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147 Diseases |  |
75 Trials |
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75 Trials |  |
10149 News |  |
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- Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
[VIRTUAL] Insulin Autoimmune Syndrome as a Rare Cause of Hypoglycemia () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_1084;
His medications included bisoprolol 2.5 mg daily...Prednisolone 30 mg daily was started with improvement and was tapered slowly after 16 weeks after mild hyperglycemia developed...Short-term treatment with steroids was effective in treating hypoglycaemia and careful follow-up is ongoing. If the patient recurs, rituximab will be employed.
- prednisolone / Generic mfg.
[VIRTUAL] Glucocorticoid- Induced Hyperglycemia, Higher Mortality and Morbidity? a Retrospective Analysis () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_1045;
Hypoglycemia was infrequent, but also associated with higher risk for adverse outcome. Future studies should evaluate whether glucose control with novel treatment modalities has a beneficial effect on clinical outcomes in patients with GC-induced hyperglycemia.
- prednisolone / Generic mfg.
[VIRTUAL] Steroid:Corticosteroid-Binding Globulin Interactions; Effects of Neutrophil Elastase Cleavage, Pyrexia and Acidosis () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_495;
Results A 4–8 fold reduction in affinity for cortisol, cortisone, corticosterone, 11-deoxycortisol, progesterone, 17-hydroxyprogesterone and prednisolone occurred with NE-mediated haCBG-to-laCBG conversion, cortisol expectedly displayed the highest binding affinity...Synergy of NE cleavage and pyrexia/acidosis may serve for local inflammatory site cortisol delivery and increase free cortisol. These findings demonstrate the modifiable hormone binding characteristics of CBG in (patho-)physiological conditions, supporting its significance in cortisol delivery in obviating systemic inflammation and multiorgan-organ failure in patients with septic shock and its association with mortality4.
- Synacthen Depot (cosyntropin) / Novartis, Mallinckrodt, Alliance, prednisolone / Generic mfg., hydrocortisone / Generic mfg.
[VIRTUAL] Evaluation of Adrenal Insufficiency and Recovery in Rheumatology Patients on Long-Term Glucocorticoid Therapy () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_443;
These data also suggest no significant difference in adrenal recovery if switched to hydrocortisone versus continuing on prednisolone. ACTH levels were not fully suppressed in patients with adrenal insufficiency and did not predict recovery.
- prednisolone / Generic mfg.
[VIRTUAL] Association Between Long-Term Prednisolone Induced Adrenal Insufficiency and Polymorphisms in the Glucocorticoid Receptor Gene () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_434;
However, the effect of prednisolone dose on stimulated cortisol depended on the GR SNPs: Cortisol was less suppressed with higher current prednisolone dose in patients carrying the insensitive SNPs. The substantially higher frequency of the Bcl1 SNP is remarkable even with modest n=239.
- prednisolone / Generic mfg.
[VIRTUAL] High Mortality Rate in Oral Glucocorticoid Users: A Case-Control Study () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_416;
Patients receiving ≥5 mg prednisolone (or equivalent dose of other GC) daily for ≥21 days between 2007-2014 were included...GC users have excess mortality compared to the background population. This illustrates the importance of surveillance for patients on oral GC treatment where adverse effects should be monitored and, when indicated, appropriately treated.
- Decadron (dexamethasone) / Merck (MSD)
[VIRTUAL] Giant Adrenal Myelolipoma Associated with Prolonged ACTH Elevation in a Patient with Congenital Adrenal Hyperplasia (CAH) () - Jun 20, 2020 - Abstract #ENDOI2020ENDO-I_376;
The role of ACTH in development of myelolipomas is supported by the increased incidence in patients with Addison’s disease, Nelson’s syndrome and ACTH dependent Cushing Disease. Our case supports the role of ACTH as the myelipoma developed after the reduction of patient’s glucocorticoid treatment and ACTH levels were high for years.
- || prednisolone / Generic mfg.
Clinical, Journal: Lupus enteritis as the sole presenting feature of systemic lupus erythematosus: case report and review of the literature. (Pubmed Central) - Jun 20, 2020
Even though lupus enteritis is rare, it can be the initial presentation of SLE. In young adolescent girls with recurrent abdominal pain, the possibility of lupus enteritis should be borne in mind.
- | prednisolone / Generic mfg., AmBisome (amphotericin b liposome) / Gilead, Grupo Biotoscana, Sumitomo Dainippon, Astellas
Journal: Cladophialophora bantiana infection mimicking neuromyelitis optica. (Pubmed Central) - Jun 19, 2020
C. bantiana infection should be considered in patients with myelitis presenting with longitudinal lesions and CNS abscess in an immunocompromised state.
- || prednisone / Generic mfg.
PK/PD data, Journal: Tear Fluid Pharmacokinetics Following Oral Prednisone Administration in Dogs With and Without Conjunctivitis. (Pubmed Central) - Jun 19, 2020
Based on drug PK in tears, oral prednisone is likely safe for the management of reflex uveitis and ocular surface diseases. However, further prospective trials using systemic corticotherapy in diseased animals are warranted to confirm findings from this preclinical study.
- | prednisolone / Generic mfg.
Journal: Magnesium and Calcium Reveal Different Chelating Effects in a Steroid Compound: A Model Study of Prednisolone Using NMR Spectroscopy. (Pubmed Central) - Jun 19, 2020
Additionally, using the continuous variation method, we deduced that the stoichiometric ratios of the Prd/Mg and Prd/Ca complexes were 1:1 and 2:1, respectively. All of the evidence led us to conclude that the Prd/Mg and Prd/Ca complexes are mediated by different chelating mechanisms.
- | Actemra IV (tocilizumab) / Roche, JW Pharma, Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Journal: Successful combined treatment with thymectomy, rituximab and tocilizumab for severe thymoma-associated multi autoimmune syndrome. (Pubmed Central) - Jun 19, 2020
TAMA is associated with a spectrum of autoantibodies and immune-mediated damage to multiple organs. Even if thymectomy is crucial for long term prognosis, aggressive immunomodulation should be considered early in the disease course, especially in cases showing involvement of the peripheral and/or central nervous system.
- | Remicade (infliximab) / Mitsubishi Tanabe, J&J, Humira (adalimumab) / Eisai, AbbVie
Journal: Long-Term Outcomes of Treatment with Biological Agents in Eyes with Refractory, Active, Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis. (Pubmed Central) - Jun 19, 2020
Overall, eyes treated with biologic agents after failure of treatment with corticosteroids and a second-line immunosuppression drug experienced satisfactory disease control (87.2%), reduced use of systemic immunosuppression, stable visual acuity, and a 23.7% risk of disease relapse. After multivariate adjustment, older age, treatment with adalimumab (versus infliximab), and inactive concomitant systemic disease were associated with a lower risk of treatment failure.
- || prednisolone / Generic mfg., Thalomid (thalidomide) / Fujimoto, BMS
Clinical, Journal: Vocal cord involvement and hoarseness in a patient with Behcets disease: A rare case report. (Pubmed Central) - Jun 19, 2020
Behcets disease can cause damage to multiple organs. Although the combination of vocal cord ulcers and hoarseness is rare in patients with BD and has not been previously reported to date, such patients should be treated with caution in clinical practice.
- | prednisolone / Generic mfg., levocetirizine / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date, HEOR, Cost-analysis: Efficacy and Cost Analysis of Steroids in Treatment of Otitis Media With Effusion (clinicaltrials.gov) - Jun 19, 2020
P4, N=160, Completed, Sponsor: Lumbini Medical College
Although the combination of vocal cord ulcers and hoarseness is rare in patients with BD and has not been previously reported to date, such patients should be treated with caution in clinical practice. Not yet recruiting --> Completed | Trial completion date: Sep 2019 --> Mar 2020 | Trial primary completion date: Jul 2019 --> Feb 2020
- ||| prednisolone / Generic mfg., Zytiga (abiraterone acetate) / J&J, Xofigo (radium Ra-223 dichloride) / Bayer
Clinical, P3 data, Journal: Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a randomised, double-blind, placebo-controlled, phase 3 trial. (Pubmed Central) - Jun 18, 2020
P3
The addition of radium-223 to abiraterone acetate plus prednisone or prednisolone did not improve symptomatic skeletal event-free survival in patients with castration-resistant prostate cancer and bone metastases, and was associated with an increased frequency of bone fractures compared with placebo. Thus, we do not recommend use of this combination.
- ||| bortezomib / Generic mfg., doxorubicin hydrochloride / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, P3 data, Journal, IO Biomarker: Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial. (Pubmed Central) - Jun 18, 2020
P3
This is the first large-scale study in diffuse large B-cell lymphoma to use real-time molecular characterisation for prospective stratification, randomisation, and subsequent analysis of biologically distinct subgroups of patients. The addition of bortezomib did not improve progression-free survival.
- || Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo, Zevalin (ibritumomab tiuxetan) / Spectrum, Servier, Mundipharma
Clinical, P2 data, Journal: Rituximab-PECC induction followed by Y-ibritumomab tiuxetan consolidation in relapsed or refractory DLBCL patients who are ineligible for or have failed ASCT: results from a phase II HOVON study. (Pubmed Central) - Jun 18, 2020
In conclusion, for relapsed DLBCL patients the largely oral R-PECC regimen achieves promising response rates, combined with an acceptable safety profile. Consolidation with Y-ibritumomab tiuxetan resulted in long-term response durations in approximately one third of the patients that received it.
- | prednisolone / Generic mfg.
Journal: Adrenal insufficiency due to recurrent renal cell carcinoma in the left adrenal gland 3 years after right radical nephrectomy for renal cell carcinoma. (Pubmed Central) - Jun 18, 2020
The symptoms improved after prednisolone replacement. The case reminds clinicians the diagnosis of primary adrenal insufficiency due to tumor metastasis should be considered in patients with non-specific gastrointestinal symptoms.
- || Opdivo (nivolumab) / Ono Pharma, BMS
Clinical, Journal: Nivolumab-induced IgA nephropathy in a patient with advanced gastric cancer: A case report. (Pubmed Central) - Jun 18, 2020
After drug discontinuation, nivolumab-induced IgA nephropathy is likely to respond to moderate doses of steroid therapy with early tapering. However, more evidence is needed to determine whether nivolumab can be safely restarted during or after steroid therapy.
- ||| Clinical: Mortality was high- 41% in intubated group, with 35% reduction in dexamethasone group (95% CI 12% - 52%), which gets to about 27%. I got NNT of 7, they say 8, but either way- low. Protocol also allowed substitution with prednisolone or hydrocortisone for pregnancy (Twitter) - Jun 17, 2020
- | ibuprofen / Generic mfg.
Journal: Double and adiabatic BANGO for concatenating two NMR experiments relying on the same pool of magnetization. (Pubmed Central) - Jun 17, 2020
It is shown how the same pool of magnetization can be tapped twice in two different concatenations of three experiments into a single pulse sequence with only one relaxation delay. This is accomplished by using the BANGO pulse sequence element twice for independent rotations of H magnetization attached or not attached to C and it includes a refinement of BANGO with an adiabatic C inversion pulse resulting in improved tolerance to a spread in J coupling constants that translates directly into improved sensitivity of the modular experiment relying on H magnetization attached to C. The two new pulse sequences are SEA XLOC-HMBC-H2OBC/2BOB and SEA XLOC(ZQ)-SEA XLOC(2Q)-H2OBC/2BOB which both represent a rapid route to complete heteronuclear one-bond and long-range J correlation maps for small molecules, as is demonstrated on ibuprofen and prednisolone.
- |||| prednisolone / Generic mfg.
Clinical: DEX acutely reduces PLT aggregation. Prednisolone has better efficacy in this regard. Plausible that in a floridly immuno-thrombotic severe case, inhibitor of PLT aggregation would help. Also explains why EARLY DEX can be harmful. Initial (not haywire) thrombosis is protective. (Twitter) - Jun 16, 2020
- ||| Clinical: Also important that although 6mg of #dexamethasone is the #glucocorticoid mentioned in the release and in the protocol initially, doctors could give equivalent doses of other #steroids: 40mg of #prednisolone, 80mg of #hydrocortisone, others For all was up to 10 day intervention (Twitter) - Jun 16, 2020
- |||| prednisolone / Generic mfg.
The benefit occurs in the subset that will go to feed-forward immuno-thrombosis (aka “severe”), expected to benefit from reducing platelet aggregation in ANY shape or form, including DEX or better yet prednisolone, AC, anti-platelets and I hypothesize 5-HT antagonists. (Twitter) - Jun 16, 2020
- || prednisolone / Generic mfg.
Wary of paradoxical reduced effect on platelet aggregation with higher doses of DEX. https://t.co/07rcFEFF0q Prednisolone more uniformly effective to reduce platelet aggregation? https://t.co/soaJeB0fpb https://t.co/1ygeJLRjZw (Twitter) - Jun 16, 2020
- ||| dexamethasone / Generic mfg., Decadron (dexamethasone) / Merck (MSD), prednisolone / Generic mfg.
If the dexamethasone regimens you myeloma docs use get a lowercase d, eg RVd or KRd, I think this COVID dose (6 mg/d x 10 days of dex or the equivalent of prednisolone) should be a superscript or subscript d - or at least a smaller font 😉 (Twitter) - Jun 16, 2020
- || Decadron (dexamethasone) / Merck (MSD), prednisone / Generic mfg., Zytiga (abiraterone acetate) / J&J
Review, Journal: Corticosteroid switch after progression on abiraterone acetate plus prednisone. (Pubmed Central) - Jun 14, 2020
This is accomplished by using the BANGO pulse sequence element twice for independent rotations of H magnetization attached or not attached to C and it includes a refinement of BANGO with an adiabatic C inversion pulse resulting in improved tolerance to a spread in J coupling constants that translates directly into improved sensitivity of the modular experiment relying on H magnetization attached to C. The two new pulse sequences are SEA XLOC-HMBC-H2OBC/2BOB and SEA XLOC(ZQ)-SEA XLOC(2Q)-H2OBC/2BOB which both represent a rapid route to complete heteronuclear one-bond and long-range J correlation maps for small molecules, as is demonstrated on ibuprofen and prednisolone. Although large randomized prospective trials are warranted, steroid switch seems to offer a good option for certain patients treated with abiraterone acetate plus prednisone or prednisolone.
- prednisolone / Generic mfg., tacrolimus / Generic mfg.
[VIRTUAL] TACROLIMUS PLUS LOW DOSE PREDNISOLONE THERAPY IS MORE EFFECTIVE IN PLA2R -VE MEMBRANOUS NEPHROPATHY PATIENTS () - Jun 13, 2020 - Abstract #ERAEDTA2020ERA-EDTA_844;
- Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
[VIRTUAL] THE EFFECTS OF RITUXIMAB MAINTENANCE THERAPY ON LUPUS NEPHRITIS () - Jun 13, 2020 - Abstract #ERAEDTA2020ERA-EDTA_808;
RTX is confirmed as an effective option for patients with LN. A RMT may have a role in improving LN disease control compared to a single RTX administration.
- || doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, Journal: Stand-alone intrathecal central nervous system (CNS) prophylaxis provide unclear benefit in reducing CNS relapse risk in elderly DLBCL patients treated with R-CHOP and is associated increased infection-related toxicity. (Pubmed Central) - Jun 12, 2020
Many patients aged ≥70 years are unsuitable for high-dose methotrexate (HDMTX) prophylaxis and therefore often receive stand-alone intrathecal prophylaxis...CNS-IPI is valid in elderly R-CHOP-treated DLBCL patients, with the highest risk in those with CNS-IPI 6 and R/A involvement. We observed no clear benefit for stand-alone intrathecal prophylaxis but observed an independent increased risk of infection-related admission during R-CHOP when intrathecal prophylaxis was administered.
- | doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Journal: Outcomes of synchronous systemic and central nervous system (CNS) involvement of diffuse large B-cell lymphoma are dictated by the CNS disease: a collaborative study of the Australasian Lymphoma Alliance. (Pubmed Central) - Jun 12, 2020
Hyperfractionated or infusional systemic treatment did not improve survival compared to R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone) (2-year OS 49% for both groups). Our study suggests that adequate control of the CNS disease is paramount and is best achieved by intensive CNS-directed induction.
- || prednisolone / Generic mfg.
Retrospective data, Review, Journal: High-dose Corticosteroids for Adult Bell's Palsy: Systematic Review and Meta-analysis. (Pubmed Central) - Jun 12, 2020
High-dose corticosteroids reduce nonrecovery in patients with Bell's palsy. The dose of high-dose corticosteroids was varied and further prospective study is needed to identify an adequate dose of corticosteroids in these patients.
- | tacrolimus / Generic mfg.
Retrospective data, Journal: Post-transplant diabetes mellitus associated with heart and lung transplant. (Pubmed Central) - Jun 12, 2020
The majority of the patients were screened before and after transplant for glucose abnormality. The authors recommend that all patients should be managed in a multidisciplinary setting including transplant physicians, endocrinlogist, diabetes nurse specialists, transplant nurses and dietitians.
- || ibuprofen / Generic mfg.
Review, Journal: Acupuncture and related interventions for carpal tunnel syndrome: systematic review. (Pubmed Central) - Jun 11, 2020
For both symptom relief and function improvement, manual acupuncture is superior to ibuprofen while electroacupuncture plus splinting outperforms splinting alone. Limited evidence showed electroacupuncture's potential role in pain reduction.
- | tacrolimus / Generic mfg.
Retrospective data, Journal: RETROSPECTIVE EVALUATION OF ANESTHETIC TECHNIQUES IN PREGNANT WOMEN WITH RENAL TRANSPLANTATION. (Pubmed Central) - Jun 11, 2020
The mean weight of the newborns was determined as 2707.3±501.5 g. While the number of newborns with a low birth weight (<2500gr) was 18 (38%), of these, 3 (0.6%) were below 2000 g. It was found that 36.2% (n=17) of the newborns required intensive care. None of the patients developed graft rejection.
- || Actemra IV (tocilizumab) / Roche, JW Pharma
Clinical, Journal: A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. (Pubmed Central) - Jun 11, 2020
P2
The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.
- ||| Xofigo (radium Ra-223 dichloride) / Bayer
Trial completion date: ERA 223: Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms (clinicaltrials.gov) - Jun 11, 2020
P3, N=806, Active, not recruiting, Sponsor: Bayer
In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. Trial completion date: Jun 2020 --> Dec 2020
- ||| Clinical, P3 data, Journal: Re: Addition of Radium-223 to Abiraterone Acetate and Prednisone or Prednisolone in Patients with Castration-resistant Prostate Cancer and Bone Metastases (ERA 223): A Randomised, Double-blind, Placebo-controlled, Phase 3 Trial. (Pubmed Central) - Jun 10, 2020
Trial completion date: Jun 2020 --> Dec 2020 No abstract available
- ||| Journal, Adverse events: Pharmacovigilance Assessment of Drug-Induced Acute Pancreatitis Using a Spontaneous Reporting Database. (Pubmed Central) - Jun 10, 2020
Most of the identified drugs were already known to induce AP, but the likelihood of the reporting of AP varied among the drugs. Our results should raise physicians' awareness of drugs associated with AP, but further investigation of these medications is warranted.
- || doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, P2 data, Journal: Multicenter Phase 2 Study of Reduced-Dose CHOP Chemotherapy Combined With Rituximab for Elderly Patients With Diffuse Large B-Cell Lymphoma. (Pubmed Central) - Jun 8, 2020
Outcomes of RD-R-CHOP chemotherapy were comparable to those of standard-dose R-CHOP or previous dose-adjusted R-CHOP chemotherapy. In the future, strategies such as tailored therapy based on geriatric assessment results are needed to determine the chemotherapeutic dosage.
- | doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Journal: Primary pancreatic diffuse large B-cell lymphoma diagnosed by endoscopic ultrasound guided FNAC: A rare entity. (Pubmed Central) - Jun 8, 2020
The patient was started on rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (RCHOP) regimen. EUS guided FNA along with ROSE, cell bock, and immunocytochemistry helps in the diagnosis of primary pancreatic lymphoma.
- | prednisolone / Generic mfg.
Journal: Prednisolone vs dexamethsone in croup. (Pubmed Central) - Jun 8, 2020
EUS guided FNA along with ROSE, cell bock, and immunocytochemistry helps in the diagnosis of primary pancreatic lymphoma. No abstract available
- || prednisolone / Generic mfg.
Clinical, Journal: Inflammatory myofibroblastic tumor of maxillary sinus successfully treated with radiotherapy and corticosteroid: report of a rare case. (Pubmed Central) - Jun 7, 2020
No abstract available This is the first report where such magnificent response was attained in primary setting treated with RT and steroids as opposed to surgery which used to be considered as standard of care till now.
- | prednisolone / Generic mfg., valacyclovir / Generic mfg., acyclovir / Generic mfg.
Journal: Descemet Membrane Endothelial Keratoplasty in Irreversible Corneal Edema Due to Herpes Simplex Virus Endotheliitis. (Pubmed Central) - Jun 4, 2020
The postoperative course may be complicated by HSV recurrence. Prophylactic oral antivirals for 1 year or more and topical antivirals are useful for the prevention of recurrence.
- | prednisolone / Generic mfg., Vexol (rimexolone ophthalmic) / Novartis
Journal: Long-term Outcomes on de novo Ocular Hypertensive Response to Topical Corticosteroids After Corneal Transplantation. (Pubmed Central) - Jun 4, 2020
Prophylactic oral antivirals for 1 year or more and topical antivirals are useful for the prevention of recurrence. The use of alternate topical corticosteroids may be considered in cases of steroid-induced ocular hypertension after PKP because they offer good antiinflammatory prophylaxis with reduced hypertensive response.
- | bromfenac ophthalmic solution / Generic mfg.
Journal: Incidence of cystoid macular edema following routine cataract surgery using NSAIDs alone or with corticosteroids. (Pubmed Central) - Jun 4, 2020
Post-cataract surgery cystoid macular edema developed less frequently following topical non-steroidal anti-inflammatory drugs regimen compared to the other therapies evaluated. Bromfenac, without corticosteroids, achieved lower rates of cystoid macular edema vs. various combinations of non-ste-roidal anti-inflammatory drugs with corticosteroids.
- | hydroxychloroquine / Generic mfg.
Journal: Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction. (Pubmed Central) - Jun 4, 2020
We believe that the reaction seen in our patient was a secondary change to pathological alteration due to SLE. However, as yet unrecognized factors may play a role in the development of a xanthomatous reaction in DLE.
- || prednisolone / Generic mfg.
Review, Journal: Empirical Treatment and Prevention of COVID-19. (Pubmed Central) - Jun 3, 2020
A proper combination of antiviral agents, immune modulators such as prednisolone, and anticoagulants such as heparin and anti-C5a antagonists could be employed to minimize lung damage and prevent systemic involvements. Finally, strategies to achieve population immunity against SARS-CoV-2 should be developed through understanding of the interaction between the immune system and the virus.
- | prednisolone / Generic mfg.
Journal: Continuous rhPTH (1-34) treatment in chronic hypoparathyroidism. (Pubmed Central) - Jun 3, 2020
Standard treatment of hypoparathyroidism still consists of administration of calcium and active vitamin D. Very few patients with hypoparathyroidism also do not respond sufficiently to standard treatment or administration of s.c. parathyroid hormone once or twice daily. In those cases, continuous s.c. administration of parathyroid hormone via insulin pump may represent a successful treatment alternative.