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What about leronlimab? (Twitter) - Mar 15, 2023
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EFFICACY AND SAFETY OF LERONLIMAB IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS: KEY BIOMARKER RESULTS FROM NASH01 () - Oct 23, 2022 - Abstract #AASLD2022AASLD_1146; These exploratory results show leronlimab significantly reduced mean change in PDFF, cT1, and key inflammatory markers from baseline to week 14 for the 350 mg group and for the moderate and severe fibro-inflammation subgroups. The mechanism of action for leronlimab suggests to be multifactorial, involving VCAM, CCL2, CCL3, CCL11, and CCL18 in addition to competitive binding of CCR5 effecting metabolic and fibro-inflammatory parameters with implications for systemic reductions in vascular permeability, arterial stiffness, and oxidative stress.
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#Leronlimab, Katie 🙏 (Twitter) - Sep 30, 2022
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Sorry leronlimab (Twitter) - Aug 1, 2022
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