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23 Diseases |  |
181 Trials |
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181 Trials |  |
4948 News |  |
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- |||||||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Roche
New P3 trial: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2) (clinicaltrials.gov) - Feb 1, 2014
P3, N=787, Active, not recruiting, Sponsor: Hoffmann-La Roche
- ||| Enrollment closed, Combination therapy: ROMULUS: A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or Obinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) (clinicaltrials.gov) - Jan 26, 2014
P2, N=124, Active, not recruiting, Sponsor: Genentech
Recruiting --> Active, not recruiting
- |||||||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Roche
New P3 trial: CLL11: A Study of RO5072759 (GA101) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Jan 12, 2014
P3, N=787, Active, not recruiting, Sponsor: Hoffmann-La Roche
- |||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Trial completion, Monotherapy: A Dose-Escalating Study of Obinutuzumab in Patients With B-lymphocyte Antigen (CD20+) Malignant Disease (GAUGUIN) (clinicaltrials.gov) - Jan 12, 2014
P2, N=134, Completed, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Roche
Trial initiation date: Phase II Randomized Trial Comparing GA101 and Rituximab in Untreated Low Tumor Burden Indolent Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Dec 15, 2013
P2, N=150, Recruiting, Sponsor: PrECOG, LLC.
Active, not recruiting --> Completed Initiation date: Aug 2013 --> Dec 2013
- |||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment open: Phase II Randomized Trial Comparing GA101 and Rituximab in Untreated Low Tumor Burden Indolent Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Dec 15, 2013
P2, N=150, Recruiting, Sponsor: PrECOG, LLC.
Initiation date: Aug 2013 --> Dec 2013 Not yet recruiting --> Recruiting
- |||||||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Roche
New P3 trial: CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b) (clinicaltrials.gov) - Nov 28, 2013
P3, N=787, Active, not recruiting, Sponsor: Hoffmann-La Roche
- |||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment open, Combination therapy: A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Nov 25, 2013
P3, N=800, Recruiting, Sponsor: Hoffmann-La Roche
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P1/2 trial: Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma (clinicaltrials.gov) - Nov 24, 2013
P1/2, N=72, Not yet recruiting, Sponsor: M.D. Anderson Cancer Center
- ||| Polivy (polatuzumab vedotin-piiq) / Roche, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment open, Combination therapy: A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Nov 24, 2013
P1, N=90, Recruiting, Sponsor: Genentech
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment closed: CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b) (clinicaltrials.gov) - Nov 24, 2013
P3, N=787, Active, not recruiting, Sponsor: Hoffmann-La Roche
Not yet recruiting --> Recruiting Not yet recruiting --> Active, not recruiting
- ||| Polivy (polatuzumab vedotin-piiq) / Roche, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
New P1 trial, Combination therapy: A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Nov 21, 2013
P1, N=90, Recruiting, Sponsor: Genentech
- || Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment closed, Combination therapy: GAUDI: A Study of Obinutuzumab in Combination With Chemotherapy in Participants With CD20+ B-Cell Follicular Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Nov 12, 2013
P1, N=137, Active, not recruiting, Sponsor: Hoffmann-La Roche
Not yet recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- |||||||||| Zydelig (idelalisib) / Gilead
New P3 trial, Combination therapy: Efficacy and Safety of Idelalisib in Combination With Obinutuzumab Compared to Chlorambucil in Combination With Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Nov 7, 2013
P3, N=176, Not yet recruiting, Sponsor: Gilead Sciences
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment closed: A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease (clinicaltrials.gov) - Oct 27, 2013
P1, N=48, Active, not recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- ||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment closed: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) (clinicaltrials.gov) - Oct 20, 2013
P3, N=787, Active, not recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- ||| Venclexta (venetoclax) / Roche, AbbVie, Walter and Eliza Hall Institute, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment open, Combination therapy: A Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participants With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL) (clinicaltrials.gov) - Sep 16, 2013
P1, N=70, Recruiting, Sponsor: Genentech
Recruiting --> Active, not recruiting Suspended --> Recruiting
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Trial initiation date: An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Aug 25, 2013
P4, N=0, Approved for marketing, Sponsor: Genentech
Suspended --> Recruiting Initiation date: May 2013 --> Aug 2013
- ||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Biomarker, Enrollment closed, Combination therapy, Metastases: A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER) (clinicaltrials.gov) - Aug 25, 2013
P2, N=100, Active, not recruiting, Sponsor: Genentech
Initiation date: May 2013 --> Aug 2013 Recruiting --> Active, not recruiting
- ||| Venclexta (venetoclax) / Roche, AbbVie, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment open, Combination therapy: A Study of Venetoclax in Combination With Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Aug 13, 2013
P1, N=70, Recruiting, Sponsor: Genentech
Recruiting --> Active, not recruiting Suspended --> Recruiting
- |||||||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P3 trial, Combination therapy: A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Jul 21, 2013
P3, N=800, Recruiting, Sponsor: Hoffmann-La Roche
- ||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Roche
New P2 trial: Phase II Randomized Trial Comparing GA101 and Rituximab in Untreated Low Tumor Burden Indolent Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Jun 26, 2013
P2, N=150, Recruiting, Sponsor: PrECOG, LLC.
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P4 trial: An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Jun 3, 2013
P4, N=0, Approved for marketing, Sponsor: Genentech
- |||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Trial completion, Monotherapy: GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma (clinicaltrials.gov) - May 22, 2013
P2, N=197, Completed, Sponsor: Hoffmann-La Roche
Suspended --> Recruiting Active, not recruiting --> Completed
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment open: Study of OBINUTUZUMAB Combined to LENALIDOMIDE for the Treatment of Relapsed/Refractory Follicular and Aggressive B-cell Lymphoma (clinicaltrials.gov) - Jan 8, 2013
P1/2, N=200, Recruiting, Sponsor: The Lymphoma Academic Research Organisation
Active, not recruiting --> Completed Active, not recruiting --> Recruiting
- ||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment closed: A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) (clinicaltrials.gov) - Nov 11, 2012
P2, N=80, Active, not recruiting, Sponsor: Genentech
Active, not recruiting --> Recruiting Recruiting --> Active, not recruiting
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Trial initiation date: Study of OBINUTUZUMAB Combined to LENALIDOMIDE for the Treatment of Relapsed/Refractory Follicular and Aggressive B-cell Lymphoma (clinicaltrials.gov) - Oct 1, 2012
P1/2, N=200, Recruiting, Sponsor: The Lymphoma Academic Research Organisation
Recruiting --> Active, not recruiting Initiation date: Jun 2012 --> Oct 2012
- |||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Biomarker, Enrollment open: GAINED: GA In NEwly Diagnosed Diffuse Large B Cell Lymphoma (clinicaltrials.gov) - Sep 30, 2012
P3, N=670, Recruiting, Sponsor: The Lymphoma Academic Research Organisation
Initiation date: Jun 2012 --> Oct 2012 Not yet recruiting --> Recruiting
- ||||| New P2 trial, Combination therapy: ROMULUS: A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or Obinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) (clinicaltrials.gov) - Sep 23, 2012
P2, N=124, Active, not recruiting, Sponsor: Genentech
- ||| Venclexta (venetoclax) / Roche, AbbVie, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P1 trial, Combination therapy: A Study of Venetoclax in Combination With Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (clinicaltrials.gov) - Sep 12, 2012
P1, N=70, Recruiting, Sponsor: Genentech
- | Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P1 trial: A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease (clinicaltrials.gov) - Sep 5, 2012
P1, N=48, Active, not recruiting, Sponsor: Hoffmann-La Roche
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Enrollment closed, Combination therapy: A Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GALTON) (clinicaltrials.gov) - Aug 27, 2012
P1, N=41, Active, not recruiting, Sponsor: Genentech
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- || Venclexta (venetoclax) / Roche, AbbVie, Walter and Eliza Hall Institute, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment change, Combination therapy: A Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participants With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL) (clinicaltrials.gov) - Aug 23, 2012
P1, N=70, Recruiting, Sponsor: Genentech
Recruiting --> Active, not recruiting N=7070 --> 70
- ||| Venclexta (venetoclax) / Roche, AbbVie, Walter and Eliza Hall Institute, Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
New P1 trial, Combination therapy: A Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participants With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL) (clinicaltrials.gov) - Aug 22, 2012
P1, N=70, Recruiting, Sponsor: Genentech
- |||||||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Biomarker, New P3 trial: GAINED: GA In NEwly Diagnosed Diffuse Large B Cell Lymphoma (clinicaltrials.gov) - Aug 5, 2012
P3, N=670, Recruiting, Sponsor: The Lymphoma Academic Research Organisation
- ||| New P1 trial, Combination therapy: Phase 1b Safety and Efficacy Study of TRU-016 (clinicaltrials.gov) - Jul 17, 2012
P1, N=56, Active, not recruiting, Sponsor: Emergent Product Development Seattle LLC
- | Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P1/2 trial: Study of OBINUTUZUMAB Combined to LENALIDOMIDE for the Treatment of Relapsed/Refractory Follicular and Aggressive B-cell Lymphoma (clinicaltrials.gov) - Apr 19, 2012
P1/2, N=200, Recruiting, Sponsor: The Lymphoma Academic Research Organisation
- Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Trial initiation date, Combination therapy: A Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GALTON) (clinicaltrials.gov) - Mar 20, 2012
P1, N=41, Active, not recruiting, Sponsor: Genentech
N=7070 --> 70 Initiation date: Mar 2011 --> Jun 2011
- ||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
Biomarker, New P2 trial, Combination therapy, Metastases: A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER) (clinicaltrials.gov) - Aug 9, 2011
P2, N=100, Active, not recruiting, Sponsor: Genentech
- ||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku
New P2 trial: A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) (clinicaltrials.gov) - Aug 9, 2011
P2, N=80, Active, not recruiting, Sponsor: Genentech
- |||||| Gazyva (obinutuzumab) / Roche, Biogen, Nippon Shinyaku, Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Enrollment open, Combination therapy: A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA) (clinicaltrials.gov) - Aug 9, 2011
P3, N=1400, Recruiting, Sponsor: Hoffmann-La Roche
Initiation date: Mar 2011 --> Jun 2011 Not yet recruiting --> Recruiting