cetirizine, Clemastine IV | Erasmus Medical Center | Solid Tumor | 04/23 | 10/23 | | |
| Not yet recruiting | N/A | 144 | | Compound Yinhualishi granules+Cetirizine+Single cream ;Placebo + Cetirizine + Single cream | Shanghai Skin Disease Hospital; Shanghai Skin Disease Hospital, Self-funded by the researcher | eczema | | | | |
ChiCTR2200063420: Clinical observation of the Wei Rou nourishing and moisturizing essence cream in adjuvant treatment of adults with atopic dermatitis |
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| Not yet recruiting | N/A | 60 | | Weirou nourishing and moisturizing essence cream, for external use, twice a day, once in the morning and once in the evening, evenly coated throughout the body, with a weekly dosage of 250 g. Basic treatment: cetirizine hydrochloride tablets: 1 to 7 days, orally, 10 mg/time, once a day at night. Des ;blank matrix, for external use, twice a day, once in the morning and once in the evening, evenly coated throughout the body, with a weekly dosage of 250 g. Basic treatment: cetirizine hydrochloride tablets: 1 to 7 days, orally, 10 mg/time, once a day at night, desonide cream: 1 to 21 days, t | Huashan Hospital of Fudan University; Guang Cr.shunfeng Pharmaceutical Co., Ltd, Guang Cr.shunfeng Pharmaceutical Co., Ltd | Atopic dermatitis | | | | |
NCT06535087: The Impact of Airway Allergic Diseases on Children's and Parents' Quality of Life |
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| Recruiting | N/A | 600 | RoW | Subcutaneous immunotherapy / Standard Treatment for Asthma and Rhinitis, Alutard, Antergen, Xolair, Pulmicort, Bricanyl, Singulair, Zyrtec | Wenjing Zhou | Pediatric Asthma, Rhinitis, Allergic, Quality of Life | 06/25 | 05/27 | | |
ChiCTR2300068685: A single-center, randomized, double-blind controlled clinical study of Wubailishi Granules in the treatment of mild to moderate eczema |
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| Not yet recruiting | N/A | 144 | | Wubailiazi granules + cetirizine + Disongzhangbo cream ;Placebo + cetirizine + Disongzhangbo cream | Shanghai Skin disease Hospital; Shanghai Skin disease Hospital, Self-funded by the researcher | Eczema | | | | |
ChiCTR2400090953: A prospective randomized controlled clinical trial of probiotics in the treatment of patients with allergic rhinitis |
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| Recruiting | N/A | 360 | | Probiotics were started before the pollen dispersal period for a total of 12 weeks. If symptoms occur during pollen dispersal, use conventional medications (cetirizine tablets and budesonide nasal spray as needed) in addition to probiotic therapy.; Placebo was started before the pollen dispersal phase for a total of 12 weeks and continued throughout the pollen dispersal phase. If the patient develops symptoms during pollen dispersal, conventional treatment may be used) Cetirizine tablets and Budesonide nasal spray may be taken as needed). | Hohhot First Hospital; The First Hospital of Hohhot, 2024 Health Science and Technology Plan Project of Hohhot (No.2024-Huweike-002) | Allergic rhinitis | | | | |
ChiCTR2400083496: Clinical efficacy and safety observation of Xinyi San modified granules in the treatment of allergic rhinitis with deficient cold of lung Qi syndrome |
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| Not yet recruiting | N/A | 99 | | Xinyi San modified granules++Basic western medicine treatment; Xinyi San modified decoction+Basic western medicine treatment; For basic treatment of western medicine, Fluticasone Propionate Nasal Spray (produced by Fushuna, GlaxoSmith K line S. A, specification 50ug/120 spray, once a day, nasal spray 2 times per side in the morning, national drug approval number HJ20140117), cetirizine hydrochloride tablets (produced by Chengdu Lier Pharmaceutical Co., Ltd., specification 10mg, administration method: 10mg, national drug approval number H20020250, half an hour before sleep) are used as required. | Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai Traditional Chinese Medicine Formula Granules Research and Development Project | allergic rhinitis | | | | |
ChiCTR2200065936: Clinical study on reducing the recurrence of chronic spontaneous urticaria with Gubenkangmin prescription |
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| Not yet recruiting | N/A | 282 | | Gubenkangmin prescription ;cetirizine hydrochloride | Guangdong Provincial Hosptial of Chinese Medicine; Guangdong Provincial Hosptial of Chinese Medicine, Guangdong Provincial Hosptial of Chinese Medicine | Chronic urticaria | | | | |
ChiCTR2400089523: Clinical efficacy observation and formulation development of Lianling Zhiyang granule in the treatment of atopic dermatitis (heart fire and spleen deficiency syndrome) |
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| Recruiting | N/A | 80 | | 1 dose of Lianling Antipruritic Granules per day, taken twice for 2 weeks; Tacrolimus ointment, 2x/day, topical for 2 weeks; Cetirizine hydrochloride tablets orally, once per night, 10mg once; 2 weeks in total; Tacrolimus ointment, 2x/day, topical for 2 weeks | The third Hospital affiliated to Beijing University of Chinese Medicine; The third Hospital affiliated to Beijing University of Chinese Medicine, Hospital level project of the Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine | Atopic dermatitis | | | | |
