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0 Diseases |  |
137 Trials |
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137 Trials |  |
5343 News |  |
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- || Zemdri (plazomicin) / Ionis, Achaogen
Clinical, Journal: Comparative activity of plazomicin against extended-spectrum cephalosporin-resistant Escherichia coli clinical isolates (2012-2017) in relation to phylogenetic background, sequence type 131 subclones, bla genotype, and resistance to comparator agents. (Pubmed Central) - Dec 29, 2021
For most study agents, antimicrobial activity against ESCREC varied extensively in relation to multiple bacterial characteristics, including clonal background, whereas for plazomicin, it varied only by ST131 subclone (C1-M27 isolates least susceptible, O16 isolates most susceptible). These findings support plazomicin as a reliable alternative for treating ESCREC infections and urge continued attention to the C1-M27 ST131 subclone.
- || Clinical, PK/PD data, Journal: Pharmacokinetic/pharmacodynamic evaluation of the antimicrobial therapy of pneumococcal invasive disease in adults in post-PCV13 vaccine period in Madrid, Spain. (Pubmed Central) - Dec 29, 2021
For meningitis, 2 g q6h ensures probabilities of target attainment ≥90% for MIC up to 1 mg/L. Our study confirms that after the implementation of PCV13 vaccine, the treatment with benzylpenicillin and cefotaxime provides high probability of the therapy success of IPD, including meningitis.
- || levofloxacin / Generic mfg., cisplatin / Generic mfg.
Clinical, Journal: Levofloxacin might be safe to use for OSCC patients. (Pubmed Central) - Dec 29, 2021
The combination has shown less toxicity for healthy cells than single cisplatin treatment. Therefore, our apoptotic findings suggest that the different dosage combinations are necessary to understand the interaction for the treatment of tongue squamous cell carcinoma.
- | levofloxacin / Generic mfg.
Journal: Cadaverine biosynthesis contributes to decreased Escherichia coli susceptibility to antibiotics. (Pubmed Central) - Dec 29, 2021
The same correlation in a special group of low-level resistant clinical E. coli isolates was revealed. So, cadaverine biosynthesis appeared to be a significant player in decreased E. coli antibiotic susceptibility development.
- | amoxicillin / Generic mfg.
Journal: Diagnostic performance of the culture and susceptibility of Helicobacter pylori in peruvian patients: results from a sentinel laboratory. (Pubmed Central) - Dec 29, 2021
Furthermore, H. pylori multiple resistance presents high frequencies in infected patients. The broth microdilution method could be implemented in different hospitals in Peru as a surveillance tool for H. pylori antimicrobial resistance.
- | levofloxacin / Generic mfg., moxifloxacin intravenous / Generic mfg.
Retrospective data, Journal: Distinguishing Relapse From Reinfection With Whole-Genome Sequencing in Recurrent Pulmonary Tuberculosis: A Retrospective Cohort Study in Beijing, China. (Pubmed Central) - Dec 28, 2021
MTB isolates were more prone to develop levofloxacin resistance than moxifloxacin resistance after FQ exposure. The patients at high-risk for relapses deserve more careful investigation.
- | rifampicin / Generic mfg.
Journal: Microbial Distribution and Antibiotic Susceptibility of Bloodstream Infections in Different Intensive Care Units. (Pubmed Central) - Dec 28, 2021
The current study demonstrated the distribution of prevalent microorganisms, and their antimicrobial susceptibility exhibited a high divergence among BSIs in different ICUs from a tertiary hospital and an outer suburban hospital in Beijing. Therefore, different antibiotic therapies for various wards and distinct age groups (especially between pediatric and elderly patients) should be considered to control the emergence and spread of highly antibiotic-resistant infections.
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
Journal: Assessment of the effectiveness of early treatment in SARS-CoV-2 infection (Pubmed Central) - Dec 28, 2021
The use of the assessed drugs should take into account the time of onset of SARS-CoV-2 infection and the severity of the disease course, including comorbidities. The presented analysis of the effectiveness of early treatment in patients infected with SARS-CoV-2 requires further clinical trials.
- | ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg.
Retrospective data, Journal: Levofloxacin Versus Ciprofloxacin-Based Prophylaxis during the Pre-Engraftment Phase in Allogeneic Hematopoietic Stem Cell Transplant Pediatric Recipients: A Single-Center Retrospective Matched Analysis. (Pubmed Central) - Dec 27, 2021
The median of Gram-negative infection-related antibiotics was 10 days in the levofloxacin group compared with 20 days in the ciprofloxacin group (p < 0.0001). The number of days with body temperature ≥38 °C was significantly less in the levofloxacin group (p < 0.001).
- | levofloxacin / Generic mfg.
Journal: Formulation and Evaluation of Topical Biodegradable Films Loaded with Levofloxacin Lipid Nanocarriers. (Pubmed Central) - Dec 27, 2021
Further clinical studies are strongly recommended. Graphical Abstract.
- | Journal: Evaluation of different antigenic preparations against necrotic enteritis in broiler birds using a novel Clostridium perfringens type G strain. (Pubmed Central) - Dec 25, 2021
The additional TpeL toxin in C. perfringens type G has been proved to be an additional key biological factor in the pathogenesis of NE in broiler chickens. Considering the release of more immunogenic proteins, the SS proved to be a better immunogenic preparation against NE with a multiple immunization dose.
- || clarithromycin / Generic mfg., amoxicillin / Generic mfg.
Clinical, Journal: Genotyping Helicobacter pylori antibiotic resistance - and virulence-associated genes in patients with gastric cancer in Wenzhou, China. (Pubmed Central) - Dec 25, 2021
The frequency of gene mutations associated with metronidazole, levofloxacin, and clarithromycin resistances was high and that associated with amoxicillin resistance was relatively low. The mutation patterns were diverse, and the rates of multiple gene mutations were high.
- | Retrospective data, Journal: Antibiotic-resistant profile and the factors affecting the intravenous antibiotic treatment course of generalized Staphylococcal Scalded Skin Syndrome: a retrospective study. (Pubmed Central) - Dec 25, 2021
Oxacillin and vancomycin resistance was rare and clindamycin resistance was common. Clindamycin monotherapy for SSSS should be avoided.
- || Maxidex (dexamethasone eye drops, suspension) / Novartis
Clinical, Review, Journal: A One-Week Course of Levofloxacin/Dexamethasone Eye Drops: A Review on a New Approach in Managing Patients After Cataract Surgery. (Pubmed Central) - Dec 24, 2021
In addition, this study underlines that a follow-up visit after 1 week allows for a decision about whether to stop or continue a treatment in patients still experiencing symptoms or inflammation. In conclusion, this new dose combination could represent a turning point in managing patients after cataract surgery, while mostly avoiding antibiotic resistance and improving treatment adherence.
- || ampicillin / Generic mfg.
Clinical, Journal: Prevalence and Risk Factors of Group B Streptococcus Colonization in Pregnant Women: A Pilot Study in Palestine. (Pubmed Central) - Dec 24, 2021
Further research is needed to determine the GBS serotypes common in West Bank and the burden they cause on the health system. Moreover, this study also highlights the need to establish a screening program suited to a developing country with low control on the antibiotic's prescription protocols.
- || clarithromycin / Generic mfg., amoxicillin / Generic mfg.
Clinical, Journal: Fourteen-day sequential therapy is superior to 7-day triple therapy as first-line regimen for Helicobacter pylori infected children. (Pubmed Central) - Dec 23, 2021
Moreover, this study also highlights the need to establish a screening program suited to a developing country with low control on the antibiotic's prescription protocols. In treatment-naïve children with H. pylori infection, 14-day sequential therapy is superior to triple therapy, and achieve a high eradication rate (above 90%) in an area of high clarithromycin resistance.
- || piperacillin sodium/tazobactam sodium / Generic mfg., vancomycin / Generic mfg., levofloxacin / Generic mfg.
Clinical, Licensing / partnership, Journal: Implementation of telehealth antimicrobial stewardship through partnership of an academic medical center and a community hospital. (Pubmed Central) - Dec 23, 2021
The partnership between an academic medical center and a small community hospital improved antimicrobial utilization and clinical outcomes. Successful telehealth antimicrobial stewardship models should be explored further as a means to provide optimal patient care.
- | Gatiflox (gatifloxacin) / Orient Europharma
Journal: Fluoroquinolones Suppress TGF-β and PMA-Induced MMP-9 Production in Cancer Cells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment. (Pubmed Central) - Dec 23, 2021
Successful telehealth antimicrobial stewardship models should be explored further as a means to provide optimal patient care. Overall, we demonstrated that FQs inhibit cancer cell migration and invasion by downregulating MMP-9 expression and revealed the cellular mechanisms underlying their potential value in cancer treatment.
- || Clinical, Journal: Physical compatibility of Normosol-R with critical care medications used in patients with COVID-19 during simulated Y-site administration. (Pubmed Central) - Dec 22, 2021
Overall, we demonstrated that FQs inhibit cancer cell migration and invasion by downregulating MMP-9 expression and revealed the cellular mechanisms underlying their potential value in cancer treatment. Normosol-R is compatible for Y-site administration with all tested medications except for pantoprazole, phenylephrine, and highly concentrated norepinephrine, allowing for potential increased use in patients with COVID-19.
- | Phase classification, Enrollment change, Trial completion date, Trial primary completion date: REMAP-CAP: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (clinicaltrials.gov) - Dec 21, 2021
P3, N=10000, Recruiting, Sponsor: UMC Utrecht
Normosol-R is compatible for Y-site administration with all tested medications except for pantoprazole, phenylephrine, and highly concentrated norepinephrine, allowing for potential increased use in patients with COVID-19. Phase classification: P4 --> P3 | N=7100 --> 10000 | Trial completion date: Dec 2023 --> Dec 2025 | Trial primary completion date: Dec 2021 --> Dec 2023
- ||| Lamprene (clofazimine) / Novartis, Sirturo (bedaquiline) / J&J, Pharmstandard
Clinical, Journal, Adverse events: Analysis of the side effect of QTc interval prolongation in the bedaquiline regimen in drug resistant tuberculosis patients. (Pubmed Central) - Dec 21, 2021
Phase classification: P4 --> P3 | N=7100 --> 10000 | Trial completion date: Dec 2023 --> Dec 2025 | Trial primary completion date: Dec 2021 --> Dec 2023 This study can be concluded that there were no differences in the QTc prolongation between the groups of BDQ regimen (BDQ, BDQ + LFX, BDQ + CFZ and BDQ + LFX + CFZ) and the groups of risk factors.
- || ceftriaxone / Generic mfg., ampicillin / Generic mfg., amoxicillin / Generic mfg.
Clinical, Journal: Antimicrobial Resistance in Salmonella Typhi Isolated From a Referral Hospital of Kathmandu, Nepal. (Pubmed Central) - Dec 20, 2021
The antibiotic susceptibility testing for 11 different antibiotics (nalidixic acid, ciprofloxacin, ofloxacin, levofloxacin, cefixime, ceftriaxone, cefotaxime, azithromycin, cotrimoxazole, chloramphenicol, and amoxicillin) was performed by disk diffusion method...It was revealed that 97.8% S. Typhi isolates were susceptible to conventional first-line antibiotics (ampicillin, chloramphenicol, and cotrimoxazole), 97.3% to cephalosporins and 95.7% to azithromycin...The trends of increasing azithromycin MIC value among S. Typhi might limit its use for the treatment of typhoid fever. Effectiveness of conventional first-line antibiotics in vitro suggests considering their clinical use after large-scale studies.
- | levofloxacin / Generic mfg.
Journal: HigB1 Toxin in Mycobacterium tuberculosis Is Upregulated During Stress and Required to Establish Infection in Guinea Pigs. (Pubmed Central) - Dec 20, 2021
qPCR studies revealed that higBA1 is upregulated in nutrient limiting conditions and upon exposure to levofloxacin...Transcriptome analysis suggested that deletion of higB1 reduced the expression of genes involved in virulence, detoxification and adaptation. The present study describes the role of higB1 toxin in M. tuberculosis physiology and highlights the importance of higBA1 locus during infection in host tissues.
- | levofloxacin / Generic mfg., tetracycline / Generic mfg.
Journal: Bismuth oxybromide/bismuth oxyiodide nanojunctions decorated on flexible carbon fiber cloth as easily recyclable photocatalyst for removing various pollutants from wastewater. (Pubmed Central) - Dec 18, 2021
Besides, CFC/BiOBr/BiOI can efficiently reduce 93.5% chemical oxygen demand (COD) concentration of acrylic resin production wastewater (ARPW) under visible-light illumination for 3 h, better than CFC/BiOBr (36.6% COD). Therefore, CFC/BiOBr/BiOI has broad application prospects in purifying wastewater as a new type of easily recycled photocatalyst.
- || levofloxacin / Generic mfg.
I can assume that previous treatment with levofloxacin for UTI might select resistance for that and maybe ESBL @OncIDPharmd @ClancyNeil ? But I do not how the frequency and the duration which one affect most. A recent community PNA treated for 3 days with amoxi +/- doxy who cares (Twitter) - Dec 17, 2021
- || ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg., meropenem / Generic mfg.
Clinical, Journal: Emergence of Clinical Pseudomonas aeruginosa Isolate Guangzhou-PaeC79 Carrying crpP, bla, and bla in Guangzhou of China. (Pubmed Central) - Dec 17, 2021
It contains one chromosomal DNA and one plasmid, with seven acquired antimicrobial resistance genes identified on the chromosome, including carbapenem resistance gene bla and fluoroquinolone resistance gene crpP, and carbapenem resistance gene bla located on an IncP-6-type plasmid pPAEC79 carrying a Tn3-like element. Carriage of any two of the resistance genes has never been previously reported, and simultaneous carriage of three bla and crpP may explain the bacterial phenotype as high-level resistance to imipenem and meropenem (≥16 μg/mL) and resistance to ciprofloxacin and levofloxacin.
- || rifampicin / Generic mfg.
Clinical, Journal: Methicillin-resistant Staphylococcus aureus of the clonal lineage ST5-SCCmecII-t2460 was associated with high mortality in a Wuhan hospital. (Pubmed Central) - Dec 17, 2021
In this study, SMRSA was associated with serious infections and poor prognosis. Compared with ST239, ST59, or other nSMRSA strains, patients infected with SMRSA strains have higher 30-day mortality, increased levels of inflammatory biomarkers, and more frequent ICU hospitalization and invasive procedures.
- | xevinapant (AT-406) / Ascenta, Merck (MSD)
Journal: Nanoparticles encapsulation of Phoenix dactylifera (date palm) mucilage for colonic drug delivery. (Pubmed Central) - Dec 17, 2021
A controlled release of drug levofloxacin hemihydrate was evaluated using crude/ nano formulated mucilage as excipient. Nano formulated mucilage delayed the onset exposure of drug in gastric medium giving recommendations as value added bio binder for drug to the target organ.
- | levofloxacin / Generic mfg., moxifloxacin intravenous / Generic mfg.
Journal: Fluoroquinolone Resistance Among Isolates of Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan. (Pubmed Central) - Dec 16, 2021
FQ resistance needs to be continuously monitored to avoid further side effects. This study provides useful information for better management of FQ resistance with reference to the global TB control program 2030.
- || levofloxacin / Generic mfg., azithromycin / Generic mfg.
Clinical, Journal: The treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. (Pubmed Central) - Dec 16, 2021
Levofloxacin proved to be an effective and safe drug in the treatment of children with macrolide-resistant mycoplasma pneumonia. This study will provide a reference for evaluating the efficacy and safety of levofloxacin in the paediatric population.
- | rifampicin / Generic mfg.
Biomarker, Journal, Next-generation sequencing: Targeted next generation sequencing directly from sputum for comprehensive genetic information on drug resistant Mycobacterium tuberculosis. (Pubmed Central) - Dec 16, 2021
tNGS can rapidly identify tuberculosis, lineage, and drug resistance with faster turnaround than phenotypic testing. tNGS is a potential alternative to phenotypic testing in high-burden settings.
- ||| levofloxacin / Generic mfg., moxifloxacin intravenous / Generic mfg.
Clinical, Clinical guideline, Journal: Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Quinolones. (Pubmed Central) - Dec 16, 2021
Cross-reactivity among quinolones is controversial among different studies, with the lowest cross-reactivity for levofloxacin. Desensitization may be considered in allergy to quinolones when no other alternative exist.
- || clarithromycin / Generic mfg.
Clinical, Journal: Prevalence of Helicobacter pylori Antimicrobial Resistance Among Patients Recruited in Endoscopy Units in Santiago, Chile. (Pubmed Central) - Dec 16, 2021
The prevalence of ClaR and LevoR is high in Santiago, according to International guidelines that recommend avoiding schemes with antibiotic resistance >15%. Our findings provide evidence to re-evaluate current therapies and guide empirical first- and second-line eradication treatments in Chile.
- | levofloxacin / Generic mfg., moxifloxacin intravenous / Generic mfg.
Journal: Association between fluoroquinolone resistance and MRSA genotype in Alexandria, Egypt. (Pubmed Central) - Dec 16, 2021
Moxifloxacin resistance was high, most resistant isolates belonged to t037 and SCCmec III, suggesting local dissemination and antibiotic pressure. We recommend caution in treating MRSA infections with moxifloxacin.
- || clarithromycin / Generic mfg., rifampicin / Generic mfg., amoxicillin / Generic mfg.
Clinical, Journal: Detection of Helicobacter pylori by invasive tests in adult dyspeptic patients and antibacterial resistance to six antibiotics, including rifampicin in Turkey. Is clarithromycin resistance rate decreasing? (Pubmed Central) - Dec 16, 2021
The high levels of resistance to metronidazole and levofloxacin limit the empirical use of these antibiotics in the eradication protocol. Owing to the low level of resistance determined for rifampicin, this antibiotic could be included in the eradication protocol, in the event of the need for rescue therapy in Turkey.
- | ampicillin / Generic mfg.
Journal: EHEC O111:H8 strain and norovirus GII.4 Sydney [P16] causing an outbreak in a daycare center, Brazil, 2019. (Pubmed Central) - Dec 16, 2021
In this outbreak, it was possible to identify an uncommon stx2a + EHEC O111:H8 strain, and the most recent pandemic norovirus strain GII.4 Sydney [P16]. Our findings reinforce the need for surveillance and diagnosis of multiple enteric pathogens by public health authorities, especially during outbreaks.
- || vancomycin / Generic mfg., levofloxacin / Generic mfg.
Clinical, Review, Journal: Late onset periprosthetic joint infection of the knee caused by Streptococcus anginosus. Case presentation and literature review. (Pubmed Central) - Dec 16, 2021
anginosus has been anecdotical related to implant devices infections such as vascular prosthesis or orthopedic implants, however, PJI of the knee has never been fully reported before. We describe the case of a late onset periprosthetic knee infection due to Streptococcus anginosus successfully treated by a two-stage revision arthroplasty and postoperative parenteral Vancomycin, (2 g per day) and Levofloxacin (750 mg per day) for 4 weeks and then oral Levofloxacin for a further 2 weeks.
- | clarithromycin / Generic mfg., amoxicillin / Generic mfg.
Journal: Effectiveness of antibacterial agents against cell-invading bacteria such as Streptococcus pyogenes and Haemophilus influenzae. (Pubmed Central) - Dec 16, 2021
We describe the case of a late onset periprosthetic knee infection due to Streptococcus anginosus successfully treated by a two-stage revision arthroplasty and postoperative parenteral Vancomycin, (2 g per day) and Levofloxacin (750 mg per day) for 4 weeks and then oral Levofloxacin for a further 2 weeks. GRNX was the most effective agent against bacteria invading cells.
- | levofloxacin / Generic mfg.
Journal: Determination of levofloxacin by HPLC with fluorescence detection in human breast milk. (Pubmed Central) - Dec 16, 2021
Mean absolute recovery was 96.18%. The developed method has been successfully applied to the determination of levofloxacin in human breast milk taken from two healthy volunteers.
- | levofloxacin / Generic mfg.
Journal: Optimization of a ligand exchange chromatography method for the enantioselective separation of levofloxacin and its chiral impurity. (Pubmed Central) - Dec 16, 2021
The developed method has been successfully applied to the determination of levofloxacin in human breast milk taken from two healthy volunteers. The following method is accurate and robust to quantify and characterize the presence of levofloxacin impurity in raw material for pharmaceutical compounds.
- || levofloxacin / Generic mfg.
Clinical, PK/PD data, Journal: Population Pharmacokinetics of Oral Levofloxacin in Healthy Volunteers and Dosing Optimization for Multidrug-resistant Tuberculosis Therapy. (Pubmed Central) - Dec 16, 2021
A higher dose of levofloxacin might be needed to treat tuberculosis. However, further studies on the efficacy and safety of this dose are needed to confirm our findings.
- || ampicillin / Generic mfg., cefuroxime / Generic mfg.
Clinical, Journal: Characterization of a bacterial strain Lactobacillus paracasei LP10266 recovered from an endocarditis patient in Shandong, China. (Pubmed Central) - Dec 16, 2021
Our results based on various types of assays consistently revealed that L. paracasei LP10266 was a potential pathogen to patients with a history of cardiac disease and inguinal hernia repair. Strain LP10266 showed strong biofilm formation ability and adherence, enhancing the awareness of L. paracasei infections.
- | Gatiflox (gatifloxacin) / Orient Europharma
Journal: Whole-genome analysis of drug-resistant Mycobacterium tuberculosis reveals novel mutations associated with fluoroquinolone resistance. (Pubmed Central) - Dec 16, 2021
Strain LP10266 showed strong biofilm formation ability and adherence, enhancing the awareness of L. paracasei infections. Our study reported possible additional mutations associated with FQ resistance in Mtb.
- | Journal: A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders. (Pubmed Central) - Dec 16, 2021
Corticosteroids were associated with about 7% of tendon related reports. The results augment the existing data on FQs safety concerns, specifically their potential effect on the musculoskeletal system.
- | levofloxacin / Generic mfg.
Journal: New chemiluminescent method of levofloxacin and ofloxacin determination based on terbium (III)-sensitized fluoroquinolone- KBrO reaction. (Pubmed Central) - Dec 16, 2021
The chemiluminescence intensity was correlated linearly (r = 0.9994) with the concentration of ofloxacin (or levofloxacin) in the range 1x10 -4x10 molL ; the detection limit was 3 x 10 molL for both fluoroquinolones. In the optimized conditions, the chemiluminescence of the systems of levofloxacin (or ofloxacin)-Tb (III)-KBrO -H SO was used for determination of these compounds in a mixture of fluoroquinolones and in pharmaceuticals.
- | levofloxacin / Generic mfg.
Journal: Three porous shapeable three-component hydrogen-bonded covalent-organic aerogels as backfill materials in a simulated permeable reactive barrier (PRB) for trapping levofloxacin. (Pubmed Central) - Dec 16, 2021
Furthermore, a laboratory PRB column packed with processable HOA-2 was set up to investigate the LEV removal, and the breakthrough data was explained by Adams-Bohart, Thomas, BDST and Yoon-Nelson models. We believe could hopefully bring HOAs into the real in-situ remediation of such challenging and persistent LEV-polluted groundwater with further massive-scale efficiently.
- | levofloxacin / Generic mfg.
Journal: Effective removal of levofloxacin drug and Cr(VI) from water by a composed nanobiosorbent of vanadium pentoxide@chitosan@MOFs. (Pubmed Central) - Dec 16, 2021
Adsorption of Cr(VI) was confirmed to be spontaneous and endothermic reactions, while LEVO was found to proceed via spontaneous and exothermic based on the thermodynamic parameters. The emerged VO@Ch/Cu-TMA is regarded as an excellent nanobiosorbent for removal of inorganic contaminant as Cr(VI) from all natural water samples (tap, sea and wastewater) with percentages range 92.43%-96.95% and organic contaminant as LEVO drug from tap and wastewater (91.99%-97.20%).
- | ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg., norfloxacin / Generic mfg.
Journal: Toxicity of fluoroquinolones on the cladoceran Daphnia magna. (Pubmed Central) - Dec 16, 2021
The risks were low and moderate in water samples from rivers and lakes, although concentrations of ciprofloxacin, norfloxacin and ofloxacin reported in some countries can cause toxicological damage to D. magna. In addition, urban wastewater and hospital wastewater samples constitute a threat to D. magna (high and moderate risks), requiring the treatment of these wastewater.
- || rifampicin / Generic mfg.
Clinical, Journal: Anti-tuberculosis drug-induced acute liver failure requiring transplantation in the second trimester of pregnancy: a case report. (Pubmed Central) - Dec 16, 2021
Further research is still needed to identify the risks of TB treatment and liver transplantation in pregnant women. A multidisciplinary team coordinated properly to optimize patient outcomes.
- || clarithromycin / Generic mfg., amoxicillin / Generic mfg.
Clinical, Journal: Minimum inhibitory concentrations of commonly used antibiotics against Helicobacter Pylori: A multicenter study in South China. (Pubmed Central) - Dec 16, 2021
pylori activity in vitro in South China. When different breakpoints were used, similar results were found with CLA, and LEV, but not with AMX, MTZ, or TET.