mupirocin / Generic mfg. 
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 25 Diseases   30 Trials   30 Trials   851 News 


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  • ||||||||||  tacrolimus / Generic mfg.
    [VIRTUAL] A Case of Porphyria Cutanea Tarda After Kidney Transplant (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_3138;    
    He was also noted to have cytomegalovirus viremia which was treated with valganciclovir...At presentation his medications included mycophenolate sodium, tacrolimus, prednisone, triamcinolone cream and mupirocin ointment...It has also been associated with hemodialysis often with resolution at the time of kidney transplantation. However, elevated iron stores are often present in kidney transplant patients and PCT can be misdiagnosed as bullous impetigo as it was in this case.
  • ||||||||||  clindamycin phosphate / Generic mfg.
    Enrollment open, Trial initiation date:  Optimal Treatment of MRSA Throat Carriers (clinicaltrials.gov) -  Sep 22, 2020   
    P3,  N=80, Recruiting, 
    2019 has that number down to 13.5%. Not yet recruiting --> Recruiting | Initiation date: Feb 2020 --> May 2020
  • ||||||||||  mupirocin / Generic mfg.
    Trial completion:  Project CLEAR - Changing Lives by Eradicating Antibiotic Resistance (clinicaltrials.gov) -  Sep 17, 2020   
    P=N/A,  N=2140, Completed, 
    The results from this study will provide new clinical and cost-effectiveness evidence to support the best strategy for the prevention of PD-related infections among the Thai PD population. Active, not recruiting --> Completed
  • ||||||||||  Trial completion date, Trial primary completion date:  Checklist to Prevent MRSA Surgical Site Infections (clinicaltrials.gov) -  Aug 25, 2020   
    P=N/A,  N=10748, Recruiting, 
    Active, not recruiting --> Completed Trial completion date: Sep 2020 --> Feb 2021 | Trial primary completion date: Sep 2020 --> Feb 2021
  • ||||||||||  mupirocin / Generic mfg.
    Trial completion date, Trial primary completion date, Surgery:  STAd (clinicaltrials.gov) -  Aug 20, 2020   
    P=N/A,  N=600, Recruiting, 
    Trial completion date: Sep 2020 --> Feb 2021 | Trial primary completion date: Sep 2020 --> Feb 2021 Trial completion date: Apr 2020 --> Apr 2021 | Trial primary completion date: Apr 2020 --> Apr 2021
  • ||||||||||  mupirocin / Generic mfg.
    Trial completion date, Trial primary completion date:  PANCADIPE: Usefulness of Sterile Adhesive Dressing at the Exit-site of Peritoneal Dialysis Catheter (clinicaltrials.gov) -  Jul 21, 2020   
    P=N/A,  N=30, Recruiting, 
    Replacing patient-applied home mupirocin with nurse-applied day-of-surgery decolonization should be assessed in order to facilitate increased compliance. Trial completion date: Jan 2022 --> Jan 2023 | Trial primary completion date: Jan 2020 --> Jan 2021
  • ||||||||||  mupirocin / Generic mfg.
    Enrollment open, Trial primary completion date:  Staph Household Intervention for Eradication (SHINE) (clinicaltrials.gov) -  Jul 2, 2020   
    P4,  N=207, Recruiting, 
    All MRSA VAP were diagnosed before the routine use of mupirocin. Active, not recruiting --> Recruiting | Trial primary completion date: May 2021 --> Aug 2021
  • ||||||||||  mupirocin / Generic mfg.
    Enrollment closed:  Staph Household Intervention for Eradication (SHINE) (clinicaltrials.gov) -  May 11, 2020   
    P4,  N=183, Active, not recruiting, 
    Active, not recruiting --> Recruiting | Trial primary completion date: May 2021 --> Aug 2021 Recruiting --> Active, not recruiting
  • ||||||||||  Trial completion date, Trial primary completion date:  STaph Aureus Resistance-Treat Early and Repeat (STAR-TER) (clinicaltrials.gov) -  May 1, 2020   
    P2,  N=42, Recruiting, 
    Recruiting --> Active, not recruiting Trial completion date: Dec 2020 --> Jun 2022 | Trial primary completion date: Dec 2020 --> Jun 2022
  • ||||||||||  chlorhexidine gluconate / Generic mfg., mupirocin / Generic mfg.
    Enrollment change:  TREAT PARENTS: Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial (clinicaltrials.gov) -  Mar 16, 2020   
    P=N/A,  N=307, Completed, 
    In patients undergoing TKA a preoperative screening and decolonization protocol for S. aureus nasal carriers, using mupirocin nasal ointment and chlorhexidine soap, is an effective measure to reduce the rate of SSI caused by this microorganism. N=236 --> 307
  • ||||||||||  rifampicin / Generic mfg.
    Journal:  Staphylococcus aureus nasal decolonization strategies: a review. (Pubmed Central) -  Mar 14, 2020   
    Some of them are still in preclinical phases, and others have reached clinical trials, but further research is needed. Special interest should be given to single dose decolonization strategies and to molecules that do not select resistant strains.
  • ||||||||||  Silverzine Tulle (Silver Sulfadiazine) / MinaPharm, mupirocin / Generic mfg., Locilex (pexiganan acetate) / PLx Pharma Inc
    Clinical, Journal:  SPS-neutralization in tissue samples for efficacy testing of antimicrobial peptides. (Pubmed Central) -  Feb 25, 2020   
    Special interest should be given to single dose decolonization strategies and to molecules that do not select resistant strains. SPS was successfully used to neutralize residual activity of SAAP-148, pexiganan and chlorhexidine and this prevented an overestimation of their efficacy.
  • ||||||||||  Trial completion date, Trial primary completion date:  Topical Antibiotics in Chronic Rhinosinusitis (clinicaltrials.gov) -  Jan 3, 2020   
    P1/2,  N=40, Recruiting, 
    The increasing use of paid healthcare workers attending patients daily to help perform PD (assisted PD) gives an opportunity for us to address these wider issues. Trial completion date: Jul 2020 --> Jul 2021 | Trial primary completion date: Dec 2019 --> Dec 2020
  • ||||||||||  clindamycin phosphate / Generic mfg.
    Trial initiation date:  Optimal Treatment of MRSA Throat Carriers (clinicaltrials.gov) -  Dec 20, 2019   
    P3,  N=80, Not yet recruiting, 
    No abstract available Initiation date: Nov 2019 --> Feb 2020
  • ||||||||||  cefazolin / generics, vancomycin / generics, mupirocin / generics
    Clinical, Journal:  Multifaceted aseptic protocol decreases surgical site infections following hip arthroplasty. (Pubmed Central) -  Oct 16, 2019   
    The addition of intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples, to a standard bundle of SSI prevention, reduces the incisional and organ-space SSI and consequently the hospital stay, after elective laparoscopic colorectal cancer surgery (ClinicalTrials.gov Identifier: NCT03081962). Our aseptic protocol decreases SSI in a high-risk population undergoing hip arthroplasty in a medical centre and community with a high prevalence of MRSA.
  • ||||||||||  Trial completion date, Trial primary completion date:  Checklist to Prevent MRSA Surgical Site Infections (clinicaltrials.gov) -  Oct 3, 2019   
    P=N/A,  N=10748, Recruiting, 
    Our aseptic protocol decreases SSI in a high-risk population undergoing hip arthroplasty in a medical centre and community with a high prevalence of MRSA. Trial completion date: Sep 2019 --> Sep 2020 | Trial primary completion date: Sep 2019 --> Sep 2020
  • ||||||||||  mupirocin / generics
    Journal:  MSSA screening and decolonisation in elective hip and knee arthroplasty. (Pubmed Central) -  Sep 30, 2019   
    The MSSA screening and eradication protocol used in our institution was effective at reducing rates of MSSA PJI. Furthermore, it resulted in significant savings when compared to the cost of prevented infections.
  • ||||||||||  clindamycin phosphate / Generic mfg.
    New P3 trial:  Optimal Treatment of MRSA Throat Carriers (clinicaltrials.gov) -  Sep 26, 2019   
    P3,  N=80, Not yet recruiting, 
  • ||||||||||  mupirocin / generics
    A Safe, More Cost-Effective Protocol-Universal Decolonization versus MRSA Screening and Contact Precautions (204 ABC) -  Sep 12, 2019 - Abstract #IDWeek2019IDWeek_665;    
    Methods : Prior to the universal decolonization trial, patients at high-risk for MRSA colonization were screened using a nasal polymerase chain reaction (PCR) test, and those that tested positive were decolonized with 5 days of mupirocin nasal ointment and daily CHG bathing, and were placed in CP...There was no statistical change in the MRSA bacteremia rate (.067 to .070) per 1,000 patient days. Conclusion : Replacement of nasal screening, decolonization and CP for colonized MRSA patients with universal decolonization, using twice daily alcohol-based nasal antiseptic paired with daily CHG bathing, was found to be a safe and cost-saving protocol.
  • ||||||||||  mupirocin / Generic mfg.
    Phase classification:  DERAIL_MRSA: Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities (clinicaltrials.gov) -  Sep 11, 2019   
    P=N/A,  N=22302, Completed, 
    Conclusion : Replacement of nasal screening, decolonization and CP for colonized MRSA patients with universal decolonization, using twice daily alcohol-based nasal antiseptic paired with daily CHG bathing, was found to be a safe and cost-saving protocol. Phase classification: P4 --> P=N/A
  • ||||||||||  chlorhexidine gluconate / generics, mupirocin / generics
    Journal, HEOR:  Cost-effectiveness of pre-operative Staphylococcus aureus screening and decolonization. (Pubmed Central) -  Sep 11, 2019   
    We predict that the treat-all strategy would be the most effective and cost-saving strategy for preventing SSIs. However, because this strategy might select more extensively for mupirocin-resistant S. aureus and cause more medication adverse effects than the test-and-treat approach or the SOC, additional studies are needed to define its comparative benefits and harms.
  • ||||||||||  mupirocin / generics
    Implementation of a Staphylococcus aureus screening and decolonization program in a multisite urban healthcare system () -  Aug 26, 2019 - Abstract #IDWeek2019IDWeek_1351;    
    aureus decolonization (mupirocin ointment in nares twice daily, chlorhexidine 2% wipes below the chin daily for 5 days) began in 2017 for patients with central venous catheter, in intensive care unit or multibedded room...The MRSA bacteremia rate fell from 0.2/1000 patient days in the first half of 2018 to 0.1/1000 patient days in the second half of 2018. Conclusion : A system-wide program that includes S. aureus screening and decolonization of hospitalized patients found that 21% of patients had S. aureus colonization. Screening and decolonization compliance increased with introduction of a dedicated clinical nurse specialist, and the MRSA bloodstream infection rate fell.
  • ||||||||||  mupirocin / Generic mfg.
    Enrollment closed, Head-to-Head:  Mupirocin-Iodophor ICU Decolonization Swap Out Trial (clinicaltrials.gov) -  Aug 14, 2019   
    P4,  N=137, Active, not recruiting, 
    Implementation of strict infection control measures is essential in dialysis units to avoid MRSA cross-transmission and invasive infections. Recruiting --> Active, not recruiting