- |||||||||| Carafate (sucralfate) / AbbVie
A Rare Case of Kleine-Levin Syndrome Exacerbated by Erosive Esophagitis (Exhibit Hall) - Jul 29, 2023 - Abstract #ACG2023ACG_2392;
Psychiatry initiated treatment with lorazepam and haloperidol...His mental status improved significantly while on pantoprazole and sucralfate...C: EGD findings of LA Grade D erosive esophagitis of the mid esophagus. D: EGD findings of LA Grade D erosive esophagitis of the distal esophagus.
- |||||||||| lorazepam / Generic mfg.
Journal: Refining medical clearance protocol for patients with primary psychiatric complaints in the emergency department. (Pubmed Central) - Jul 26, 2023
Most common intervention was intravenous (IV) fluids (n = 59; 45%) followed by admission to other service (n = 15; 8.4%), imaging (n = 10; 7.6%), antihypertensive medication (n = 3; 3.1%), cardiac workup (n = 3; 2.3%), antibiotics (n = 3; 2.3%), lorazepam for undocumented reasons (n = 2; 1.5%)...Certain laboratory testing such as CK and CMP were identified to have higher utility for medical intervention while other lab work such as UA and UDS had less of an impact. Further, we suggest that specifically a CK and CMP be obtained on patients presenting with any of the following: agitation, abnormal vital signs, intoxication, or a history of or current stimulant use as these were factors correlated with lab abnormalities that led to interventions.
- |||||||||| Here We Go Again: Acromegalic Patient For Repeat Pituitary Tumor Resection (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_1530;
Current medications include metformin, insulin, lisinopril, metoprolol and PRN lorazepam for anxiety, which he admits to using for sleep on occasion.1...Should the patient receive perioperative dexamethasone for PONV prophylaxis?The surgeon begins topicalization of the nasal mucosa using injected lidocaine 1% with epinephrine...What additional labs would you request to determine the diagnosis?15. How would you treat this condition?
- |||||||||| Here We Go Again: Acromegalic Patient For Repeat Pituitary Tumor Resection (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_1182;
Current medications include metformin, insulin, lisinopril, metoprolol and PRN lorazepam for anxiety, which he admits to using for sleep on occasion.1...Should the patient receive perioperative dexamethasone for PONV prophylaxis?The surgeon begins topicalization of the nasal mucosa using injected lidocaine 1% with epinephrine...What additional labs would you request to determine the diagnosis?15. How would you treat this condition?
- |||||||||| Seizalam (midazolam intramuscular) / Pfizer
Journal: Deviation From National Dosing Recommendations for Children Having Out-of-hospital Emergencies. (Pubmed Central) - Jul 10, 2023
We investigated dosing deviations (defined as being ?20% of the weight-appropriate dose from national guidelines) for the following: lorazepam, diazepam, and midazolam for seizures; fentanyl, hydromorphone, morphine, and ketorolac; intramuscular epinephrine and diphenhydramine for children with allergy or anaphylaxis; intravenous epinephrine; and methylprednisolone...Appropriate dosing was most common with methylprednisolone (75.1%), intramuscular epinephrine (67.9%), and ketorolac (56.4%)...We identified variance in weight-based dosing from national guidelines for common pediatric medications in the prehospital setting, which may be attributable to protocol differences or dosing errors. Addressing these should be a target for future educational, quality improvement, and research activities.
- |||||||||| Gammagard Liquid (human normal immunoglobulin 10%) / Takeda
Enrollment open: Therapies for Down Syndrome Regression Disorder (clinicaltrials.gov) - Jul 10, 2023
P2, N=66, Recruiting,
Addressing these should be a target for future educational, quality improvement, and research activities. Not yet recruiting --> Recruiting
- |||||||||| Retrospective data, Journal: Alternative psychopharmacologic treatments for pediatric catatonia: a retrospective analysis. (Pubmed Central) - Jul 3, 2023
In conclusion, all patients responded to these treatments with improvement in their catatonic symptoms. Alternative pharmacologic interventions for catatonia, including benzodiazepines other than lorazepam, valproic acid, NMDA receptor antagonists, and atypical antipsychotics were safe and effective in treating catatonia in this population.
- |||||||||| lorazepam / Generic mfg., haloperidol / Generic mfg., amoxicillin / Generic mfg.
Acute psychotic disorder as a risk factor of bullous pemphigoid: case report () - Jul 3, 2023 - Abstract #WCD2023WCD_5027;
KEY MESSAGE: Hospitalization of BP is related to the psychotic episodes in patients with schizophrenia. This report suggest that acute psychotic disorder may be the independent risk factor of BP, even without prior history of schizophrenia.
- |||||||||| lorazepam / Generic mfg.
Case Report Of Hematidrosis () - Jul 3, 2023 - Abstract #WCD2023WCD_4168;
A trial 2-month prescription of lorazepam, a minor tranquillizer, was given for reducing his anxiety state, and the bleeding disappeared...The use of atropine patches was effective according to one study. Beta blockers and anxiolytic therapy are tried with some relief
- |||||||||| lorazepam / Generic mfg., clonidine / Generic mfg.
Trial initiation date: Premedication for Claustrophobic Patients for MRI Scan (clinicaltrials.gov) - Jun 4, 2023
P=N/A, N=50, Recruiting,
Traditional antiemetic prescribing remains a key barrier to effective management of pediatric CHS. Initiation date: May 2022 --> Jul 2020
- |||||||||| Nourianz (istradefylline) / Kyowa Kirin
Preclinical, Journal: Striatal adenosine A receptor involvement in normal and large nest building deer mice: perspectives on compulsivity and anxiety. (Pubmed Central) - Jun 2, 2023
Our findings indicate that NNB and LNB behavior are not distinctly associated with measures of generalized anxiety and that ISTRA-induced changes in nesting expression are dissociated from changes in anxiety scores. Further, data from this investigation show that nesting in deer mice is directly related to striatal adenosine signaling, and that LNB is founded upon a lower degree of adenosinergic A stimulation.
- |||||||||| lorazepam / Generic mfg.
Journal: The diagnosis and treatment of catatonia. (Pubmed Central) - May 31, 2023
Multidisciplinary working between psychiatrists and physicians is often essential. The main limitation of the guidelines is the low quality of the underlying evidence, comprising mainly small observational studies and case reports or series.
- |||||||||| FASTKD2 gene mutation presenting with status epilepticus evolving to super-refractory status in dizygotic twins (Foyer 3B, 3rd Floor) - May 29, 2023 - Abstract #EPNS2023EPNS_749;
In keeping with guidance, a STT approach using lorazepam was applied in the majority of ArLD patients. Mitochondrial status epilepticus is reported rarely and challenging in terms of management and prognosis.Other than a lateralization difference, this dizygotic twins had identical clinical and radiological findings which further expands the phenotype of FASTKD2 gene mutation.
- |||||||||| Journal, Adverse events: Prescribed Drugs and Self-Directed Violence: A Descriptive Study in the Spanish Pharmacovigilance Database. (Pubmed Central) - May 27, 2023
There were reports of montelukast, hydroxychloroquine, isotretinoin, methylphenidate, infliximab, natalizumab, ribavirin and efavirenz, which were less known to be involved in self-directed violence...It is important for healthcare professionals to consider this risk in their clinical praxis, implementing person-centred approaches. Further studies are needed, considering comorbidities and potential interactions.
- |||||||||| baclofen / Generic mfg., gabapentin / Generic mfg.
Journal: Evaluation of Gabapentin and Baclofen Combination for Inpatient Management of Alcohol Withdrawal Syndrome. (Pubmed Central) - May 24, 2023
Overall, the safety of gabapentin/baclofen vs benzodiazepine were comparable; however, 1 patient experienced a seizure, and 1 patient experienced delirium tremens during admission in the benzodiazepine group. Gabapentin/baclofen combination seems to be an effective and safe alternative to benzodiazepines and may be considered for managing mild AWS in hospitalized patients, but additional research is needed to examine this regimen.
- |||||||||| lorazepam / Generic mfg.
Journal: Resistant Catatonia in a 10-year-old Child: A Case Report. (Pubmed Central) - May 23, 2023
In this case report we discuss about a child who was resistant to both lorazepam and electroconvulsive therapy...Symptomatic treatment, ruling out organic causes, and judicious use of pharmacotherapy can be beneficial in resistant cases. benzodiazepines; case reports; catatonia; electroconvulsive therapy.
- |||||||||| lorazepam / Generic mfg., gabapentin / Generic mfg.
Successful Use of ECT to Eliminate Self-Injurious Behaviors in an Adolescent With Autism Spectrum Disorder (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1465;
Initially, the patient received ECT treatments three days a week and this was successfully decreased to once a week over the course of several months. He continues to receive ECT as further tapering of ECT was not successful due to the re-emergence of self-injurious behaviors.
- |||||||||| olanzapine / Generic mfg., lorazepam / Generic mfg., haloperidol / Generic mfg.
Pica and Coprophagia in Schizophrenia: A Case Report (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1371;
He steadily improved with antipsychotic medication and was discharged 34 days following admission. Recommendations post-discharge included continued medication management and evidence-based psychosocial interventions for schizophrenia.
- |||||||||| lorazepam / Generic mfg., levetiracetam / Generic mfg.
A Case of Anorexia Nervosa With Severe and Rare Medical Complications Illustrates the Need for Collaborative Care (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1325;
Fortunately, orthostasis resulting in fall and subarachnoid hemorrhage did not cause any major harm to this patient but her risk for catastrophic injury remains elevated because of extremely poor nutritional status, dehydration, and electrolyte imbalance. There is evidence that prompt early interventions may prevent the development of irreversible complications, poor insight, and reluctance to seek help remain the major obstacles.
- |||||||||| lorazepam / Generic mfg., sertraline / Generic mfg., quetiapine / Generic mfg.
Urinary Retention in Catatonia: An Atypical Presentation (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1113;
Soon after this was given, the patient became more active, was able to eat and urinate without difficulty, and no longer reported nihilistic delusions His urinary retention resolved after initiation of lorazepam, and he was discharged without residual symptoms on lorazepam 1.5 mg orally three times daily, sertraline, and quetiapine.. Furthermore, certain causes of pain can be symptoms of the patient
- |||||||||| lamotrigine liquid oral suspension / OWP Pharma
Challenges in Management of Catatonia in Patients With Chronic Use of Antipsychotics: Case Report (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1049;
A management dilemma arouses given her chronic use of antipsychotics and the possibility that these drugs may be causing or worsening her symptoms and deteriorating her convulsive and motor disorder. In this poster we discuss the challenge in the approach and management of patients with catatonia who need an antipsychotic as part of the treatment for the underlying condition of a catatonic presentation.
- |||||||||| Benzodiazepines for Suspected Delirious Mania in a Patient With Traumatic Brain Injury (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1048;
While mania is associated with TBI, DM and TBI is seldom reported.3 Though typical antipsychotics can potentially worsen DM, scheduled lorazepam led to rapid clinical improvement in our patient despite recent haloperidol decanoate administration. DM should be considered in patients with acute onset delirium, incontinence or inappropriate toileting, and denudativeness with psychotic symptoms.4 Treatment should include benzodiazepines despite hesitancy to prescribe in patients with TBI.
- |||||||||| Rapid Response to ECT in Post-Operative Induced Catatonia: Case Report and Review of the Literature (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_1013;
DM should be considered in patients with acute onset delirium, incontinence or inappropriate toileting, and denudativeness with psychotic symptoms.4 Treatment should include benzodiazepines despite hesitancy to prescribe in patients with TBI. E is a 76 year-old female with a history of hypothyroidism secondary to Hashimoto
- |||||||||| risperidone / Generic mfg., lorazepam / Generic mfg., sertraline / Generic mfg.
Personalized Digital Treatment and Its Current Use in Mental Health (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_955;
Depending on the course of their disease state, VR therapy may have different effects at different points in time. VRET provides patients with effective, affordable and equitable care which may be applied to vast psychiatric disorders such as PTSD, MDD and/or specific phobias.
- |||||||||| lorazepam / Generic mfg.
Treating Benzodiazepine Resistant Catatonia of Unclear Etiology in an Adolescent? (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_950;
She responded well to a lorazepam challenge...While ECT is the gold standard of treatment for catatonia that does not remit with benzodiazepines, the protocol for treating catatonia in children when ECT is not available is not well defined, especially when the condition underlying the catatonia remains unclear. In this poster, we discuss the options for treating a pediatric patient with benzodiazepine resistant catatonia when the family declines ECT or when ECT is difficult to access.
- |||||||||| Thalamic Strokes Mimicking Extra-Pyramidal Symptoms After Long-Acting Injectable Antipsychotic Administration in a Young Veteran (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_944;
Neurology reviewed a head CT obtained on admission which redemonstrated a stable 2.4cm pontine AVM and showed up to four previously missed bilateral thalamic infarcts.They recommended obtaining an MRI, CT angiogram, and starting the patient on aspirin 81mg daily...was treated with physical therapy and dexamethasone 2mg with a planned taper...was discharged to inpatient physical rehabilitation, and has returned home and continues to improve. In this poster, we discuss the challenges of differentiating stroke deficits from EPS symptoms and stress the importance of collaboration with other specialties in providing comprehensive care to patients with histories of psychiatric illness.
- |||||||||| lorazepam / Generic mfg., escitalopram / Generic mfg.
Speech Impairment Associated With Functional Neurological Disorder, Potential Treatment Targets: A Case Report (Hall B Foyer, Exhibition Level Moscone South) - May 17, 2023 - Abstract #APA2023APA_942;
Patient was started on Escitalopram 10 mg PO QAM and discharged with recommendations to continue with outpatient treatment and psychotherapy...The patient had no other symptoms of catatonia and no improvement with an Ativan challenge...Our case demonstrated that SSRIs can be useful in the treatment of FND, especially in patients experiencing mutism or speech difficulties. More research is needed to study SSRI as a treatment option for mutism associated with FND
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