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153 Diseases |  |
74 Trials |
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74 Trials |  |
10107 News |  |
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- | prednisolone / Generic mfg.
Journal: Adrenal insufficiency due to recurrent renal cell carcinoma in the left adrenal gland 3 years after right radical nephrectomy for renal cell carcinoma. (Pubmed Central) - Jun 18, 2020
The symptoms improved after prednisolone replacement. The case reminds clinicians the diagnosis of primary adrenal insufficiency due to tumor metastasis should be considered in patients with non-specific gastrointestinal symptoms.
- || Opdivo (nivolumab) / Ono Pharma, BMS
Clinical, Journal: Nivolumab-induced IgA nephropathy in a patient with advanced gastric cancer: A case report. (Pubmed Central) - Jun 18, 2020
After drug discontinuation, nivolumab-induced IgA nephropathy is likely to respond to moderate doses of steroid therapy with early tapering. However, more evidence is needed to determine whether nivolumab can be safely restarted during or after steroid therapy.
- ||| Clinical: Mortality was high- 41% in intubated group, with 35% reduction in dexamethasone group (95% CI 12% - 52%), which gets to about 27%. I got NNT of 7, they say 8, but either way- low. Protocol also allowed substitution with prednisolone or hydrocortisone for pregnancy (Twitter) - Jun 17, 2020
- | ibuprofen / Generic mfg.
Journal: Double and adiabatic BANGO for concatenating two NMR experiments relying on the same pool of magnetization. (Pubmed Central) - Jun 17, 2020
It is shown how the same pool of magnetization can be tapped twice in two different concatenations of three experiments into a single pulse sequence with only one relaxation delay. This is accomplished by using the BANGO pulse sequence element twice for independent rotations of H magnetization attached or not attached to C and it includes a refinement of BANGO with an adiabatic C inversion pulse resulting in improved tolerance to a spread in J coupling constants that translates directly into improved sensitivity of the modular experiment relying on H magnetization attached to C. The two new pulse sequences are SEA XLOC-HMBC-H2OBC/2BOB and SEA XLOC(ZQ)-SEA XLOC(2Q)-H2OBC/2BOB which both represent a rapid route to complete heteronuclear one-bond and long-range J correlation maps for small molecules, as is demonstrated on ibuprofen and prednisolone.
- |||| prednisolone / Generic mfg.
Clinical: DEX acutely reduces PLT aggregation. Prednisolone has better efficacy in this regard. Plausible that in a floridly immuno-thrombotic severe case, inhibitor of PLT aggregation would help. Also explains why EARLY DEX can be harmful. Initial (not haywire) thrombosis is protective. (Twitter) - Jun 16, 2020
- ||| Clinical: Also important that although 6mg of #dexamethasone is the #glucocorticoid mentioned in the release and in the protocol initially, doctors could give equivalent doses of other #steroids: 40mg of #prednisolone, 80mg of #hydrocortisone, others For all was up to 10 day intervention (Twitter) - Jun 16, 2020
- |||| prednisolone / Generic mfg.
The benefit occurs in the subset that will go to feed-forward immuno-thrombosis (aka “severe”), expected to benefit from reducing platelet aggregation in ANY shape or form, including DEX or better yet prednisolone, AC, anti-platelets and I hypothesize 5-HT antagonists. (Twitter) - Jun 16, 2020
- || prednisolone / Generic mfg.
Wary of paradoxical reduced effect on platelet aggregation with higher doses of DEX. https://t.co/07rcFEFF0q Prednisolone more uniformly effective to reduce platelet aggregation? https://t.co/soaJeB0fpb https://t.co/1ygeJLRjZw (Twitter) - Jun 16, 2020
- ||| dexamethasone / Generic mfg., Decadron (dexamethasone) / Merck (MSD), prednisolone / Generic mfg.
If the dexamethasone regimens you myeloma docs use get a lowercase d, eg RVd or KRd, I think this COVID dose (6 mg/d x 10 days of dex or the equivalent of prednisolone) should be a superscript or subscript d - or at least a smaller font 😉 (Twitter) - Jun 16, 2020
- || Decadron (dexamethasone) / Merck (MSD), prednisone / Generic mfg., Zytiga (abiraterone acetate) / J&J
Review, Journal: Corticosteroid switch after progression on abiraterone acetate plus prednisone. (Pubmed Central) - Jun 14, 2020
This is accomplished by using the BANGO pulse sequence element twice for independent rotations of H magnetization attached or not attached to C and it includes a refinement of BANGO with an adiabatic C inversion pulse resulting in improved tolerance to a spread in J coupling constants that translates directly into improved sensitivity of the modular experiment relying on H magnetization attached to C. The two new pulse sequences are SEA XLOC-HMBC-H2OBC/2BOB and SEA XLOC(ZQ)-SEA XLOC(2Q)-H2OBC/2BOB which both represent a rapid route to complete heteronuclear one-bond and long-range J correlation maps for small molecules, as is demonstrated on ibuprofen and prednisolone. Although large randomized prospective trials are warranted, steroid switch seems to offer a good option for certain patients treated with abiraterone acetate plus prednisone or prednisolone.
- prednisolone / Generic mfg., tacrolimus / Generic mfg.
[VIRTUAL] TACROLIMUS PLUS LOW DOSE PREDNISOLONE THERAPY IS MORE EFFECTIVE IN PLA2R -VE MEMBRANOUS NEPHROPATHY PATIENTS () - Jun 13, 2020 - Abstract #ERAEDTA2020ERA-EDTA_844;
- Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
[VIRTUAL] THE EFFECTS OF RITUXIMAB MAINTENANCE THERAPY ON LUPUS NEPHRITIS () - Jun 13, 2020 - Abstract #ERAEDTA2020ERA-EDTA_808;
RTX is confirmed as an effective option for patients with LN. A RMT may have a role in improving LN disease control compared to a single RTX administration.
- || doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, Journal: Stand-alone intrathecal central nervous system (CNS) prophylaxis provide unclear benefit in reducing CNS relapse risk in elderly DLBCL patients treated with R-CHOP and is associated increased infection-related toxicity. (Pubmed Central) - Jun 12, 2020
Many patients aged ≥70 years are unsuitable for high-dose methotrexate (HDMTX) prophylaxis and therefore often receive stand-alone intrathecal prophylaxis...CNS-IPI is valid in elderly R-CHOP-treated DLBCL patients, with the highest risk in those with CNS-IPI 6 and R/A involvement. We observed no clear benefit for stand-alone intrathecal prophylaxis but observed an independent increased risk of infection-related admission during R-CHOP when intrathecal prophylaxis was administered.
- | doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Journal: Outcomes of synchronous systemic and central nervous system (CNS) involvement of diffuse large B-cell lymphoma are dictated by the CNS disease: a collaborative study of the Australasian Lymphoma Alliance. (Pubmed Central) - Jun 12, 2020
Hyperfractionated or infusional systemic treatment did not improve survival compared to R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone) (2-year OS 49% for both groups). Our study suggests that adequate control of the CNS disease is paramount and is best achieved by intensive CNS-directed induction.
- || prednisolone / Generic mfg.
Retrospective data, Review, Journal: High-dose Corticosteroids for Adult Bell's Palsy: Systematic Review and Meta-analysis. (Pubmed Central) - Jun 12, 2020
High-dose corticosteroids reduce nonrecovery in patients with Bell's palsy. The dose of high-dose corticosteroids was varied and further prospective study is needed to identify an adequate dose of corticosteroids in these patients.
- | tacrolimus / Generic mfg.
Retrospective data, Journal: Post-transplant diabetes mellitus associated with heart and lung transplant. (Pubmed Central) - Jun 12, 2020
The majority of the patients were screened before and after transplant for glucose abnormality. The authors recommend that all patients should be managed in a multidisciplinary setting including transplant physicians, endocrinlogist, diabetes nurse specialists, transplant nurses and dietitians.
- || ibuprofen / Generic mfg.
Review, Journal: Acupuncture and related interventions for carpal tunnel syndrome: systematic review. (Pubmed Central) - Jun 11, 2020
For both symptom relief and function improvement, manual acupuncture is superior to ibuprofen while electroacupuncture plus splinting outperforms splinting alone. Limited evidence showed electroacupuncture's potential role in pain reduction.
- | tacrolimus / Generic mfg.
Retrospective data, Journal: RETROSPECTIVE EVALUATION OF ANESTHETIC TECHNIQUES IN PREGNANT WOMEN WITH RENAL TRANSPLANTATION. (Pubmed Central) - Jun 11, 2020
The mean weight of the newborns was determined as 2707.3±501.5 g. While the number of newborns with a low birth weight (<2500gr) was 18 (38%), of these, 3 (0.6%) were below 2000 g. It was found that 36.2% (n=17) of the newborns required intensive care. None of the patients developed graft rejection.
- || Actemra IV (tocilizumab) / Roche, JW Pharma
Clinical, Journal: A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. (Pubmed Central) - Jun 11, 2020
P2
The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.
- ||| Xofigo (radium Ra-223 dichloride) / Bayer
Trial completion date: ERA 223: Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms (clinicaltrials.gov) - Jun 11, 2020
P3, N=806, Active, not recruiting, Sponsor: Bayer
In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. Trial completion date: Jun 2020 --> Dec 2020
- ||| Clinical, P3 data, Journal: Re: Addition of Radium-223 to Abiraterone Acetate and Prednisone or Prednisolone in Patients with Castration-resistant Prostate Cancer and Bone Metastases (ERA 223): A Randomised, Double-blind, Placebo-controlled, Phase 3 Trial. (Pubmed Central) - Jun 10, 2020
Trial completion date: Jun 2020 --> Dec 2020 No abstract available
- ||| Journal, Adverse events: Pharmacovigilance Assessment of Drug-Induced Acute Pancreatitis Using a Spontaneous Reporting Database. (Pubmed Central) - Jun 10, 2020
Most of the identified drugs were already known to induce AP, but the likelihood of the reporting of AP varied among the drugs. Our results should raise physicians' awareness of drugs associated with AP, but further investigation of these medications is warranted.
- || doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, P2 data, Journal: Multicenter Phase 2 Study of Reduced-Dose CHOP Chemotherapy Combined With Rituximab for Elderly Patients With Diffuse Large B-Cell Lymphoma. (Pubmed Central) - Jun 8, 2020
Outcomes of RD-R-CHOP chemotherapy were comparable to those of standard-dose R-CHOP or previous dose-adjusted R-CHOP chemotherapy. In the future, strategies such as tailored therapy based on geriatric assessment results are needed to determine the chemotherapeutic dosage.
- | doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Journal: Primary pancreatic diffuse large B-cell lymphoma diagnosed by endoscopic ultrasound guided FNAC: A rare entity. (Pubmed Central) - Jun 8, 2020
The patient was started on rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (RCHOP) regimen. EUS guided FNA along with ROSE, cell bock, and immunocytochemistry helps in the diagnosis of primary pancreatic lymphoma.
- | prednisolone / Generic mfg.
Journal: Prednisolone vs dexamethsone in croup. (Pubmed Central) - Jun 8, 2020
EUS guided FNA along with ROSE, cell bock, and immunocytochemistry helps in the diagnosis of primary pancreatic lymphoma. No abstract available
- || prednisolone / Generic mfg.
Clinical, Journal: Inflammatory myofibroblastic tumor of maxillary sinus successfully treated with radiotherapy and corticosteroid: report of a rare case. (Pubmed Central) - Jun 7, 2020
No abstract available This is the first report where such magnificent response was attained in primary setting treated with RT and steroids as opposed to surgery which used to be considered as standard of care till now.
- | prednisolone / Generic mfg., valacyclovir / Generic mfg., acyclovir / Generic mfg.
Journal: Descemet Membrane Endothelial Keratoplasty in Irreversible Corneal Edema Due to Herpes Simplex Virus Endotheliitis. (Pubmed Central) - Jun 4, 2020
The postoperative course may be complicated by HSV recurrence. Prophylactic oral antivirals for 1 year or more and topical antivirals are useful for the prevention of recurrence.
- | prednisolone / Generic mfg., Vexol (rimexolone ophthalmic) / Novartis
Journal: Long-term Outcomes on de novo Ocular Hypertensive Response to Topical Corticosteroids After Corneal Transplantation. (Pubmed Central) - Jun 4, 2020
Prophylactic oral antivirals for 1 year or more and topical antivirals are useful for the prevention of recurrence. The use of alternate topical corticosteroids may be considered in cases of steroid-induced ocular hypertension after PKP because they offer good antiinflammatory prophylaxis with reduced hypertensive response.
- | bromfenac ophthalmic solution / Generic mfg.
Journal: Incidence of cystoid macular edema following routine cataract surgery using NSAIDs alone or with corticosteroids. (Pubmed Central) - Jun 4, 2020
Post-cataract surgery cystoid macular edema developed less frequently following topical non-steroidal anti-inflammatory drugs regimen compared to the other therapies evaluated. Bromfenac, without corticosteroids, achieved lower rates of cystoid macular edema vs. various combinations of non-ste-roidal anti-inflammatory drugs with corticosteroids.
- | hydroxychloroquine / Generic mfg.
Journal: Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction. (Pubmed Central) - Jun 4, 2020
We believe that the reaction seen in our patient was a secondary change to pathological alteration due to SLE. However, as yet unrecognized factors may play a role in the development of a xanthomatous reaction in DLE.
- || prednisolone / Generic mfg.
Review, Journal: Empirical Treatment and Prevention of COVID-19. (Pubmed Central) - Jun 3, 2020
A proper combination of antiviral agents, immune modulators such as prednisolone, and anticoagulants such as heparin and anti-C5a antagonists could be employed to minimize lung damage and prevent systemic involvements. Finally, strategies to achieve population immunity against SARS-CoV-2 should be developed through understanding of the interaction between the immune system and the virus.
- | prednisolone / Generic mfg.
Journal: Continuous rhPTH (1-34) treatment in chronic hypoparathyroidism. (Pubmed Central) - Jun 3, 2020
Standard treatment of hypoparathyroidism still consists of administration of calcium and active vitamin D. Very few patients with hypoparathyroidism also do not respond sufficiently to standard treatment or administration of s.c. parathyroid hormone once or twice daily. In those cases, continuous s.c. administration of parathyroid hormone via insulin pump may represent a successful treatment alternative.
- || Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, Journal: Type B insulin resistance syndrome in a patient with type 1 diabetes. (Pubmed Central) - Jun 3, 2020
After a 4-month remission on low maintenance dose prednisolone, the patient relapsed, which required repeated plasmaphereses with temporarily remarkable effect. TBIRS should be considered in diabetic patients whose glycemia and/or insulin requirements are inexplicably and dramatically increased.
- || prednisolone / Generic mfg.
Clinical, Journal: Concomitant aortic valve replacement, mitral valve replacement, and coronary artery bypass grafting for aortic stenosis and mitral regurgitation in a patient with relapsing polychondritis. (Pubmed Central) - May 31, 2020
A 71-year-old female with relapsing polychondritis on prednisolone (5 mg/day) for 15 years presented at our hospital for further evaluation of valvular disease...We removed the tissue and performed bypass grafting to the right coronary artery. Postoperative recovery was uneventful, and she was discharged 27 days after surgery.
- || prednisolone / Generic mfg., methotrexate / Generic mfg., Ilaris (canakinumab) / Novartis
Clinical, Journal: The Long-Term Efficacy of Cochlear Implantation for Hearing Loss in Muckel-Wells Syndrome. (Pubmed Central) - May 31, 2020
Owing to successful cochlear implant surgery, she reacquired the hearing and communication function while being able to understand over 90% of monosyllables and words in the sound field of her daily life at 65 dB SPL for the next 13 years of her life. This suggests that peripheral cochlear damage induced by chronic inflammation contributes to the sensorineural hearing loss in cases with MWS, and that cochlear implantation can provide long-term hearing efficacy for patients with MWS with irreversible profound hearing loss.
- prednisolone / Generic mfg.
[VIRTUAL] Risk of hepatitis flare in inflammatory bowel disease patients with previous hepatitis B virus exposure - results from a territory-wide Hong Kong ibd registry study (Poster Area) - May 30, 2020 - Abstract #EASLILCI2020EASL-ILC-I-1284;
Use of thiopurine and ever exposure to steroid were risk factors for hepatitis flare. Use of biologic was not associated with risk of hepatitis flare.
- Benlysta (belimumab) / GSK
[VIRTUAL] Belimumab: a promising third line treatment option for refractory autoimmune hepatitis (Poster Area) - May 30, 2020 - Abstract #EASLILCI2020EASL-ILC-I-1072;
Belimumab could be an effective and safe third line treatment option for patients with refractory AIH and advanced liver fibrosis. However, long-term randomized control trials are needed in order to assess belimumab efficacy and safety in this difficult to treat subgroup of AIH patients.
- prednisolone / Generic mfg.
[VIRTUAL] In alcoholic hepatitis, cytokeratin 18 serum fragments reflect its severity and predict responsiveness to prednisolone (Poster Area) - May 30, 2020 - Abstract #EASLILCI2020EASL-ILC-I-473;
In patients with sAH serum CK18 fragments are strongly correlated with its severity and 90-day mortality. A cut-off of CK18-M30 >5000 IU/L appears to define a population of patients with severe inflammation in whom a beneficial response to prednisolone is seen at 90 days.
- | Copegus (ribavirin) / Bausch Health
Journal: An Exclusively Oral Ribavirin Regimen for Respiratory Syncytial Virus Infection after Lung Transplantation is Effective and Cost-Efficient. (Pubmed Central) - May 30, 2020
An exclusively oral regimen of loading and maintenance dose ribavirin for treatment of RSV post LTx appears to be effective and well-tolerated. Furthermore, it carries a significant cost saving and completely avoids hospital admission in 69% of patient episodes.
- tacrolimus / Generic mfg.
[VIRTUAL] Rabbit Anti-Thymocyte Globulin versus Anti-T Lymphocyte Globulin Rescue Therapies in Delayed Graft Function after Kidney Transplantation from Donors after Cardiac Death (Virtual) - May 29, 2020 - Abstract #ATC2020ATC_1178;
Our results suggest that DCD kidney recipients without induction therapy should accept rescue therapy for DGF. Compared with ATG-F, Thymoglobulin cannot shorten the duration of DGF, but can reduce acute rejection rate and did not increased infectious complications.
- tacrolimus / Generic mfg.
[VIRTUAL] Solid Organ Transplant Recipients with Pneumonia in Intensive Care UnıT: A Single Center Study (Virtual) - May 29, 2020 - Abstract #ATC2020ATC_794;
SOT recipients admitted to ICU with pneumonia are associated with poor prognosis. Most of the pneumonia episodes were seen 6 months after transplantation with high APACHE II scores predicting mortality.
- || Decadron (dexamethasone) / Merck (MSD)
Clinical, Journal: Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology. (Pubmed Central) - May 29, 2020
In severe cases like our subject, we posit that endolymphatic hydrops or hair cell loss may cause irreversible and asymmetrical deafness. Steroid prophylaxis via transtympanic application is debatable.
- | prednisolone / Generic mfg.
Journal: Effects of glucocorticoids on vitamin D-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts. (Pubmed Central) - May 29, 2020
Several glucocorticoids, including prednisolone, down regulated CYP24A1 mRNA and CYP24A1-mediated 24-hydroxylase activity in both Saos-2 and primary human osteoblasts...The experiments indicate formation of 11-deoxycortisol, a steroid with glucocorticoid activity, which can bind the glucocorticoid receptor. Our data showing suppression by glucocorticoids on CYP24A1 expression in human osteoblasts suggest a previously unknown mechanism for effects of glucocorticoids in human bone, where these compounds may interfere with regulation of active vitamin D levels.
- || prednisolone / Generic mfg., methotrexate / Generic mfg., leflunomide / Generic mfg.
Clinical, Journal: Association of cytokine patterns and clinical/laboratory parameters, medication and periodontal burden in patients with rheumatoid arthritis (RA). (Pubmed Central) - May 29, 2020
IL-10 was also elevated with longer duration of prednisolone (< 5 mg daily) and leflunomide therapy...IL-17 was higher in subjects with fewer missing teeth if the following criteria were fulfilled: shorter prednisolone (< 5 mg) and methotrexate therapy, more swollen joints, longer morning stiffness...Subjects suffering from dental/periodontal burden show an aberrant systemic cytokine availability of serum IL-6, IL-10, IL-17 and IL-23 related to disease activity and medication. This examination underlines the complexity of potential interactions between disease activity and medication related to periodontal burden.
- | prednisolone / Generic mfg.
Journal: The exudative-constrictive tuberculosis pericarditis diagnosed by toracoscopic biopsy. (Pubmed Central) - May 29, 2020
Therapy included pyrazinamide, ethambutol, levofloxacin, prednisolone 20 mg / day...The negative results of all laboratory tests for tuberculosis do not exclude the diagnosis. It is necessary to use invasive morphological diagnosis, including thoracoscopic biopsy.
- | prednisolone / Generic mfg.
Journal: Influence of PDLA nanoparticles size on drug release and interaction with cells. (Pubmed Central) - May 29, 2020
It is necessary to use invasive morphological diagnosis, including thoracoscopic biopsy. Prednisolone was effectively entrapped and released from NPs with statistically different medium sizes (i.e., 80 or 120 nm)..
- | doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., bendamustine / SymBio, Mundipharma, Astellas, Generic mfg.
Retrospective data, Journal: Bendamustine for patients with indolent B cell lymphoproliferative malignancies including chronic lymphocytic leukaemia - an updated meta-analysis. (Pubmed Central) - May 27, 2020
Maintenance therapy was not evaluated after bendamustine induction, and potentially there is an interaction between the two. Chemotherapy-free approach was shown to be efficacious for patients with CLL, while toxicity with that approach is not negligible.
- || Rituxan (rituximab) / Roche, Biogen, Zenyaku Kogyo
Clinical, P2 data, Journal: Phase II study of R-CVP followed by rituximab maintenance therapy for patients with advanced marginal zone lymphoma: consortium for improving survival of lymphoma (CISL) study. (Pubmed Central) - May 27, 2020
P2
Rituximab-maintenance therapy following first-line R-CVP demonstrated good PFS in patients with stage III-IV MZL, in addition to a favorable toxicity profile. Trial registration clinicaltrials.gov: NCT01213095.
- | prednisolone / Generic mfg., albendazole / Generic mfg.
Journal: Long-lasting undetected neurocysticercosis. (Pubmed Central) - May 27, 2020
Over a long period of time, the majority of patients develop seizures as the most common symptom, which requires the administration of medications. Proper diagnostic procedures and adequate combination of surgery and conservative treatment areessential.
- || Decadron (dexamethasone) / Merck (MSD)
Clinical, Journal: Pattern of steroid misuse in vernal keratoconjunctivitis resulting in steroid induced glaucoma and visual disability in Indian rural population: An important public health problem in pediatric age group. (Pubmed Central) - May 26, 2020
Weak steroids like loteprednol or fluorometholone should be used instead of higher potency drugs. Vision and IOP should be monitored fortnightly in children using topical steroids to detect steroid responders at the earliest.