- |||||||||| entacapone/levodopa/carbidopa / Generic mfg.
Review, Journal, Real-world evidence, Real-world: Real-world considerations of the use of Stalevo in Parkinson's Disease. (Pubmed Central) - Jul 25, 2023
The hepatotoxicity observed with the class comparator tolcapone has not been observed with entacapone, the COMT inhibitor in LCE, and there is no formal requirement to monitor liver function during LCE therapy. Other common side effects include diarrhoea, which is one of the more prominent non-dopaminergic adverse events, and urine discolouration, which is harmless but about which patients may require reassurance.
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