levofloxacin / Generic mfg. 
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  • ||||||||||  Journal:  A Case of Thyroid Gland Abscess Caused by Brucella melitensis (Pubmed Central) -  Apr 28, 2024   
    If diagnosis is delayed, complications may develop due to involvement in almost every part of the body, depending on the affected organs and systems. In areas where brucellosis is endemic, patients with symptoms such as neck swelling, shortness of breath and difficulty in swallowing, thyroid tissue involvement due to brucellosis should definitely be considered etiologically.
  • ||||||||||  Biomarker, Journal:  Molecular Analysis of Antibiotic Resistance in CarbapenemResistant Pseudomonas aeruginosa Isolates Isolated from Clinical Samples (Pubmed Central) -  Apr 28, 2024   
    In areas where brucellosis is endemic, patients with symptoms such as neck swelling, shortness of breath and difficulty in swallowing, thyroid tissue involvement due to brucellosis should definitely be considered etiologically. In the study, identification of the bacterial isolates and their susceptibility to some antibiotics (imipenem, meropenem, aztreonam, amikacin, netilmicin, tobramycin, piperacillin, piperacillin/tazobactam, ceftazidime, cefepime, ciprofloxacin and levofloxacin) were determined by the VITEK
  • ||||||||||  levofloxacin / Generic mfg.
    Journal:  In-situ assembling novel N-Ti3C2/BiOClxBr1-x composites with enhanced photocatalytic degradation and nitrogen reduction activity. (Pubmed Central) -  Apr 27, 2024   
    Compared to that of BiOClxBr1-x, the maximum improvements of 1.16, 1.25 and 1.26 folds are severally confirmed for the photocatalytic degradation of levofloxacin, Rhodamine B, and methylene blue over N-Ti3C2/BiOClxBr1-x composites...Additionally, the stable photocatalytic properties of N-Ti3C2/BiOClxBr1-x are confirmed by three photocatalytic recycle tests on pollutant degradation and nitrogen reduction combined with X-ray diffraction patterns before and after three recycles. This study suggests that N-Ti3C2 is an efficient ornamentation for boosting photocatalytic activity ofBiOClxBr1-x, which can also be expanded as a promising modifier for other semiconductors.
  • ||||||||||  levofloxacin / Generic mfg.
    Journal:  Mechanochemically Induced Solid-State Transformations of Levofloxacin. (Pubmed Central) -  Apr 25, 2024   
    Dynamic vapor sorption studies of both LVXam samples showed comparable stability properties and crystallized to the most stable hemihydrate form upon analysis. In summary, this work contributed to the detailed understanding of solid-state transformations of essential fluoroquinolones while employing greener and more sustainable manufacturing methods.
  • ||||||||||  levofloxacin / Generic mfg., valacyclovir / Generic mfg., acyclovir / Generic mfg.
    Time to antibiotic administration in patients undergoing HSCT with neutropenic fever. () -  Apr 24, 2024 - Abstract #ASCO2024ASCO_6242;    
    Hypotheses for this delay include improper chart documentation, nurse training (delay in physician notification), and provider comfort (antimicrobials deferred to day team, ID consults). The latter is of particular concern given incidents of >10 hour delay to antibiotic initiation.
  • ||||||||||  levofloxacin / Generic mfg.
    Journal:  Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II. (Pubmed Central) -  Apr 23, 2024   
    Levofloxacin was used as a positive control...Our findings suggest that TLF-II combats UPEC-induced bladder infections by effectively mitigating bladder inflammation and preventing bacterial escape from fusiform vesicles into the cytoplasm. The findings suggest that TLF-II is a promising option for treating UTI and reducing its recurrence.
  • ||||||||||  ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg.
    Trial completion date, Trial primary completion date:  Ciprofloxacin Versus Levofloxacin in Stem Cell Transplant (clinicaltrials.gov) -  Apr 23, 2024   
    P2,  N=308, Active, not recruiting, 
    The findings suggest that TLF-II is a promising option for treating UTI and reducing its recurrence. Trial completion date: Apr 2024 --> Aug 2024 | Trial primary completion date: Apr 2024 --> Aug 2024
  • ||||||||||  levofloxacin / Generic mfg.
    Retrospective data, Journal:  A retrospective study of the efficacy and safety of levofloxacin in children with severe infection. (Pubmed Central) -  Apr 22, 2024   
    The effectiveness of levofloxacin use in children with serious infections is promising, especially for the treatment of multidrug-resistant bacteria. Adverse events occurring during the initiation of levofloxacin therapy in children are reported to be relatively common, but in this study, only a small percentage of them were possibly related to levofloxacin, and none of them were highly possibly related to levofloxacin.
  • ||||||||||  Invanz (ertapenem) / Merck (MSD)
    Trial primary completion date:  Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy (clinicaltrials.gov) -  Apr 22, 2024   
    P4,  N=100, Recruiting, 
    Adverse events occurring during the initiation of levofloxacin therapy in children are reported to be relatively common, but in this study, only a small percentage of them were possibly related to levofloxacin, and none of them were highly possibly related to levofloxacin. Trial primary completion date: Sep 2024 --> Mar 2025
  • ||||||||||  Journal:  Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou. (Pubmed Central) -  Apr 19, 2024   
    Gram-positive bacteria are the dominant bacteria in eye infections, followed by gram-negative bacteria and fungi. Considering the resistance of gram-negative bacteria to multiple drugs, monitoring of bacteria should be strengthened in eye bacterial infections for effective prevention and control to reduce complications caused by eye infections.
  • ||||||||||  levofloxacin / Generic mfg.
    Preclinical, Journal:  Developmental stage and infection status may affect drug distribution in the prostate of rats. (Pubmed Central) -  Apr 18, 2024   
    Dialysates of levofloxacin and cefradine were collected from the prostate gland and jugular vein and evaluated...The mean values in group B were lower than those in group A, and those in group C were higher than those in group B.The maturity of the prostate may affect the ability of the drug to cross the BPB. Infection may disrupt the BPB, affecting drug permeability.
  • ||||||||||  Xerava (eravacycline) / SOM Biotech, Ewha Womans University, PAION, Innoviva
    Journal:  Emergence of eravacycline heteroresistance in carbapenem-resistant Acinetobacter baumannii isolates in China. (Pubmed Central) -  Apr 15, 2024   
    Decreasing the expression of adeABC or adeRS by antisense RNA silencing significantly inhibited eravacycline heteroresistance. In conclusion, this study identified the emergence of eravacycline heteroresistance in CRAB isolates in China, which is associated with high expression of AdeABC and AdeRS.
  • ||||||||||  Pneumosil (10-valent pneumococcal conjugate vaccine) / Serum Institute of India
    ASSESSING NASOPHARYNGEAL STREPTOCOCCUS PNEUMONIAE CARRIAGE IN SALVADORAN CHILDREN UNDER 4: INFLUENCE OF PNEUMOCOCCAL CONJUGATE VACCINATION. (STATION 2) -  Apr 14, 2024 - Abstract #ESPID2024ESPID_637;    
    Comparison of nasopharyngeal carriage proportions between PCV10-vaccinated (31.5%) and PCV13-vaccinated (10%) children using the Z test revealed a statistically significant difference (p=0.00000372020)...The most prevalent serotype was 22F, followed by 23B and serotypes 19F and 19Fv. Both vaccinated and non-vaccinated cases showed 100% sensitivity to third-generation cephalosporin and vancomycin.
  • ||||||||||  levofloxacin / Generic mfg.
    Journal:  Nitrocellulose for Prolonged Permeation of Levofloxacin HCl-Salicylic Acid In Situ Gel. (Pubmed Central) -  Apr 13, 2024   
    The low viscosity of LvSa25Nc makes it appropriate for injectable treatments targeting periodontitis, while the higher viscosity of LvSa40Nc renders it appropriate for topical applications in acne treatment. Therefore, the nitrocellulose in situ gel loaded with combined levofloxacin HCl and salicylic acid emerges as a promising dosage form for treating acne and periodontitis.
  • ||||||||||  levofloxacin / Generic mfg., rifampicin / Generic mfg.
    Journal, Immunomodulating:  Immunomodulatory zymosan/?-carrageenan/ agarose hydrogel for targeting M2 to M1 macrophages (antitumoral). (Pubmed Central) -  Apr 12, 2024   
    Conclusively, PEO-CS-LEV/PLGA-QS core-shell nanofibers were shown to be a promising wound healing material that could drive the healing cascade through local co-delivery of LEV and QS to burn wounds. Seaweed derived carrageenan/ZM/agarose hydrogel was successfully prepared (@5?:?5 wt%) and was seen to support the growth of L929 cells (1
  • ||||||||||  Journal:  Antimicrobial resistance of avian pathogenic Escherichia coli isolated from broiler, layer, and breeder chickens. (Pubmed Central) -  Apr 10, 2024   
    Similarly, a significant phenotype-genotype correlation (p < 0.001) was observed between chloramphenicol and the tetB, and colistin with blaTEM and resistance gene of quinolone (qnrA)...We deciphered the complex nature of AMR in APEC populations. This information of molecular surveillance is useful to combat AMR in APEC and to contribute to manage APEC associated diseases and develop policies and guidelines to enhance the commercial chicken production.
  • ||||||||||  levofloxacin / Generic mfg.
    Retrospective data, Journal, Surgery:  Clinical Experience of Using a Combination of Dexamethasone and Levofloxacin After Cataract Surgery. (Pubmed Central) -  Apr 7, 2024   
    The prescribed regimen effectively managed the postoperative recovery of the participants, and the medication was well-tolerated. Our research found that a new combination of levofloxacin and dexamethasone, when used topically, may require a shorter treatment period, reducing the risk of antibiotic resistance and providing a safe alternative for endophthalmitis prevention.
  • ||||||||||  ciprofloxacin oral / Generic mfg., levofloxacin / Generic mfg., tetracycline / Generic mfg.
    Journal:  Antibiotic residues in pasteurised and Raw Cow's milk in Dhaka, Bangladesh. (Pubmed Central) -  Apr 5, 2024   
    pneumoniae strains are susceptible to vancomycin, linezolid, ertapenem, levofloxacin, moxifloxacin, rifampicin, and chloramphenicol. Notably, pasteurised milk samples contained enrofloxacin, levofloxacin and oxytetracycline, with groups P6 and P7 exceeding the Maximum Residue Limit for enrofloxacin, levofloxacin and ciprofloxacin (121?