- |||||||||| aripiprazole / Generic mfg., risperidone / Generic mfg.
Trial completion date, Trial primary completion date: LAP01: Long-term Antipsychotic Pediatric Safety Trial (clinicaltrials.gov) - Sep 6, 2023
P=N/A, N=509, Active, not recruiting,
National Institute on Aging. Trial completion date: Sep 2024 --> Jan 2024 | Trial primary completion date: Sep 2024 --> Jan 2024
- |||||||||| risperidone / Generic mfg.
A case of trichotillomania as the preceding symptom of Huntington () - Aug 30, 2023 - Abstract #MDSCongress2023MDS_Congress_994;
TTM is an obsessive-compulsive disorder characterized by uncontrollable, self-inflicted hair pulling resulting in noticeable hair loss. Since it is a very rare psychiatric manifestation of HD, we presented this case to keep TTM in mind as a possible preceding symptom of HD, and to emphasize the potential positive effect of risperidone in the treatment of TTM and choreic movements in HD.
- |||||||||| Trintellix (vortioxetine) / Lundbeck, Takeda
Journal: The effect of vortioxetine on anhedonia in patients with schizophrenia. (Pubmed Central) - Aug 30, 2023
This is the first report of parkinsonism due to CCM located in SN. The combination of olanzapine and vortioxetine was found to be the best option to reduce symptoms of social and physical anhedonia in these patients with remitted schizophrenia.
- |||||||||| risperidone / Generic mfg., sertraline / Generic mfg.
Dermatozoic delirium or Ekbom syndrome : about two cases (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_4358;
Dermatozoic delirium or Ekbom syndrome often presents psychosocial morbidity. It remains a difficult nosological entity to classify from a dermatological point of view, requiring multidisciplinary management to ensure patient information, disease control and psychological support.
- |||||||||| risperidone / Generic mfg., fluocinolone acetonide / Generic mfg.
Morgellons Disease with Neurotic Excoriation: A Little-Known Disorder of Psychodermatology (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_4334;
In approaching psychodermatology patients, dermatologists need to build good patient-doctor rapport since these patients often deny the psychiatry problem as the cause of their skin condition. Collaborative management with the psychiatry department is essential in managing psychodermatology patients.
- |||||||||| risperidone / Generic mfg., propranolol / Generic mfg.
Hematohidrosis versus Munchausen's syndrome: diagnostic challenges in pediatric dermatology (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_4162;
In reported cases, anxiety or emotional stress were common precipitating events. The pathophysiology is poorly understood, but the main hypothesis proposes possible constriction of blood vessels around the affected sweat glands during intense stress.
- |||||||||| Clinical, Review, Journal, Adverse events: Metabolic Adverse Effects of Psychotropic Drug Therapy: A Systematic Review. (Pubmed Central) - Aug 25, 2023
As for antipsychotics, drugs like Clozapine, Olanzapine, and Risperidone were linked to weight gain, diabetes, and deterioration of the lipid profile...Future research should focus on conducting field studies to further expand knowledge on the metabolic effects of other commonly prescribed psychotropic drugs. Overall, the study highlights the significance of understanding and managing metabolic alterations induced by psychopharmacological treatment to enhance patient care and well-being.
- |||||||||| risperidone / Generic mfg.
Enrollment open, Trial initiation date: PSI-RIS: Does Psilocybin Require Psychedelic Effects to Treat Depression? (clinicaltrials.gov) - Aug 24, 2023
P2, N=60, Recruiting,
Sexual dysfunction is prevalent among patients with schizophrenia spectrum disorder receiving either typical or atypical antipsychotics. Not yet recruiting --> Recruiting | Initiation date: Feb 2023 --> Jul 2023
- |||||||||| risperidone / Generic mfg.
Successful airway management on the patient with spastic torticollis (South: Hall F) - Aug 23, 2023 - Abstract #ASA2023ASA_5163;
A 15-year-old woman with mental retardation developed spastic torticollis after taking risperidone...The epiglottis could not be visualized using the McGrath X blade. Transnasal fiberscopic intubation could be performed without difficulty.
- |||||||||| risperidone / Generic mfg., naltrexone / Generic mfg.
Journal: The Impact of Post-Processing Temperature on PLGA Microparticle Properties. (Pubmed Central) - Aug 17, 2023
Policy makers may consider this approach to improve patient outcomes and budget sustainability. The study highlights the importance of both the post-treatment process and control during manufacturing to obtain a formulation within the desired product profile.
- |||||||||| risperidone / Generic mfg.
Preclinical, Journal, IO biomarker: Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing. (Pubmed Central) - Aug 14, 2023
This was reflected on the cellular level where risperidone impeded VPA-induced oxidative/nitrosative stress and neurodegenerative changes. In conclusion, the present study confirms a possible role for Adar2 downregulation and the subsequent hypo-editing of the GluA2 subunit in the pathophysiology of the prenatal VPA rat model of autism and highlights the favorable effect of risperidone on reversing the RNA editing machinery deficits, giving insights into a new possible mechanism of risperidone in autism.
- |||||||||| risperidone / Generic mfg.
Journal: Association Between Lower Extremity Edema and Risperidone in an Older Adult. (Pubmed Central) - Aug 11, 2023
In conclusion, the present study confirms a possible role for Adar2 downregulation and the subsequent hypo-editing of the GluA2 subunit in the pathophysiology of the prenatal VPA rat model of autism and highlights the favorable effect of risperidone on reversing the RNA editing machinery deficits, giving insights into a new possible mechanism of risperidone in autism. No abstract available
- |||||||||| aripiprazole / Generic mfg.
Journal: Aripiprazole-Associated Rhabdomyolysis in a 17-Year-Old Male. (Pubmed Central) - Aug 10, 2023
In the child and adolescent age group, routine blood tests should be done before starting medication. Symptoms that appear to be nonspecific and that may be overlooked or may be thought to be caused by an existing psychiatric complaint should be carefully and thoroughly considered during follow-up.
- |||||||||| risperidone / Generic mfg.
Journal: Risperidone-induced respiratory depression in a neonate through breast milk. (Pubmed Central) - Aug 9, 2023
The Naranjo Adverse Drug Reaction Probability Assessment Scale scored to 8 which suggests probable relation between the drug and its reaction in neonates. It underscores cautious use in mothers and close monitoring of neonates when risperidone is prescribed irrespective of dosage.
- |||||||||| risperidone / Generic mfg.
Journal: Clinical predictors of psychotropic medication prescription in children with ASD of the ELENA cohort. (Pubmed Central) - Aug 7, 2023
Psychotropic drugs are often used to treat behavior problems in ASD with some evidence supporting efficacity (e.g.: risperidone and irritability) but also significant side effects at the short and longer-term...Low IQ and parents who had received training tended to increase the risk of psychotropic medication prescription during follow-up but were not statistically significant. These findings underscore the need for early identification of symptoms of externalizing behaviour, early appropriate information for parents about treatment with and without medication, early analysis of externalising behaviour and targeted treatments.
- |||||||||| risperidone / Generic mfg., olanzapine / Generic mfg., haloperidol / Generic mfg.
Journal: Antipsychotics Affect Satellite III (1q12) Copy Number Variations in the Cultured Human Skin Fibroblasts. (Pubmed Central) - Aug 2, 2023
The f-SatIII content in DNA positively correlated with RNASATIII content in RNA and with DNA oxidation marker 8-oxodG, while negatively correlated with LC3 content. The antipsychotics arrest the process of f-SatIII repeat augmentation in cultured skin fibroblasts via the transcription suppression and/or through upregulated elimination of cells with enlarged f-SatIII blocks with the help of autophagy.
- |||||||||| risperidone / Generic mfg.
Journal: Converting From Intramuscular to Oral Risperidone in a Nursing Home Resident. (Pubmed Central) - Aug 1, 2023
The antipsychotics arrest the process of f-SatIII repeat augmentation in cultured skin fibroblasts via the transcription suppression and/or through upregulated elimination of cells with enlarged f-SatIII blocks with the help of autophagy. No abstract available
- |||||||||| risperidone / Generic mfg., olanzapine / Generic mfg.
Preclinical, Journal: Near-Infrared Fluorescent Probe for the In Situ Visualization of Oxidative Stress in the Brains of Neuroinflammatory and Schizophrenic Mice. (Pubmed Central) - Aug 1, 2023
Enabling fluorescence monitoring of the dynamic changes in O flux due to the prolonged activation of microglia in neuroinflamed and schizophrenic (SZ) mice brains, thereby providing direct evidence for the relationship between oxidative stress, neuroinflammation, and schizophrenia. Furthermore, we confirmed the O burst in the brains of first-episode schizophrenic mice and assessed the effect of two atypical antipsychotic drugs (risperidone and olanzapine) on redox homeostasis.
- |||||||||| clozapine / Generic mfg.
Trial initiation date: An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine (clinicaltrials.gov) - Aug 1, 2023
P4, N=60, Not yet recruiting,
Furthermore, we confirmed the O burst in the brains of first-episode schizophrenic mice and assessed the effect of two atypical antipsychotic drugs (risperidone and olanzapine) on redox homeostasis. Initiation date: Mar 2023 --> Aug 2023
- |||||||||| Epidiolex (cannabidiol) / Jazz
Trial completion date, Trial primary completion date: Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use (clinicaltrials.gov) - Aug 1, 2023
P2, N=130, Recruiting,
Initiation date: Mar 2023 --> Aug 2023 Trial completion date: Aug 2024 --> Jun 2025 | Trial primary completion date: May 2024 --> Dec 2024
- |||||||||| risperidone / Generic mfg.
Journal, IO biomarker: Short-term treatment with risperidone ameliorated 1,2-diacetylbenzene-induced liver dysfunction. (Pubmed Central) - Jul 27, 2023
The physicochemical characteristics and pharmacokinetics of DAB and risperidone also support the toxic effects of DAB and the beneficial properties of risperidone in the liver. In conclusion, these findings reflect the therapeutic effects of risperidone on DAB-induced liver dysfunction after 1
- |||||||||| risperidone / Generic mfg.
Biomarker, Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia (clinicaltrials.gov) - Jul 27, 2023
P4, N=47, Completed,
In conclusion, these findings reflect the therapeutic effects of risperidone on DAB-induced liver dysfunction after 1 Recruiting --> Completed | N=90 --> 47 | Trial completion date: Oct 2023 --> May 2023 | Trial primary completion date: Oct 2023 --> May 2023
- |||||||||| aripiprazole / Generic mfg., risperidone / Generic mfg.
Journal: Clinical effect of modified electroconvulsive therapy on schizophrenia. (Pubmed Central) - Jul 10, 2023
The application of MECT in patients with schizophrenia can produce a good clinical curative effect, which is beneficial to the improvement and promotion of memory and cognitive functions in patients. Since the occurrence of adverse reactions is controllable, and safety is ideal, MECT has value in clinical application.
- |||||||||| risperidone / Generic mfg., galantamine hydrobromide / Generic mfg., rivastigmine / Generic mfg.
Retrospective data, Journal: Pharmacological treatment of neuropsychiatric symptoms of dementia: a network meta-analysis. (Pubmed Central) - Jul 3, 2023
No abstract available Despite the scarcity of high-quality evidence, risperidone is probably the best pharmacological option to consider for alleviating NPS in people with dementia in short-term treatment when considering the risk-benefit profile of drugs.
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