 |
5 Diseases |  |
67 Trials |
|
67 Trials |  |
4266 News |  |
| «12...3031323334353637383940...6364» |
- || risperidone / Generic mfg.
Clinical, Journal: Psychosis in a primary hyperparathyroidism patient with mild hypercalcemia: A case report. (Pubmed Central) - Apr 7, 2021
Psychiatric symptoms may be the only salient symptoms in PHPT, and thus clinicians should suspect PHPT in patients with psychiatric symptoms and mild hypercalcemia. Furthermore, PTX is recommended for PHPT-even in the presence of severe uncontrolled psychiatric symptoms, which carries risks for postoperative management-because psychiatric symptoms are expected to improve and good postoperative management is possible.
- || Clinical, Review, Journal: Atypical Antipsychotics and Metabolic Syndrome: From Molecular Mechanisms to Clinical Differences. (Pubmed Central) - Apr 7, 2021
The new AAPs such as ziprasidone, lurasidone and the partial agonist aripiprazole seem more tolerable on the metabolic profile...Finally, a multidisciplinary approach combining psychoeducation and therapeutic drug monitoring (TDM) is proposed as a first-line strategy to avoid the MetS. In addition, pharmacological treatments are discussed as well.
- || risperidone / Generic mfg., lurasidone oral / Generic mfg., ziprasidone / Generic mfg.
Clinical, Journal: An Emulation of Randomized Trials of Administrating Antipsychotics in PTSD Patients for Outcomes of Suicide-Related Events. (Pubmed Central) - Apr 7, 2021
In addition, olanzapine was associated with higher SREs than quetiapine and risperidone, and ziprasidone was associated with higher SREs than risperidone. The results of this study suggest that certain antipsychotics may put individuals within the PTSD population at an increased risk of SREs, and that careful consideration may need to be taken when prescribed.
- || Review, Journal: Anticonvulsant and antipsychotic medications in the pharmacotherapy of panic disorder: a structured review. (Pubmed Central) - Apr 7, 2021
The small-to-modest sample size, the lack of control groups and the open-label and short-term nature of most of the reviewed studies hinder definitive conclusions regarding either the short-term and long-term efficacy of antipsychotic and anticonvulsant medications or their potential long-term side effects. Some atypical antipsychotic and anticonvulsant medications may have a role in the treatment of some PD patients, mostly when more conventional approaches have not been successful, but the quality of supporting evidence is limited.
- risperidone / Generic mfg.
[VIRTUAL] Readmission Rates of Patients Discharged from Adult Psychiatric Facilities Prescribed a Second Generation Long-acting Injectable Antipsychotic Compared to the Oral Formulation () - Apr 4, 2021 - Abstract #CPNP2021CPNP_229;
Subgroup analysis will be completed to determine differences in readmission rates based on psychiatric diagnosis and reason for readmission. Outcomes: The authors will report the number and percent of patients readmitted within one year of discharge and analyze whether there is a difference based on diagnoses, concomitant psychotropic medications, reason for readmission, medication formulation, and previous psychiatric hospitalizations.
- risperidone / Generic mfg., methamphetamine / Generic mfg.
[VIRTUAL] Readmission Rates for Methamphetamine-Positive Patients Receiving Long-Acting Injectable Antipsychotics (LAIAs) () - Apr 4, 2021 - Abstract #CPNP2021CPNP_228;
The primary objective will be measured using regression models to examine whether PP or AL is associated with decreased 30-day readmission. Outcomes: This study will report the number and percent of MA-positive patients readmitted within 30 days, the overall time to readmission, and the number and percent of MA-negative UTox results at readmission and compare the results between PP and AL groups.
- risperidone / Generic mfg., sertraline / Generic mfg., carbamazepine / Generic mfg.
[VIRTUAL] Psychiatric Drug-Nutrient Interactions Of Vitamin D: A Retrospective Study () - Apr 4, 2021 - Abstract #CPNP2021CPNP_225;
Fluoxetine, fluvoxamine, haloperidol, olanzapine, risperidone, and sertraline did not have an interaction with calcitriol. The simulation data will be used to retrospectively analyze patient vitamin D and psychiatric drug interactions to understand the risk ratios.
- risperidone / Generic mfg.
[VIRTUAL] Initiation of Antipsychotic Treatment for Amphetamine Induced Psychosis and its Impact on Length of Stay () - Apr 4, 2021 - Abstract #CPNP2021CPNP_211;
Background: Approximately 1.9 million people used methamphetamine in 2018, per the National Survey on Drug Use and Health...However, antipsychotics are commonly used for symptoms of AIP, with aripiprazole, haloperidol, quetiapine, olanzapine, and risperidone being the most commonly cited in the literature...Outcomes: We will evaluate whether initiation of an antipsychotic will impact LOS compared to patients who were not. We hypothesize antipsychotic treatment will decrease LOS by at least one day.
- risperidone / Generic mfg.
[VIRTUAL] Impact of Non-traditional vs Traditional Initiation Dosing Schedule of Paliperidone Palmitate on Readmission and Safety () - Apr 4, 2021 - Abstract #CPNP2021CPNP_200;
Outcomes: We will report differences in the number of readmissions to an ITF within 30 days of regimen completion, number of days until next admission, and length of stay during hospitalization of injectable administration. Secondary outcomes will include differences in the number of readmissions to an ITF within 6 months and the percent of patients who experience adverse events post-injection.
- risperidone / Generic mfg.
[VIRTUAL] Evaluation of Atypical Long-Acting Injectable Antipsychotics for Substance-Induced Psychosis in a Veteran Population () - Apr 4, 2021 - Abstract #CPNP2021CPNP_180;
Small randomized controlled trials and case studies demonstrate that antipsychotics are efficacious in treating inhalant-, methamphetamine-, and alcohol-induced psychosis...Although there is literature to support the use of LAIAs for SIPD, to our knowledge there are no studies comparing the atypical LAIAs risperidone intramuscular extended release suspension, aripiprazole monohydrate, and monthly paliperidone palmitate... In progress.
- risperidone / Generic mfg.
[VIRTUAL] Assessment of Monitoring for Orthostatic Hypotension in Adults 60 Years and Older Being Treated with Select Antipsychotics at an Academic Medical Center. () - Apr 4, 2021 - Abstract #CPNP2021CPNP_85;
Outcomes: By April 18, 2021, we will report the number of elderly patients assessed for OH while being treated with select antipsychotics and any fall-related outcomes. Data provided by this pilot study is intended to be used to inform future interventions that psychiatric pharmacists could make to increase awareness of these higher risk patients.
- risperidone / Generic mfg.
[VIRTUAL] Quality of Patient Care by Converting to Injectable Antipsychotics with Longer Duration of Actions During COVID-19 Pandemic () - Apr 4, 2021 - Abstract #CPNP2021CPNP_12;
There were no significant adverse safety outcomes, with very few psychiatric decompensations directly attributable to the conversion. This proactive approach to patient care represents a new practice strategy for the psychiatric pharmacy specialty.
- ||||| risperidone / Generic mfg.
Clinical: ... UNC then paid off this “holistic” shrink to try to diagnose me w/psychosis, try to put me on ridiculously high doses of lithium & Risperidone, & threaten to institutionalize me, all to continue to try to suppress my crucial research from getting out https://t.co/vhrQKgFqE5 (Twitter) - Apr 3, 2021
- risperidone / Generic mfg., ziprasidone / Generic mfg.
[VIRTUAL] Second-Generation Antipsychotics and Medical Comorbidity: A Retrospective, Cross-Sectional Exploratory Study in an Urban Outpatient Psychiatry Clinic () - Apr 3, 2021 - Abstract #SIRS2021SIRS_1142;
While this study is limited by its retrospective, cross-sectional design, it suggests that future research is warranted to prospectively study the association between ziprasidone and aripiprazole in the development of cardiometabolic comorbidities. Moreover, future studies are warranted to examine the association between antipsychotics, comorbidity, and psychotic symptom scales in this patient population.
- risperidone / Generic mfg., ziprasidone / Generic mfg.
[VIRTUAL] Second-Generation Antipsychotics and Medical Comorbidity: A Retrospective, Cross-Sectional Exploratory Study in an Urban Outpatient Psychiatry Clinic () - Apr 3, 2021 - Abstract #SIRS2021SIRS_1124;
While this study is limited by its retrospective, cross-sectional design, it suggests that future research is warranted to prospectively study the association between ziprasidone and aripiprazole in the development of cardiometabolic comorbidities. Moreover, future studies are warranted to examine the association between antipsychotics, comorbidity, and psychotic symptom scales in this patient population.
- ||| risperidone / Generic mfg., blonanserin / Generic mfg.
Journal, Adverse events: Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments. (Pubmed Central) - Apr 2, 2021
In in vitro experiments, antipsychotics did not promote MCF-7 cell proliferation whereas blonanserin suppressed MCF-7 cell growth. Further research on the effects of blonanserin on the onset and progression of breast tumor is expected.
- || methylphenidate tablet / Generic mfg., risperidone / Generic mfg.
Review, Journal: Hair analysis of antidepressants and antipsychotics - overview of quantitative data. (Pubmed Central) - Apr 1, 2021
A harmonization on the investigated hair lengths as well as on the extraction protocol would be of favor to achieve better comparability. Although hair analysis research focused mainly on drugs abuse, contribution of more data on antidepressants and antipsychotics would help to gain better knowledge and assistance for other forensic investigators.
- || risperidone / Generic mfg., quetiapine / Generic mfg.
Clinical, Journal: Quetiapine augmentation of prolonged exposure therapy in veterans with PTSD and a history of mild traumatic brain injury: design and methodology of a pilot study. (Pubmed Central) - Mar 31, 2021
P1
We expect that the success of this ongoing study should provide us with the preliminary data necessary to design a full-scale randomized trial. Positive efficacy results in a full- scale trial should inform new VA guidelines for clinical practice by showing that quetiapine-related improvements in patient engagement and retention may be the most effective approach to assure that VA resources achieve the best possible outcome for veterans.
- || lithium carbonate ER / Generic mfg., risperidone / Generic mfg.
Clinical, Journal: Lithium vs valproate in the maintenance treatment of bipolar I disorder: A post- hoc analysis of a randomized double-blind placebo-controlled trial. (Pubmed Central) - Mar 30, 2021
However, study design and small sample size might have precluded from detecting an effect if true difference in efficacy existed. Further head-to-head investigations with stratified designs are needed to evaluate maintenance therapies.
- | risperidone / Generic mfg.
Journal: Expression of Dopamine D and Serotonin 5-HT Receptors in Blood Mononuclear Cells in Schizophrenia. (Pubmed Central) - Mar 30, 2021
Schizophrenia patients display a distinctive pattern of dopamine and serotonin receptor mRNA expression in blood mononuclear cells. This expression is little affected by antipsychotic treatment and it may therefore serve as a useful diagnostic biomarker for schizophrenia.
- || risperidone / Generic mfg.
Clinical, Journal: A Rare Case of Risperidone Induced Reticular Palmar Pigmentation. (Pubmed Central) - Mar 27, 2021
This expression is little affected by antipsychotic treatment and it may therefore serve as a useful diagnostic biomarker for schizophrenia. No abstract available
- | risperidone / Generic mfg., amisulpride / Generic mfg.
Journal: Transcriptional Effects of Psychoactive Drugs on Genes Involved in Neurogenesis. (Pubmed Central) - Mar 18, 2021
This can, at least in part, explain the mechanisms by which these drugs decrease neurogenesis at a transcriptional level in vitro. These results were supported by the finding of increased metabolite markers of mature neurons following treatment with most of the drugs tested, suggesting increased proportions of mature relative to immature neurons consistent with reduced neurogenesis.
- risperidone / Generic mfg.
[VIRTUAL] Atypical gait in a patient with Huntington’s disease (HD): Functional movement disorders in the spectrum of motor phenotypes in HD () - Mar 18, 2021 - Abstract #AAN2021AAN_1334;
It reflects the complex interaction between neuropsychiatric and motor symptoms in HD and highlights the importance of treating all the different manifestations of the disease. Early diagnosis and treatment of FMD can positively influence the patient’s quality of life.
- risperidone / Generic mfg.
[VIRTUAL] An Adult Case of Non-Ketotic Hyperglycinemia Due to Novel Compound Heterozygous Variants in GLDC () - Mar 18, 2021 - Abstract #AAN2021AAN_720;
NKH must be considered in patients presenting with acute-onset encephalopathy and movement disorder associated with abnormal amino acid profile. Rapid exome sequencing should be sent early to confirm the diagnosis expeditiously and assess for secondary findings.
- risperidone / Generic mfg.
[VIRTUAL] Beyond A Vascular Event: A Case Of Hyperglycemia Induced Hemi Balism/Hemichorea. () - Mar 18, 2021 - Abstract #AAN2021AAN_655;
Although this entity is a diagnosis of exclusion, entertaining the possibility of its occurrence while evaluating a patient in the acute setting is crucial. This will help minimize initial misdiagnosis as treatment modalities differ.
- Trileptal (oxcarbazepine) / Novartis
[VIRTUAL] Anti LGI1 Encephalitis–A Retrospective Analysis of Clinical Features and Treatment Response () - Mar 18, 2021 - Abstract #AAN2021AAN_299;
Anti LGI1 encephalitis has a classic phenotype with FBDS, encephalopathy, episodic memory disturbance, hyponatremia and MRI showing limbic encephalitis. Anti LGI 1 encephalitis responds very well to first line immunotherapy
- || risperidone / Generic mfg.
PK/PD data, Journal: Modelling Age-Related Changes in the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Different CYP2D6 Phenotypes Using a Physiologically Based Pharmacokinetic Approach. (Pubmed Central) - Mar 16, 2021
Metabolic ratio combined with PBPK modelling can provide a powerful tool to identify potential CYP2D6 PM during therapeutic drug monitoring. Based on genetic, anatomical and physiological changes during aging, PBPK models ultimately support decision-making regarding dose-optimization strategies to ensure the best therapy for each patient over the age of 65 years.
- || risperidone / Generic mfg., amisulpride / Generic mfg., ziprasidone / Generic mfg.
Clinical, Journal: Optimizing and Individualizing the Pharmacological Treatment of First-Episode Schizophrenic Patients: Study Protocol for a Multicenter Clinical Trial. (Pubmed Central) - Mar 16, 2021
P=N/A
In subproject 1, 1,800 first-episode patients with schizophrenia are randomized into six different antipsychotic monotherapy groups (olanzapine, risperidone, aripiprazole, ziprasidone, amisulpride, and haloperidol) for an 8-week treatment...In subproject 2, apart from verifying the prediction model established in subproject 1 based on an independent cohort of 1,800 first-episode patients with schizophrenia, we recruit patients from a verification cohort who did not get an effective response after an 8-week antipsychotic treatment into a randomized double-blind controlled trial with minocycline (200 mg per day) and sulforaphane (3 tables per day) to explore add-on treatment for patients with schizophrenia...In subproject 3, we tend to carry out one trial to construct an intervention strategy for metabolic syndrome induced by antipsychotic treatment and another one to build a prevention strategy for patients at a high risk of metabolic syndrome, which combines metformin and lifestyle intervention...Trial Registration: This trial has been registered on Clinicalrials.gov (NCT03451734). The protocol version is V.1.0 (April 23, 2017).
- risperidone / Generic mfg.
[VIRTUAL] An Atypical Precipitant for Life Threatening New Onset DKA () - Mar 14, 2021 - Abstract #ATS2021ATS_3709;
Risperidone can have serious complications, further encouraging clinicians to be mindful when prescribing this class of medication. Based on the absence of islet cell autoimmunity, the presence of hyperosmolarity, excess adiposity, hepatic steatosis, acanthosis nigricans and excellent response to insulin, we diagnosed ketosis prone type-2 diabetes in the setting of new onset DKA.
- | risperidone / Generic mfg., clozapine / Generic mfg.
Journal: Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells. (Pubmed Central) - Mar 12, 2021
Clozapine reduced the level of poly (I:C)-activated NLRP3 expression by 57%, which was higher than the reduction thay was seen with CRID3 treatment (45%). These results suggest that clozapine might exhibit anti-inflammatory effects by inhibiting NLRP3 inflammasome and this activity is not typical with the use of other antipsychotic drugs under the conditions of strong microglial activation.
- || risperidone / Generic mfg.
Clinical, Review, Journal: Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review. (Pubmed Central) - Mar 12, 2021
However, evidence was strongly affected by serious methodological drawbacks and lack of studies. Notably, reports on adult patients are underrepresented, mostly for ASD and ADHD.
- || risperidone / Generic mfg.
Clinical, Journal: Associations between individual antipsychotics and the risk of arrests and convictions of violent and other crime: a nationwide within-individual study of 74 925 persons. (Pubmed Central) - Mar 12, 2021
Notably, reports on adult patients are underrepresented, mostly for ASD and ADHD. There is heterogeneity in the associations between specific antipsychotics and subsequent arrests and convictions for any drug-related and violent crimes.
- | risperidone / Generic mfg.
Journal: Proteinoid Nanocapsules as Drug Delivery System for Improving Antipsychotic Activity of Risperidone. (Pubmed Central) - Mar 11, 2021
They were characterized in terms of diameter, size distribution, drug loading, and long-term storage. Behavioral studies on mice found enhanced antipsychotic activity compared to free RSP.
- || risperidone / Generic mfg.
Clinical, Journal, HEOR: Drug-dependent risk of self-harm in patients with bipolar disorder: a comparative effectiveness study using machine learning imputed outcomes. (Pubmed Central) - Mar 11, 2021
P=N/A
Behavioral studies on mice found enhanced antipsychotic activity compared to free RSP. Our data support the evidence on the effectiveness of antidepressants, MSAs, and psychotherapy for self-harm prevention in BD.
- | risperidone / Generic mfg.
Preclinical, Journal: The preclinical discovery and development of paliperidone for the treatment of schizophrenia. (Pubmed Central) - Mar 10, 2021
Its positive activity on neurogenesis, neuronal, and synaptic plasticity deserves to be emphasized. The clinical superiority of paliperidone is based primarily on the available formulations of the drug rather than in the subtle differences in its pharmacokinetic/pharmacodynamic properties compared to risperidone.
- || risperidone / Generic mfg.
Clinical, Journal: Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis. (Pubmed Central) - Mar 9, 2021
The clinical superiority of paliperidone is based primarily on the available formulations of the drug rather than in the subtle differences in its pharmacokinetic/pharmacodynamic properties compared to risperidone. These data suggest that several neurobiological alterations in the form of reduced functional connectivity and surface area and increased cortical thickness underpin the effect of prolonged DUP.
- || risperidone / Generic mfg., clozapine / Generic mfg.
Clinical, Journal: Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial. (Pubmed Central) - Mar 9, 2021
While these findings do not negate the potential of these drugs to reduce multiple sclerosis-associated neuroinflammation, they highlight the need for further research to understand the pharmacodynamic profile and effect of clozapine and risperidone in patients with pMS. ACTRN12616000178448.
- risperidone / Generic mfg., donepezil / Generic mfg.
[VIRTUAL] 9108 The Challenge of Clinical Pharmacology and Pharmacogenetics in Later Life () - Mar 8, 2021 - Abstract #APA2021APA_54;
The author has also worked for many years to reduce the prescription of antipsychotics to patients suffering from dementia accompanied by agitation. In the course of this talk the major drug metabolizing polymorphisms will be reviewed, emphasizing their potential for understanding drug-drug interactions and inter-individual pharmacokinetics.
- risperidone / Generic mfg.
[VIRTUAL] 9135 Refining Translational Medicine Efforts in Neurodevelopmental Disorders () - Mar 8, 2021 - Abstract #APA2021APA_53;
In FXS we are defining molecular and neurophysiologic variation across individuals in a way that allows for subgroup selection and treatment matching in ways previously not utilized in our field. We are hopeful that our ability to better parse variation even in single gene neurodevelopmental disorders will results in the personalization of medicine in this field leading to success in treatment development.
- Caplyta (lumateperone) - Intra / Cellular Therapies
[VIRTUAL] Sodium Nitroprusside Enhances the Antipsychotic-like Effect of Lumateperone and Clozapine in the Conditioned Avoidance Response Test () - Mar 7, 2021 - Abstract #CINP2021CINP_172;
Thus, the combination of lumateperone and SNP may improve efficacy in schizophrenic patients and, tentatively, also in TRS. Moreover, our current experimental data propose that SNP can also enhance the antipsychotic effect of clozapine, still the only FDA-approved drug for TRS.
- risperidone / Generic mfg., amisulpride / Generic mfg.
[VIRTUAL] Self-harm in Patients with Schizophrenia in Taiwan: Incidence, Risk Factors and Protective Effect of Antipsychotics () - Mar 7, 2021 - Abstract #CINP2021CINP_168;
Our study revealed that patients with schizophrenia had higher self-harm risk and more associated risk factors. The protective effect on self-harm may vary across different antipsychotics, and clozapine was associated with the lowest self-harm risk in patients with schizophrenia.
- Saphris (asenapine) / Lundbeck, Meiji Seika, AbbVie
[VIRTUAL] Efficacy and Tolerability of Antipsychotics in the Treatment of Children and Adolescents with Schizophrenia: A Systematic Review and Meta-Analysis () - Mar 7, 2021 - Abstract #CINP2021CINP_138;
Medications choice needs to be carefully evaluated to achieve optimal clinical benefit while minimizing burden of side effects for the patients. References: 1 Hollis C (2000) Adult outcomes of child- and adolescent-onset schizophrenia: diagnostic stability and predictive validity.
- risperidone / Generic mfg.
[VIRTUAL] Circadian Patterns of Hallucinatory Experiences in Patients with Schizophrenia: Potentials for Chrono-pharmacology () - Mar 7, 2021 - Abstract #CINP2021CINP_124;
Since the dopamine D2 receptor blockade by antipsychotics was very stable, the circadian rhythm that we found in this study seemed to be irrelevant to the treatment. These findings will lead to individualized antipsychotic dosing schedule according to the circadian rhythm of the positive symptoms in each individual patient with schizophrenia.
- risperidone / Generic mfg.
[VIRTUAL] Camptocormia Secondary to Dopamine-Antagonist-Induced Dystonia of the Rectus Abdominis Muscles: A Case Report () - Mar 7, 2021 - Abstract #CINP2021CINP_123;
This suggests that lowering the intensity of dopamine D2 receptor blockade of dopamine antagonist improved the dystonia of the rectus abdominis muscles and thereby camptocormia. Thus, in a case of camptocormia, abdominal physical examination and abdominal CT scan may be highly advisable considering the possibility of truncal dystonia.
- || risperidone / Generic mfg.
Review, Journal: Limiting antipsychotic drugs in dementia. (Pubmed Central) - Mar 6, 2021
Trials of deprescribing are therefore recommended Behaviours should be seen as symptoms that have an underlying cause. Treatment should target these causes, rather than the resultant behaviours.
- | risperidone / Generic mfg., olanzapine / Generic mfg.
Journal: Understanding Mechanisms Underlying Non-Alcoholic Fatty Liver Disease (NAFLD) in Mental Illness: Risperidone and Olanzapine Alter the Hepatic Proteomic Signature in Mice. (Pubmed Central) - Mar 5, 2021
Both AA drugs caused development of steatosis in comparison with vehicle controls (p < 0.01) and affected multiple pathways relating to energy metabolism, NAFLD, and immune function. AA-associated alteration in autonomic function appears to be a unifying theme in the regulation of hepatic pathology.
- || risperidone / Generic mfg.
Clinical: just like they tested risperdal on children. #gynecomastia (Twitter) - Mar 4, 2021
- || risperidone / Generic mfg.
Clinical, Journal: Investigation of Risperidone Treatment Associated With Enhanced Brain Activity in Patients Who Stutter. (Pubmed Central) - Mar 2, 2021
We propose that the mechanism of risperidone's action in stuttering, in part, involves increased metabolism of striatal astrocytes. We conclude that using neuroimaging techniques to visualize changes in the brain of those who stutter can provide valuable insights into the pathophysiology of the disorder and guide the development of future interventions.
- || risperidone / Generic mfg., amisulpride / Generic mfg., ziprasidone / Generic mfg.
Clinical, Observational data, Journal: Safety and related factors of treatment with long-term atypical antipsychotic in Chinese patients with schizophrenia: observational study. (Pubmed Central) - Mar 2, 2021
This is a large sample, non-interventional and long-term prospective clinical study designed to truly reflect the specific details of clinical practice, fully respect patients' needs, and understand patients' treatment intentions and actual treatment details. This research method details the aims, methods, study design, strengths and limitations of the study.
- risperidone / Generic mfg.
[VIRTUAL] Pharmacokinetics, Safety, and Tolerability of Ultra-Long Acting Sustained-Release Oral Risperidone in Patients with Schizophrenia or Schizoaffective Disorder () - Mar 1, 2021 - Abstract #SIRS2021SIRS_842;
P1, P1b
Both high and low doses of LYN-005 were well tolerated. Once weekly delivery of risperidone with this novel formulation has the potential to improve treatment adherence and quality of life of patients with schizophrenia or schizoaffective disorder.