- |||||||||| cholestyramine (A3384) / Ipsen
Journal: The Epidemiology of Bile Acid Diarrhea in Denmark. (Pubmed Central) - Dec 13, 2023 The BAD population had more co-morbidities and more health care contacts as well as lower levels of education and income compared with age- and sex-matched controls from the general population. Using the Danish registries, we identified a BAD population, which seems to be inferior in health care and socio-economic parameters compared with the Danish general population.
- |||||||||| Cholebine (colestilan) / Mitsubishi Tanabe
Review, Journal: Bile Acid Sequestrants Based on Natural and Synthetic Gels. (Pubmed Central) - Jun 27, 2023 Focus is given to the understanding of the relationships between the chemical structure of these cross-linked polymers and their potential to bind bile salts. The synthetic pathways used in obtaining BASs and their in vitro and in vivo hypolipidemic activities are also introduced.
- |||||||||| Journal: Lipid-lowering drugs. (Pubmed Central) - Sep 20, 2022
Two-week neratinib DE with loperamide as needed was particularly effective. No abstract available
- |||||||||| loperamide / Generic mfg., colestipol / Generic mfg.
A Case of Progressive Refractory Diarrhea due to Zollinger-Ellison Syndrome (Crown Ballroom) - Sep 4, 2022 - Abstract #ACG2022ACG_3224; The gastric pH, gastric level, secretin stimulation, and Dotatate PET/CT are used to evaluate and localize the tumor. Figure: Figure 1A, 1B: Computed Tomography (CT) abdomen showed multiple, small duodenal ulcers and 4 millimeter (mm) enhancing polyp at the gastric antrum (red arrows)
- |||||||||| The Case of the Disappearing Ducts: Hodgkin’s Lymphoma Presenting With Vanishing Bile Duct Syndrome (Crown Ballroom) - Sep 4, 2022 - Abstract #ACG2022ACG_2920;
Although this case highlights a particular rare entity that may cause cholestatic liver injury in patients with cHL, it is paramount to conduct a thorough evaluation for other potential causes to include infiltrative, viral, obstructive, autoimmune, and drug-induced processes. Figure: Liver Biopsy with IHC stain for CK7 showing disrupted small bile ducts and small duct proliferation
- |||||||||| High-Potency Proton Pump Inhibitor Therapy for the Management of Chronic Hiccups (Crown Ballroom) - Sep 4, 2022 - Abstract #ACG2022ACG_1881;
Prior therapies consisted of chlorpromazine and once daily pantoprazole without benefit...He was recommended to continue baclofen, start colestipol 1 gm daily, and start omeprazole 40 mg twice daily for 3 months...Figure: A) Endoscopic image of distal esophagus and hiatal hernia. B) High-resolution esophageal manometric composite image
- |||||||||| Nerlynx (neratinib) / Puma, Knight Therap, Pierre Fabre
Effect of diarrheal prophylaxis or dose escalation on neratinib-associated diarrhea and tolerability in patients with HER2+ early-stage breast cancer: Final findings from the CONTROL trial (Exhibition area) - Mar 19, 2022 - Abstract #ESMOBC2022ESMO_BC_277; P2 Legal entity responsible for the study Puma Biotechnology Inc.Funding Puma Biotechnology Inc.Neratinib (N), an irreversible pan-HER TKI, is approved in the EU for extended adjuvant treatment of early-stage HR+ HER2+ breast cancer (BC) after adjuvant trastuzumab (T)-based therapy...Pts were enrolled sequentially into separate cohorts: 1) mandatory loperamide prophylaxis; 2) budesonide + loperamide; 3) colestipol + loperamide; 4) colestipol + loperamide PRN; 5) DE + loperamide PRN (2 cohorts)...Conclusions These final findings from CONTROL show improved tolerability of N with all diarrhea prophylaxis strategies and suggest that DE1 with loperamide PRN allows pts to stay on treatm. ent longer and receive full benefit from N.
- |||||||||| loratadine / Sedico, Remedica, Generic mfg., Merck (MSD), Bayer, desmopressin / Generic mfg., colestipol / Generic mfg.
[VIRTUAL] Acute Transient Central Diabetes Insipidus: A Rare Case of DI Secondary to Vasopressin Withdrawal (On-Demand) - Feb 2, 2021 - Abstract #ENDO2021ENDO_1490; His home medications were metoprolol, loratadine and colestipol...He was administered 1mcg desmopressin and his D5W rate was increased...For oral presentations, the abstracts are embargoed until the session begins. The Endocrine Society reserves the right to lift the embargo on specific abstracts that are selected for promotion prior to or during ENDO 2021.
- |||||||||| prednisone / Generic mfg., colestipol / Generic mfg., azathioprine orodispersible / Generic mfg.
[VIRTUAL] The Plot (and Basement Membrane) Thickens: A Case Report of Collagenous Sprue Associated With Collagenous Colitis () - Sep 15, 2020 - Abstract #ACG2020ACG_3271; Budesonide was cost-prohibitive, so she was placed on colestipol and bismuth, and was doing well at five month follow up...The patient went on a gluten free diet and was also placed on azathioprine 0.5 mg/kg, which was titrated up to 1 mg/kg...When patients do not respond to gluten elimination alone, options for immune suppression include budesonide, prednisone, immunomodulators, or biologic therapies...Further study is needed to determine optimal therapy and duration. We report on this interesting clinical entity both to raise awareness of the condition and to remind clinicians of the need to look for alternative etiologies of new GI symptoms when a patient with microscopic colitis develops new and uncontrolled symptoms.
- |||||||||| simvastatin / Generic mfg., Triglide (fenofibrate) / Vectura, Shionogi, Nexletol (bempedoic acid) / Esperion Therap, Otsuka
Journal: Bempedoic acid (Nexletol) for lowering LDL-cholesterol. (Pubmed Central) - May 19, 2020 We report on this interesting clinical entity both to raise awareness of the condition and to remind clinicians of the need to look for alternative etiologies of new GI symptoms when a patient with microscopic colitis develops new and uncontrolled symptoms. No abstract available
- |||||||||| simvastatin / Generic mfg.
Clinical, Review, Journal: Statins for children with familial hypercholesterolemia. (Pubmed Central) - Mar 2, 2020 Children treated with statins should be carefully monitored and followed up by their pediatricians and their care transferred to an adult lipidologist once they reach 18 years of age. Large long-term randomized controlled trials are needed to establish the long-term safety issues of statins.
- |||||||||| colestipol / Generic mfg.
Trial completion: Sorbent Therapy of the Cutaneous Porphyrias (clinicaltrials.gov) - Apr 28, 2013 P2/3, N=4, Completed, Recruiting --> Completed | N=90 --> 30 Active, not recruiting --> Completed
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