 |
153 Diseases |  |
74 Trials |
|
74 Trials |  |
10107 News |  |
| «12345678910111213...8586» |
- | prednisolone / Generic mfg.
New P2 trial: The STOP Study: Silicosis Treatment Of Prednisolone (EUDRACT) - Dec 1, 2023
P2, N=10, Not yet recruiting, Sponsor: Alfred Health
.
- ||||||||| Aliqopa (copanlisib) / Bayer
Trial completion date, Trial termination, Combination therapy: CHRONOS-4: Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL) (clinicaltrials.gov) - Dec 1, 2023
P3, N=547, Terminated, Sponsor: Bayer
The addition of copanlisib to standard immunochemo therapy did not improve progression-free survival compared to the control arm. Base on the study results, company decided to terminate the study.
- | Carogra (carotegrast methyl) / Kissei, Eisai
Journal: Evaluation of the potential drug-drug interactions of carotegrast methyl with midazolam, prednisolone, or atorvastatin in healthy adults. (Pubmed Central) - Nov 30, 2023
Carotegrast methyl was classified as a moderate CYP3A4 inhibitor in humans. Carotegrast methyl might enhance the action of drugs that are metabolized by CYP3A4.
- || prednisolone / Generic mfg.
Trial completion date, Trial primary completion date: High-TeC: Nasal High-Flow in COPD (clinicaltrials.gov) - Nov 29, 2023
P=N/A, N=136, Recruiting, Sponsor: Marieke Duiverman
Carotegrast methyl might enhance the action of drugs that are metabolized by CYP3A4. Trial completion date: Jul 2023 --> Dec 2025 | Trial primary completion date: May 2023 --> Oct 2025
- | prednisolone / Generic mfg.
Retrospective data, Journal, Surgery: Toxic posterior segment syndrome with retinal vasculitis likely caused by intraocular cotton fiber after vitreoretinal surgery - a case report. (Pubmed Central) - Nov 27, 2023
This report describes an unusual diagnosis of TPSS after vitreoretinal surgery, most likely due to the presence of an intraocular cotton fiber. This excessive inflammation of the posterior segment usually responds to a course of topical and systemic steroids.
- | prednisolone / Generic mfg.
Journal: Clinical features and outcomes of patients with muscle-specific kinase antibody-positive myasthenia gravis in Japan. (Pubmed Central) - Nov 12, 2023
The refractory group had a lower age of onset, higher severity scores, and higher maximum daily doses of oral prednisolone compared to the nonrefractory group. The outcomes for MuSK-MG patients in Japan are not favorable, indicating the need for more aggressive treatment.
- ||| Rinvoq (upadacitinib) / AbbVie
Trial primary completion date: SELECT-TAK: A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK) (clinicaltrials.gov) - Nov 8, 2023
P3, N=56, Recruiting, Sponsor: AbbVie
The outcomes for MuSK-MG patients in Japan are not favorable, indicating the need for more aggressive treatment. Trial primary completion date: Aug 2027 --> Apr 2024
- || prednisolone / Generic mfg., azathioprine / Generic mfg.
Review, Journal: A Rare Case of Sarcoidosis Presenting as an Isolated Breast Mass and Pain: A Case Report and Literature Review. (Pubmed Central) - Nov 3, 2023
During treatment, the mass size decreased and the pain substantially improved. CONCLUSIONS It is important to consider sarcoidosis in a patient who presents with only pain and swelling in the breast to ensure early diagnosis and initiate treatment, improving the patient's overall prognosis.
- ||| farletuzumab ecteribulin (MORAb-202) / Eisai
Enrollment change: MORAb-202-G000-201: A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FR?)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types (clinicaltrials.gov) - Nov 1, 2023
P1/2, N=142, Recruiting, Sponsor: Eisai Inc.
CONCLUSIONS It is important to consider sarcoidosis in a patient who presents with only pain and swelling in the breast to ensure early diagnosis and initiate treatment, improving the patient's overall prognosis. N=66 --> 142
- | prednisolone / Generic mfg., pregabalin / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date, Surgery: Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin (clinicaltrials.gov) - Nov 1, 2023
P=N/A, N=63, Completed, Sponsor: Zagazig University
N=66 --> 142 Recruiting --> Completed | Trial completion date: Jul 2021 --> Aug 2023 | Trial primary completion date: Jun 2021 --> Aug 2023
- | prednisolone / Generic mfg., amoxicillin / Generic mfg.
Journal: Trends in medication use at the onset of and during the COVID-19 pandemic in the Republic of Ireland: an interrupted time series study. (Pubmed Central) - Oct 30, 2023
Dispensing of amoxicillin products and oral prednisolone were lower than forecasted in the months following the pandemic's onset, particularly during winter 2020/2021. There was a spike in dispensing for many long-term medications in March 2020, while pandemic restrictions likely contributed to reductions for other medications.
- | Nucala (mepolizumab) / GSK
Journal: Eosinophilic granulomatous with polyangiitis complicated by swelling of the oral cavity floor and cervical soft tissue as initial manifestation mimicking IgG4-related disease: A case report. (Pubmed Central) - Oct 30, 2023
The patient's symptoms improved after these treatments, and the eosinophil count and inflammatory marker levels declined. When swelling of the oral cavity floor and cervical soft tissue following an increase in eosinophilia and allergic symptoms occurs, it is crucial to consider the likelihood of eosinophilic granulomatous polyangiitis and collaborate with otolaryngologists and dentists to ensure its prompt identification.
- | prednisolone / Generic mfg., cyclophosphamide / Generic mfg.
Retrospective data, Journal: Antineutrophil cytoplasmic antibody-associated vasculitis with predominant truncal muscle weakness: a retrospective case series. (Pubmed Central) - Oct 30, 2023
However, there are notable differences between AAV associated myopathy vs. inflammatory myositis like dermatomyositis; (1) the absence of elevated CK levels, (2) the presence of complications in other organs, (3) distinct pathological findings, and (4) severe outcomes. Awareness that AAV patients with muscle involvement could have a subtype of AAV that seriously affects various organs is critical for an accurate diagnosis and effective therapeutic management.
- || Olumiant (baricitinib) / Incyte, Eli Lilly, Dupixent (dupilumab) / Sanofi, Regeneron, Opzelura (ruxolitinib cream) / Incyte, Maruho
Retrospective data, Review, Journal: Treatments for alopecia areata: a network meta-analysis. (Pubmed Central) - Oct 27, 2023
We also found that the impact of other treatments on hair regrowth is very uncertain. Evidence for health-related quality of life is still scant.
- | Comirnaty (tozinameran) / Pfizer, Fosun Pharma, BioNTech
Journal: A Case of Neuroretinitis Following COVID-19 Vaccination. (Pubmed Central) - Oct 23, 2023
The neuroretinitis resolved gradually after taking azithromycin and prednisolone orally. This is the first report of unilateral neuroretinitis following COVID-19 vaccination, implying a potential association between the mRNA vaccine and neuroretinitis.
- | Journal: Pemphigus Vegetans of Hallopeau: A Case Report. (Pubmed Central) - Oct 16, 2023
It remains debatable whether surgical trauma and radiology procedures such as angiographies (4) well as ACE-inhibitor drugs (5) triggered or aggravated the pemphigus. Early recognition and correct diagnosis of this rare type of pemphigus allows us to treat and control the disease successfully with lower doses of steroids, reducing complications to the minimum.
- |||| Aliqopa (copanlisib) / Bayer
Trial primary completion date, Combination therapy: CHRONOS-4: Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL) (clinicaltrials.gov) - Oct 12, 2023
P3, N=551, Active, not recruiting, Sponsor: Bayer
Early recognition and correct diagnosis of this rare type of pemphigus allows us to treat and control the disease successfully with lower doses of steroids, reducing complications to the minimum. Trial primary completion date: Mar 2024 --> Sep 2023
- ||| Rinvoq (upadacitinib) / AbbVie
Trial primary completion date: SELECT-TAK: A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK) (clinicaltrials.gov) - Oct 6, 2023
P3, N=56, Recruiting, Sponsor: AbbVie
Trial primary completion date: Mar 2024 --> Sep 2023 Trial primary completion date: Apr 2024 --> Aug 2027
- | prednisolone / Generic mfg.
Retrospective data, Journal: Long-term follow-up of allergic bronchopulmonary aspergillosis treated with glucocorticoids: A study of 182 subjects. (Pubmed Central) - Oct 4, 2023
Age, female sex, peripheral blood eosinophilia and the extent of bronchiectasis predicted ABPA exacerbations. The optimal serum total IgE cut-off for defining ABPA response and exacerbations is a 20% decline and a 50% increase, respectively.
- | prednisolone / Generic mfg., cyclophosphamide / Generic mfg.
Enrollment closed: Treatment Effects of Chinese Medicine (Yi-Qi-Qing-Jie Herbal Compound) Combined With Immunosuppression Therapies in IgA Nephropathy Patients With High-risk of ESRD (clinicaltrials.gov) - Oct 1, 2023
P2/3, N=60, Active, not recruiting, Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
The optimal serum total IgE cut-off for defining ABPA response and exacerbations is a 20% decline and a 50% increase, respectively. Recruiting --> Active, not recruiting
- | prednisolone / Generic mfg.
Journal: Prevalence, Clinical Profiles, and Prognosis of Stiff-Person Syndrome in a Japanese Nationwide Survey. (Pubmed Central) - Sep 27, 2023
The symptom onset to the diagnosis of SPS was longer in patients with high-titer GAD65 antibodies than in those with low-titer GAD65 antibodies. The outcome of patients with SPS was generally favorable, but more aggressive immunotherapies are necessary for GAD65-positive patients with SPS.
- Olumiant (baricitinib) / Incyte, Eli Lilly, Rinvoq (upadacitinib) / AbbVie
Safety and Effectiveness in Cycling Between Non-Selective and Selective JAKi in a Multi-Center Registry of Rheumatoid Arthritis in the Middle East (Poster Hall; in person) - Sep 23, 2023 - Abstract #ACRConvergence2023ACR_Convergence_4119;
We evaluated the overall safety of JAKis in the Middle Eastern population, as well as the clinical efficacy of cycling from Tofacitinib (Tofa) or Baricitinib (Bari) to Upadacitinib (Upa)...All patients had previously received csDMARD, however 56% received bDMARD and 59% received oral prednisolone... Our findings show that switching from non-selective JAKi to selective JAKi is feasible and safe, and that it may improve disease activity outcomes in patients who have failed to achieve low disease activity or remission with a previous JAKi.
- Orencia (abatacept) / BMS, Actemra IV (tocilizumab) / Roche, JW Pharma, Cimzia (certolizumab pegol) / Astellas, UCB
Certolizumab-pegol, Abatacept, Tocilizumab or Active Conventional Therapy in Early Rheumatoid Arthritis: 48 Week Patient-reported Outcomes of the NORD-STAR Trial (Poster Hall; in person) - Sep 23, 2023 - Abstract #ACRConvergence2023ACR_Convergence_2898;
P4
Our findings show that switching from non-selective JAKi to selective JAKi is feasible and safe, and that it may improve disease activity outcomes in patients who have failed to achieve low disease activity or remission with a previous JAKi. In this investigator-initiated, randomized, open-label study (NCT01491815), patients with treatment-na
- | thalidomide / Generic mfg., zoledronic acid / Generic mfg.
Trial completion: A multicentre randomised phase III study of low-dose thalidomide, prednisolone and zoledronic acid versus prednisolone and zoledronic acid for post-autologous stem cell transplant (ASCT) maintenance therapy in patients with multiple myeloma (MM6) (EUDRACT) - Sep 22, 2023
P3, N=250, Completed, Sponsor: Australasian Leukaemia and Lymphoma Group
In this investigator-initiated, randomized, open-label study (NCT01491815), patients with treatment-na Active, not recruiting --> Completed
- | Mavenclad (cladribine) / EMD Serono
Journal: Oral cladribine treatment and idiosyncratic drug-induced liver injury in multiple sclerosis. (Pubmed Central) - Sep 14, 2023
A causality assessment of the role of prednisolone and OC was performed using the updated Roussel Uclaf Causality Assessment Method which also included a negative re-exposure test for OC during the second OC treatment cycle 1?year later. Our observations suggest that prednisolone or interactions between prednisolone and OC are more likely to foster development of iDILI rather than OC treatment itself.
- | prednisolone / Generic mfg.
Journal: Demographics and treatment of patients with primary nephrotic syndrome in Japan using a national registry of clinical personal records. (Pubmed Central) - Sep 11, 2023
The present oral prednisolone use (mean dose, mg/day) was 87.2% (21.2), 80.9% (20.0), and 77.5% (18.8) of patients in the MCD, FSGS, and MN, respectively. The national registry of clinical personal records of primary NS could provide an informative insight into the characteristics, clinical features, and treatment approaches for patients with primary NS in Japan.
- || prednisolone / Generic mfg.
Clinical, Journal: Effect of Oral Prednisolone on Pain after Tonsillectomy with Sutures: A Randomized Clinical Trial. (Pubmed Central) - Sep 11, 2023
However, there is no consensus on the analgesic role of oral corticosteroids for post-tonsillectomy pain. The present study showed that oral prednisolone is effective on post-operative pain compared to a placebo.
- | Humira (adalimumab) / AbbVie
Journal: Three cases of subcorneal pustular dermatosis with immunohistochemical examinations. (Pubmed Central) - Sep 7, 2023
In case 2, a 70-year-old woman who had been treated for rheumatoid arthritis with adalimumab, salazosulfapyridine, and leflunomide developed 3- to 5-mm pustules on her trunk and thighs 4?days after flu vaccination...He was given oral prednisolone therapy, which was effective for the small pustules and some ulcers...Positive stainings for interleukin 8, interleukin 36?, and phospho-extracellular signal-regulated kinases 1 and 2 were observed in the upper layers of the epidermis below the pustules. Although the pathogenesis of subcorneal pustular dermatosis has not been clarified, the current results suggest that a variety of inflammatory cells, including those responsible for both innate and acquired immunity, are involved in the accumulation of neutrophils in subcorneal pustular dermatosis.
- | Comirnaty (tozinameran) / Pfizer, Fosun Pharma, BioNTech
Journal: A case of persistent, confluent maculopapular erythema following a COVID-19 mRNA vaccination is possibly associated with the intralesional spike protein expressed by vascular endothelial cells and eccrine glands in the deep dermis. (Pubmed Central) - Sep 7, 2023
As she had no episode of COVID-19 infection, it is highly likely that the spike protein was derived from the mRNA vaccine and it might be the cause of the development and persistence of her skin lesions. Her symptoms were prolonged and intractable until oral prednisolone was given.
- | prednisolone / Generic mfg., prednisone / Generic mfg.
Enrollment change, Head-to-Head: ADAPTinMCN: Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy (clinicaltrials.gov) - Sep 6, 2023
P4, N=64, Recruiting, Sponsor: University of Aarhus
Her symptoms were prolonged and intractable until oral prednisolone was given. N=96 --> 64
- | Keytruda (pembrolizumab) / Merck (MSD)
Journal, Metastases: A CASE OF RAPIDLY PROGRESSIVE RETINOPATHY ASSOCIATED WITH PEMBROLIZUMAB IMMUNOTHERAPY FOR METASTATIC UROTHELIAL CARCINOMA. (Pubmed Central) - Sep 2, 2023
We reported a case of rapidly progressive retinopathy that may have been triggered by pembrolizumab immunotherapy for metastatic urothelial carcinoma. High-dose corticosteroid pulse therapy was effective in reversing photoreceptor damage.
- | prednisolone / Generic mfg., tofacitinib / Generic mfg.
Journal: Tofacitinib versus oral prednisolone for induction of remission in moderately active ulcerative colitis (ORCHID): A prospective, open-label, randomized, pilot study. (Pubmed Central) - Sep 1, 2023
High-dose corticosteroid pulse therapy was effective in reversing photoreceptor damage. In patients with moderately active ulcerative colitis, there was no difference in the efficacy and safety of tofacitinib and oral prednisolone for induction of remission at 8 weeks.
- prednisolone / Generic mfg., carboplatin / Generic mfg., paclitaxel / Generic mfg.
A rare case of multiorgan autoimmunity associated with thymoma: TAMA (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_3598;
It is considered necessary for disease control of TAMA to reduce the volume of thymoma as much as possible by thymectomy and chemotherapy. Narrowband-UVB is known to enhance the regulatory T cell proliferation, and it has been reported that narrowband-UVB is highly effective in acute GVHD skin lesions.
- Resistant Lichen Planopilaris: expect the unexpected (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_3409;
To conclude, it is important to appreciate the broad clinical spectrum of LLP, occasionally affecting hair follicles on areas besides scalp and not always presenting with classical symptoms of pruritis and trichodynia. Due to LLP
- Comirnaty (tozinameran) / Pfizer, Fosun Pharma, BioNTech
Symmetrical Drug Related Intertriginous and Flexural Exanthema (SDRIFE) after first dose of Pfizer-BioNTech COVID-19 vaccine: A novel report (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_3098;
To date, there have been only a handful of reports of SDRIFE due to COVID-19 vaccination, specifically Pfizer-BioNTech COVID-19 vaccine. Our case substantiates the previous reports of SDRIFE due to Pfizer-BioNTech COVID-19 vaccination.
- prednisolone / Generic mfg.
Lazarine Leprosy over pre-existing anetodermic plaques presenting with renal system involvement and electrolyte disturbance (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_3073;
Three months after starting MDT and one week after tapering oral Prednisolone to 20 mg, the patient experienced abrupt onset spontaneous oozy ulcers across all of the pre-existing anetodermic plaques along with constitutional symptoms... Early diagnosis is necessary to treat mycobacterial infections and reactional episodes to stop the spread of infection and prevent disabilities associated with Leprosy.
- prednisolone / Generic mfg., minocycline / Generic mfg., azathioprine / Generic mfg.
Liquid Vitamin E Injection for Cosmetic Facial Rejuvenation and Disaster Lipogranuloma of the Face: A case report and literature review (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2918;
The treatment with oral prednisolone 50 mg per day was initiated for 4 weeks. After two weeks of oral corticosteroid administration, there was no significant therapeutic response and inevitably azathioprine 50 mg twice daily and minocycline 100 mg daily were added to the patient
- Cosentyx (secukinumab) / Novartis
Secukinumab as a Therapeutic Option for Grover's Disease: A Case Report of Transient Acantholytic Dermatosis (Grover's Disease) Associated with COVID-19 Infection in a Patient with Guttate Psoriasis (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2799;
Treatment involved localized application of topical preparations containing calcipotriol, urea, and polidocanol, as well as full-body phototherapy with UVB-311nm and seawater baths...In November 2022, the patient was prescribed oral prednisolone at a daily dose of 10 mg for four weeks, followed by a gradual dose reduction... The literature discusses a potential causal relationship between viral infections and the development of Grover
- Ebglyss (lebrikizumab) / Roche, Almirall, Eli Lilly
Recapture of response with lebrikizumab: an evaluation of patients from ADvocate1 and ADvocate2 (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2483;
P3
Most of these patients recaptured EASI 75 upon readministration of lebrikizumab. Additional data are needed to confirm this finding due to the limitations of this analysis including a low number of patients, as observed results, differing times of assignment to the escape arm, and an unblinded readministration period.
- prednisolone / Generic mfg.
Unraveling the Similarities: Cutaneous Polyarteritis Nodosa Masquerading as Calciphylaxis (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2472;
Its clinical presentation can mimic other dermatological conditions, posing a diagnostic challenge. Calciphylaxis, characterized by ischemic skin necrosis due to microvascular calcification, shares similarities with cPAN, particularly in patients with chronic kidney disease.
- metformin / Generic mfg.
Metformin-Induced Generalized Bullous Fixed-Drug Eruption with a Positive Dechallenge-Rechallenge Test: A Case Report and Literature Review (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2400;
Metformin dosage was stopped and lesions were treated with topical clobetasol propionate and oral prednisolone and cyclosporine-A. Due to the popularity of metformin, clinicians need to be aware of uncommon drug reactions for proper diagnosis and treatment.
- tadalafil / Generic mfg.
tadalafil as agep culprit (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2358;
The EUROSCAR study group score, an european project dedicated to severe cutaneous adverse reactions was also applied. Our case was classified as 10 points.
- Rituxan (rituximab) / Biogen, Zenyaku Holdings, Roche
Case report: Successful treatment of DRESS with narrow-band UVB phototherapy (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_2304;
Although the pathogenesis of DRESS/DIHS remains unknown in detail, it is generally regarded as a T-cell-mediated hypersensitivity reaction. The marked increase in the frequencies of regulatory T cell (Treg) is specifically found in the acute phase of DRESS/DIHS, but the frequencies of Treg decrease and their function is impaired in the chronic phase.
- | prednisolone / Generic mfg., acyclovir / Generic mfg.
Journal: Ramsay Hunt Syndrome with Pharyngolaryngeal Involvement Mimicking Acute Stroke: A Case Report. (Pubmed Central) - Aug 28, 2023
Previous history of hypertensive crises and myocardial infarction may influence a diagnosis of Ramsay Hunt syndrome, especially when it has atypical presentation. However, this diagnosis should be considered in patients with unilateral multiple cranial nerve palsies.
- || prednisolone / Generic mfg.
Review, Journal: Epithelioid hemangioma (ALHE) on the tongue of an infant treated with oral corticosteroids: A case report and review of the literature. (Pubmed Central) - Aug 28, 2023
Surgery had been considered to be the best treatment modality for ALHE. We report the case of a 6-month-old boy with ALHE on his tongue that was treated successfully with oral prednisolone.
- | prednisolone / Generic mfg.
Journal: Clinical standards for the diagnosis and management of asthma in low- and middle-income countries. (Pubmed Central) - Aug 27, 2023
Oral theophylline should be restricted for use in situations where it is the only bronchodilator treatment option available. These first consensus-based clinical standards for asthma management in LMICs are intended to help clinicians provide the most effective care for people in resource-limited settings.
- || Columvi (glofitamab-gxbm) / Roche, Rituxan (rituximab) / Roche
Enrollment closed: COALITION: A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL) (clinicaltrials.gov) - Aug 23, 2023
P1/2, N=80, Active, not recruiting, Sponsor: Peter MacCallum Cancer Centre, Australia
These first consensus-based clinical standards for asthma management in LMICs are intended to help clinicians provide the most effective care for people in resource-limited settings. Recruiting --> Active, not recruiting
- | Corifact (human coagulation factor XIII) / CSL Behring
Journal: A case of (Pubmed Central) - Aug 22, 2023
Recruiting --> Active, not recruiting Emergency transcatheter arterial embolisation was performed and coagulation factor XIII concentrates (Fibrogammin P
- | prednisolone / Generic mfg.
New P2 trial: The STOP Study: Silicosis Treatment Of Prednisolone (EUDRACT) - Aug 13, 2023
P2, N=10, Not yet recruiting, Sponsor: Alfred Health
- || Zyclara (imiquimod) / Mochida, Viatris, Bausch Health
Clinical, Journal: Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model. (Pubmed Central) - Aug 11, 2023
Oral prednisolone suppresses IMQ-induced skin inflammation, which underlines the value of this cutaneous challenge model in clinical pharmacology studies of novel anti-inflammatory compounds. In these studies, prednisolone can be used as a benchmark.