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137 Trials |
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137 Trials |  |
5343 News |  |
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- | Journal: Antimicrobial susceptibility of Trueperella pyogenes isolated from cattle and pigs with septicemia in southern Kyushu, Japan. (Pubmed Central) - Feb 12, 2023
However, 53.3% of the strains were resistant to tetracycline, 49.7% to streptomycin, 13.8% to erythromycin, 13.2% to clindamycin, and 1.2% to oxacillin and kanamycin...The present results provide new data on the range of the minimum inhibitory concentration (MIC) values of various antimicrobial agents for T. pyogenes isolated from livestock with septicemia. The breakpoint values used in this study are generally considered applicable.
- | Journal: Distribution and Drug Resistance of Pathogens in Oral Mucositis Associated with Chemotherapy in Patients with Malignant Hematopathy (Pubmed Central) - Feb 12, 2023
It is sensitive to glycopeptide antibiotics and aminoglycosides antibiotics. Poor oral hygiene, diabetes and sleep duration less than 8 hours per night are risk factors for oral mucositis with oral ulcer (severe).
- | Journal: Isolation and Identification of Coliform Bacteria and Multidrug-Resistant Escherichia coli from Water Intended for Drug Compounding in Community Pharmacies in Jordan. (Pubmed Central) - Feb 12, 2023
The susceptibility of the isolates to ceftazidime, doxycycline, tetracycline, azithromycin and amoxicillin/clavulanic acid were 92%, 61%, 46%, 23% and 15%, respectively...These findings expose an alarming situation that needs special attention by the acting pharmacists and competent authorities. Higher levels of personal hygiene in the pharmacies coupled with regular inspection of water quality may reduce the risk of microbial contamination in compounded products, especially multidrug-resistant strains of E. coli and other index microorganisms.
- | Observational data, Journal: Antibiotic Resistance of Helicobacter pylori and Related Risk Factors in Yangzhou, China: A Cross-Sectional Study. (Pubmed Central) - Feb 12, 2023
Higher levels of personal hygiene in the pharmacies coupled with regular inspection of water quality may reduce the risk of microbial contamination in compounded products, especially multidrug-resistant strains of E. coli and other index microorganisms. The resistance rates of H. pylori to clarithromycin, levofloxacin and metronidazole were very high in Yangzhou, China, various factors were related to bacterial resistance, and grasping these influencing factors can guide treatment.
- || levofloxacin / Generic mfg.
Clinical, Journal: Effect of Hypochlorous Acid on Blepharitis through Ultrasonic Atomization: A Randomized Clinical Trial. (Pubmed Central) - Feb 12, 2023
The resistance rates of H. pylori to clarithromycin, levofloxacin and metronidazole were very high in Yangzhou, China, various factors were related to bacterial resistance, and grasping these influencing factors can guide treatment. Topical 0.01% HOCL through ultrasonic atomization is a tolerable and effective eyelid hygiene treatment for blepharitis.
- OUTCOMES OF OUTPATIENT AUTO-HSCT (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1538;
Outpatient auto-HSCT is a safe and accessible alternative with significant benefits for patients. Despite the small size of our series, a lower rate of digestive complications, especially mucositis, and fewer febrile events are confirmed.
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
EFFICACY COMPARISON OF LEVOFLOXACIN AND RIFAXIMIN PROPHYLAXIS IN PATIENTS UNDERGOING ALLOGENEIC STEM CELL TRANSPLANTATION (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1495;
In another study, similar mortality, fever, rehospitalization for infection , and infections were observed with cefpodoxime and levofloxacin prophylaxis.In our study levofloxacin was found to be superior to rifaximin prophylaxis with less conversion to broad-spectrum antibiotics. Levofloxacin caused lower rate fever in AML patients.
- Mozobil (plerixafor) / Sanofi
IMPACT OF FLUOROQUINOLONE (FQP) PROPHYLAXIS ON INFECTIONS INCIDENCE IN AUTOLOGOUS STEM CELL TRANSPLANTATION (AUTO-HSCT) FOR MULTIPLE MYELOMA. A SINGLE CENTER EXPERIENCE (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1484;
The administration of FQP is an effective strategy of infection prophylaxis in the autologous setting, especially when the procedure is carried out in an outpatient regimen. A larger, prospective study would provide more conclusive findings on this controversial issue.
- GRAM NEGATIVE BLOODSTREAM INFECTION IN AUTOLOGOUS STEM CELL TRANSPLANTATION: A COMPARATIVE STUDY BETWEEN AT HOME AND HOSPITAL CARE MODEL (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1452;
The bacterial strains isolated at blood in both regimens of care after ASCT were full susceptible to the recommended antibiotics for febrile neutropenia. The absence of FQ in admitted patients did not worsen the overall survival.
- MANAGEMENT OF ADULT PATIENTS UNDERGOING AUTOLOGOUS STEM CELL TRANSPLANTATION IN AN OUT-PATIENT SETTING, THE EXPERIENCE OF THE VENEZUELAN PUBLIC TRANSPLANT CENTER (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1127;
out of the 13 ASCT performed in adults, 6 met the inclusion criteria; 2 with a diagnosis of non-hodgkin lymphoma and received a conditioning regimen with BCNU, ARA-C, etoposide, and melphalan (beam), the rest with a diagnosis of multiple myeloma that received high doses of Melphalan, all patients attended daily to the hospital to receive mobilization drug, conditioning regimen, only three patients stayed in the hospital the night after finishing the high doses of melphalan but were discharged the next morning, all received oral acyclovir and levofloxacin as prophylaxis after the infusion of stem cells, all of which were refrigerated. This strategy has proven to be effective, safe, and affordable for patients and it will continue to be implemented by our center.
- Darzalex (daratumumab) / J&J, Mozobil (plerixafor) / Sanofi
STEM CELL MOBILIZATION AND AUTOLOGOUS TRANSPLANT FOR IMMUNOGLOBULIN LIGHT CHAIN AMYLOIDOSIS IN A PATIENT DIALYSIS-DEPENDENT (ePoster Area) - Feb 11, 2023 - Abstract #EBMT2023EBMT_1121;
The combination of G-CSF together with plerixafor may be safe and effective in patients with ALA dependent on dialysis, as well as the use of adjusted melphalan. Further studies are needed to establish mobilization and HSCT regimens in dialysis patients that standardize procedures.
- | Observational data, Journal: Microbiological and clinical characteristics of Streptococcus pneumoniae serotype 3 infection and risk factors for severe outcome: A multicenter observational study. (Pubmed Central) - Feb 11, 2023
Although the incidence rates decreased during the COVID-19 pandemic, serotype 3 remained as an important cause of infection after the implementation of PCV13. Developing a more effective vaccine against serotype 3 and monitoring the antimicrobial-resistant sequence types are necessary.
- | Journal: Molecular Characterization and Epidemiology of Carbapenem-Resistant Enterobacteriaceae Isolated from Pediatric Patients in Guangzhou, Southern China. (Pubmed Central) - Feb 10, 2023
This study revealed bla was the most dominant carbapenemase gene in children in Guangzhou. Infection control measures need to be taken for the prevention and treatment of CRE infections.
- | levofloxacin / Generic mfg.
Journal: Carbodiimide crosslinked decellularized lenticules as a drug carrier for sustained antibacterial eye treatments. (Pubmed Central) - Feb 9, 2023
Infection control measures need to be taken for the prevention and treatment of CRE infections. The EDC/NHS CDLs (diameter: 6.36
- | Journal: Phenotypical Detection of β-Lactamases in a Multidrug-Resistant and Extensively Drug-Resistant Chryseobacterium indologens: A Rare Human Pathogen With Special References to Risk Factor. (Pubmed Central) - Feb 7, 2023
Although it is rarely encountered in the laboratory, it showed a remarkable effect in patients with underlying predisposing factors and prolonged hospital stays. The presence of betalactamases determined the drug-resistant activity on a wide spectrum of tested antibiotics.
- | Journal: Antimicrobial resistance profile of methicillin-resistant Staphylococcus aureus isolates in children reported from the ISPED surveillance of bacterial resistance, 2016-2021. (Pubmed Central) - Feb 7, 2023
The antibiotic-resistance rates varied among MRSA isolated from different sources. Because of the high antibiotic resistance rate to clindamycin, this antibiotic is not recommended for empirical treatment of MRSA infections, especially in osteomyelitis.
- | Zerbaxa (ceftolozane /tazobactam) / Merck (MSD)
Preclinical, Journal: In vitro activity of ceftolozane/tazobactam against Pseudomonas aeruginosa collected in the Study for Monitoring Antimicrobial Resistance Trends (SMART) between 2016-2019 in China. (Pubmed Central) - Feb 5, 2023
Compared with comparator antimicrobial agents, ceftolozane/tazobactam was more active than tested β-lactams, while being slightly less active than amikacin, which in turn demonstrated the best activity against P. aeruginosa and multiple resistant subsets. Ceftolozane/tazobactam demonstrated considerable in vitro activity against P. aeruginosa including multiple resistance patterns, indicating that it could be an optional therapeutic agent against P. aeruginosa.
- | Journal: Antibiotic resistance pattern, capsular types, and molecular characterization of invasive isolates of Streptococcus pneumoniae in the south of Tunisia from 2012 to 2018. (Pubmed Central) - Feb 5, 2023
The highest proportions of antibiotic non-susceptible isolates were for penicillin, erythromycin, and tetracycline. Further molecular characteristics are required to monitor the genetic variations and to follow the emergence of resistant pneumococci for the post-vaccination era in Tunisia.
- Legionnaire (B / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5290;
- Disseminated Nocardia paucivorans infection in an immunocompetent host after SARS-CoV2: a case report and review of literature (B / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5284;
- Neuromyelitis optica mimicking isoniazid and ethambutol toxic optic neuropathy in a patient with tuberculous lymphadenitis (C / 01) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5278;
- Chronic cough and painless lump in clavicle of a Moroccan patient (B / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5245;
- First case of meningoencephalitis and bacteraemia due to Flavobacterium lindanitolerans (B / 01) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5130;
- M. hominis and U. urealyticum disseminated infection after hip replacement and shoulder plate synthesis in immune compromised host: a case report (B / 01) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5126;
- Congenital tuberculosis case: the reality of life (A / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5111;
- Fetroja (cefiderocol) / Shionogi
A central venous catheter-related Stenotrophomonas maltophilia bacteraemia successfully treated with a combination of cefiderocol systemic therapy and trimethoprim/sulfamethoxazole lock therapy (A / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5106;
- The drug, the bug and mug: how PK/PD index in the cerebrospinal fluid can optimise antibiotic treatment (A / 07) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5102;
- Infected rabbit bite due Actinobacillus capsulatus (A / 07) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5100;
- Septic abortion due to Streptococcus pneumoniae : a common pathogen in an uncommon location (A / 07) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5090;
- Pseudomonas aeruginosa community-acquired pneumonia: a case report and literature review (A / 06) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5070;
- tetracycline / Generic mfg.
A case of cellulitis with bacteraemia due to Campylobacter jejuni resistant to macrolide, fluoroquinolone and tetracycline (A / 05) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5059;
- Drug resistant serotype 19A pneumococcal empyema in a fully PCV-13 vaccinated child (A / 05) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5056;
- Invasive disease caused simultaneously by two different serotypes of Streptococcus pneumoniae (A / 05) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5055;
- Mycolicibacterium senegalense catheter-associated bacteraemia: a case report (A / 05) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5052;
- trimethoprim/sulfamethoxazole / Generic mfg.
A case report of trimethoprim/sulfamethoxazole resistant Burkholderia pseudomallei in a diabetic Filipino patient (A / 04) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5044;
- Polymicrobial MDR infection of the combat-related extremity wound in Ukrainian military (A / 03) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_5012;
- Exploring the impact of co-morbidities on empiric treatment of urinary tract infections and antimicrobial resistance in a large dataset (C / 04) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4962;
- Epidemiological changes in pneumococcal serotypes and antimicrobial susceptibility profiles eight years after the 13-valent pneumococcal conjugate vaccine introduction in the Valencian community: are we all talking about the same? (D / 12) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4523;
- Neutropaenic fever in allogeneic haematopoietic cell transplantation in the absence of antibacterial prophylaxis (C / 14) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4482;
- ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg., amoxycillin/clavulanate / Generic mfg.
Economic evaluation of (C / 15) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4460;
- ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg., amoxycillin/clavulanate / Generic mfg.
Efficacy of levofloxacin vs amoxicillin/clavulanate and ciprofloxacin in the outpatient management of low-risk febrile neutropaenia in children with cancer: a randomised control study (C / 15) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4458;
- In-class cross-reactivity among hospitalized patients with hypersensitivity reactions to fluoroquinolones (A / 16) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4332;
- Antimicrobial stewardship programme during COVID-19 pandemic: a success story (A / 14) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4283;
- Antimicrobial use for healthcare-associated pneumonia in the Philippines from 2017-2021: results from the global point prevalence survey (Global-PPS) (A / 11) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4232;
- levofloxacin / Generic mfg., ceftazidime / Generic mfg.
Model-informed exposure response analyses for ceftazidime and levofloxacin against Klebsiella pneumoniae and Pseudomonas aeruginosa in murine thigh infection models (A / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4123;
- A pharmacokinetic/pharmacodynamic (PK/PD) analysis of drug-resistant tuberculosis (DR-TB) therapy in Durban, South Africa (A / 08) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4122;
- Towards precision antibiotics: HsrA inhibitors exhibit strong bactericidal activities against Helicobacter pylori with minor effects on normal human microbiota (A / 05) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4047;
- PWAc1, a new phage recovered from sewage active alone and in combination with antimicrobials against high-risk OXA-72-producing Acinetobacter baumanni clone (A / 03) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_4041;
- Is assessing reactive oxygen species (ROS) using flow cytometry a good method to determine minimal inhibitory concentrations (MICs)? (C / 16) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_3618;
- Determination of Streptococcus pneumoniae serotypes and antibiotic resistance isolated from adult patients during the pandemic period (C / 11) - Feb 4, 2023 - Abstract #ECCMID2023ECCMID_3512;