levofloxacin / Generic mfg. 
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  • ||||||||||  Lamprene (clofazimine) / Novartis
    Review, Journal:  An overview of new antitubercular drugs, drug candidates, and their targets. (Pubmed Central) -  Jul 9, 2021   
    The last 10 years have made sudden progress giving some new and highly promising drugs including bedaquiline, delamanid, and pretomanid...These targets are either involved in cell wall biosynthesis, protein synthesis, DNA/RNA synthesis, or metabolism. This review discusses recent progress in the discovery of newly developed and Food and Drug Administration approved drugs as well as repurposed drugs, their targets, mode of action, drug-target interactions, and their structure-activity relationship.
  • ||||||||||  Cubicin (daptomycin) / Merck (MSD), Timcynis (ticarcillin and clavulanic acid) / Emcure Pharma
    Journal:  Drug-induced tolerance: the effects of antibiotic pre-exposure in Stenotrophomonas maltophilia. (Pubmed Central) -  Jul 9, 2021   
    In time-kill activity of levofloxacin, D25 presented a subpopulation of persisters with survival rate higher (1.6-fold) than the parental. Previous exposure of S. maltophilia to daptomycin can induce cross-tolerance to ceftazidime and ticarcillin-clavulanate and cross-persistence to levofloxacin.
  • ||||||||||  levofloxacin / Generic mfg.
    Trial completion date, Trial primary completion date, Surgery:  Levofloxacin Ocular Implant for Ocular Surgery (clinicaltrials.gov) -  Jul 8, 2021   
    P1,  N=5, Recruiting, 
    In conclusion, our results point towards carbohydrate-functionalized nanocarriers as a promising tool for improving TB treatment by targeted delivery of antibiotics. Trial completion date: Jun 2021 --> Dec 2021 | Trial primary completion date: Apr 2021 --> Sep 2021
  • ||||||||||  ceftriaxone / Generic mfg., rifampicin / Generic mfg., cefuroxime / Generic mfg.
    Clinical, Journal:  Properties of Mucoid Serotype 3 Streptococcus pneumoniae From Children in China. (Pubmed Central) -  Jul 7, 2021   
    All isolates were susceptible to penicillin, cefuroxime, ceftriaxone, meropenem, vancomycin, levofloxacin, trimethoprim/sulfamethoxazole, and rifampin but resistant to erythromycin...Antimicrobial susceptibility of ST180 and ST505 were compared, and the minimum inhibitory concentration (MIC) of ST505 isolates was significantly higher than that of ST180 for tetracycline, trimethoprim/sulfamethoxazole, and meropenem...It can cause noninvasive infection in children, and it has high susceptibility to a variety of antibiotics, especially β-lactams, but is resistant to macrolides. CC505 is the novel clonal complex found in China, which may be related to the worldwide mainstream clonal complex (CC180) but has its own biological characteristics.
  • ||||||||||  clarithromycin / Generic mfg., amoxicillin / Generic mfg.
    Retrospective data, Review, Journal:  The increasing antimicrobial resistance of Helicobacter pylori in Iran: A systematic review and meta-analysis. (Pubmed Central) -  Jul 4, 2021   
    In children, the resistance to furazolidone and a combination of clarithromycin and metronidazole is higher compared to adults. As a stable, high resistance to metronidazole was found in children and adults in all Iranian provinces, we suggest that metronidazole should not be included in the Iranian H pylori eradication scheme.
  • ||||||||||  Journal:  Prevalence, Antibiogram and Genetic Characterization of Listeria monocytogenes from Food Products in Egypt. (Pubmed Central) -  Jul 4, 2021   
    While, high resistance was observed against oxytetracycline (76.4%), trimethoprim-sulfamethoxazole (76.4%), chloramphenicol (70.5%), doxycycline (64.6%), levofloxacin (41.2%) and azithromycin (41.2%)...The partial 16S rRNA gene sequencing of three L. monocytogenes isolates showed a high nucleotide similarity (99.1-99.8%) between the study isolates and various global clones, and phylogenetic analysis clustered these L. monocytogenes strains with other Listeria species including L. welshimeri, L. seeligeri and L. innocua. This study demonstrates the impact of L. monocytogenes as a major contaminant of various food products and suggests more attention to the awareness and hygienic measures in the food industry.
  • ||||||||||  rifampicin / Generic mfg.
    Journal:  Saliva-based linezolid monitoring on a mobile UV spectrophotometer. (Pubmed Central) -  Jul 3, 2021   
    We validated a UV spectrophotometric assay using non-invasive saliva sampling for linezolid. The next step is to demonstrate clinical feasibility and value to facilitate programmatic implementation of TDM.
  • ||||||||||  levofloxacin / Generic mfg.
    [VIRTUAL] EVALUATION OF ANTIBIOTICOPROPHYLAXIS IN PROSTATIC BIOPSY AT HOSPITAL GERAL DE FORTALEZA () -  Jul 2, 2021 - Abstract #ICUC2021ICUC_288;    
    Urine culture performance before prostate biopsy appears to be an important factor for our reduced rate of infectious complications after transrectal prostate biopsy. A continuation of the project, with an increase in the sample of patients, is necessary for a more detailed comparative evaluation between these antibiotics.
  • ||||||||||  levofloxacin / Generic mfg.
    Journal:  Semi-Interpenetrated Hydrogels-Microfibers Electroactive Assemblies for Release and Real-Time Monitoring of Drugs. (Pubmed Central) -  Jul 2, 2021   
    After demonstrating its properties, the platform is loaded with levofloxacin and its release monitored externally by UV-vis spectroscopy and in situ by using the PHMeDOT network. In situ real-time electrochemical monitoring of the drug release from the engineered platform holds great promise for the development of multi-functional devices for advanced biomedical applications.
  • ||||||||||  levofloxacin / Generic mfg.
    Review, Journal:  Levofloxacin in veterinary medicine: a literature review. (Pubmed Central) -  Jul 2, 2021   
    Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.
  • ||||||||||  amoxicillin / Generic mfg.
    Journal:  Comparison of the bactericidal effects of quinolones against low-susceptible Haemophilus influenzae. (Pubmed Central) -  Jul 2, 2021   
    In addition, higher concentrations of tosufloxacin at 2×C and 4×C had bactericidal effects on not only susceptible but also low-susceptible strains. These data strongly suggest that we should consider the presence of low-susceptible strains and reconsider the appropriate dosage of tosufloxacin for treatment, especially for paediatric patients.
  • ||||||||||  Clinical, Journal:  Forgotten disease: an atypical case of Lemierre syndrome presenting as a soft tissue abscess. (Pubmed Central) -  Jul 1, 2021   
    A 29-year-old woman with sore throat, dyspnoea and left shoulder pain, who was on levofloxacin for 3 days, presented with worsening symptoms...She was started on clindamycin and ampicillin sulbactam for LS...Drainage of the left shoulder abscess grew Fusobacterium nucleatum After 2 weeks of a complicated intensive care unit stay, her haemodynamic status improved and she was transferred to the floor. LS has variable presentations, but regardless of the presentation, it is a potentially fatal disease-requiring prompt diagnosis and management.
  • ||||||||||  ceftriaxone / Generic mfg., ampicillin / Generic mfg., cefuroxime / Generic mfg.
    Clinical, Journal:  Antimicrobial defined daily dose in neonatal population. (Pubmed Central) -  Jun 30, 2021   
    A useful method for antimicrobial DDD measurement in neonatology has been designed to monitor antimicrobial consumption in hospital settings. It should be validated in further studies and thereby included in the design for neonatal antimicrobial stewardship programs in the future.