| methylprednisolone acetate / Generic mfg. |
| Ongoing | 4 | 704 | Europe | Methylprednisolone acetate, Triamcinolone acetonide, Injection, Solution for injection, Depo-Medrone, Kenalog | University of Oxford, NIHR Health Technology Assessment Programme | Pulmonary Hypertension, Right heart failure | | | | |
2010-021061-72: To evaluate the safety and efficacy of a single subconjunctival injection of methylprednisolone versus standard postoperative steroid regiment in terms of intraocular inflammation and intraocular pressure following uncomplicated phacoemulsification surgery. |
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| Ongoing | 4 | 50 | Europe | Eye drops, suspension, Suspension for injection, Isopto-Maxidex, Depo-Medrol injektionsvätska. | Ögonkliniken, Akademiska sjukhuset i Uppsala | Att studera säkerheten och effekten av en engångs subkonjunktival injektion med metylprednisolon jämfört med sedvanliga postoperativa kortisonbehandling med ögondroppar avseende intraokulär tryckstegring och intraokulär inflammation efter en okomplicerad kataraktoperation. | | | | |
2004-004591-37: Efficacy of intrarticular steroid injection in osteoarthritis of the first carpometacarpal joint (CMCJ). |
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| Ongoing | 4 | 154 | Europe | METHYLPREDNISOLONE ACETATE 40mg, Bupivocaine Hydrochloride 0.5%, DEPO-MEDRONE, Marcain, DEPO-MEDRONE, Marcain | Leeds teaching Hospitals | Osteoarthritis of the 1st carpometacarpal joint (CMCJ) | | | | |
2007-004947-31: Injectie van autologe bloedplaatjes bij epicondylitis lateralis |
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| Ongoing | 4 | 100 | Europe | corticosteroid, Depo-Medrol met Lidocaïne, | Biomet Nederland BV | Tennis elbow, also known as lateral epicondylitis | | | | |
2010-022106-40: Longterm Effects of Intraarticular Hyaluronan vs Corticosteroid in Osteoarthritis of the Hip: A Randomized Controlled Trial |
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| Ongoing | 4 | 300 | Europe | Depomedrol, RVG 00605, Depomedrol, Depomedrol | | coxarthrosis | | | | |
2011-003207-37: COMPARISON BETWEEN INTRA-ARTICULAR INJECTION OF CORTICOSTEROIDS AND INTRA-ARTICULAR INJECTION OF HYALURONIC ACID IN THE TREATMENT OF ROTATOR CUFF TENDINOPATHY. A PROSPECTIVE CLINICAL TRIAL. CONFRONTO TRA TERAPIA INFILTRATIVA CON CORTICOSTEROIDI E TERAPIA INFILTRATIVA CON ACIDO IALURONICO NEL TRATTAMENTO DELLA TENDINOPATIA DELLA CUFFIA DEI ROTATORI. STUDIO CLINICO PROSPETTICO RANDOMIZZATO |
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| Ongoing | 4 | 92 | Europe | ORTHOVISC SIR 2ML 15MG/ML 1PZ, DEPOMEDROL*1FL 40MG 1ML, ORTHOVISC SIR 2ML 15MG/ML 1PZ, DEPOMEDROL*1FL 40MG 1ML | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI, Policlinico Universitario Agostino Gemelli | ROTATOR CUFF TENDINOPATHY tendinopatia cuffia dei rotatori | | | | |
2016-001906-41: A randomised control trial of knee injections for relief of pain in osteoarthritis: A comparison of corticosteroid and NSAID injections |
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| Ongoing | 4 | 78 | Europe | Ketorolac Trometamol, Methylprednisolone Acetate, SUB02835MIG, SUB03255MIG, Solution for injection, Ketorolac Trometamol, Depo-medrone (Methylprednisolone Acetate) | Royal College of Surgeons in Ireland, Dept of Orthopaedic Surgery, MRHT, Tullamore, Co Offaly | Knee osteoarthritis is the condition of interest. Osteoarthritis is a common musculoskeletal complaint, with an underlying pathogenesis related to bio-mechanical stress loading, resulting in initial changes within the articular cartilage, progressing to develop cartilage fibrillation; vertical clefts and eventual exposure of subchondral bone and eburnation, Knee osteoarthritis is the condition of interest, which is a condition characterised by the wearing down of the protective cartilage within the knee, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2018-001085-42: POISE - Psoriatic Oligoarthritis Intervention with Symptomatic thErapy |
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| Not yet recruiting | 4 | 60 | Europe | Methylprednisolone acetate BP, Triamcinolone acetonide, Injection, Methylprednisolone acetate BP, Triamcinolone acetonide | University of Oxford, NIHR | Psoriatic Arthritis (PsA) is an inflammatory arthritis. PsA is a highly heterogenous disease with a proportion of participants having mild non-progressive disease. Well validated prognostic factors in PsA can identify these Participants including number of active joints, systemic inflammation levels, radiographic damage and functional ability at presentation. There is little research addressing outcomes and treatment options for mild disease., Psoriatic arthritis causes inflammation in and around the joints. It usually affects people who already have psoriasis, a skin condition that causes a red, scaly rash., Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2018-004205-12: Methylprednisolone injection in treatment of birch pollen induced allergic rhinitis |
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| Not yet recruiting | 4 | 60 | Europe | Depo-medrol, Injection, Depo-Medrol® Injektionsvätska, suspension 40 mg/ml | Region Skåne, Region Skåne | Seasonal birch pollen induced allergic rhinitis, Pollen allergy, Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09] | | | | |
2020-002285-14: Effectiveness of corticosteroid injection in treatment of trigger fingers: a double blinded randomized clinical trial |
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| Not yet recruiting | 4 | 300 | Europe | depo-medrol, Kenacort, Kenacort-40, 8719497000913, Injection, Concentrate for solution for injection, Solution for injection, - Depo-Medrol: ATC code H02AB04 – Methylprednisolone: RVG code 00605, Kenacort-10 H02AB08 - Triamcinolone acetonide RVG code 01591, Kenacort-40 H02AB08 - Triamcinolone acetonide RVG code 05341 | JEROEN BOSCH HOSPITAL, Jeroen Bosch Hospital | Trigger finger (stenosing tenosynovitis) is one of the most common conditions seen by hand surgeons,Although not a severe disease, trigger fingers give disabling complaints in performance of work and ADL activities. The triggering is caused by a size mismatch between the first annular pulley (A1) and the corresponding flexor tendon sheath, but the precise etiology still remains unclear.2-4 Most often, trigger fingers do not resolve spontaneously and need some kind of treatment., A triggerfinger is a disease of the flexor tendon tunnel. It is too narrow due irritation that causes difficulty of the tendon to move in the tunnel., Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
NCT04622917: Methylprednisolone Injections Treating Birch Pollen Induced Allergic Rhinitis. |
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| Completed | 4 | 44 | Europe | MethylPREDNISolone 40 Mg/mL Injectable Suspension, Depo-Medrol, NaCl 9 MG/ML Injectable Solution, Sodium Chloride | Karolinska Institutet | Rhinitis, Allergic, Seasonal, Hay Fever, Pollen Allergy, Allergic Rhinitis | 06/22 | 05/23 | | |
NCT04757740: Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint Dysfunction |
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| Completed | 4 | 94 | RoW | intra-articular Platelet rich fibrin and lidocaine, Platelet rich fibrin Group, methylprednisolone acetate and lidocaine, Steroid group | Fayoum University Hospital | Low Back Pain | 09/22 | 03/23 | | |
NCT06268704: Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection |
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| Recruiting | 4 | 230 | US | Dexamethasone, Ozurdex, Maxidex, DexPak, Methylprednisolone, Solu-medrol, Depo-Medrol, Medrol, 2% Lidocaine HCl Injection, Lignocaine, Xylocaine | University of New Mexico | Sacroiliac Joint Dysfunction, Sacro-Iliac Spondylosis | 01/25 | 05/25 | | |
NCT02283996: Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment |
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| Recruiting | 4 | 260 | US | Physical Therapy, Depot Methylprednisolone, Depo Medrol | Massachusetts General Hospital | Adhesive Capsulitis, Frozen Shoulder, Shoulder Frozen | 12/26 | 12/27 | | |
NCT04177433: The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint |
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| Recruiting | 4 | 90 | Canada | Depo-Medrol Injectable Product, Saline | University of Alberta | Osteoarthritis of the Carpometacarpal Joint, Thumb Osteoarthritis | 12/24 | 12/24 | | |
NCT03661645: Post-operative Methylprednisolone Taper Course for Orthopedic Surgery |
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| Enrolling by invitation | 4 | 1000 | US | 10 mg IV dexamethasone & 6 day oral methylprednisolone taper, Medrol, Depo-Medrol, Solu-Medrol, A-Methapred, Decadron, Dexasone, Diodex, Hexadrol, Maxidex, 10 mg IV dexamethasone | Emory University | Orthopedic Surgeries | 01/25 | 01/25 | | |
| Recruiting | 4 | 80 | US | Depo-Medrol, Gel-Flow NT | Hardeep Singh, Society for Minimally Invasive Spine Surgery | Muscle Weakness, Pain, Postoperative, Paresthesia, Pain, Muscle | 08/25 | 05/27 | | |
| Ongoing | 3 | 148 | Europe | Triamcinolone acetonide, Methylprednisolone acetate, Levobupivacaine hydrochloride, Dexamethasone, Bupivacaine hydrochloride, Lidocaine, Suspension for injection, Solution for injection, Chirocaine, lidocaine | The Walton Centre NHS Foundation Trust, NIHR Health Technology Assessment | Chronic radicular pain secondary to a prolapsed intervertebral disc herniation, Sciatica secondary to a prolapsed disc, Body processes [G] - Bones and nerves physological processes [G11] | | | | |
2006-005856-33: Local Glucocorticoid Injektion in the Treatment of Benign Oesophageal Strictures, a Randomized Clinical Study |
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| Ongoing | 3 | 60 | Europe | Depo-Medrol, Depo-Medrol | The Department of Molecular Medicin and Surgery, P9:03, Karolinska Institutet | Patients with benign oesophageal strictures and symptoms where dilatation of the stricture is planned. | | | | |
2018-002224-17: Greater occipital nerve block for a sooner en and better treatment of cluster headache Zenuwblokkade van de grote achterhoofdszenuw voor een snellere en betere behandeling van clusterhoofdpijn |
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| Not yet recruiting | 3 | 80 | Europe | Methylprednisolonacetaat, Injection, Depo-Medrol 40 mg/ml, suspensie voor injectie | Leids Universitair Medisch Centrum, Hersenstichting, Innovatiefonds zorgverzekeraars | Episodic cluster headache, Episodic cluster headache, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT03511625: The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis |
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| Active, not recruiting | 3 | 6 | US | Acthar Injectable Product, repository corticotropin injection, H.P. Acthar Gel, Depo medrol, methylprednisolone acetate injectable suspension | Attune Health Research, Inc., Mallinckrodt | Rheumatoid Arthritis | 02/20 | 12/24 | | |
GRAAPH2014, NCT02611492: A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults |
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| Recruiting | 3 | 265 | Europe | Nilotinib, Methotrexate, Aracytine (Ara C), Granulocyte Colony-Stimulating Factor (G-CSF), Depomedrol, Dexamethasone, Vincristine, Imatinib, 6 Mercaptopurine (6MP) | Assistance Publique - Hôpitaux de Paris | Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia | 12/20 | 12/25 | | |
NCT04980105: Intra-articular Injections of Platelet-rich Plasma, Hyaluronic Acid, or Corticosteroids for Knee Osteoarthritis |
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| Active, not recruiting | 3 | 150 | RoW | Platelet-rich plasma, Hyaluronic acid, Methylprednisolone acetate injectable suspension (DEPO-MEDROL®) | University of Wasit | Osteoarthritis, Knee | 09/21 | 10/21 | | |
NCT04791202: Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis |
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| Not yet recruiting | 3 | 130 | NA | Dextrose, Methylprednisolone Acetate 40 MG/ML | Christine M. Kleinert Institute for Hand and Microsurgery, Kleinert, Kutz and Associates | Pain, Satisfaction, Patient, Functionality | 03/22 | 07/22 | | |
NCT05058287: Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression |
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| Recruiting | 3 | 150 | US | Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo | Hospital for Special Surgery, New York | Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back | 12/24 | 12/24 | | |
NCT06532318: Comparative Study Between Platelet Rich Plasma and Steroid Injection in Trigger Finger Treatment |
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| Not yet recruiting | 3 | 40 | NA | Platelet rich plasma, Pfizer Depo-medrol | Obafemi Awolowo University Teaching Hospital | Trigger Finger Disorder | 12/24 | 06/25 | | |
NCT06045013: Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone in Carpal Tunnel Syndrome |
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| Recruiting | 3 | 70 | RoW | 5% dextrose injection, 5% dextrose, 5% dextrose injections with methylprednisolone acetate 40 mg/ml, Depo-Medrol 40 mg/ml | General and Veteran Hospital Croatian Pride Knin, Clinical Hospital Centre Zagreb, School of Public Health Andrija Štampar | Carpal Tunnel Syndrome | 01/26 | 08/26 | | |
2008-001871-31: Local steroid injection in the treatment of idiopathic carpal tunnel syndrome: A randomized double-blind placebo-controlled trial among patients planned for surgical treatment |
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| Ongoing | 2/3 | 90 | Europe | Depo-Medrol, Xylocain, Depo-Medrol, Xylocain | Region skåne- Hässleholms sjukvårdsorganisation | Neurography verified Carpal tunnel syndrome | | | | |
NCT04942002: Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial |
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| Recruiting | 2/3 | 50 | RoW | Methylprednisolone Acetate 40 MG/ML [Depo-Medrol], Experimental: Standard treatment + intervention, Placebo Comparator: Standard treatment + placebo, 1. Standard treatment + placebo | Asociación para Evitar la Ceguera en México | Optic Neuritis, Treatment, Methylprednisolone | 06/23 | 09/23 | | |
2007-007793-29: Efficacy of long acting steroids intramuscular therapy in nephrotic syndrome: pilot study. |
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| Ongoing | 2 | 29 | Europe | DEPOMEDROL, DEPOMEDROL | ISTITUTO GIANNINA GASLINI | NEPHROSIC SYNDROME | | | | |
NCT03913702: Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement |
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| Terminated | 2 | 1 | US | Ketorolac Tromethamine, Toradol, Methylprednisolone Acetate, DepoMedrol | The University of Texas Medical Branch, Galveston | Subacromial Impingement, Subacromial Impingement Syndrome | 11/22 | 11/22 | | |
| Recruiting | 2 | 250 | US | Bupivacaine-Liposomal Bupivacaine, Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate | Yale University, Department of Anesthesiology Faculty Development Fund | Total Knee Replacement, Knee Arthroplasty | 03/25 | 03/26 | | |
| Recruiting | 2 | 66 | US | Bupivacaine-Liposomal Bupivacaine, B-LB, Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate, B-DEX-MPA | Yale University, Department of Anesthesiology Faculty Development Fund | Total Knee Replacement, Knee Arthroplasty | 03/25 | 03/26 | | |
| Terminated | 2 | 1 | US | Infliximab, Remicade, Intravenous Immunoglobulin Therapy, Gamma Globulin, Gamma Globulin Therapy, Immune Globulin, Immune Globulin Therapy, Intravenous Immunoglobulin, IVIG, Prednisone, Deltasone, Orasone, Meticorten, Panasol-S, Liquid-Pred, Methylprednisolone, Methylprednisolone sodium succinate (Solu-Medrol), methylprednisolone acetate (Depo-Medrol), Methylprednisolone (Medrol) | ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI) | Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Steroid-Refractory Pneumonitis | 12/23 | 12/23 | | |
NCT04467450: Ultrasound Guided Botulinum Toxin Type A Injection of Subacromial-Subdeltoid Bursa in Hemiplegic Shoulder Pain |
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| Recruiting | 1 | 36 | RoW | botulinum toxin type A, botox 100 IU, Methyl Prednisolonate, Depomedrol 40mg /2ml | Benha University | Subacromial Bursitis, Subdeltoid Bursitis | 11/20 | 12/20 | | |
NCT04532775: Efficacy Of Magnesium In Radicular Pain When Added To Local Anesthetics And Steroids In Transforaminal Epidural Injection |
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| Not yet recruiting | 1 | 100 | NA | magnesium, magnesium sulphate, Methylprednisolone, depomedrol, Bupivacaine Hydrochloride, marcaine, saline 0.9%, isotonic solution | Fayoum University | Neuropathy, Pain | 12/20 | 12/20 | | |
NCT04051203: Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia |
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| Completed | 1 | 35 | Canada | Autologous Platelet Rich Plasma Injection, Depo-Medrol and lidocaine, Normal Saline | University of Calgary | Occipital Neuralgia, Headache | 12/23 | 12/23 | | |
NCT06209606: Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma |
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| Not yet recruiting | 1 | 30 | NA | Ruxolitinib Oral Tablet [Jakafi], Ruxolitinib, Jakafi, Lenalidomide, Revlimid, Methylprednisolone, Depo-Medrol, Solu-Medrol, Methyl Prednisolonate | Oncotherapeutics, Incyte Corporation | Multiple Myeloma | 05/26 | 02/29 | | |
I-RUX-15-04, NCT03110822: A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients |
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| Recruiting | 1 | 134 | US | Ruxolitinib Oral Tablet [Jakafi], Ruxolitinib, Jakavi, Lenalidomide, Revlimid, Methylprednisolone, Depo-Medrol, Solu-Medrol, Methyl Prednisolonate | Oncotherapeutics, Incyte Corporation | Multiple Myeloma | 09/24 | 02/27 | | |
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NCT02539394: Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion |
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| Completed | N/A | 128 | NA | Methylprednisolone Acetate, Depo-Medrol, Hemostatic Matrix Kit | Hospital for Special Surgery, New York | Cervical Disc Herniation, Cervical Degenerative Disc Disease, Cervical Spondylotic Myelopathy, Dysphagia, Osteoarthritis of Cervical Spine | 11/20 | 11/21 | | |
NCT04593706: Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars) |
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| Not yet recruiting | N/A | 40 | NA | Betamethasone acetate + Betamethasone sodium phosphate, Dexamethasone sodium phosphate, Methylprednisolone acetate, Triamcinolone acetonide | Tel-Aviv Sourasky Medical Center | Keloid, Hypertrophic Scar, Scars, Scarring | 10/21 | 10/21 | | |
NCT04681937: Comparison of Hyaluronic Acid, PRP and Steroid Injections in Partial Rotator Cuff Tears: A Prospective Randomized Study |
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| Not yet recruiting | N/A | 80 | RoW | Subacromial Injection (hyaluronic acid) + Physical Therapy., Subacromial Injection (Platelet-Rich-Plasma) + Physical Therapy., Subacromial Injection (methylprednisolone acetate) + Physical Therapy., Subacromial Injection (Serum Saline) + Physical Therapy. | Bezmialem Vakif University | Partial Tear of Rotator Cuff, Rotator Cuff Tears | 11/21 | 09/22 | | |
NCT04938037: Comparison of the Efficacy of Two Different Suprascapular Nerve Block Techniques in Patients With Chronic Shoulder Pain |
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| Recruiting | N/A | 80 | RoW | US guided, SSNB with 1ml methylprednisolone acetate (1ml / 40mg) and 5 ml 0.5% bupivacaine | TC Erciyes University | Chronic Shoulder Pain | 06/22 | 06/22 | | |
NCT05971004: Effectiveness of Hydrolyzed Collagen Peptide Injection for the Treatment of Collateral Ligament Pain |
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| Completed | N/A | 62 | RoW | Arthrys (Collagen Peptide solution), Depo medrol | Tiss'You srl | Collateral Ligament Injury of Stifle Joint | 10/22 | 04/23 | | |
| Completed | N/A | 48 | RoW | Methylprednisolone Injection, Depomedrol, Bupivacaine Hcl 0.5% Inj_#2, Marcaine 0.5%, normal saline, 0.9% saline | Menoufia University | Postoperative Pain | 11/23 | 11/23 | | |
NCT05765266: ACP Max™ PRP System for Knee Osteoarthritis: A Feasibility Trial |
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| Recruiting | N/A | 45 | US | ACP Max™, Depo-Medrol®, methylprednisolone acetate) | Arthrex, Inc. | Knee Osteoarthritis | 05/25 | 05/26 | | |
NCT05914350: Comparison Between Ultrasound Guided Ozone, Platelet-Rich Plasma or Steroid Injection in the Treatment of Sacroiliitis; a Randomized Double Blinded Controlled Study |
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| Recruiting | N/A | 105 | RoW | ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis, methylprednisolone acetate and lidocaine, PRP and lidocaine, medical ozone | Tanta University | the Efficacy of Ultrasound Guided Sacroiliac Injection of Ozone, Platelet Rich Plasma (PRP) or Steroid for Treatment of Sacroiliitis | 03/25 | 03/25 | | |
NCT05048264: Effect of Corticosteroid Injections on Blood Glucose |
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| Recruiting | N/A | 55 | US | Kenalog 40 MG, Triamcinolone acetonide, Dexamethasone 4mg, Celestone, Betamethasone, Depo-medrol, Methylprednisolone | Duke University | Diabetes Mellitus, Steroid Diabetes, Shoulder Osteoarthritis, Knee Osteoarthritis, Adhesive Capsulitis, Hip Osteoarthritis | 10/24 | 10/24 | | |
| Recruiting | N/A | 142 | Europe | Lidocaine, Methylprednisolone Acetate, Depo-Medrol, Dexamethasone | C.L.A.Vleggeert-Lankamp, Spaarne Gasthuis, Stichting Achmea Gezondheidszor, Posthumus Meyjes Fonds | Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy | 12/25 | 07/26 | | |
