- |||||||||| Xolair (omalizumab) / Roche, Novartis
A CASE OF HEREDITARY A-TRYPTASEMIA EXACERBATION FOLLOWING SECOND DOSE OF MRNA COVID-19 VACCINE ON OMALIZUMAB (Hall B (1st Floor); Monitor 03) - Nov 2, 2021 - Abstract #ACAAI2021ACAAI_746;
She has since been pre-medicated with antihistamines, famotidine, lorazepam, and fluids prior to omalizumab with good response and significant improvement in symptoms allowing her to taper off cyclosporine and steroids...This case showed exacerbation following second dose of mRNA COVID-19 vaccine (despite tolerating first dose) that likely precipitated reactions following omalizumab. Therefore, omalizumab was able to be safely continued with pre-medication and was effective in controlling symptoms.
- |||||||||| Trial termination, Surgery: Post Operative Pain Control After Pediatric Hip Surgery (clinicaltrials.gov) - Nov 1, 2021
P=N/A, N=42, Terminated,
Therefore, omalizumab was able to be safely continued with pre-medication and was effective in controlling symptoms. Completed --> Terminated; Funding was exhausted prior to enrolling intended number of patients.
- |||||||||| lorazepam / Generic mfg.
Ativan? (Twitter) - Oct 30, 2021
- |||||||||| lorazepam / Generic mfg.
Journal: Lorazepam challenge test for catatonia. (Pubmed Central) - Oct 29, 2021
We present the first case in the literature of the withdrawal manifesting in disturbing obsessive thoughts after the substance was used as an opioid replacement treatment by our patient, as well as the first case where lorazepam is utilized for mitigation of these thoughts. No abstract available
- |||||||||| lorazepam / Generic mfg., midazolam hydrochloride / Generic mfg.
Clinical, Journal: Pneumonia Risk Associated with the Use of Individual Benzodiazepines and Benzodiazepine Related Drugs among the Elderly with Parkinson's Disease. (Pubmed Central) - Oct 27, 2021
In these individuals, incident pneumonia risk was high in users of BZDs, such as midazolam, lorazepam, flunitrazepam, estazolam, and clonazepam. Regarding the use of BZRDs, zopiclone increased incident pneumonia risk.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] Diabetic Striatopathy in a Choctaw Female () - Oct 21, 2021 - Abstract #ANA2021ANA_293;
DS is an uncommon complication of uncontrolled Type II diabetes that can be corrected with gly cemic control and should be considered in presentations of acute hemichorea. Our report is unique as no case report in existence, to our knowledge, presents this rare disorder in a person of Choctaw heritage
- |||||||||| ketamine / Generic mfg., lorazepam / Generic mfg.
[VIRTUAL] Testing the Salzburg Criteria in Cefepime Induced Non-Convulsive Status Epilepticus () - Oct 21, 2021 - Abstract #ANA2021ANA_201;
Initial attempt to classify the pattern as ictal using clinical and EEG improvement from IV anti-seizure medications in this case failed, but both EEG and clinical improvement was seen after 24 hours of IV ketamine infusion. Our report highlights need to quantify the time interval that should be used to define NCSE in the Salzburg criteria through the trial of IV anti-seizure medication.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] The Enigma of Changing Exam During IV Alteplase Administration in Acute Stroke () - Oct 21, 2021 - Abstract #ANA2021ANA_104;
We present a case where patient initially started with left MCA stroke and during alteplase administration, developed right MCA stroke. In conclusion, possibility of a new stroke during alteplase administration should be kept in the differential for change in neurological exam in these patients.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] PROSTACYCLIN'S, PULMONARY HYPERTENSION, AND END OF LIFE CARE () - Oct 13, 2021 - Abstract #CHEST2021CHEST_2287;
There is minimal evidence regarding the use of PC therapy during palliation for patients with advanced PAH. Following the implementation of a Prostacyclin End of Life Titration Protocol, we hope to provide optimal comfort and pain control for end of life PAH patients.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] ALCOHOL WITHDRAWAL AND OVERLAPPING FIBERS: A BRIDGE TO A CORONARY SYNDROME () - Oct 13, 2021 - Abstract #CHEST2021CHEST_1195;
A hyperadrenergic state in conjunction with chronic endothelial injury from alcohol and a coronary muscle bridge, increases significantly the risk for acute coronary syndrome (ACS). Active delirium and medications used for withdrawal may mask the symptoms of ACS, making the diagnosis more challenging.
- |||||||||| lorazepam / Generic mfg., midazolam hydrochloride / Generic mfg.
[VIRTUAL] COVID-19-ASSOCIATED LEUKOENCEPHALOPATHY PRESENTING AS NEW ONSET REFRACTORY STATUS EPILEPTICUS () - Oct 13, 2021 - Abstract #CHEST2021CHEST_705;
CASE PRESENTATION: A 50-year-old Caucasian woman with a past medical history significant for chronic lymphocytic leukemia (CLL) for which she was on umbralisib and venetoclax, was admitted with COVID-19 infection...After several courses of antibiotics, her septic shock was successfully treated with meropenem...Therapy with lorazepam, four doses of 4mg IV, propofol infusion, phosphenytoin and levetiracetam failed to abort the seizures...Lacosamide and midazolam infusion were then sequentially added and were successful in terminating the seizures... This case is unique in that this patient in addition to the depressed mental status typically seen in COVID-19-positive patients who develop leukoencephalopathy, developed new-onset refractory status epilepticus as well.
- |||||||||| [VIRTUAL] A CASE OF STATUS EPILEPTICUS SECONDARY TO BUPROPION OVERDOSE TREATED WITH IV LIPID EMULSION THERAPY () - Oct 13, 2021 - Abstract #CHEST2021CHEST_638;
Her roommate reported finding empty pill bottles of bupropion, gabapentin, and propranolol at her apartment...Salicylates, acetaminophen, and alcohol levels were undetectable...Despite being on lorazepam drip, her seizures continued and were also resistant to phenobarbital, levetiracetam, valproate, fentanyl, and propofol...Positive amphetamines on urine toxicology are expected with bupropion use as their metabolites have chemical structures similar to amphetamine... ILE therapy can be used as an antidote for severe bupropion toxicity.
- |||||||||| diphenhydramine / Generic mfg., lorazepam / Generic mfg.
[VIRTUAL] AGITATED, ALTERED, AND ELONGATED: THE RISKS OF DIPHENHYDRAMINE OVERDOSE () - Oct 13, 2021 - Abstract #CHEST2021CHEST_631;
Initial toxicology was negative for acetaminophen, salicylate and ethanol.NaHCO infusion with goal pH 7.5 to maintain a narrow QRS was started...The use of intravenous DPH, haloperidol and lorazepam can be used to calm acutely agitated or aggressive patients; yet, it should be avoided with unknown ingestions.Further, QT prolongation and polymorphic VT can result from DPH's ability to weakly block the delayed rectifier potassium channels (2)... High suspicion and familiarity with toxidromes can lead to early diagnosis and intervention for critically ill patients presenting with agitated altered mental status.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] ACUTE ACQUIRED MACROGLOSSIA IN REFRACTORY STATUS EPILEPTICUS PATIENT () - Oct 13, 2021 - Abstract #CHEST2021CHEST_545;
After admission, she had multiple seizure episodes responding to Lorazepam...She was started on Levetiracetam but was found to be in non-convulsive status epilepticus on continuous EEG monitoring...Lacosamide was added followed by sodium valproate and fosphenytoin without any improvement... In conclusion, in acute critically ill patients with acute acquired macroglossia, cessation of offending agents, with airway protection is cornerstone.
- |||||||||| lorazepam / Generic mfg.
[VIRTUAL] BIZARRE BEHAVIORS: AUTOIMMUNE ENCEPHALITIS MASQUERADING AS A PSYCHIATRIC SYNDROME () - Oct 13, 2021 - Abstract #CHEST2021CHEST_526;
He received Lorazepam and Levetiracetam...Not being controlled with lorazepam and haloperidol, a Dexmedotomide drip was started.Laboratory data including urine drug screen was unremarkable except elevated CK (3127 U/L)... The differential of NMDA receptor antibody encephalitis must be considered in young patients with neuropsychiatric symptoms as they are often misdiagnosed with psychiatric disorders, which impedes early treatment.The removal of the tumor and immunotherapy generally carry a good prognosis with complete recovery.
- |||||||||| Darzalex IV (daratumumab) / J&J
[VIRTUAL] A "TRYING" CASE OF TRIMETHOPRIM TOXICITY () - Oct 13, 2021 - Abstract #CHEST2021CHEST_523;
It is important to review all medications and recognize uncommon agents, such IV TMP/SMX. PG toxicity can be seen at levels previously thought to be safe.
- |||||||||| ketamine / Generic mfg.
Enrollment change, Trial completion date, Trial primary completion date: Treatment Resistant Depression (Pilot) (clinicaltrials.gov) - Oct 6, 2021
P=N/A, N=110, Active, not recruiting,
Further work is important to understand factors driving prescribing given limited studies surrounding medication prescribing in hospice. N=40 --> 110 | Trial completion date: Jun 2021 --> Jun 2022 | Trial primary completion date: Jun 2021 --> Jun 2022
- |||||||||| lorazepam / Generic mfg.
Clinical, Journal: Potentially inappropriate medication in older psychiatric patients. (Pubmed Central) - Oct 2, 2021
Rational deprescribing of inappropriate anticholinergics, benzodiazepines, and antipsychotics in the older population is a key component to reduce the risk of adverse drug reactions. More tolerable medications should be prescribed.
- |||||||||| lorazepam / Generic mfg.
How to cope with addictions and prescriptions () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4549;
In these cases, protected under the fake feeling of immortality, when they request voluntary discharge, an adequate psychiatric evaluation of their capacities at that time is important, due to the legal repercussions. Unfortunately, and without adequate family support, the prognosis of these patients is not usually good, with premature deaths in most cases
- |||||||||| lorazepam / Generic mfg.
How to cope with addictions and prescriptions () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4548;
In these cases, protected under the fake feeling of immortality, when they request voluntary discharge, an adequate psychiatric evaluation of their capacities at that time is important, due to the legal repercussions. Unfortunately, and without adequate family support, the prognosis of these patients is not usually good, with premature deaths in most cases
- |||||||||| lorazepam / Generic mfg.
How to cope with addictions and prescriptions () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4547;
In these cases, protected under the fake feeling of immortality, when they request voluntary discharge, an adequate psychiatric evaluation of their capacities at that time is important, due to the legal repercussions. Unfortunately, and without adequate family support, the prognosis of these patients is not usually good, with premature deaths in most cases
- |||||||||| lorazepam / Generic mfg.
How to cope with addictions and prescriptions () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4546;
In these cases, protected under the fake feeling of immortality, when they request voluntary discharge, an adequate psychiatric evaluation of their capacities at that time is important, due to the legal repercussions. Unfortunately, and without adequate family support, the prognosis of these patients is not usually good, with premature deaths in most cases
- |||||||||| lorazepam / Generic mfg.
Psychiatric symptoms as a manifestation of a neurological disorder. A case report. () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4173;
Relevance The presence of psychiatric symptoms in a patient presenting to the emergency department is often thought to be the expression of an underlying psychiatric disorder; even though this is not uncorrect, we must always remember that psychiatric symptoms can also be a manifestation of a neurological disorder, such as an encephalopathy. Even though it has not been possible to clearly identify the cause of the encephalopathy in this patient, it is clear that he did not suffer from any psychiatric disturbance, as it was initially suggested, but from a neurological disorder that needed hospitalization and an ad hoc therapy; recognizing a situation as the one described in this case report, is crucial to promptly act to cure the underlying cause and to improve the healing and survival chances of the patient.
- |||||||||| lorazepam / Generic mfg.
Psychiatric symptoms as a manifestation of a neurological disorder. A case report. () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4172;
Relevance The presence of psychiatric symptoms in a patient presenting to the emergency department is often thought to be the expression of an underlying psychiatric disorder; even though this is not uncorrect, we must always remember that psychiatric symptoms can also be a manifestation of a neurological disorder, such as an encephalopathy. Even though it has not been possible to clearly identify the cause of the encephalopathy in this patient, it is clear that he did not suffer from any psychiatric disturbance, as it was initially suggested, but from a neurological disorder that needed hospitalization and an ad hoc therapy; recognizing a situation as the one described in this case report, is crucial to promptly act to cure the underlying cause and to improve the healing and survival chances of the patient.
- |||||||||| lorazepam / Generic mfg.
Psychiatric symptoms as a manifestation of a neurological disorder. A case report. () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4171;
Relevance The presence of psychiatric symptoms in a patient presenting to the emergency department is often thought to be the expression of an underlying psychiatric disorder; even though this is not uncorrect, we must always remember that psychiatric symptoms can also be a manifestation of a neurological disorder, such as an encephalopathy. Even though it has not been possible to clearly identify the cause of the encephalopathy in this patient, it is clear that he did not suffer from any psychiatric disturbance, as it was initially suggested, but from a neurological disorder that needed hospitalization and an ad hoc therapy; recognizing a situation as the one described in this case report, is crucial to promptly act to cure the underlying cause and to improve the healing and survival chances of the patient.
- |||||||||| lorazepam / Generic mfg.
Psychiatric symptoms as a manifestation of a neurological disorder. A case report. () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4170;
Relevance The presence of psychiatric symptoms in a patient presenting to the emergency department is often thought to be the expression of an underlying psychiatric disorder; even though this is not uncorrect, we must always remember that psychiatric symptoms can also be a manifestation of a neurological disorder, such as an encephalopathy. Even though it has not been possible to clearly identify the cause of the encephalopathy in this patient, it is clear that he did not suffer from any psychiatric disturbance, as it was initially suggested, but from a neurological disorder that needed hospitalization and an ad hoc therapy; recognizing a situation as the one described in this case report, is crucial to promptly act to cure the underlying cause and to improve the healing and survival chances of the patient.
- |||||||||| lorazepam / Generic mfg., sertraline / Generic mfg.
Is this mother crazy? () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_3497;
However, with appropriate treatment, most patients are able to lead normal lives with few limitations. For these reasons, we must suspect neurological pathology even when there is psychiatric symptomatology, avoiding underestimate them because of previous medical records.
- |||||||||| lorazepam / Generic mfg., sertraline / Generic mfg.
Is this mother crazy? () - Oct 1, 2021 - Abstract #EUSEM2021EUSEM_3496;
However, with appropriate treatment, most patients are able to lead normal lives with few limitations. For these reasons, we must suspect neurological pathology even when there is psychiatric symptomatology, avoiding underestimate them because of previous medical records.
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