lignocaine / Generic mfg. 
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  • ||||||||||  sildenafil / Generic mfg.
    Preclinical, Journal:  The Frequency-Dependence of Pre- and Postganglionic Nerve Stimulation of Pig and Rat Bladder. (Pubmed Central) -  Oct 7, 2021   
    Intramural ganglia offer no frequency-dependent modulation under the experimental conditions used here and the sildenafil data are consistent with multiple sites of action underlying generation of bladder contractions. A translational aspect of these findings is discussed in terms of setting stimulation parameters for neuromodulation protocols.
  • ||||||||||  lignocaine / Generic mfg.
    [VIRTUAL] Pre-emptive Analgesia In Appendectomy With Peritoneal Infiltration: A Randomised Clinical Trial (Channel 1) -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_2713;    
    We aimed to examine the effects of pre-incisional infiltration of bupivacaine and lignocaine during an appendectomy on immediate post-operative pain, post-operative opioids and the time taken to resume normal activity... We conclude that preemptive analgesia with pre-incisional peritoneal infiltration of bupivacaine and lidocaine with adrenaline is a safe and effective method of pain relief after appendectomy.
  • ||||||||||  chlorpheniramine / Generic mfg., lignocaine / Generic mfg.
    Anaphylaxis?.... Not always! () -  Oct 1, 2021 - Abstract #EUSEM2021EUSEM_1613;    
    A presumptive diagnosis of anaphylaxis to lignocaine was made and the patient was treated with IM adrenaline, IV steroids, and salbutamol nebuliser...Additional IM adrenaline and IV chlorphenamine was given at this point...In this case, it is unclear why the subcutaneous emphysema continued to worsen after the original endodontic procedure was performed, but no other cause was identified. Conclusion Even in presentations where the most likely differential diagnosis is an allergic/anaphylactic reaction, a thorough examination and history should be sought, especially if the patient fails to improve with initial therapy.
  • ||||||||||  chlorpheniramine / Generic mfg., lignocaine / Generic mfg.
    Anaphylaxis?.... Not always! () -  Oct 1, 2021 - Abstract #EUSEM2021EUSEM_1612;    
    A presumptive diagnosis of anaphylaxis to lignocaine was made and the patient was treated with IM adrenaline, IV steroids, and salbutamol nebuliser...Additional IM adrenaline and IV chlorphenamine was given at this point...In this case, it is unclear why the subcutaneous emphysema continued to worsen after the original endodontic procedure was performed, but no other cause was identified. Conclusion Even in presentations where the most likely differential diagnosis is an allergic/anaphylactic reaction, a thorough examination and history should be sought, especially if the patient fails to improve with initial therapy.
  • ||||||||||  chlorpheniramine / Generic mfg., lignocaine / Generic mfg.
    Anaphylaxis?.... Not always! () -  Oct 1, 2021 - Abstract #EUSEM2021EUSEM_1611;    
    A presumptive diagnosis of anaphylaxis to lignocaine was made and the patient was treated with IM adrenaline, IV steroids, and salbutamol nebuliser...Additional IM adrenaline and IV chlorphenamine was given at this point...In this case, it is unclear why the subcutaneous emphysema continued to worsen after the original endodontic procedure was performed, but no other cause was identified. Conclusion Even in presentations where the most likely differential diagnosis is an allergic/anaphylactic reaction, a thorough examination and history should be sought, especially if the patient fails to improve with initial therapy.
  • ||||||||||  chlorpheniramine / Generic mfg., lignocaine / Generic mfg.
    Anaphylaxis?.... Not always! () -  Oct 1, 2021 - Abstract #EUSEM2021EUSEM_1610;    
    A presumptive diagnosis of anaphylaxis to lignocaine was made and the patient was treated with IM adrenaline, IV steroids, and salbutamol nebuliser...Additional IM adrenaline and IV chlorphenamine was given at this point...In this case, it is unclear why the subcutaneous emphysema continued to worsen after the original endodontic procedure was performed, but no other cause was identified. Conclusion Even in presentations where the most likely differential diagnosis is an allergic/anaphylactic reaction, a thorough examination and history should be sought, especially if the patient fails to improve with initial therapy.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date:  Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers (clinicaltrials.gov) -  Sep 8, 2021   
    P=N/A,  N=230, Enrolling by invitation, 
    Trial completion date: Aug 2021 --> Mar 2022 | Trial primary completion date: Jul 2021 --> Mar 2022 Trial completion date: Dec 2023 --> Dec 2025 | Trial primary completion date: Dec 2023 --> Dec 2025
  • ||||||||||  lignocaine / Generic mfg.
    Clinical, Journal:  Comparison of efficacy of lignocaine, ropivacaine, and bupivacaine in pain control during extraction of mandibular posterior teeth. (Pubmed Central) -  Sep 7, 2021   
    Also, postoperative pain was noted in 60% of cases who underwent extraction using 2% lignocaine (Group I), 10% patients who had third molar extractions under Bupivacaine anesthesia presented with pain whereas none of the patients (0%), demonstrated the presence of pain following third molar extraction. 0.75% Ropivacaine is the most effective local anesthetic agent that can be used for extracting mandibular third molars due to its effective pain control both during and following the procedure when compared to 2% lignocaine and bupivacaine.
  • ||||||||||  chlorpheniramine / Generic mfg., lignocaine / Generic mfg.
    Anaphylaxis?.... Not always! (Posters) -  Sep 7, 2021 - Abstract #EUSEM2021EUSEM_109;    
    A presumptive diagnosis of anaphylaxis to lignocaine was made and the patient was treated with IM adrenaline, IV steroids, and salbutamol nebuliser...Additional IM adrenaline and IV chlorphenamine was given at this point...In this case, it is unclear why the subcutaneous emphysema continued to worsen after the original endodontic procedure was performed, but no other cause was identified. Conclusion Even in presentations where the most likely differential diagnosis is an allergic/anaphylactic reaction, a thorough examination and history should be sought, especially if the patient fails to improve with initial therapy.
  • ||||||||||  ibuprofen / Generic mfg.
    Journal:  Hydrotropic Solubilization in Pharmaceutical Analysis: Origin, Evolution, Cumulative Trend and Precise Applications. (Pubmed Central) -  Sep 2, 2021   
    The obvious purpose of this study was to collectively evaluate the crucial role of hydrotropic agents in pharmaceutical analyses for better drug delivery. This comprehensive review covers all details since inception to the updates till date which will definitely act as appropriate guideline for pharmaceutical analyst's in need of hydrotropy to assist pharmaceutical analysis for therapies today and tomorrow.
  • ||||||||||  remifentanil / Generic mfg., lignocaine / Generic mfg.
    Trial completion, Trial completion date, Surgery:  Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery (clinicaltrials.gov) -  Aug 25, 2021   
    P4,  N=156, Completed, 
    It also showed how prices for a service can rise following such a decision, which demonstrates the concept of negative general deterrence in sentencing. Recruiting --> Completed | Trial completion date: Nov 2021 --> Jul 2021
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Effect of a Topical Formulation on Infective Viral Load in Lambs Naturally Infected with Orf Virus. (Pubmed Central) -  Jun 22, 2021   
    The wound dressing formulation Tri-Solfen containing two local anaesthetics (lignocaine and bupivacaine), adrenaline and an antiseptic (cetrimide) in a gel formulation was developed for pain relief in sheep undergoing surgical husbandry procedures in Australia...Although no significant differences were found in the clinical progression of the lesions and PCR quantification (p=0.722) between these small cohorts, there was a significant difference (p<0.05) in reduction in infective viral load between the groups when assessed in OSF cell cultures between T0 and T3. These preliminary findings suggest that treatment of early stage lesions with this TS may reduce the infective viral load present in orf lesions.
  • ||||||||||  triamcinolone acetonide / Generic mfg., lignocaine / Generic mfg.
    Enrollment open, Trial primary completion date, Stroma:  Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids (clinicaltrials.gov) -  Jun 18, 2021   
    P2,  N=30, Recruiting, 
    Thiopentone with 10% topical Lignocaine is an alternative for the insertion of LMA to Propofol, with better hemodynamic stability and cost-effectiveness. Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2021 --> Dec 2021
  • ||||||||||  lignocaine / Generic mfg.
    Review, Journal:  Structured review of primary interventions to reduce group A streptococcal infections, acute rheumatic fever and rheumatic heart disease. (Pubmed Central) -  Jun 9, 2021   
    This review has identified that there is little available evidence for effective primary prevention strategies to reduce ARF rates in NZ. However, two primary intervention strategies that should be considered by communities at high-risk of ARF are: the use of school-based clinics to identify and treat GAS pharyngitis and GAS skin infections; and intramuscular benzathine penicillin G with lignocaine analgesia in children who present with a GAS positive throat.