prednisolone / Generic mfg. 
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 153 Diseases   74 Trials   74 Trials   10114 News 


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  • ||||||||||  triamcinolone acetonide / Generic mfg., Decadron (dexamethasone) / Merck (MSD)
    Journal:  Intratympanic Triamcinolone Acetonide as Treatment Option for Idiopathic Sudden Sensorineural Hearing Loss. (Pubmed Central) -  May 25, 2020   
    While the exact role of intratympanic injections requires additional trials, triamcinolone resulted in similar outcomes compared to studies using dexamethasone or methylprednisolone. Due to favorable pharmacological properties, triamcinolone represents a safe and efficacious alternative for intratympanic treatment in idiopathic sensorineural hearing loss.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  A case of eosinophilic fasciitis and generalized morphea overlap. (Pubmed Central) -  May 25, 2020   
    Although he had been treated with oral prednisolone at another hospital, skin stiffness relapsed during tapering of prednisolone...However, cases of concurrent eosinophilic fasciitis and generalized morphea are rare. In the present case, CD34 was differentially expressed in both lesions, suggesting eosinophilic fasciitis and morphea are separate diseases with different origin of mesenchymal cells.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  Risk Factors and Treatment Types for Asthma Severity Among Adult Patients. (Pubmed Central) -  May 24, 2020   
    For the treatment type given to the patients, oxygen and prednisolone were highly distributed drugs to the patients in chronic illness, medication and follow-up clinic of the University of Gondar Teaching Hospital (UOGTH) which were expressed by 73.5% and 35.5%, respectively...Generally, the study presented the most common asthma symptoms and treatment types correspondingly. The study also showed that demographic, environmental, genetic, and health-related factors have a significant effect on asthma severity.
  • ||||||||||  tacrolimus / Generic mfg.
    Journal:  Membranous nephropathy caused by rheumatoid arthritis. (Pubmed Central) -  May 23, 2020   
    Based on assessments for differentiating PMN from secondary MN (SMN), the diagnosis of the present case was incompatible with PMN. Taken together, we consider that SMN in the present case was due to RA itself rather than drug-induced MN.
  • ||||||||||  prednisolone / Generic mfg., methylprednisolone oral / Generic mfg., cyclosporine / Generic mfg.
    Clinical, Journal:  Pathological findings of progressive renal involvement in a patient with TAFRO syndrome. (Pubmed Central) -  May 23, 2020   
    She was treated with methylprednisolone pulse (500 mg/day) and oral prednisolone (60 mg/day) therapy...Cyclosporine was added to prevent relapse...However, there are few reports of pathologically confirmed cases of progressive renal involvement in TAFRO syndrome. The relationship between VEGF expression in renal tissue and the pathogenesis of renal injury in TAFRO syndrome was investigated in the present case.
  • ||||||||||  prednisolone / Generic mfg., methylprednisolone oral / Generic mfg., mycophenolate mofetil / Generic mfg.
    Clinical, Journal:  A case of membranous nephropathy diagnosed with lupus nephritis 11 years after onset. (Pubmed Central) -  May 23, 2020   
    Methylprednisolone pulse therapy was started followed by oral administration of prednisolone...Steroid therapy combined with administration of mycophenolate mofetil led to an incomplete remission...Furthermore, immunofluorescence studies confirmed the presence of IgG1-4 in the first biopsy and tubuloreticular inclusions (TRIs) were revealed using electron microscopy. The present case represents the possibility that characteristic pathological findings of lupus nephritis, including TRIs, can reveal themselves before a diagnosis of SLE.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Clinical guideline, Journal:  Alcohol-related liver disease. Clinical practice guidelines. Consensus document sponsored by AEEH. (Pubmed Central) -  May 23, 2020   
    There are no specific treatments, and the only treatment that increases life expectancy in alcoholic hepatitis is prednisolone...This paper aims to answer the key questions for the clinical practice of Gastroenterology, Hepatology, as well as Internal Medicine and Primary Health Centres, making the most up-to-date information regarding the management and treatment of ARLD available to health professionals. These guidelines provide evidence-based recommendations for the clinical management of this disease.
  • ||||||||||  Decadron (dexamethasone) / Merck (MSD), Avelox (moxifloxacin) / Bayer
    [VIRTUAL] Safety and Efficacy of Intracameral Vs Intravitreal Vs Topical Steroid, Antibiotic, and NSAID after Cataract and Trabecular Bypass Surgery (VM-1,Virtual Room 7) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_3366;    
    132 eyes received injection of dexamethasone-moxifloxacin-ketorolac into the anterior chamber (AC DMK) then once a day topical combination prednisolone, antibiotic, and NSAID; 234 eyes received pars plana intravitreal injection of triamcinolone-moxifloxacin-vancomycin (PP TMV) then once a day combination drops; and 249 eyes received a traditional prednisolone, antibiotic, and NSAID drop regimen...AC DMK and topical groups showed greater reduction in glaucoma medications than PP TMV. AC DMK is safe and effective for patients with glaucoma undergoing cataract surgery with trabecular microbypass stent insertion.
  • ||||||||||  Decadron (dexamethasone) / Merck (MSD), Dexycu (dexamethasone intraocular injection) / EyePoint Pharma, Ocumension Therap
    [VIRTUAL] Evaluation of Intraoperative Use of Dexycu on the Signs and Symptoms of Dry Eye (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_2139;    
    Purpose To evaluate the impact of intraoperative Dexycu (9% dexamethasone) administered intraoperatively during cataract surgery on the postoperative signs and symptoms of dry eye...The standard postoperative cataract regimen included topical gatifloxacin and topical prednisolone acetate...Standard regimen of topical steroid and antibiotic does not improve postoperative dry eye signs. Additional studies should be done to assess if Dexycu without the use of concurrent topical steroid impacts dry eye signs and symptoms.
  • ||||||||||  Avelox (moxifloxacin) / Bayer
    [VIRTUAL] Herpes Zoster Ophthalmicus in a Young Individual Taking High Dose L-Arginine and Anabolic Steroids (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_2130;    
    Conclusion Anabolic steroids have been demonstrated in several studies to suppress immune function while L-Arginine has been associated with the replication and virulence of herpes zoster. Thus it is possible that anabolic steroids in conjunction with increased L-arginine intake may have precipitated a HZO in a previously healthy, immunocompetent individual.
  • ||||||||||  Rhopressa (netarsudil) / Aerie Pharma
    [VIRTUAL] Use of Netarsudil to Improve Endothelial Cell Function before and after DMEK Surgery (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_2051;    
    With still NI, valacyclovir was started for possible herpetic endotheliitis...Conclusion We share this case to demonstrate the efficacy of netarsudil, a commercially available rho-kinase inhibitor in the USA, in improving corneal edema in patients with iatrogenic endothelial cell loss in from LPI and DMEK. This is currently an off-label use of netarsudil and we hope cases like this will encourage further reports and clinical trials.
  • ||||||||||  Decadron (dexamethasone) / Merck (MSD)
    [VIRTUAL] To Evaluate the Use of the Hyper-CL Contact Lens for Patients with Corneal Edema (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_2029;    
    Conclusion The Hyper-CL contact lens is a practical and well-tolerated therapeutic solution to treat post-operative corneal edema in patients not using post-operative steroid drops. Further uses of this contact lens in conditions such as bullous keratopathy, recurrent corneal erosions and corneal infections needs to be explored.
  • ||||||||||  prednisolone / Generic mfg., methylprednisolone oral / Generic mfg.
    [VIRTUAL] Safety and Efficacy of LASEK in Myopic Patients with a History of Keloids (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_1959;    
    Of the 16 eyes in the study, 2 eyes developed trace haze which resolved with topical steroids. Conclusion LASEK with intraoperative MMC with postoperative oral steroids and a long taper of topical steroids is a safe, effective, and predictable technique for correcting all grades of myopia in patients with dermatological keloids.
  • ||||||||||  doxycycline / Generic mfg., Pierre Fabre
    [VIRTUAL] Corneal Keloid Formation after Photorefractive Keratectomy in a Young Patient (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_1911;    
    Throughout this time, he was compliant with his post operative antibiotic and steroid regimen (Gatifloxacin gtt and Prednisolone Forte taper)...Patient underwent epithelial scraping of this area and was started on frequent steroids and antibiotics in addition to doxycycline and vitamin C for corneal healing...Conclusion Very few case reports exist of acquired corneal keloid after corneal surgery or ocular trauma. This lesion was related to the corneal epithelial migration and healing after PRK, with likely contribution from the corneal abrasion 1 week post operatively, manual scraping during surgery without ETOH, and/or bandage lens contact with the cone apex.
  • ||||||||||  prednisolone / Generic mfg.
    [VIRTUAL] Efficacy of Topical Steroid Versus Oral Steroid in the Treatment of Acute Ocular Chemical Burns. (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_1848;    
    Results Mean trunks/quadrant were 7.5 3.42; 5.00 2.16 and 4.25 1.5 in control group,topical and combined treatment respectively(p=0.03).Mean neo-vassels/quadrant were 54.25 24.34; 8.25 4.27 and 5.25 2.06 in control group,topical and combined treatment respectively(p=0.007).Mean inflammatory cells was in topical and combined treatment was 1262 822.26 and 728 396.79 respectively(p=0.48). Conclusion Combined treatment is better than topical corticosteroids alone in preventing corneal neovascularization and in reducing inflammation after acute chemical ocular burns in a rats model.
  • ||||||||||  prednisolone / Generic mfg.
    [VIRTUAL] Comparison of Corticosteroids Treatment Effects in Corneal Alkali-Burn Injury in Rats (VM) -  May 23, 2020 - Abstract #ASCRSASOA2020ASCRS-ASOA_1821;    
    Results Mean trunks/quadrant were 7.5 3.42; 5.00 2.16 and 4.25 1.5 in control group,topical and combined treatment respectively(p=0.03).Mean neo-vassels/quadrant were 54.25 24.34; 8.25 4.27 and 5.25 2.06 in control group,topical and combined treatment respectively(p=0.007).Mean inflammatory cells was in topical and combined treatment was 1262 822.26 and 728 396.79 respectively(p=0.48). Conclusion Combined treatment is better than topical corticosteroids alone in preventing corneal neovascularization and in reducing inflammation after acute chemical ocular burns in a rats model.
  • ||||||||||  prednisolone / Generic mfg.
    [VIRTUAL] PREDICTIVE FACTORS FOR INSUFFICIENT RESPONSE TO INITIAL TREATMENT OR RECURRENCE IN PATIENTS WITH LUPUS ENTERITIS () -  May 22, 2020 - Abstract #EULAR2020EULAR_4186;    
    Furthermore, patients who initiated glucocorticoids (GCs) at a lower dose (less than or equal to 0.6mg/kg prednisolone equivalent dose (PEQ)) was significantly more frequent in poor response group ( Table 2 )... Lower level of CH50 and initial treatment with GCs at a lower dose were identified as prognostic factors associated with poor response to initial therapy or recurrence in LE.
  • ||||||||||  Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
    [VIRTUAL] TAKAYASU’S ARTERITIS PRESENTING WITH UNILATERAL DIGITAL CLUBBING IN A 23 YEAR-OLD MALE (Poster View) -  May 22, 2020 - Abstract #EULAR2020EULAR_3840;    
    He also received methotrexate 10 mg PO once weekly and rituximab 750 mg IV stat; another dose of rituximab was given two weeks later... In all four cases of Takayasu arteries presenting with unilateral clubbing, patients’ clinical condition including presence of clubbing improved after initiation of immunosuppressive therapy.
  • ||||||||||  Remicade (infliximab) / Mitsubishi Tanabe, J&J
    [VIRTUAL] ASSOCIATION BETWEEN SEROPOSITIVITY AND DISCONTINUATION OF INFLIXIMAB IN RHEUMATOID ARTHRITIS (Poster View) -  May 22, 2020 - Abstract #EULAR2020EULAR_3799;    
    RF and ACPA seropositivity was significantly predictive of discontinuation of infliximab therapy after adjusting for baseline characteristics, including age, sex, stage, class, disease activity at baseline, and prednisolone use ( Table 2 ). RF and ACPA seropositivity in bio-naïve patients with RA correlated with a higher rate of infliximab discontinuation due to adverse events or ineffectiveness.
  • ||||||||||  Actemra IV (tocilizumab) / Roche, JW Pharma
    [VIRTUAL] TREATMENT OF GIANT CELL ARTERITIS WITH TOCILIZUMAB IN CLINICAL PRACTICE IN SWEDEN (Poster View) -  May 22, 2020 - Abstract #EULAR2020EULAR_3575;    
    This study confirms a marked reduction in the use of oral prednisolone following treatment with TCZ, and demonstrates that in a majority of patients in clinical practice, treatment with TCZ for GCA is extended beyond one year. Future analyses will evaluate the association of these observed treatment patterns with the level of GCA disease control, co-morbidities and quality of life, over time.
  • ||||||||||  Orencia (abatacept) / BMS, Actemra IV (tocilizumab) / Roche, JW Pharma, Xeljanz (tofacitinib) / Pfizer, Marche Polytechnic University
    [VIRTUAL] EFFICACY OF JAK INHIBITORS IN REFRACTORY RHEUMATOID ARTHRITIS () -  May 22, 2020 - Abstract #EULAR2020EULAR_3239;    
    These findings, albeit retrospective, suggest that low concomitant PSL dose and long disease duration at the time of TOF therapy initiation were factors for TOF continuation. Therapy continuation rate was decreased in patients with refractory RA, and further study on switching therapy between different JAK inhibitors is anticipated.
  • ||||||||||  Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
    [VIRTUAL] FRACTURE RISK ASSESSMENT BY FRAX IN A SYSTEMIC LUPUS ERYTHEMATOSUS PORTUGUESE COHORT (Poster View) -  May 22, 2020 - Abstract #EULAR2020EULAR_3208;    
    However, we found no statistically significant difference in the estimated fracture risk with and without DXA. This, together with the good level of agreement between FRAX with and without DXA, suggests that the fracture risk estimation, even without DXA, may be an appropriate approach.
  • ||||||||||  cyclophosphamide intravenous / Generic mfg.
    [VIRTUAL] INTERSTITIAL PNEUMONIA WITH AUTOIMMUNE FEATURES (IPAF): A SINGLE CENTER, PROSPECTIVE STUDY () -  May 22, 2020 - Abstract #EULAR2020EULAR_3179;    
    A trend of improvement in PFTs and a significant risk of respiratory tract infections mainly in the first semester of treatment and in patients with non-UIP radiological pattern were observed. Larger prospective studies are warranted in order to elucidate IPAF’s prognosis and to identify effective management approaches.