| oxycodone controlled release / Generic mfg. |
ChiCTR-TRC-11001416: Effects, Safety, and Cost Efficacy of Controlled-Release Oxycodone for Pain Control in Transarterial Chemoembolization Therapy for Patients with Liver Cancers |
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| Completed | 4 | 210 | | 20mg controlled-release oxycodone given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE ;10mg controlled-release oxycodone given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE ;placebo pills (containing 100 mg Vitamin C) given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE | Department of Interventional Radiology, Fudan University, Shanghai Medical College, Zhongshan Hospital; Department of Interventional Radiology, Fudan University, Shanghai Medical College, Zhongshan Hospital, Department of Interventional Radiology, Fudan University, Shanghai Medical College, Zhongshan Hospital | liver cancer | | | | |
2009-017640-13: Continuous peripheral block in the pain and ischemic ulcer treatment in arteriopathy patients |
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| Ongoing | 4 | 76 | Europe | Solution for injection, Prolonged-release tablet, CHIROCAINE*5F 10ML 5MG/ML PPS, OXYCONTIN*28CPR 10MG R.P. | ISTITUTI ORTOPEDICI RIZZOLI | Arteriophaty patients with ischemic pain and/or ulcers | | | | |
| Ongoing | 4 | 60 | Europe | Tablet, oxyContin | University Hospitals Leuven | Post operative pain after total knee replacement | | | | |
2012-001816-42: Opioidien aiheuttama mahasuolikanavan toiminnanhäiriö selkärankaleikkauspotilailla |
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| Ongoing | 4 | 180 | Europe | Tablet, Targiniq, Oxycontin | Kuopion yliopistollinen sairaala | Tutkittavat henkilöt tulevat elektiiviseen selkärankaleikkaukseen. | | | | |
2005-004527-19: Joint pain personalised treatment assessment to investigate the acceptability of modified release oxycontin for managing chronic pain in patients with osteoarthritis of the hip |
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| Ongoing | 4 | 20 | Europe | Paracetamol, OxyContin, Paracetamol, OxyContin, Paracetamol, OxyContin, Paracetamol, OxyContin | MRC Health Services Research Collaboration | Hip Osteoarthritis | | | | |
2006-003151-21: Study to compare the tolerability of slow release oxycodone versus slow release morphine in the treatment of severe cancer pain. The study is geared towards a clinical practice improvement. |
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| Ongoing | 4 | 400 | Europe | oxicodone, Oxycontin 28cpr 10mg R.P., Oxycontin 28cpr 10mg R.P. | ISTITUTO NAZIONALE PER LA CURA TUMORI | Advanced cancer patient with severe cancer pain | | | | |
2007-007877-22: A prospective blinded randomised placebo controlled trial investigating whether oxycodone modified release reduces parenteral opioid use following intermediate thoracic surgery |
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| Ongoing | 4 | 44 | Europe | OxyContin prolonged release tablets 10mg, OxyContin prolonged release tablets 10mg | Royal Brompton & Harefield NHS Trust | The management of acute pain after intermediate thoracic surgery | | | | |
2008-005808-72: Effect of preoperatively administered oxycontin and intraoperative nitrous oxide use on remifentanil-induced analgesia |
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| Ongoing | 4 | 140 | Europe | OSSICODONE CLORIDRATO, OSSICODONE CLORIDRATO | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI | postoperative pain | | | | |
2012-003188-23: Opioidien aiheuttama mahasuolikanavan toiminnanhäiriö keisarileikkauspotilailla |
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| Ongoing | 4 | 90 | Europe | Oxycontin, Targiniq 10/5 mg, N02AA05, N02AA55, Oxycontin 10 mg, Targiniq 10/5 mg depottabletti, Oxycontin 10 mg, Targiniq 10/5 mg depottabletti | Merja Kokki | Keisarileikkauksen jälkeinen kipu | | | | |
2010-018450-12: Optimising pain control after caesarean section - an evaluation if oxycodone can replace morphine and low potency opioids postoperatively. |
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| Ongoing | 4 | 80 | Europe | OxyContin, OxyNorm, 16454, OxyContin 10 mg, OxyContin 20 mg, OxyNorm 5 mg, OxyNorm 10 mg/ml, OxyContin 10 mg, OxyContin 20 mg, OxyNorm 5 mg, OxyNorm 10 mg/ml | Agneta Blanck Olerup | Pain management after elective cesarean section. | | | | |
2016-002379-89: Treatment of acute locomotoric pain in the geriatric patient: comparison of effectiveness and safety between step 2 (weak opioids) and step 3 (strong opioids) pain relief of the WHO-ladder. |
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| Ongoing | 4 | 200 | Europe | Tradonal Retard 50 mg, TRADONAL ODIS 50 mg, OxyNorm Instant 5 mg, OxyContin 5 mg, Capsule, hard, Orodispersible tablet, Modified-release tablet, TRADONAL Retard 50 mg, capsules met verlengde afgifte, hard, TRADONAL ODIS 50 mg orodispergeerbare tabletten., OxyNorm Instant 5 mg, orodispergeerbare tabletten, OxyContin 5 mg, tabletten met verlengde afgifte | Ghent University Hospital, Ghent University Hospital | Acute locomotoric pain in the geriatric patient., Acute locomotoric pain., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
2017-000141-52: The effect of tapentadol and oxycodone on the human pain system Effekten af tapentadol og oxycodon på det humane smertenetværk |
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| Ongoing | 4 | 20 | Europe | Palexia Depot, OxyContin, Modified-release tablet, Palexia Depot, OxyContin | Asbjørn Mohr Drewes, Grünenthal GmBH | Healthy volunteers - pain, Pain, Diseases [C] - Nervous System Diseases [C10] | | | | |
| Not yet recruiting | 4 | 100 | | use oxycodone hydrochloride controlled-release tablets for titration ;use Immediate release morphine for titration | Department of Head and Neck/Thoracic Medical Oncology; The First People's Hospital of Foshan; The First People's Hospital of Foshan, Department of Head and Neck/Thoracic Medical Oncology;The First People's Hospital of Foshan | cancer pain | | | | |
2017-005146-30: See below PREMEDICINERINGSSTUDIEN Blodkoncentrationen av per os tillfört Oxykodon mäts hos 20 kvinnor som sövs och opereras på en dagkirurgisk enhet. Dessutom mäts smärtan efter operationen |
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| Ongoing | 4 | 20 | Europe | Prolonged-release tablet, OxyContin 5 mg depottabletter, OxyContin 10 mg depottabletter | Sahlgrenska universitetssjukhuset, Göteborgs universitet | See below Postoperativ smärta, See below Smärta efter operation, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR1800014268: Effecty and efficacy of hydrochloride oxycodone controlled-release tablets with dose titration at 12h for cancer pain |
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| Recruiting | 4 | 206 | | hydrochloride oxycodone controlled-release tablets with dose titration at 12h for cancer pain ;hydrochloride oxycodone controlled-release tablets with dose titration at 24h for cancer pain | Zhejiang Cancer Hospital; Zhejiang Cancer Hospital, Self-raised funds | Cancer Pain | | | | |
2017-001285-23: A comparison of pain relief and effects on respiration from tapentadol and oxycodone after surgical removal of the uterus. |
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| Not yet recruiting | 4 | 90 | Europe | Tablet, Modified-release tablet, Capsule, hard, Palexia® 50 mg, Palexia depot®, OxyNorm®, OxyContin® | Oslo University Hospital, Oslo University Hospital | Pain after laparoscopic hysterectomy., Pain after surgical removal of the uterus using a minimal invasive surgical technique., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
ChiCTR2100046045: Clinical efficacy evaluation and prevention of adverse reactions in a randomized trial of a combination of three drugs in the treatment of cancerous pudendal neuralgia |
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| Completed | 4 | 51 | | Celecoxib combined with OxyContin and Pregabalin ;OxyContin and Pregabalin | Jilin Province People's Hospital; Jilin Province People's Hospital, Jilin Province Health and Health Technology Innovation Project (2020Z023) | Cancerous pudendal neuralgia | | | | |
ChiCTR2100042972: Comparative study of sufentanil self-controlled analgesic pump and oxycodone hydrochloride controlled-release tablets in the treatment of moderate and severe cancer pain |
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| Completed | 4 | 52 | | sufentanil ;Oxycodone Hydrochloride | Jiangxi Provincial People's Hospital; Jiangxi Provincial People's Hospital, Self-financing | cancer pain | | | | |
NCT06247488: Abuse Potential of HORIZANT With and Without Oxycodone in Healthy, Nondependent Recreational Opioid Users |
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| Completed | 4 | 110 | US | Placebo, matching over-encapsulated capsule, Oxycodone 20 mg, Oxycontin, GE-IR 200 mg, Gabapentin Enacarbil, Horizant, GE-IR 450 mg | Arbor Pharmaceuticals, Inc. | Abuse Potential | 04/23 | 04/23 | | |
NCT03859024: Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty |
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| Completed | 4 | 48 | US | Oxycodone, oxycontin, Acetaminophen, tylenol, Gabapentin, neurontin, celebrex, celecoxib, Bupivacaine, marcaine, exparel, Ibuprofen 800 mg, advil, motrin, Dexamethasone, decadron, ozurdex | University of Alabama at Birmingham | Pain, Postoperative, Urethral Stricture | 04/23 | 06/23 | | |
ChiCTR2200063670: A prospective, double-blind, randomized, placebo-controlled study of Tianchan Capsule combined with Oxycontin in the treatment of pain in advanced colorectal cancer |
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| Not yet recruiting | 4 | 60 | | Xenopus capsule + Oxycontin ;Placebo + OxyContin | Cancer Hospital, Chinese Academy of Medical Sciences; Cancer Hospital, Chinese Academy of Medical Sciences, Research and Evaluation special project of China Association of Traditional Chinese Medicine | Cancer pain in advanced colorectal cancer | | | | |
ChiCTR2200058515: Study on the mechanism of cancer pain treated with Ailitong ointment based on NGS gene polymorphism |
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| Not yet recruiting | 4 | 100 | | Oral Oxycontin ;Oral Oxycontin and external Ailitong ointment | Foshan Hospital of Traditional Chinese Medicine; Foshan Hospital of Traditional Chinese Medicine, Guangdong Administration of Traditional Chinese Medicine | Cancer Pain | | | | |
2009-015943-17: SEQUENTIAL STUDY ON THE INCIDENCE AND INTENSITY OF INTESTINAL CONSTIPATION ASSOCIATED TO OXYCODONE (OXYCONTIN) AND THE COMBINATION OF OXYCODONE/NALOXONE (TARGIN) FOR CHRONIC ONCOLOGIC PAIN TREATMENT (ONCO_PAIN 01/2009). |
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| Ongoing | 3 | 30 | Europe | OXYCONTIN, Targin, OXYCONTIN, Targin | AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI | Advanced neoplastic desease with pain | | | | |
NCT04808531: NanaBis™ an Oro-buccal Administered delta9-Tetrahydrocannabinol (d9-THC) & Cannabidiol (CBD) Medicine for the Management of Bone Pain From Metastatic Cancers |
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| Not yet recruiting | 3 | 360 | NA | NanaBis™, MDCNB-01, NanoCelle® d9-THC & CBD, Oxycodone CR, OxyNorm®, OxyContin®, Endone®, Proladone®, Targin®, Xtampza ER®, Placebo Spray, NanoCelle® Placebo Spray, Placebo Tablet, Oxycodone IR, Oxyfast®, Oxy IR®, Oxaydo®, Roxicodone® | Medlab Clinical, George Clinical Pty Ltd, WriteSource Medical Pty Ltd | Cancer Related Pain | 02/24 | 06/24 | | |
2013-001540-60: A new way of evaluating the adverse effects of opioids on the gut. En ny måde at evaluere opioiders bivirkninger på mavetarmsystemet. |
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| Ongoing | 2/3 | 70 | Europe | OxyContin, Targin, Movicol, OxyContin, Targin, Movicol, OxyContin, Targin, Movicol | Mech-Sense, Aalborg University Hospital, Aalborg University Hospital, The Danish Council for Strategic Research, Mundipharma Research GmbH & Co. KG | Opioid-induced bowel dysfunction. | | | | |
2015-001523-24: Evaluation of the pain relief of prolonged-release oxycodone and of L-Dopa, versus placebo, in Parkinson's disease. Evaluation de la diminution de la douleur liée à la maladie de Parkinson par l'oxycodone à libération prolongée et la L-Dopa versus placebo. |
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| Not yet recruiting | 2/3 | 75 | Europe | Oxycontin LP 5mg, Oxycontin LP 10mg, Oxycontin LP 20mg, Modopar 125, Modopar 62,5, Tablet, Capsule, oxycontin LP 5mg, oxycontin LP 10mg, oxycontin LP 20mg, Modopar 125, Modopar 62,5 | UHToulouse, Ministry of health | Central neuropathic pain in Parkinson's disease douleurs neuropathique liées à la maladie de Parkinson, Pain in parkinson's disease douleurs liées à la maladie de parkinson, Diseases [C] - Nervous System Diseases [C10] | | | | |
2015-000419-42: Naloxegol and assessments of opioid induced bowel dysfunction |
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| Ongoing | 2 | 24 | Europe | Moventig, OxyContin, Film-coated tablet, Prolonged-release tablet, Moventig, OxyContin | Aalborg University Hospital, Astra Zeneca | Healthy volunteers (Opioid-induced bowel dysfunction), Healthy volunteers (Adverse effects of opioids on the gut), Body processes [G] - Digestive System and Oral Physiological Phenomena [G10] | | | | |
2012-003770-11: A multi-center, randomized parallel group pilot study to investigate the mechanism of action of tapentadol PR and oxycodone CR in subjects with osteoarthritis knee pain |
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| Ongoing | 2 | 60 | Europe | Palexia Depot, OxyContin, Palexia Depot, OxyContin | C4Pain ApS, Grünenthal GmbH | Osteoarthritic Knee Pain. | | | | |
NCT06232577: 5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial |
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| Recruiting | 2 | 150 | US | Hydrocodone, Tramadol, Oxycodone, ETH-Oxydose™ [DSC], OxyContin®, OxyIR®, Roxicodone® | M.D. Anderson Cancer Center | Intra-abdominal Cancer | 07/24 | 07/26 | | |
NCT05265052: 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain |
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| Not yet recruiting | 2 | 177 | NA | 3D1002 (50 mg)(Phase IIa), 3D1002 (100 mg)(Phase IIa), 3D1002 (150 mg)(Phase IIa), 3D1002 monotherapy (Phase IIb), OxyContin monotherapy (Phase IIb), 3D1002 + OxyContin (Phase IIb) | 3D Medicines | Cancer Pain | 12/25 | 12/25 | | |
| Recruiting | 2 | 110 | US | Ketorolac, Ketorolac tromethamine, Toradol, Biorolac, Acetaminophen, Tylenol, Oxycodone, Oxycontin, Roxicodone, Hydromorphone, Dihydromorphinone, Dilaudid, Hydromorph Contin, Palladone, Ibuprofen, Advil, Motrin | University of Miami | Kidney Cancer, Renal Cancer, Renal Neoplasm | 09/25 | 09/25 | | |
NCT06484439: Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction |
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| Completed | 1 | 80 | US | Ketorolac, Toradol, Oxycodone, Oxycontin, Acetaminophen, Tylenol, Ibuprofen, Motrin, Hydrocodone, Vicodin | United States Naval Medical Center, San Diego | Pain, Post-operative, Third Molar, Oral Surgery, Pain, Acute | 11/21 | 12/21 | | |
| Completed | 1 | 48 | | OTR 10 mg ;OXYCOTIN 10 mg | Affiliated Hospital of Liaoning University of Traditional Chinese Medicine; Mundipharma (China) Pharmaceutical Co. Ltd., fully self-financing | Chronic Pain | | | | |
ChiCTR1800017253: An Open-label, Single Dose, Randomised, Cross-over Study to Determine the Fasted State pharmacokinetics of Oxycodone from Oxycodone Tamper Resistant (OTR) Tablet 40 mg and OXYCONTIN Tablet 40 mg in Chinese Subjects with Chronic Pain |
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| Not yet recruiting | 1 | 38 | | OTR-OXY ;OXY-OTR | West China Hospital, Sichuan University; Mundipharma (China) Pharmaceutical Co. Ltd, Mundipharma (China) Pharmaceutical Co. Ltd | Chronic pain | | | | |
ChiCTR1800016581: A Retrospective Study to compare Cost and Effectiveness of Intravenous Patient-Controlled Analgesia (IVPCA) Morphine protocol and Preemptive Multimodal Analgesia Oral Etoricoxib and Oxycontin Protocol for Post Total Knee Replacement Patients |
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| Completed | N/A | 102 | | Preemptive Multimodal Analgesia [PMA] regmien and Intravenous Patient-Controlled Analgesia [IVPCA] | Department of Anaesthesia & Intensive Care, Prince of Wales Hospital; Prince of Wales Hospital, Department of Anaesthesia & Intensive Care, PWH | Total Knee Replacement | | | | |
ChiCTR1800016532: Clinical study of Longtengtongluo wine and oxycontin combined with the treatment of cancer pain |
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| Recruiting | N/A | 100 | | Longtengtongluo wine + Three ladder painkillers ;Placebo + Three ladder painkillers | Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai Municipal Committee for health and family planning | Cancer pain | | | | |
ChiCTR2000036789: A randomized controlled trial for Wenyang Sanjie Decoction in the treatment of bone metastasis of lung cancer |
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| Not yet recruiting | N/A | 100 | | Wenyang Sanjie Decoction + zoledronic acid + oxycontin ;zoledronic acid + oxycontin | Longhua Hospital, Shanghai University of Traditional Chinese Medicine; Longhua Hospital, Shanghai University of Traditional Chinese Medicine, hospital development center | bone metastasis of lung cancer | | | | |
