- |||||||||| oxycodone controlled release / generics
Journal: The Opioid Crisis and the Orthopedic Surgeon. (Pubmed Central) - Mar 30, 2019 ...Before the opioid misuse epidemic, orthopedic surgeons were frequently influenced to "treat pain with pain medications." Long-acting opioids, such as OxyContin were used commonly...Third, we will look at perioperative interventions that can reduce postoperative opioid consumption, including wound injections and peripheral nerve blocks, which have shown superb clinical results. Finally, we will recommend an evidence-based program that avoids parenteral narcotics and facilitates rapid discharge home without readmissions for pain-related complaints.
- |||||||||| oxycodone controlled release / generics
Journal: The impact of OxyContin reformulation at the Sydney Medically Supervised Injecting Centre: Pros and cons. (Pubmed Central) - Mar 27, 2019 This study replicates the trend towards substitution of OxyContin® with other opioids following the introduction of reformulated OxyContin® in Australia and extends initial findings by showing the rate of overdose per MSIC visit increased following reformulation. These unintended consequences need to be considered when evaluating the success or otherwise of these kinds of changes in product formulation.
- |||||||||| Trial completion date, Trial primary completion date, Surgery: Pain Management in Head and Neck Surgery Patients (clinicaltrials.gov) - Feb 27, 2019
P4, N=60, Recruiting, Trial completion date: Oct 2019 --> Jun 2019 | Trial primary completion date: Apr 2019 --> Jun 2019 Trial completion date: Jul 2020 --> Nov 2020 | Trial primary completion date: Jun 2019 --> Nov 2019
- |||||||||| oxycodone controlled release / Generic mfg., ibuprofen / Generic mfg.
Biomarker, Trial completion date, Trial primary completion date: Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes (clinicaltrials.gov) - Feb 16, 2019 P4, N=238, Recruiting, Trial completion date: Jul 2020 --> Nov 2020 | Trial primary completion date: Jun 2019 --> Nov 2019 Trial completion date: Nov 2019 --> Nov 2020 | Trial primary completion date: Nov 2018 --> Nov 2019
- |||||||||| risperidone / Generic mfg., oxycodone controlled release / Generic mfg., ziprasidone / Generic mfg.
New P1 trial: Reducing the Abuse of Opioids in Drug Users (clinicaltrials.gov) - Feb 11, 2019 P1, N=25, Not yet recruiting,
- |||||||||| Trial completion date, Trial primary completion date, Surgery: Pain Management in Head and Neck Surgery Patients (clinicaltrials.gov) - Sep 19, 2018
P4, N=60, Recruiting, Phase classification: P1 --> P=N/A Trial completion date: Dec 2019 --> Jul 2020 | Trial primary completion date: Dec 2018 --> Jun 2019
- |||||||||| Gralise (gabapentin) / Alvogen
Trial completion, Trial completion date, Trial primary completion date, HEOR: Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation (clinicaltrials.gov) - Aug 22, 2018 P=N/A, N=60, Completed, Trial completion date: Dec 2019 --> Jul 2020 | Trial primary completion date: Dec 2018 --> Jun 2019 Active, not recruiting --> Completed | Trial completion date: Jan 2022 --> Jun 2018 | Trial primary completion date: Jan 2021 --> Jun 2018
- |||||||||| OxiFast (oxycodone immediate release) / Purdue, Shionogi, Mundipharma
Trial completion date, Trial primary completion date, Surgery: Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway (clinicaltrials.gov) - Aug 16, 2018 P3, N=105, Active, not recruiting, Active, not recruiting --> Completed | Trial completion date: Jan 2022 --> Jun 2018 | Trial primary completion date: Jan 2021 --> Jun 2018 Trial completion date: Aug 2020 --> Jan 2019 | Trial primary completion date: Aug 2020 --> Jan 2019
- |||||||||| oxycodone ER (PF614) / Ensysce Biosciences
Trial completion: Study of PF614 Compared to OxyContin (clinicaltrials.gov) - Jul 26, 2018 P1, N=64, Completed, Not yet recruiting --> Recruiting Recruiting --> Completed
- |||||||||| oxycodone controlled release / Generic mfg.
Trial completion, Phase classification: Early Use of Opioid in Radiation Mucositis (clinicaltrials.gov) - Jul 17, 2018 P2, N=200, Completed, Recruiting --> Completed Not yet recruiting --> Completed | Phase classification: PN/A --> P2
- |||||||||| oxycodone controlled release / Generic mfg.
Trial completion: OTR Tablet 40 mg Fasted-state Bioequivalence Study (clinicaltrials.gov) - Apr 2, 2018 P1, N=38, Completed, Not yet recruiting --> Active, not recruiting | Trial completion date: Jan 2020 --> Apr 2019 | Trial primary completion date: Jan 2019 --> Apr 2019 Recruiting --> Completed
- |||||||||| Palexia RP (tapentadol extended release) / Assertio, J&J, Grunenthal, Collegium Pharma
Enrollment change, Trial withdrawal, Trial primary completion date: An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR) (clinicaltrials.gov) - Jan 25, 2018 P4, N=0, Withdrawn, Trial primary completion date: Jan 2018 --> Sep 2018 | Trial completion date: Jan 2018 --> Sep 2018 N=150 --> 0 | Terminated --> Withdrawn | Trial primary completion date: Apr 2013 --> Aug 2012
- |||||||||| oxycodone ER (PF614) / Ensysce Biosciences
Enrollment open, Enrollment change, Trial primary completion date: Study of PF614 Compared to OxyContin (clinicaltrials.gov) - Dec 5, 2017 P1, N=64, Recruiting, Trial primary completion date: Nov 2017 --> Jun 2018 Completed --> Recruiting | N=48 --> 64 | Trial primary completion date: Apr 2017 --> Jan 2018
- |||||||||| Trial primary completion date, Surgery: Pain Management in Head and Neck Surgery Patients (clinicaltrials.gov) - Nov 22, 2017
P4, N=60, Recruiting, N=130 --> 70 | Trial primary completion date: May 2017 --> May 2018 Trial primary completion date: Aug 2018 --> Dec 2018
- |||||||||| oxycodone controlled release / Generic mfg., ibuprofen / Generic mfg.
Biomarker, Enrollment open, Phase classification, Trial initiation date, Trial primary completion date: Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes (clinicaltrials.gov) - Oct 26, 2017 P4, N=238, Recruiting, Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting | Phase classification: PN/A --> P4 | Initiation date: Nov 2016 --> Jul 2017 | Trial primary completion date: Nov 2017 --> Nov 2018
- |||||||||| Enrollment open, Surgery: Pain Management in Head and Neck Surgery Patients (clinicaltrials.gov) - Sep 14, 2017
P4, N=60, Recruiting, Not yet recruiting --> Recruiting | Phase classification: PN/A --> P4 | Initiation date: Nov 2016 --> Jul 2017 | Trial primary completion date: Nov 2017 --> Nov 2018 Not yet recruiting --> Recruiting
- |||||||||| OxiFast (oxycodone immediate release) / Purdue, Shionogi, Mundipharma
Enrollment closed, Enrollment change, Surgery: Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway (clinicaltrials.gov) - Aug 10, 2017 P3, N=105, Active, not recruiting, Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | N=200 --> 105
- |||||||||| oxycodone ER (PF614) / Ensysce Biosciences
Trial completion: Study of PF614 Compared to OxyContin (clinicaltrials.gov) - Jul 27, 2017 P1, N=48, Completed, Recruiting --> Active, not recruiting | N=200 --> 105 Recruiting --> Completed
- |||||||||| Trial initiation date, Trial primary completion date, Surgery: Pain Management in Head and Neck Surgery Patients (clinicaltrials.gov) - Jun 21, 2017
P4, N=60, Not yet recruiting, Not yet recruiting --> Recruiting | Initiation date: Jan 2016 --> Sep 2016 Initiation date: May 2017 --> Aug 2017 | Trial primary completion date: May 2018 --> Aug 2018
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