- |||||||||| Kadcyla (ado-trastuzumab emtansine) / Roche, Perjeta (pertuzumab) / Roche
New P2 trial, Combination therapy, Heterogeneity: T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA (clinicaltrials.gov) - Dec 30, 2014 P2, N=160, Not yet recruiting,
- |||||||||| Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Trial primary completion date, IO biomarker, Metastases: Vaccine Therapy in Treating Patients With Metastatic Solid Tumors (clinicaltrials.gov) - Dec 6, 2014 P1, N=36, Recruiting, Trial primary completion date: Jan 2015 --> Jan 2016 Trial primary completion date: Oct 2014 --> Jan 2015
- |||||||||| Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Trial completion, Enrollment change, Trial primary completion date, Metastases: Use of PRO Onc Assay to Assess HER2 in Patients With Metastatic Breast Cancer (clinicaltrials.gov) - Nov 28, 2014 P=N/A, N=293, Completed, Trial primary completion date: Oct 2014 --> Jan 2015 Active, not recruiting --> Completed | N=450 --> 293 | Trial primary completion date: Aug 2016 --> Jul 2014
- |||||||||| Myocet (non-pegylated liposomal doxorubicin) / Teva, Sopherion, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment open: SOLTI-Opti-HER: Study of Neoadjuvant Myocet (clinicaltrials.gov) - Oct 15, 2014 P2, N=83, Recruiting, Recruiting --> Active, not recruiting Active, not recruiting --> Recruiting
- |||||||||| Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment closed, Metastases: Paclitaxel, Trastuzumab, and Pertuzumab in the Treatment of Metastatic HER2-Positive Breast Cancer (clinicaltrials.gov) - Sep 12, 2014 P2, N=69, Active, not recruiting, Trial primary completion date: Jun 2014 --> Feb 2015 Recruiting --> Active, not recruiting
- |||||||||| Trial primary completion date, Tumor mutational burden, PD(L)-1 Biomarker, Metastases: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors (clinicaltrials.gov) - Jul 23, 2014
P2a, N=500, Recruiting, Recruiting --> Active, not recruiting Trial primary completion date: Aug 2019 --> Jan 2020
- |||||||||| Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Trial primary completion date: NSABP Biospecimen Discovery Project (clinicaltrials.gov) - Jul 21, 2014 P=N/A, N=50, Recruiting, Trial primary completion date: Aug 2019 --> Jan 2020 Trial primary completion date: Mar 2014 --> Aug 2014
- |||||||||| Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment open, Trial initiation date, Combination therapy, Metastases: BERENICE: A Study Evaluating Pertuzumab (Perjeta) Combined With Trastuzumab (Herceptin) and Standard Anthracycline-based Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced, Inflammatory, or Early-stage Breast Cancer (clinicaltrials.gov) - Jul 1, 2014 P2, N=400, Recruiting, Initiation date: Sep 2014 --> Jun 2014 Not yet recruiting --> Recruiting | Initiation date: Sep 2014 --> Jun 2014
- |||||||||| Trial primary completion date, Tumor mutational burden, PD(L)-1 Biomarker, Metastases: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors (clinicaltrials.gov) - May 18, 2014
P2a, N=500, Recruiting, Initiation date: May 2014 --> Sep 2014 Trial primary completion date: Jan 2020 --> Aug 2019
- |||||||||| Trial completion date, Tumor mutational burden, PD(L)-1 Biomarker, Metastases: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors (clinicaltrials.gov) - May 18, 2014
P2a, N=500, Recruiting, Trial primary completion date: Jan 2020 --> Aug 2019 Trial completion date: Jan 2020 --> Aug 2019
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