albendazole / Generic mfg. 
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  • ||||||||||  triamcinolone acetonide / Generic mfg., albendazole / Generic mfg.
    Biomarker, Retrospective data, Journal:  Clinical Features and Prognostic Factors in Northern Chinese Patients with Peripheral Granuloma Type of Ocular Toxocariasis: A Retrospective Cohort Study. (Pubmed Central) -  Mar 5, 2022   
    The combination therapy of vitreoretinal surgery, steroids, and albendazole therapy may reduce inflammation and recurrence of OT effectively. Abbreviations: BCVA: best-corrected visual acuity; BFGF: basic fibroblast growth factor; CFT: central foveal thickness; CI: confidence interval; ELISA: Enzyme-linked immunosorbent assay; ERM: epiretinal membrane; IOP: intraocular pressure; IQR: interquartile range; IL: interleukin; LFM: laser flare meter; MH: macular hole; OCT: optical coherence tomography; OR: odds ratio; OT: ocular toxocariasis; RD: retinal detachment; TA: triamcinolone acetonide; TCLA: Toxocara canis larva crude antigen; TGF: transforming growth factor; VCAM: vascular cell adhesion molecule; VEGF: vascular endothelial growth factor.
  • ||||||||||  albendazole / Generic mfg.
    Clinical, Journal:  Case Report: Total Nephrectomy for Renal Hydatidosis. (Pubmed Central) -  Mar 3, 2022   
    The patient was discharged with albendazole treatment...Surgery remains the best therapeutic option. The use of ultrasonography improves the early detection of zoonosis, especially in pediatric patients, and favors the use of more conservative therapeutic techniques.
  • ||||||||||  ivermectin oral / Generic mfg., albendazole / Generic mfg.
    Clinical, Journal:  Case Report: Challenges for the Diagnosis and Treatment of Strongyloides stercoralis in Chronic Obstructive Pulmonary Disease Patients. (Pubmed Central) -  Mar 3, 2022   
    All the included patients were treated with albendazole, which is the second-line drug for S. stercoralis, and relapse of infection was observed in two patients by passing few months from the treatment...In COPD patients who are receiving steroids, screening and follow-up for strongyloidiasis should be considered as priorities. In addition, ivermectin, which is the first-line drug for strongyloidiasis, should be available in the region.
  • ||||||||||  ivermectin oral / Generic mfg., albendazole / Generic mfg.
    Clinical, Journal:  Effect of antihelminths with contrasting efficacy against gastrointestinal nematodes on the live-weight gain of young Nellore cattle. (Pubmed Central) -  Mar 1, 2022   
    In most of the samplings, the median EPGs were significantly lower (P < 0.05) in the group treated with albendazole...Because the main difference between the ivermectin and the control groups was the O. radiatum parasitism, most of the losses in the control group were possibly due to this nematode species. Nevertheless, the other nematodes species that occurred in relatively high intensities in control group could also have an additive effect in such losses.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  Improvement of Albendazole Bioavailability with Menbutone Administration in Sheep. (Pubmed Central) -  Feb 26, 2022   
    Regarding ABZSO, C, AUC and t values were similar after both treatments (ABZ or ABZ + MEN). The results obtained indicate that co-administration of ABZ and MEN may be an interesting and practical option to increase the efficacy of this anthelmintic.
  • ||||||||||  mebendazole / Generic mfg., albendazole / Generic mfg.
    Journal:  Therapy and Prevention for Human Toxocariasis. (Pubmed Central) -  Feb 26, 2022   
    Due to its wide availability and a lack of major side effects during short regimens, albendazole has become the drug of choice...Prophylactic measures in humans or companion animals are efficient and represent first-line treatments for the control of this zoonosis. Unfortunately, their implementation in areas or countries where toxocariasis epidemiology is driven by poverty is quite difficult or unrealistic.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  Disseminated microsporidiosis: An underdiagnosed and emerging opportunistic disease. (Pubmed Central) -  Feb 24, 2022   
    Disseminated microsporidiosis shows the potential to be cleared up by albendazole or fumagillin if they are detected and treated early. Based on a series of case reports, this review aims to present a current update on disseminated microsporidiosis with emphasis on the clinical manifestations based on the organ system infected, diagnostic approach and treatment of this devastating condition.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  Spinal cysticercosis: a rare cause of myelopathy. (Pubmed Central) -  Feb 24, 2022   
    Characteristic MRI features can facilitate preoperative diagnosis. Clinicians should be aware of this entity, and it should be included in the differential diagnosis of myelopathy.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  Splenic-preserving surgery in hydatid spleen: a single institutional experience. (Pubmed Central) -  Feb 22, 2022   
    All surgeries had albendazole before and after the operation 15 mg/kg/day...However, three patients failed to follow up within two years. Our experience with splenic hydatids prompts us to use splenic conservation surgery whenever possible instead of splenectomy.
  • ||||||||||  Retrospective data, Journal:  Costs and Prescribing Patterns of Anthelmintics in the United States Military: A Retrospective Analysis. (Pubmed Central) -  Feb 22, 2022   
    There were 15498 mebendazole prescriptions and 1327 praziquantel prescriptions...Annual costs for anthelmintic medications increased 16-fold during the study period, up to nearly $5000000 in fiscal year 2019, primarily driven by price increases in albendazole and mebendazole...Price increases in anthelmintic medications have significantly impacted the costs borne by the US government for treating parasitic infections. There are a substantial number of anthelmintic prescriptions in the US military health care system annually, suggesting a higher number of helminth infections than previously thought.
  • ||||||||||  dexamethasone / Generic mfg.
    Clinical, Journal:  Case Report: Angiostrongylus cantonesis Myelitis in Thailand. (Pubmed Central) -  Feb 19, 2022   
    Results of an immunochromatographic test kit were positive for Angiostrongylus cantonesis but negative for Gnathostoma spinigerum. After a 4-week course of albendazole combined with a tapering dose of dexamethasone, he achieved nearly complete recovery.
  • ||||||||||  Pulmonary Strongyloides in an Immunocompromised Patient (Area C, Hall F (North Building, Exhibition Level), Moscone Center) -  Feb 19, 2022 - Abstract #ATS2022ATS_4782;    
    Disseminated Strongyloides is a rare disease with variable presentation...Ivermectin is effective at treating the parasite with tolerable side effect profile compared to albendazole (Henriquez‐Camacho 2016). One must maintain a high index of suspicion to diagnose this disease, as missing a diagnosis can be fatal in immunocompromised patients.
  • ||||||||||  albendazole / Generic mfg.
    Progressive Dyspnea, Chronic Cough and Eosinophilia in Adolescent Girl (Area E, Hall F (North Building, Exhibition Level), Moscone Center) -  Feb 19, 2022 - Abstract #ATS2022ATS_1352;    
    Patient was started on course of Albendazole with repeat studies (spirometry, CT) planned for 3 months post treatment...Antibodies directed toward Strongyloides are an alternative diagnostic target with well understood pattern (IgG present 2-20 weeks post-infection). Treatment course is short and generally well tolerated, and thus should be considered even without conclusive evidence if clinical suspicion is high.
  • ||||||||||  ivermectin oral / Generic mfg., albendazole / Generic mfg.
    A Case of Strongyloides Stercoralis Induced Chronic Eosinophilic Pneumonia (Area F, Hall F (North Building, Exhibition Level), Moscone Center) -  Feb 19, 2022 - Abstract #ATS2022ATS_1033;    
    Her treatment course was significant for five rounds of ivermectin and one round of albendazole...Providers must be aware of strongyloides infection as a potential cause of CEP and should have high level of suspicion for strongyloides prior to initiating treatment. This is particularly relevant as immunosuppression from treatment with systemic steroids can precipitate a life threatening strongyloides hyperinfection syndrome that can carry a mortality rate of nearly 77% in immunocompromised hosts.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  An Artemisia cina n-hexane extract reduces the Haemonchus contortus and Teladorsagia circumcincta fecal egg count in naturally infected periparturient goats. (Pubmed Central) -  Feb 16, 2022   
    The lethal effects of Acn-h at 0.5, 1, 2, and 4 mg/mL on H. contortus adult stages were 31.6, 66.5, 81.3, and 86.9%, respectively (p < 0.05), showing similar efficacy at 2 and 4 mg/mL with albendazole (positive control group)...During the whole experiment, no significant differences in OMC or BC were observed in relation to the control group, excepting at day 23 (p < 0.05) for BC in the group treated with A. cina. Thus, Acn-h can be a useful natural alternative tool for the control of the nematodes H. contortus and T. circumcincta in periparturient goat flocks.
  • ||||||||||  mebendazole / Generic mfg., albendazole / Generic mfg.
    Journal:  Status and prospect of novel treatment options toward alveolar and cystic echinococcosis. (Pubmed Central) -  Feb 15, 2022   
    Next the conventional experimental projects and pharmacodynamic evaluation methods are systematically summarized and evaluated. The demands to optimize the construction of the echinococcosis model and improve the dynamic monitoring method in vivo are also discussed given the shortcomings of in vivo models and monitoring methods.
  • ||||||||||  albendazole / Generic mfg.
    Preclinical, Journal:  Heme oxygenase-1 modulates brain inflammation and apoptosis in mice with angiostrongyliasis. (Pubmed Central) -  Feb 12, 2022   
    The combination of albendazole (ABZ) and CoPP significantly decreased pro-inflammatory cytokines, tumor necrosis factor-α, interleukin (IL)-1β, IL-5, and IL-33 but significantly increased anti-inflammatory cytokines IL-10 and transforming growth factor-β...Thus, co-treatment with ABZ and CoPP prevented A. cantonensis-induced eosinophilic meningoencephalitis and its anti-apoptotic effect by promoting HO-1 signaling prior to BBB dysfunction. HO-1 induction might be a therapeutic modality for eosinophilic meningoencephalitis.
  • ||||||||||  NN1213 / Novo Nordisk
    Trial completion date, Trial primary completion date:  BEED: The Bangladesh Environmental Enteric Dysfunction Study (clinicaltrials.gov) -  Feb 11, 2022   
    P=N/A,  N=1575, Recruiting, 
    Further research is needed to elucidate the link between inflammation, UPR and ERS, and if these pathways offer potential for improved therapies of patients with AE. Trial completion date: Dec 2021 --> Jun 2022 | Trial primary completion date: Dec 2021 --> Jun 2022
  • ||||||||||  moxidectin / Generic mfg.
    Enrollment closed, Enrollment change:  Moxidectin for LF, Cote d'Ivoire (DOLF) (clinicaltrials.gov) -  Feb 11, 2022   
    P3,  N=164, Active, not recruiting, 
    Trial completion date: Dec 2021 --> Jun 2022 | Trial primary completion date: Dec 2021 --> Jun 2022 Enrolling by invitation --> Active, not recruiting | N=250 --> 164
  • ||||||||||  albendazole / Generic mfg.
    Enrollment closed, Trial completion date, Combination therapy:  DOLF IDA/Oncho: Safety and Efficacy of IDA for Onchocerciasis (clinicaltrials.gov) -  Feb 11, 2022   
    P2,  N=201, Active, not recruiting, 
    Enrolling by invitation --> Completed Enrolling by invitation --> Active, not recruiting | Trial completion date: Jan 2022 --> Jan 2023
  • ||||||||||  ASSOCIATION OF PLASMA BIOMARKERS WITH EARLY MORTALITY IN ADVANCED HIV INFECTION ([VIRTUAL]) -  Feb 7, 2022 - Abstract #CROI2022CROI_822;    
    Soluble inflammatory markers at ART initiation are associated with mortality in advanced HIV in sub-Saharan Africa, with distinct biomarker patterns depending on cause of death. Inflammatory biomarkers (CRP, IFN?, IL-5 and IP-10) were associated with increased all-cause mortality, while homeostatic and adaptive markers (IL-2, IL-23 and RANTES) were associated with reduced mortality.
  • ||||||||||  albendazole / Generic mfg.
    Journal:  Primary disseminated intraabdominal hydatidosis: a case report. (Pubmed Central) -  Feb 4, 2022   
    Therefore, it is recommended to follow such patients with imaging modalities and enzyme-linked immunosorbent assay for native antigen B (AgB). In addition, patients should undergo albendazole therapy postoperatively for 4 months.